Clinical trials: Acute Conditions
Myelodysplastic Syndromes, Leukemia Myeloid Acute
A Study to Determine Final Geriatric Assessment in Haematology (GAH) Score as a Tool for Predicting Tolerance to Treatment in Elderly Patients (≥ 65 Years) With Haematologic Neoplasms
This is a post-authorization, retrospective multicentre observational nationwide study (PAS-OD). It will be conducted by reviewing medical records and database of patients who participated in the validation of the psychometric…
- Conditions
- Myelodysplastic Syndromes, Leukemia Myeloid Acute, Multiple Myeloma, Leukemia, Lymphocytic, Chronic, B-Cell
- Trial name
- NCT02842229
- Where
- 15 sites in Spain
- Volunteers
- 117 people
- Sponsor
- Celgene
Acute Myeloid Leukemia (AML), Acute Lymphocytic Leukemia in Relapse
Yoga Fatigue Study
Fatigue is a major problem in children, adolescents and adults receiving intensive chemotherapy for cancer and in patients undergoing hematopoietic stem cell transplantation (HSCT).
- Conditions
- Acute Myeloid Leukemia (AML), Acute Lymphocytic Leukemia in Relapse, Burkitt's Lymphoma Stage III, Burkitt's Lymphoma Stage IV
- Trial name
- NCT02134782
- Testing
- Individualized Yoga Intervention Group, iPad Activity Control Group
- Where
- 3 sites in United States, Canada
- Volunteers
- 125 people
- Sponsor
- The Hospital for Sick Children
Acute Myocardial Infarction, Stable Angina
Development and Efficacy Evaluation of Integrated Chronic Care and Health Promotion Model for Patients With Coronary Artery Disease in Taiwan
The hypothesis of this project is to examine whether the integrated health care program as the intervention group can reduce the recurrence and mortality of coronary artery-related diseases than the traditional one as the…
- Trial name
- NCT01357096
- Testing
- Integrated health care team, Traditional group
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Acute Respiratory Failure
Hyperangulated Versus Standard Geometry Laryngoscope Blade Trial
The Hyperangulated versus Standard Geometry Laryngoscope Blade (ANGLE) Trial is a multi-center, non-blinded, parallel-group, randomized clinical trial evaluating the effect of use of a hyperangulated video laryngoscope blade…
- Trial name
- ANGLE (NCT07223762)
- Testing
- Hyperangulated video laryngoscope blade, Standard geometry video laryngoscope blade
- Where
- 19 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- Vanderbilt University Medical Center
Acute Coronary Syndrome, Angina Pectoris
Diagnostic Performance of Artificial Intelligence Algorithms in Prediction of Acute Coronary Syndrome Based on White Blood Cell Properties
The goal of this observational study is to evaluate whether artificial intelligence (AI) algorithms can predict or exclude acute coronary syndrome (ACS) in adults using data generated by routine hematology testing.
- Conditions
- Acute Coronary Syndrome, Angina Pectoris, NSTEMI - Non-ST Segment Elevation MI, STEMI - ST Elevation Myocardial Infarction
- Trial name
- NCT06384846
- Where
- Austria
- Volunteers
- 3,350 people, healthy volunteers welcome
- Sponsor
- RobotDreams GmbH
Pain, Acute
Distraction as Treatment for Pain in Children in Resource-scarce Settings
Pain alleviation in pediatric patients can be challenging for medical professionals working in resource scarce settings due to limited availability of medication, monitoring equipment, or training in this field of expertise.
- Trial name
- DISTRACT (NCT06933303)
- Testing
- Distraction with kaleidoscope
- Where
- South Africa
- Volunteers
- 126 people
- Sponsor
- Vrinnevi Hospital
Heart Failure
Improving Risk Stratification of Emergency Department Patients With Acute Heart Failure
The primary goal is to build and test a previously developed and validated risk model and clinical decision support tool embedded within the electronic health record to improve risk stratification of emergency department (ED)…
- Trial name
- NCT06065761
- Testing
- Comprehensive ED heart failure management tool
- Where
- 21 sites in United States
- Volunteers
- 17,459 people
- Sponsor
- Kaiser Permanente
Respiratory Distress Syndrome, Adult
Evaluation of Safety & Efficacy of BIO-11006 Inhalation Solution in Patients With ARDS
This Phase IIa pilot study is a placebo controlled, multicenter study to evaluate safety and efficacy of aerosolized BIO-11006 Inhalation Solution in ARDS patients.
- Trial name
- NCT03202394
- Testing
- BIO-11006
- Where
- 5 sites in United States
- Volunteers
- 38 people
- Sponsor
- BioMarck Pharmaceuticals, Ltd.
Eating Disorders, Anxiety
Non-invasive Cranial Electrical Stimulation for Mealtime Anxiety in Adults With Eating Disorders
The study is to evaluate the feasibility of using a non-invasive brain stimulation device in a sample of inpatients with eating disorders (ED).
