Clinical trials: Acute Fracture
Hip Fractures, Intraoperative Hypotension
Peri-operative Vasopressor Support in Patients Operated for an Acute Hip Fracture (AHF)
The incidence of hypotension perioperatively during operation of an acute hip fracture is unknown. As a surrogate factor the usage of vasopressor support is more adequate as the registration of vasopressor drugs are many times…
- Trial name
- NCT03497949
- Where
- Sweden
- Volunteers
- 997 people
- Sponsor
- Sahlgrenska University Hospital
Acute Pain
Efficacy of Gabapentin vs. Placebo for Adjuvant Pain Control Following Acute Rib Fractures
A Multi-center, Randomized Controlled Trial of the Efficacy of Gabapentin vs. Placebo for Adjutant Pain Control Following Acute Rib Fractures.
- Trial name
- NCT02856750
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Clavicle Fracture, Fractures
Conservative Treatment Versus Operative Plate Fixation for Acute, Displaced Fractures of the Distal Clavicle
This is a multicentre randomized clinical trial prospectively comparing operative treatment versus conservative (nonoperative) care in the management of displaced distal (Type II) clavicle fractures.
- Trial name
- NCT00872105
- Testing
- Non-operative Treatment, Operative Treatment
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- Unity Health Toronto
Pain, Acute
SOFT Block Versus Spinal Anesthesia in Patientsusing Ilizarov External Fixator
Peripheral nerve block is an ideal choice for lower limb surgery because of the peripheral site of the surgical procedure and the ability to block pain pathways at multiple levels.
- Trial name
- NCT03450798
- Testing
- SOFT block group, spinal anesthesia group
- Where
- Egypt
- Volunteers
- 107 people
- Sponsor
- Ain Shams University
Hip Fractures
Effects of Music on Acute Postoperative Pain Intensity and Mobility After Fragility Hip Fracture
Music has been proven to be beneficial in postoperative care by reducing pain. The effects of music listening to reduce pain postoperatively are well studied among cases undergoing elective orthopaedic surgery.
- Trial name
- NCT06277102
- Testing
- music listening
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Hospital Authority, Hong Kong
Rib Fractures, Pain, Acute
Erector Spinae Plane (ESP) Versus Paravertebral Nerve (PVB) Blockade for Acute Unilateral Rib Fracture Pain
Continuous paravertebral analgesia and erector spinae plane blockade (ESP) are accepted techniques at University of Pittsburgh Medical Center (UPMC) for the management of thoracic pain following surgery and trauma.
- Conditions
- Rib Fractures, Pain, Acute, Thoracic Injuries, Neuropathic Pain
- Trial name
- NCT03540095
- Testing
- Erector Spinae Plane Block, Paravertebral Nerve Block
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Pittsburgh
Wrist Injuries, Wrist Fracture
Splinted Wrist Study
Randomized clinical trial comparing SAM aluminium splint vs pain relief as usual in patients seeking emergency department care for suspected wrist fractures.
- Conditions
- Wrist Injuries, Wrist Fracture, Pain, Acute
- Trial name
- NCT07553000
- Testing
- SAM splint
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane
SPINAL Fracture
Comparative Study of Balloon Kyphoplasty and Conservative Treatment
This study will compare two treatments in acute stable traumatic vertebral fractures (types A1, A2 and A3.1 in MAGERL Classification). The two treatments are the followings: 1.
- Trial name
- TRAUMAA1-2-3 (NCT00749242)
- Testing
- orthopedic brace, balloon kyphoplasty
- Where
- France
- Volunteers
- 41 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rib Fractures, Serratus Anterior Plane Block
Comparison of the Analgesic Efficacy of Serratus Anterior Plane Block and Intercostal Block
More than 50% of patients presenting with chest trauma experience rib fractures and these rib fractures are associated with significant morbidity, mortality, and long-term disability.
- Conditions
- Rib Fractures, Serratus Anterior Plane Block, Erector Spinae Plane Block, Acute Pain
- Trial name
- NCT05160155
- Testing
- Serratus Anterior Plane Block, Intercostal Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Back Pain
Tapentadol IR vs Oxycodone IR vs Placebo in Acute Pain From Vertebral Compression Fracture Associated With Osteoporosis
The purpose of this study is to determine the effectiveness and safety of tapentadol immediate release (IR) as compared with placebo and oxycodone IR in patients with acute pain caused by vertebral compression fractures (VCF)…
- Trial name
- NCT00771758
- Testing
- oxycodone IR, tapentadol IR
- Where
- 37 sites in United States
- Volunteers
- 108 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Hand, Wrist
Percutaneous Screw Fixation for Acute Scaphoid Fractures Through K-wire-assisted Reduction and Maintenance
The scaphoid is the most common fractured carpal bone in active adults, accounting for up to 80% of all carpal fractures. The optimum treatment approach of the acute scaphoid fractures is under discussion.
