Clinical trials: Acute Conditions
Inflammation, Oxidative Stress
Comparison of Acute Tart Cherry Supplement Formulation and Dose on Inflammation and Oxidative Capacity
A comparison of acute tart cherry formations (juice vs. powdered) and doses (single vs. twice daily) on inflammation and oxidative capacity.
- Trial name
- NCT04497077
- Testing
- tart cherry
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ohio University
Fetal Growth Retardation, Fetal Growth Complications
Acute Effects of Maternal Exercise and the Growth Restricted Pregnancy
Objectives / Specific Aims The purpose of this study is to investigate the acute effects of a single bout of moderate intensity maternal exercise on fetal well-being in a pregnancy affected by fetal growth restriction.
- Conditions
- Fetal Growth Retardation, Fetal Growth Complications, Placental Insufficiency
- Trial name
- NCT06039319
- Testing
- Physical activity
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Tennessee Graduate School of Medicine
Sepsis, Acute Lung Injury
Biological Markers to Identify Early Sepsis and Acute Lung Injury
There are no clear markers to identify sepsis and acute lung injury at early stage in clinical settings which would result in improved survival of the patients. In collaboration with the research team led by Dr. Zhang at St.
- Trial name
- NCT00825357
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chimei Medical Center
Malnutrition; Diabetes, Malnutrition; Protein
Impact of Pea, Lentil and Oat Flour Particle Size on Glycemic Response in Healthy Adults
The study looks at the comparative effects of food products made with pea, lentil, and oat flour of various particle sizes on postprandial glycemic response, appetite and food intake, and amino acid release in healthy adults.
- Conditions
- Malnutrition; Diabetes, Malnutrition; Protein, Obesity
- Trial name
- PLO (NCT05291351)
- Testing
- Crackers made with whole, coarse, or fine pea and/or wheat flour, Crackers made with whole, coarse, or fine lentil and/or wheat flour, Porridge made with oat flour
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Field Physician Care, Analgesics
Analgesia in ÖAMTC Helicopter Emergency Service in Austria
A sufficient analgesia in injured or sick people is the main goal of physicians treating a patient. In emergency medicine potent analgesia like ketamine or opioids are routinely used.
- Conditions
- Field Physician Care, Analgesics, Hypnotics, Emergencies
- Trial name
- NCT03760302
- Testing
- analgesics, hypnotics
- Where
- Austria
- Volunteers
- 35,000 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Disc Degenerative Disease, Spine Degeneration
Physiotherapy and Osteopathic Treatment for Pain in the Cervical and Lumbar Spine and Temporomandibular Joints
Study Summary: Effectiveness of Physiotherapy and Osteopathy in Treating Spinal and Temporomandibular Joint Pain About the Study and Its Objective This study is conducted by Artur Hołodniuk, MSc, a physiotherapist and academic…
- Conditions
- Disc Degenerative Disease, Spine Degeneration, Back Ache, Temporomandibular Disorder (TMD)
- Trial name
- NCT07830836
- Testing
- General Osteopathic Treatment, Visceral Therapy, Magnetic field therapy
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Chronic Fatigue Syndrome, Long COVID
Endothelial Dysfunction in Post-infection Fatigue Syndromes
Post-infection chronic fatigue syndromes, such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-COVID-19 condition (Long Covid), are conditions primarily characterized by debilitating fatigue.
- Trial name
- NCT06463106
- Where
- Austria
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- FH Joanneum Gesellschaft mbH
Pain, Acute, Surgical Procedure, Unspecified
Surgical Intervention in Deep Sedation: No Pain or no Memory
The goal of this observational study is to assess the levels of nociception in deeply sedated patients who need painful and short-duration surgical procedure.
- Trial name
- SedNOL (NCT06963749)
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- ASL Novara
Inflammation Biomarkers, Inflammation
Individual Differences in Acute Response to Experimental Inflammation: Microcirculatory Changes and Psychological Predictors
The physiological and behavioral responses to inflammatory vary greatly between individuals. The knowlegde about what causes these differences is sparse but plausible explanations are variations in sensitivity to peripheral…
- Trial name
- NCT06618716
- Testing
- endotoxin escherichia coli (E. coli) lipopolysaccharide (LPS), Placcebo
- Where
- Sweden
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Low Back Pain, Kinesio Taping
Acute Effect of Myofascial Release and Kinesiology Taping
Chronic low back pain (LBP) is one of the leading causes of activity limitation and disability. The prevalence of chronic CBA among young adults is known to increase, and a recent epidemiological study reported a rate of 42.4%…
- Conditions
- Low Back Pain, Kinesio Taping, Myofascial Release Technique
- Trial name
- NCT05319184
- Testing
- Myofascial Release Technique and Kinesiology Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pain, Acute, Patient Satisfaction
Pilot Trial: Comparing Buzzy to Intradermal Lidocaine for Peripheral IV Cannulation in Adults
IV placement is necessary for surgical procedures. Unfortunately, some patients say that placing an IV is painful. The investigators are conducting this study to evaluate two techniques that could make the placement of the IV…
- Trial name
- NCT04647084
- Testing
- Lidocaine 2% Injectable Solution, Buzzy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Pain, Acute
Transauricular Vagal Nerve Stimulation, Pressure Pain and Interoception
Interoception, the ability to perceive, process and respond to signals originating from within the body, is crucial for maintaining healthy physiological ranges.