- Trial name
- NCT07017322
- Testing
- Alpha-Stim AID
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Rogers Behavioral Health
Acute Asthma
Feasibility of an ED Initiated Online Asthma Management Program for Urban Teens
The objective of this study is to determine the feasibility of conducting a randomized controlled trial to evaluate the effectiveness of an online, Emergency Department-initiated asthma management intervention designed to reduce…
- Trial name
- PuffCityED (NCT01695031)
- Testing
- Tailored asthma management program, Generic web-based education
- Where
- 2 sites in United States
- Volunteers
- 126 people
- Sponsor
- Henry Ford Health System
Pulpitis, Acute Pain
Effect of Low Power Laser in Tooth Pain Modulation Caused by Irreversible Inflammation
Anxiety, pain and discomfort are common stressful situations that occur during the dentistry practice, especially in the urgency endodontic practice.
- Trial name
- NCT02169102
- Testing
- No additional Intervention (control), Laser 1 (at 0,16 Joules/point of irradiation), Laser 2 (1,6 Joules/point of irradiation)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Postoperative Pain, Acute, Regional Anesthesia
Comparation of Bilateral and Unilateral Erector Spinae Plane Block
Although laparoscopic cholecystectomy is a minimally invasive surgery with many advantages, it is one of the operations with high postoperative pain scores. Opioids are frequently used to prevent postoperative pain.
- Conditions
- Postoperative Pain, Acute, Regional Anesthesia, Multimodal Analgesia
- Trial name
- NCT05152602
- Testing
- Bilateral Erector spinae plane block, Unilateral Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara City Hospital Bilkent
Autoimmune Diseases, Cardiovascular Disorders
Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
This multi-arm, multi-site study investigates the safety, tolerability, and efficacy of stem cell therapy for the treatment of various acute and chronic conditions.
- Conditions
- Autoimmune Diseases, Cardiovascular Disorders, Diabetes Complications, Integumentary Disease
- Trial name
- NCT04684602
- Testing
- PrimePro™/ PrimeMSK™
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Thomas Advanced Medical LLC
Heart Failure
Patient Journey in Hospital With Heart Failure in Turkish Population
The purpose of this study is to compose a national database of the etiologies, clinical and demographic characteristics, using diagnostic tests, precipitating and risk factors, management of from intensive care unit or coronary…
- Trial name
- JournayHF-TR (NCT02487056)
- Testing
- Demographic and clinical characteristics, clinical history, symptoms and signs, initial emergency department evaluation, and subsequent inpatient management of HF patients
- Where
- Turkey (Türkiye)
- Volunteers
- 1,622 people
- Sponsor
- Ege University
End-stage Chronic Renal Disease, Severe Acute Kidney Failure
Renal Transplantation and Inhaled Anesthetic Sevoflurane (SEVOREIN)
Renal transplantation is characterized by ischemia-reperfusion lesions in allograft. In a previous study, Julier and al. (Anesthesiology 2003) have demonstrated that sevoflurane reduces glomerular lesions in kidney of patients…
- Conditions
- End-stage Chronic Renal Disease, Severe Acute Kidney Failure, Renal Transplantation
- Trial name
- SévoRein (NCT00337051)
- Testing
- Sevoflurane, Propofol
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Bordeaux
Acute Brain Injuries, Consciousness Disorders
CONNECT-ME: Consciousness in Neurocritical Care Cohort Study Using fMRI and EEG
Detecting preserved consciousness in brain-injured patients by traditional clinical means requires presence of motor function. Otherwise, patients may be erroneously classified as being in a vegetative state.
- Trial name
- CONNECT-ME (NCT02644265)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Myocardial Infarction
Remote Ischemic Preconditioning in Primary PCI
Primary percutaneous coronary intervention (pPCI) is the preferred treatment in ST elevation myocardial infarction (STEMI). The infarct-related artery (IRA) can be opened in more than 90% of the patients.
- Trial name
- NCT00435266
- Testing
- Remote ischemic preconditioning
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Sudden Cardiac Death, Acute Coronary Event
Finnish Genetic Study for Arrhythmic Events
Finnish Genetic Study for Arrhythmic Events (FinGesture is a prospective case-control study assessing the characteristics and genetic background of consecutive series of autopsy verified out-of-hospital victims of SCD vs.
- Trial name
- FinGesture (NCT02075866)
- Where
- Finland
- Volunteers
- 8,000 people
- Sponsor
- University of Oulu
ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention
The EPIVER Randomized Controlled Trial
The trial aims to estimate the efficacy and safety of the intracoronary administration of adrenalin, verapamil, as well as their combination compared to standard treatment in patients with STEMI and refractory coronary no-reflow…
- Conditions
- ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention, No-Reflow Phenomenon
- Trial name
- EPIVER (NCT04573751)
- Testing
- Standard therapy, Epinephrine, Verapamil
- Where
- Russia
- Volunteers
- 104 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Accidental Falls, Cross Infection (Hospital-Acquired Infections)
Impact of Primary Nursing on Nursing-sensitive Outcomes in Inpatients Units: a Multicentre Pre-Post Study
The aim of this quasi-experimental before-after study is to evaluate whether the implementation of the Primary Nursing (PN) pattern of care improves nursing-sensitive outcomes in adult inpatients and nurse-related outcomes across…
- Conditions
- Accidental Falls, Cross Infection (Hospital-Acquired Infections), Acute Care Unit
- Trial name
- PRIMARY (NCT07687251)
- Testing
- Primary Nursing
- Where
- 5 sites in Italy
- Volunteers
- 1,708 people
- Sponsor
- Università degli Studi del Piemonte Orientale Amedeo Avogadro
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