Clinical trials: Acute Exacerbation COPD
COPD Exacerbation Acute
The Use of Medical Devices to Monitor Chronic Obstructive Pulmonary Disease Patients Study BREATH-TRACHER 1
The proposed study will explore whether remote monitoring of a COPD patient can be undertaken using a wearable medical device.
- Trial name
- BREATH-TRACHER (NCT06419036)
- Testing
- Pneumowave DC
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Strathclyde
Chronic Obstructive Pulmonary Disease
Exhaled Breath Condensate (EBC) Assessment in Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)
This study aimed to assess airway inflammation in patients during the course of acute exacerbations of chronic obstructive pulmonary disease (AECOPD) by serial analyses of their exhaled breath condensates (EBC).
- Trial name
- NCT00448500
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
COPD Exacerbation
TNF-alpha Antagonists for AECOPD: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial
The purpose of this study is to determine whether treatment with antibiotics plus a TNFalpha antagonist will provide more effective treatment for acute COPD exacerbation compared to the current standard treatment of antibiotics…
- Trial name
- NCT00789997
- Testing
- Prednisone, Etanercept, levofloxacin
- Volunteers
- 81 people
- Sponsor
- Ottawa Hospital Research Institute
Congestive Heart Failure, Copd
A Mobile Integrated Health Intervention to Manage Congestive Health Failure and Chronic Obstructive Pulmonary Disease
Episodic and disjointed medical care for older, community-dwelling adults with chronic obstructive pulmonary disease (COPD) and congestive heart failure (CHF) leave them vulnerable to adverse events such as worsening disease…
- Trial name
- NCT05540158
- Testing
- Mobile Integrated Health Intervention
- Sponsor
- University of Massachusetts, Worcester
Chronic Obstructive Pulmonary Disease, COPD Exacerbation
Respiratory Support in Chronic Obstructive Pulmonary Disease (COPD) Patients
The hypothesis of this study is that any of 3 modalities of home non- invasive ventilation (NIV) compared to 'no NIV' (=hospital NIV) will reduce re-admission to hospital or death in COPD patients who remain persistently…
- Trial name
- NCT03890224
- Testing
- home ventilators
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Clinact
Pulmonary Disease, Chronic Obstructive, Respiratory Tract Diseases
Do the SPPB and 4-metre Gait Speed Predict Hospital Readmission in Patients Hospitalised for Acute Exacerbation if COPD?
This study aims to evaluate simple tests of physical function in hospitalised patients with chronic obstructive pulmonary disease (COPD) and to assess whether they can predict future hospital readmission.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Respiratory Tract Diseases, Lung Diseases, Lung Diseases, Obstructive
- Trial name
- NCT01507415
- Where
- 2 sites in United Kingdom
- Volunteers
- 226 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Falls Injury, Falls
Potential of Interface Care Models to Deliver More Appropriate Care to Patients With Acute Medical Illness
Every country in the world is experiencing growth in both the size and the proportion of older persons. As a result of the changes, the profile and needs of people with medical illnesses have evolved.
- Conditions
- Falls Injury, Falls, Hospitalization in Acute Care, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT07536035
- Where
- Singapore
- Volunteers
- 220 people
- Sponsor
- National University Hospital, Singapore
Chronic Obstructive Pulmonary Disease Exacerbation
Neutrophil to Lymphocyte Ratio in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) stands as one of the leading causes of mortality worldwide. Acute exacerbations of COPD (AECOPD) lead to rapid respiratory function decline and worsened disease status.
- Trial name
- NCT07125352
- Testing
- neutrophil lymphocyte ratio in COPD patients
- Where
- Egypt
- Volunteers
- 190 people
- Sponsor
- Ain Shams University
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Effects of High-intensity Noninvasive Positive Pressure Ventilation in AECOPD
This study aims to investigate the effects of high-intensity noninvasive positive pressure ventilation (NPPV), as compared with low-intensity NPPV, on hypercapnia, consciousness, inspiratory muscle effort, dyspnea, NPPV…
- Trial name
- NCT04044625
- Testing
- High-intensity NPPV, Low-intensity NPPV
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Beijing Chao Yang Hospital
Acute Exacerbation of COPD
High Flow Nasal Oxygen for Exacerbation COPD
In this pilot study the feasibility of performing a larger trial to study the non-inferiority of High Flow Nasal Oxygen compared to non-invasive ventilation in patients with acute acidotic hypercapnic exacerbation of COPD wil be…
- Trial name
- HiCAP (NCT06084117)
- Testing
- HFNO, NIV
- Where
- 4 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Franciscus Gasthuis
Chronic Obstructive Pulmonary Disease
Predict&Prevent: Use of a Personalised Early Warning Decision Support System to Predict and Prevent Acute Exacerbations of COPD
COPD is a common complex disease with debilitating breathlessness; mortality and reduced quality of life, accelerated by frequent lung attacks (exacerbations).
- Trial name
- NCT04136418
- Testing
- COPDPredict mobile App, Usual care
- Where
- United Kingdom
- Volunteers
- 384 people
- Sponsor
- University of Birmingham