- Trial name
- NCT06240026
- Testing
- taVNS, Earlobe Stimulation
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Consciousness Disorder
Outcome Prediction in Patients With Acute Disorders of Consciousness
Prior research has indicated a link between outcomes in patients with disorders of consciousness (DOC) and their responses to emotional auditory stimuli.
- Trial name
- NCT04411719
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Skeletal Muscle Protein Synthesis in Elderly, Protein Kinetics
Effect of Low Intensity Exercise and Protein Intake on Skeletal Muscle Protein Synthesis in Elderly
Maintenance of skeletal muscle mass is crucial during lifespan to retain health and functional autonomy. Sarcopenia, being the loss of muscle mass during aging, is a well-known phenomenon in the elderly and a major challenge…
- Conditions
- Skeletal Muscle Protein Synthesis in Elderly, Protein Kinetics, Sarcopenia
- Trial name
- NCT01640145
- Testing
- Protein, Exercise
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Cognitive Change, Mood
The Effects of Resveratrol Supplementation on Inflammation and Cognitive Performance in Healthy Adults
Previous research has suggested that high levels of systemic inflammation can contribute to cognitive deficits and additional health problems; consumption of polyphenols have been shown to have an anti-inflammatory effect.
- Conditions
- Cognitive Change, Mood, Systemic Inflammation
- Trial name
- NCT04314739
- Testing
- Resveratrol
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Emergency Service, Hospital, Child/Adolescent Problem
A RCT of a Combination of Analgesics for Pain Management in Children With a Suspected Fracture
MSK-I is the most common cause for ED visits for children with pain, with a child's risk of sustaining a fracture ranging from 27-42% by the age of 16 years.
- Conditions
- Emergency Service, Hospital, Child/Adolescent Problem, Acute Pain, Fentanyl
- Trial name
- CAST (NCT02985177)
- Testing
- INF2.0 + IBU, INF1.0 + IBU
- Where
- 3 sites in Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Obesity, Healthy
The Effect of Acute and Chronic Exercise at the Metabolic Syndrome and Markers of Inflammation in Obese Subjects
The human adipose and muscle -tissue produce and release a number of bioactive proteins which contributes to the chronic low grade of inflammatory status which is associated with obesity and plays an important role in the…
- Trial name
- NCT00700245
- Testing
- Exercise-only (EXO-12 weeks of regular supervised exercise without diet restriction), Diet-only (DIO-8 weeks of very low energy diet (VLED 600 kcal/d) followed by 4 weeks weight maintenance diet, Diet+exercise (DEX-8 weeks VLED 800 kcal/d + a four weeks weight maintenance diet combined with regular supervised exercise throughout the 12 weeks).
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Tinnitus, Subjective
Treatment for Post Acute COVID-19 Syndrome
Post-acute COVID-19 tinnitus has not been treated successfully. As tinnitus may be related to SARS-CoV-2 neurological manifestations.
- Trial name
- NCT05507372
- Testing
- Pimozide 1 MG
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Applied Biology, Inc.
Pain, Neuropathic, Pain, Acute
Ice Immersion Using Virtual Reality & Augmented Reality
The purpose of this study is to evaluate the effectiveness of different technologies, Virtual Reality and Augmented Reality with modifications as passive content, active content, cognitive load modulation, and positive…
- Trial name
- NCT04196686
- Testing
- VR/AR, Ice Bath
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Stanford University
PASC Post Acute Sequelae of COVID-19
Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC)
This study uses total-body [¹⁸F]F-AraG PET/CT imaging to investigate immune activation and vascular changes in individuals with post-acute sequelae of SARS-CoV-2 infection (PASC), also known as Long COVID.
- Trial name
- NCT07076862
- Testing
- A.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static), A.2 - [¹⁸F]F-AraG PET/CT (60-min dynamic only), B.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static)
- Where
- 2 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.