Clinical trials: Acute Coronary Disease
STEMI, Multi Vessel Coronary Artery Disease
STaged Interventional Strategies for Acute ST-seGment Elevation Myocardial Infarction Patient With Multi-vessel Disease（STAGED）
An investigator-initiated, randomized, multicenter, two-arm, open-label study of consecutive patients presenting with STEMI and MVD Objectives: The present study aimed to investigate the difference in major adverse cardiac event…
- Conditions
- STEMI, Multi Vessel Coronary Artery Disease, Percutaneous Coronary Intervention, AMI Patients With Multivessel Disease, Staged PCI
- Trial name
- SAGED (NCT04918030)
- Testing
- Early staged PCI, Late staged PCI
- Where
- China
- Volunteers
- 1,586 people
- Sponsor
- Xiamen Cardiovascular Hospital, Xiamen University
Extracorporeal Membrane Oxygenation Complication, Neonatal Aspiration Pneumonia
Evaluating the Safety and Performance of the MiniLung Petite Kit in Neonatal and Pediatric Patients With Acute Respiratory and Cardiac Failure
This prospective observational study will evaluate the safety and performance of the MiniLung petite kit in neonatal and pediatric patients with acute respiratory and cardiac failure.
- Conditions
- Extracorporeal Membrane Oxygenation Complication, Neonatal Aspiration Pneumonia, Acute Respiratory Failure, Acute Lung Injury
- Trial name
- PETIT (NCT06750536)
- Testing
- MiniLung petite kit combined with the Xenios console
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- Xenios AG
Acute Decompensated Heart Failure, Heart Failure
The Influence of Beta Blocker Therapy on the Hemodynamic Response to Inotrope Infusion in Patients With Acute Decompensated Heart Failure
Purpose: To compare the hemodynamic effects of dobutamine and milrinone in hospitalized patients who are receiving Beta Blocker Participants: Patients who are admitted to the General Cardiology and Heart Failure Services at the…
- Trial name
- NCT01971944
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of North Carolina, Chapel Hill
Acute Heart Failure, Congestive Edema
EMEPIC : Value of a Mobile Team of Cardiologist Using Echocardiography for Managing Patients With Acute Heart Failure
The aim of the study is to compare clinical management of patients with acute decompensation of heart failure, hospitalized in non cardiological ward, with the use of a mobile team including a cardiologist with portable…
- Conditions
- Acute Heart Failure, Congestive Edema, Cardiac Disease
- Trial name
- EMEPIC (NCT00568165)
- Testing
- Mobile team, Standard care
- Where
- France
- Volunteers
- 504 people
- Sponsor
- University Paris 7 - Denis Diderot
Atrial Fibrillation
KONVERT-AF - Relevance of Point in Time for Conversion of Acute Atrial Fibrillation
To investigate if in acute symptomatic atrial fibrillation (AF) the early (>2 hrs but within 12 hrs of the beginning of the arrhythmia) electrical cardioversion leads to a longer recurrence-free interval than the delayed…
- Trial name
- NCT00369330
- Testing
- external electrical cardioversion
- Where
- Germany
- Sponsor
- Atrial Fibrillation Network
Heart Failure
Use of mHealth to Increase Physical Activity for Patients Recently Hospitalized With Acute Heart Failure
The aim of this trial is to determine if a mobile application that promotes physical exercise in the follow-up of patients recently hospitalized with acute heart failure can improve exercise capacity after 6 months and physical…
- Trial name
- mRehab (NCT04848298)
- Testing
- mHealth Intervention
- Where
- Spain
- Volunteers
- 116 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Acute Coronary Syndrome, Venous Thrombosis
Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)
This prospective cohort study will provide information about: Characteristics of Rivaroxaban use in patients who are prescribed Rivaroxaban for the first time compared to patients who are prescribed standard of care for the first…
- Conditions
- Acute Coronary Syndrome, Venous Thrombosis, Pulmonary Embolism, Atrial Fibrillation
- Trial name
- NCT02468102
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Standard of care drugs
- Where
- Sweden
- Volunteers
- 99,999 people
- Sponsor
- Bayer
Acute Kidney Injury
Effect of Cholesterol Level on Postoperative Acute Kidney Injury of Non-cardiac Surgeries
Preoperative serum cholesterol level may influence occurrence of postoperative acute kidney injury of cardiac surgeries. However, the effect of Preoperative serum cholesterol level for non cardiac surgery remains unknown.
- Trial name
- NCT03954353
- Where
- China
- Volunteers
- 78,888 people
- Sponsor
- Peking University First Hospital
ST-Elevation Myocardial Infarction
Colchicine's Efficacy in MI Patients: Comparing PCI and Non-Reperfusion Approaches
This study investigates the effect of Colchicine in preventing heart structure changes following ST-segment elevation myocardial infarction.
- Trial name
- NCT06426537
- Testing
- Colchicine 0.5 MG Oral Tablet
- Where
- Indonesia
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Brawijaya
Myocarditis Acute, Myocardial Inflammation
CMR Evaluation of Myocardial Inflammation Persistence After Acute Myocarditis: Prognostic Relevance
Patients with acute myocarditis (AM) usually experience spontaneous healing, but a considerable percentage of them evolve towards chronic long-term cardiac impairment.