- Conditions
- Hand, Wrist, Wounds and Injuries
- Trial name
- NCT04482868
- Testing
- Percutaneous screw fixation through K-wire-assisted reduction and maintenance
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hebei Medical University
Hip Fracture, Analgesia
Ultrasound Percapsular Nerve Group Block VS Fascia Iliaca Block for Hip Fracture
Spinal anesthesia (SA) is a widely accepted anesthetic technique for hip fracture repair among elderly. Positioning for SA can be extremely painful. Effective management of pain is important for these patients comfort.
- Conditions
- Hip Fracture, Analgesia, Acute Pain
- Trial name
- NCT04285333
- Testing
- fascia iliaca block, percapsular nerve group block
- Where
- Tunisia
- Volunteers
- 88 people
- Sponsor
- University Tunis El Manar
Acute, Displaced Midshaft Clavicle Fractures
Treatment of Displaced, Midshaft Clavicle Fractures. Sling or Plate?
Clavicle fractures are frequent and represent somewhere between 5 and 10% of all fractures seen in orthopedics. There is no consensus concerning the best treatment of acute, displaced, midshaft clavicle fractures.
- Trial name
- NCT01483482
- Testing
- Conservative Treatment, Surgical treatment
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Hvidovre University Hospital
Vertebral Fracture, Osteoporotic Fractures
CCEF in the Treatment of Acute VFFs: Randomized Controlled Trial
in recent years the search for therapeutic protocols that could enhance the VFFs healing, thus reducing bed rest-related complications and improving the quality of life of osteoporotic patients.
- Trial name
- NCT05803681
- Testing
- Capacitive Coupled Electric Fields (CCEF), Calssic clinical protocol
- Volunteers
- 70 people
- Sponsor
- University of Bari Aldo Moro
Pain
A Pilot Study of TRV130 for the Treatment of Fracture Pain
The primary objective is to evaluate the analgesic efficacy of TRV130 for moderate to severe acute pain in patients presenting to the emergency department (ED) with a suspected/known, unilateral, closed long bone fracture.
- Trial name
- NCT02520297
- Testing
- TRV130
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Trevena Inc.
Post-Operative Delirium, Hip Fracture
Post-operative Haloperidol Versus Placebo for Prevention of Post-operative Delirium After Acute Hip Surgery
In this study the investigators want to determine if treatment with haloperidol direct post-operatively after acute hip surgery in high risk patients protects against developing a post-operative delirium.
- Trial name
- NCT00250237
- Testing
- Haloperidol
- Where
- Netherlands
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Bronovo Hospital
Osteoporotic Fractures
Vertebroplasty Compared With a Sham-procedure for Painful Acute Osteoporotic Vertebral Fractures
The main purpose of this study: to determine whether vertebroplasty has a pain palliating effect superior to a sham-procedure for acute painful osteoporotic vertebral fractures of the thoracic and lumbar spine.
- Trial name
- VOPE (NCT01537770)
- Testing
- Percutaneous vertebroplasty, Lidocaine injection
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- Spine Centre of Southern Denmark
Hypotension, Hip Fractures
Acute Hip Fracture and Spinal Anaesthesia Injection Time
The systemic effects of spinal anesthesia is not fully known. Our aim of this study is to assess whether there is a difference in hemodynamic effects if the spinal dose is given fast (15s) or slow (90s) in elderly patients with…
- Conditions
- Hypotension, Hip Fractures, Anesthesia
- Trial name
- NCT05564741
- Testing
- Norepinephrine 1 MG/ML
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Sahlgrenska University Hospital
Distal Femur Fracture
Far Cortical Locking Versus Standard Constructs for Distal Femur Fractures
To determine if Far Cortical Locking screws increase fracture healing rates at 3 months in Closed Distal Femur Fractures in adults when compared to Standard screw constructs.
- Trial name
- FCL (NCT01766648)
- Testing
- Far Cortical locking screw fixation, Standard screw fixation
- Where
- Canada
- Volunteers
- 167 people
- Sponsor
- University of British Columbia
Ankle Fractures, Intra-Articular Fractures
Prevention of Posttraumatic Osteoarthritis After Acute Intraarticular Fractures
Intra-articular fracture is a very common fracture. The only method to treat these fractures is surgery with plate and screws followed by rehabilitation.
- Conditions
- Ankle Fractures, Intra-Articular Fractures, Osteoarthritis
- Trial name
- NCT03769909
- Where
- Denmark
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark