Clinical trials: Acute Gastroenteritis
Acute Appendicitis
The Performance of the APPY1 Test in the Evaluation of Possible Acute Appendicitis
This study will consist of a brief interaction with the subject or parent or guardian to obtain consent, collect a blood sample, medical history, and physical examination of those who meet the inclusion criteria.
- Trial name
- APPY1 (NCT01652170)
- Where
- 29 sites in United States
- Volunteers
- 2,201 people
- Sponsor
- Venaxis, Inc.
Gastritis, Acute Gastritis
Phase 4 Study of Sto M Tab. in Acute or Chronic Gastritis
This Phase 4, multicenter, randomized, double-blind, active-controlled, non-inferiority study aims to evaluate the non-inferiority of Stoem Tab. compared to Stillen Tab.
- Conditions
- Gastritis, Acute Gastritis, Chronic Gastritis
- Trial name
- NCT07631065
- Testing
- Stillen Tab., Sto M Tab.
- Volunteers
- 470 people
- Sponsor
- Mather's Pharm. Co., Ltd.
Acute Gastroenteritis, Norwalk Virus Infection
Norwalk Vaccine Study
The purpose of this study was to evaluate the efficacy of the Norwalk virus-like particle (VLP) vaccine as determined by the illness rate of viral acute gastroenteritis (AGE) during the inpatient stay.
- Trial name
- NCT00973284
- Testing
- Norwalk VLP vaccine, mannitol and sucrose, Norwalk virus
- Where
- 3 sites in United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Takeda
Acute Gastroenteritis
A Multi-Site Clinical Evaluation of the ARIES Norovirus Assay
The ARIES Norovirus Assay is a real-time PCR based qualitative in vitro diagnostic test for the direct detection of Norovirus GI/GII RNA from stool specimens obtained from symptomatic patients.
- Trial name
- NCT02092259
- Where
- 5 sites in United States
- Volunteers
- 500 people
- Sponsor
- Luminex Corporation
Ulcerative Colitis
User Surveillance in Ulcerative Colitis
The aim of the non-interventional study is to document the daily doses in acute and remission therapy, the frequence of doses (1, 2, 3 or 4 times daily), when rectal dosage forms are added and, when and how long steroids are…
- Trial name
- CARE (NCT01363453)
- Where
- 105 sites in Germany
- Volunteers
- 500 people
- Sponsor
- Ferring Pharmaceuticals
Diverticulitis
Asacol Acute Diverticulitis(DIVA)Study
The purpose of this study is to determine whether Asacol® 2.4 g/day (400 mg Mesalamine) is safe and effective in the treatment of diverticulitis.
- Trial name
- NCT00554099
- Testing
- Mesalamine, Probiotic, Dietary Advice
- Where
- 36 sites in United States
- Volunteers
- 117 people
- Sponsor
- Warner Chilcott
Gastroenteritis, Gastritis
BEKINDA (Ondansetron 24 mg Bimodal Release Tablets) for Vomiting Due to Presumed Acute Gastroenteritis or Gastritis
Randomized, Placebo-Controlled, Phase 3 Trial of RHB-102 (BEKINDA) (Ondansetron 24 mg Bimodal Release Tablets) for Acute Gastroenteritis.
- Trial name
- GUARD (NCT02246439)
- Testing
- RHB-102
- Where
- 26 sites in United States
- Volunteers
- 330 people
- Sponsor
- RedHill Biopharma Limited
Ulcerative Colitis
Efficacy and Safety of Asacol™ 4.8 g/Day (800 mg Tablets) for the Treatment of Active Ulcerative Colitis
The primary objective of the study is to determine the efficacy of Asacol™ 4.8 g/day (800 mg tablets) to induce clinical and endoscopic remission after 6 weeks of treatment compared to placebo in subjects with active ulcerative…
- Trial name
- NCT01059344
- Testing
- Mesalamin
- Where
- 31 sites in Belarus, India and 2 more
- Volunteers
- 281 people
- Sponsor
- Tillotts Pharma AG
Crohn's Disease
High Dose Oral 4-Aminosalicylic Acid (PASER®) to Control Acute Flares of Mild to Moderate Crohn's Disease
The purpose of this 4 week study is to determine whether PASER®, an approved delayed-release oral formulation of 4-aminosalicylic acid, in doses of 4 grams three times daily for 2 weeks followed by 4 grams twice daily for 2…
- Trial name
- NCT00417690
- Testing
- 4-Aminosalicylic acid
- Where
- 5 sites in United States, Israel
- Volunteers
- 54 people
- Sponsor
- Jacobus Pharmaceutical
Diverticulitis
Rifaximin Delayed Release for the Prevention of Recurrent Acute Diverticulitis and Diverticular Complications.
Colonic microbiota changes may play a key role in the pathogenesis of acute diverticulitis. A previous proof-of-concept study suggests that rifaximin, a low-absorbable oral antibiotic, may be beneficial for prevention of acute…
- Trial name
- ROAD (NCT03469050)
- Testing
- Rifaximin delayed released 400mg Tablet
- Where
- 64 sites in France, Germany and 4 more
- Volunteers
- 193 people
- Sponsor
- Alfasigma S.p.A.