- Trial name
- MIAMI (NCT03525639)
- Testing
- Cardiac Magnetic Resonance
- Where
- 3 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Antonio Esposito
Acute ST Segment Elevation Myocardial Infarction
Safety and Efficacy of Percutaneous Coronary Intervention Combined With Thrombolysis at Different Time
Patients with acute ST-segment elevation myocardial infarction and thrombolysis indications, will be given the recombinant human prourokinase for thrombolysis treatment, and in accordance with the guidelines, will be treated with…
- Trial name
- SEPCIT (NCT03137212)
- Testing
- thrombolysis and PCI of A type, thrombolysis and PCI of B type
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Hospital of Jilin University
Acute Coronary Syndrome, Diabetes Mellitus
Peking and Rotterdam on Mission to Reduce Coronary Artery Disease
The purpose of this study is to explore the effect of 20mg high loading dose of rosuvastatin on recurrent events in patients with established DM who is admitted for an ACS.
- Trial name
- PROMISS (NCT01653119)
- Testing
- Rosuvastatin
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking University Third Hospital
Coronary Artery Disease, Coronary Disease
Sapphire II PRO US Clinical Study
A prospective, open label, multi-center, single arm, observational study designed to evaluate the acute safety and device procedural success of the Sapphire II PRO 1.0 and 1.25 mm PTCA dilatation catheters in subjects with…
- Conditions
- Coronary Artery Disease, Coronary Disease, Myocardial Ischemia, Heart Diseases
- Trial name
- NCT03052530
- Testing
- Sapphire II PRO
- Where
- 4 sites in United States
- Volunteers
- 61 people
- Sponsor
- OrbusNeich
Diabetes Mellitus, Acute Coronary Syndrome
The POST-ACS Study
Individuals with T2DM have a two-fold excess risk of cardiovascular (CV) events compared with their non-diabetic counterparts. Although it is the primary cause of death in T2DM, there is no significant evidence that intensive…
- Conditions
- Diabetes Mellitus, Acute Coronary Syndrome, Coronary Artery Disease
- Trial name
- NCT05322200
- Testing
- A computerized tomography (CT) coronary angiogram, Vicorder (Skidmore medical, UK), Blood tests for inflammation and oxidative stress markers
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- Swansea Bay University Health Board
Heart Failure
Hospitalization at Home of Elderly Patients With Heart Failure
Aim of the study was to evaluate the efficacy of hospital-at-home treatment compared with inpatient care in selected elderly patients with acute exacerbation of chronic heart failure (CHF).
- Trial name
- NCT00623571
- Testing
- Treatment of elderly patients in a GMW, Treatment of elderly patients in GHHS
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Coronary Artery Disease, Calcification
Intravascular Lithotripsy for Acute Stent Under-expansion in Calcified Coronary Lesions
Percutaneous coronary intervention (PCI) is the standard treatment for patients with coronary artery disease who have an indication for surgery.
- Trial name
- NCT06669195
- Testing
- Intravascular lithotripsy group, high-pressure balloon group
- Volunteers
- 40 people
- Sponsor
- Xuzhou Third People's Hospital
Acute Coronary Syndromes
Effect of rHDL on Atherosclerosis - Safety and Efficacy: THE ERASE TRIAL
Currently available therapies to treat Acute Coronary Syndromes(ACS) have several limitations including; the relatively long treatment duration required before apparent significant benefit; the inability to achieve reversal of…
- Trial name
- NCT00225719
- Testing
- rHDL
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- CSL Limited
Coronary Heart Disease
China PEACE-Prospective AMI Study
Coronary heart disease (CHD) and heart attacks pose a serious health risk to men and women, however little information is available about how evidence-based therapies are incorporated appropriately into routine clinical practice…
- Trial name
- NCT01624909
- Where
- China
- Volunteers
- 4,286 people
- Sponsor
- China National Center for Cardiovascular Diseases
Acute Coronary Syndrome
Rehabilitation Exercise With MObile Technology and Education After Acute Coronary Syndrome
Despite a clear indication of grade Ia, cardiac rehabilitation (CR) is dramatically underutilized after acute coronary syndrome with less than 30% of patients addressed in France.
- Trial name
- REMOTE-ACS (NCT05385341)
- Testing
- Telerehabilitation (Tele RCV), Rehabilitation (RCV)
- Sponsor
- University Hospital, Toulouse
Non ST Elevation Myocardial Infarction, Unstable Angina
Conservative Non-Invasive Versus Routine Invasive Management in Coronary Artery Bypass Surgery Patients with Non ST Elevation Elevation Acute Coronary Syndrome
Background: Most coronary artery bypass grafts (CABG) are diseased or blocked within 10 years of surgery meaning CABG survivors have an ever increasing risk of recurrent angina, heart attack and death.
- Trial name
- CABG-ACS (NCT01895751)
- Testing
- Invasive management
- Where
- 5 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- NHS National Waiting Times Centre Board
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