Clinical trials: Acute Conditions
Acute Mesenteric Ischemia
ORal Antibiotics in Acute Mesenteric Ischemia
Acute mesenteric ischemia (AMI) is a life-threatening condition with an increasing incidence (7-13/100000 PY). The mortality of AMI is associated with the development and extent of transmural intestinal necrosis (IN), ranging…
- Trial name
- ORIAMI (NCT06387147)
- Testing
- Gentamicin, Metronidazole
- Where
- 4 sites in France
- Volunteers
- 196 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Postoperative Pain, Hemorrhoids Third Degree
Efficacy of Ice Packing Application in Post-Hemorrhoidectomy Recovery
According to the previous study, surgical intervention exhibited significant differences in daily life before and after a hemorrhoidectomy.
- Conditions
- Postoperative Pain, Hemorrhoids Third Degree, Hemorrhoids Fourth Degree, Hemorrhoids
- Trial name
- ICE-HEMO (NCT07186348)
- Testing
- Ice packing, Standard Care (in control arm)
- Where
- Taiwan
- Volunteers
- 429 people
- Sponsor
- Chang Gung Memorial Hospital
Long-COVID, Long COVID-19
Pursuing Reduction in Fatigue After COVID-19 Via Exercise and Rehabilitation (PREFACER): A Randomized Feasibility Trial
Long COVID is a complex condition that affects approximately 1.4 million Canadians following SARS-CoV-2 infection. Fatigue is the most common symptom of Long COVID.
- Conditions
- Long-COVID, Long COVID-19, Post-COVID-19 Syndrome, Post-COVID Syndrome
- Trial name
- PREFACER (NCT06156176)
- Testing
- COVIDEx
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Lawson Research Institute of St. Joseph's
Pneumothorax; Acute, Trauma Chest
Occult Pneumothorax in Patients With Blunt or Penetrating Trauma
Pneumothorax is a common life-threatening complication, frequently seen in patients who have been admitted to the emergency department and intensive care unit.
- Trial name
- NCT04188938
- Testing
- Evaluation of occult pneumothorax in who had a blunt or penetrating chest trauma
- Volunteers
- 105 people
- Sponsor
- European University of Lefke
Tinnitus, Acute
In This Study, we Are Testing Whether Combining Two Interventions, in the Early Stages of Tinnitus, is More Effective in Quieting Tinnitus Than Using One Treatment Alone in the Later Stages of Tinnitus
Tinnitus affects one in seven adults long-term Once present persistently for 4 weeks, tinnitus does not usually disappear People generally become less aware of, and less affected by, their tinnitus over time Only one in six…
- Trial name
- ATtDCS (NCT07128004)
- Testing
- tDCS, sound therapy
- Volunteers
- 80 people
- Sponsor
- Newcastle University
Acute Care Medical
More-2-Eat; Implementation of INPAC
M2E is a developmental evaluation of the implementation of the Integrated Nutrition Pathway for Acute Care, in five medical units in five hospitals in Canada.
- Trial name
- m2E (NCT02800304)
- Where
- 5 sites in Canada
- Volunteers
- 5,995 people
- Sponsor
- University of Waterloo
Stroke
Safety Study of External Counterpulsation as a Treatment for Acute Ischemic Stroke
The purpose of this study is to determine if external counterpulsation (ECP) is feasible to perform, tolerable, and safe as a treatment for patients with acute ischemic stroke (i.e., a blockage of one of the arteries supplying a…
- Trial name
- CUFFS (NCT00983749)
- Testing
- Full-pressure ECP
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- University of California, San Diego
Critical Illness
Effect of Combined IV Bolus Amino Acid Supplementation and Mobilisation on Skeletal Muscle During the First 10 Days in the ICU: A RCT
A single-centre, two-arm, parallel randomised controlled trial (RCT) to compare the combined effect of early intravenous bolus amino acid supplementation and mobilisation versus standard of care on changes in muscle mass over the…
- Trial name
- ProMob-ICU (NCT04099108)
- Testing
- Combined cycle ergometry and bolus amino acid supplementation
- Where
- South Africa
- Volunteers
- 50 people
- Sponsor
- University of Stellenbosch
Opioid-Related Disorders, Pain, Acute
A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of a New and a Marketed Tablet Formulation Under Fasted and Fed Conditions in Healthy Adults
This clinical trial is being conducted to compare concentrations of hydrocodone and acetaminophen in the blood after administration of a new and a marketed tablet formulation under fasted and fed conditions in healthy adults.