Hematologic Malignancies
Efficacy Study of a TXA127 to Reduce Acute Graft-vs-Host Disease in Subjects Undergoing Double Umbilical Cord Blood Transplantation
The purpose of this study is to evaluate the efficacy of TXA127 to reduce the incidence (Grade II-IV) of acute Graft-vs.-Host Disease (aGVHD) in adult subjects undergoing double umbilical cord blood transplantation (UCBT).
- Trial name
- NCT01882374
- Testing
- TXA127
- Where
- United States
- Sponsor
- Tarix Pharmaceuticals
Appendicitis Acute, Appendicitis
Clinical Trial for a Outpatient Clinical Management of Urgent Laparoscopic Appendectomy
The aim of this study is to evaluate the safety and efficacy of outpatient management of uncomplicated acute appendicitis. For this purpose, a randomized clinical trial was designed.
- Trial name
- ASI (NCT05401188)
- Testing
- Outpatient, hospitalization
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- HJ23
Acute Appendicitis, Appendicitis Perforated
Clinical Trial for a Outpatient Clinical Management for Complicated Acute Appendicitis
The aim of this study is to evaluate the safety and efficacy of outpatient management of complicated acute appendicitis. For this purpose, a randomized clinical trial was designed.
- Conditions
- Acute Appendicitis, Appendicitis Perforated, Appendicitis Suppurative
- Trial name
- ASI2 (NCT06059365)
- Testing
- Hospitalization, Outpatient
- Volunteers
- 92 people
- Sponsor
- HJ23
Hospitalized Cases of Angioneurotic Oedema, Pneumonia
Drug Utilization and Safety Events Among Children Using Esomeprazole, Other Proton Pump Inhibitors or H2-receptor Antagonists
The purpose of this study is 1. To describe patient characteristics and drug usage among children that are prescribed esomeprazole for the first time and to compare them with patients who are prescribed other proton pump…
- Conditions
- Hospitalized Cases of Angioneurotic Oedema, Pneumonia, Gastroenteritis, Failure to Thrive
- Trial name
- NCT01338363
- Where
- Netherlands
- Volunteers
- 23,470 people
- Sponsor
- AstraZeneca
Proctitis
Budesonide vs. Mesalazine vs. Budesonide/Mesalazine Suppository Combination Therapy in Acute Ulcerative Proctitis
The purpose of this study is to investigate the efficacy and safety of budesonide suppository for the treatment of acute ulcerative proctitis.
- Trial name
- NCT01966783
- Testing
- Budesonide 2 mg suppository, Budesonide 4 mg suppository, Mesalazine 1 g suppository
- Where
- 2 sites in Germany
- Volunteers
- 320 people
- Sponsor
- Dr. Falk Pharma GmbH
Rotaviral Gastroenteritis
Study to Estimate the Disease Burden of Acute Rotavirus Gastroenteritis in Children < 5 Years in United Arab Emirates
The purpose of this study is to estimate the disease burden and epidemiology of rotavirus gastroenteritis in children less than 5 years of age, in United Arab Emirates.
- Trial name
- NCT01201252
- Testing
- Stool sampling
- Where
- 3 sites in United Arab Emirates
- Volunteers
- 717 people
- Sponsor
- GlaxoSmithKline
Hematologic Malignancies
Efficacy Study of a TXA127 to Reduce Graft-vs-Host Disease in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation
The purpose of this study is to evaluate the efficacy of TXA127 to reduce the incidence (Grade II-IV) of acute Graft-vs.-Host Disease (aGVHD) in adult subjects undergoing allogeneic peripheral blood stem cell transplantation…
- Trial name
- NCT01882387
- Testing
- TXA127
- Where
- 2 sites in United States
- Sponsor
- Tarix Pharmaceuticals
Appendicitis Acute, Appendicitis
Safety & Feasibility of PERIsign System in Demonstrating Involuntary Muscle Defense as a Sign of Peritonitis in Subjects With Appendicitis
This will be an explorative, proof-of-principle, open, multi-center investigation. The investigation aims to investigate the safety of the PERIsign system and the ability of physicians to differentiate between healthy individuals…
- Conditions
- Appendicitis Acute, Appendicitis, Abdominal Pain, Peritonitis
- Trial name
- PeriSaFe01 (NCT06296953)
- Testing
- PERIsign examination
- Where
- 2 sites in Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- STB INN AB
Enteritis
A Dose Ranging Study of Delayed Release Beclomethasone for Prevention of Acute Enteritis in Patients With Rectal Cancer
The purpose of this study is to evaluate the safety and preliminary efficacy of four doses of SGX201 in subjects with rectal cancer treated with concurrent radiation and chemotherapy.
- Trial name
- NCT01073384
- Testing
- SGX201 (delayed release beclomethasone 17,21-dipropionate)
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Soligenix
Acute Appendicitis
Retrospective Acute Care Appendectomy Study
The purpose of this retrospective study is to compare perioperative data for subjects who have undergone an emergent or urgent robotic-assisted or laparoscopic appendectomy for acute appendicitis.
- Trial name
- NCT06624215
- Testing
- Appendectomy
- Where
- 3 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Intuitive Surgical