- Conditions
- Opioid-Related Disorders, Pain, Acute, Pain, Postoperative
- Trial name
- NCT03137017
- Testing
- Norco 5Mg-325Mg Tablet, GRT7014 - Abuse Deterrent Tablet
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Acute; Myocardial Infarction, Complications, Cardiogenic Shock
Mild Hypothermia in Cardiogenic Shock Complicating Myocardial Infarction
Prospective, randomized, single-center, controlled, open-label Pilot-study to investigate whether induction of mild hypothermia in addition to primary percutaneous coronary intervention and optimal medical therapy in myocardial…
- Trial name
- SHOCK-COOL (NCT01890317)
- Testing
- Mild hypothermia
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Leipzig
Ventricular Fibrillation, Ventricular Tachycardia
Further Acute Research of a Subcutaneous Implantable Defibrillator (S-ICD) System
The purpose is to further evaluate the operation, safety, and feasibility of a subcutaneous implantable defibrillator (S-ICD) system in patients who require an implantable cardioverter defibrillator (ICD)for treating ventricular…
- Trial name
- NCT00399217
- Testing
- Subcutaneous Implantable Defibrillator (S-ICD) system, ICD
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- Boston Scientific Corporation
Postoperative Pain, Postoperative Pain, Acute
Incidence of Chronic Pain After Sternotomy
Chronic postoperative pain is a well-known problem. Chronic postoperative pain is defined as pain that begins following a surgical procedure and persists for more than 2 months without other obvious causes such as infection or…
- Conditions
- Postoperative Pain, Postoperative Pain, Acute, Postoperative Pain, Chronic, Sternotomy
- Trial name
- NCT05357963
- Testing
- Sternotomy application
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Ankara City Hospital Bilkent
COPD, COPD Exacerbation Acute
Multiparametric Home Telemonitoring of Patients With Chronic Obstructive Pulmonary Disease Exacerbation
Chronic obstructive pulmonary disease (COPD) exacerbations are risk factors for disease progression and short-term re- hospitalizations.
- Trial name
- NCT06331416
- Testing
- Telemonitoring
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Trieste
Frailty, Sarcopenia
The SHAPE Project (Hospital System for Physical Activity and Active Participation) After Hospitalized Decompensation of Respiratory Chronic Diseases
It is widely established that a lack of adapted physical activity (APA) and sedentary behaviors increase the prevalence of frailty, which exacerbates chronic diseases.
- Conditions
- Frailty, Sarcopenia, Hospital Discharge, Physical Activity
- Trial name
- SHAPE (NCT07663955)
- Testing
- Hospital System for Physical Activity and Active Participation
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Universitari de Bellvitge
Heart Rate Variability, Acute Myocardial Infarction
Effects of Zazen Meditation in Patients With Acute Myocardial Infarction - Randomized Clinical Trial
Introduction: Coronary Artery Disease (CAD) remains the leading cause of death in Brazil, with literature indicating that in patients post-acute myocardial infarction, reduced Heart Rate Variability (HRV) has been established as…
- Trial name
- NCT06562478
- Testing
- Zazen Meditation
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Acute Kidney Injury, Hemorrhage
Efficacy and Safety of Heparin-grafted Membrane for CRRT
The investigators hypothesize that the use of heparin-grafted membrane versus conventional membrane in critically-ill patients with bleeding-risk undergoing continuous renal replacement therapy, will effectively prolong the…
- Conditions
- Acute Kidney Injury, Hemorrhage, Coagulopathy
- Trial name
- CARROM (NCT01779635)
- Testing
- oXiris as first filter, M150 as first filter
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- National University Hospital, Singapore
Postoperative Pain, Postoperative Acute Pain
Comparative Analysis of the Impact of Transversus Abdominis Plane Block on Post-Cesarean Pain Management Using Low Concentration Ropivacaine 0,2%
The goal of this clinical trial is to evaluate whether the addition of a Transversus Abdominis Plane (TAP) block improves postoperative outcomes in women undergoing cesarean section.
- Trial name
- NCT07604376
- Testing
- Postoperative analgesia using TAP block, Ropivacaine 0,2%, volume: 0,4 ml/kg per side, Postoperative pain management using "traditional" analgesia iv regime
- Where
- Romania
- Volunteers
- 70 people
- Sponsor
- Matild Keresztes
Acute Leukemia, Anorexia
Aromatherapy and Essential Oils in Improving Insomnia and Other Symptoms in Patients With Newly Diagnosed Acute Leukemia Undergoing Chemotherapy
This randomized clinical trial studies aromatherapy and essential oils in improving insomnia and other symptoms in patients with newly diagnosed acute leukemia.
- Conditions
- Acute Leukemia, Anorexia, Anxiety, Depression
- Trial name
- NCT02445378
- Testing
- Aromatherapy and Essential Oils, Questionnaire Administration
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Acute Gastroenteritis, Viral Illness
Multi-DOSE Oral Ondansetron for Pediatric Acute GastroEnteritis
A phase III, double-blind, parallel-design, randomized, placebo-controlled trial to compare multi-dose oral Ondansetron with placebo as treatment for vomiting secondary to acute gastroenteritis (AGE), after Emergency Department…
- Conditions
- Acute Gastroenteritis, Viral Illness, Vomiting, Diarrhea
- Trial name
- DOSE-AGE (NCT03851835)
- Testing
- Ondansetron Oral Solution
- Where
- 6 sites in Canada
- Volunteers
- 1,030 people
- Sponsor
- University of Calgary
Delirium - Postoperative, Anxiety Acute
Pediatric Recovery Delirium in Pediatric Patients Undergoing Surgery
The primary aim of this observational study is to evaluate the effect of playing a mother's voice to a child while the patient is being awakened from anesthesia on postoperative delirium.
- Trial name
- Delirium (NCT07413289)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Enes Celik
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