Clinical trials: Acute Gout Flare
Gouty Arthritis
Oral Huzhang Granules for Acute Gouty Arthritis
We designed this study as a double-blind, randomized, controlled clinical trial. The aim of the study is to evaluate the clinical efficacy, safety and control of recurrence rate of acute gouty arthritis
- Trial name
- NCT04462666
- Testing
- Huzhang granule, Etoricoxib
- Volunteers
- 267 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Gout
Topical Application to Relieve Gout: Efficacy Trial & Safety (TARGETS)
This overall goal of this trial will be to demonstrate that DYV700 is safe and effective as a treatment for acute gout flares.
- Trial name
- TARGETS (NCT04130204)
- Testing
- DYV700, Colchicine 0.6 mg
- Where
- United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Dyve Biosciences, Inc.
Acute Gout
Prednisolone Versus Colchicine for Acute Gout in Primary Care
Gout is the most common form of rheumatic disease in which monosodium urate crystals are deposited in the joints followed by acute inflammatory reactions.
- Trial name
- COPAGO (NCT05698680)
- Testing
- Prednisolone 30 mg Tablet, Colchicine 0.5 mg Oral Tablet
- Where
- 65 sites in Germany
- Volunteers
- 186 people
- Sponsor
- University Medicine Greifswald
Acute Gout
A Study of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection in Chinese Participants With Acute Gout
The purpose of this study is to determine the efficacy and safety of recombinant anti-IL-1β humanized monoclonal antibody injection in Chinese participants with acute gout.
- Trial name
- NCT06169891
- Testing
- Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection 200 mg, Compound Betamethasone Injection
- Volunteers
- 500 people
- Sponsor
- Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
Acute Gouty Arthritis
The Clinical Study on Treating Acute Gouty Arthritis Using Both Internal and External Therapy of Tonifying Spleen and Descending Turbid
This research is based on spleen trapped by dampness and turbid which is the pathogenesis of gouty arthritis.It uses effective prescription of Endocrinology of Dongzhimen Hospital.In this study, the investigators use multi-center…
- Trial name
- NCT02545777
- Testing
- diclofenac sodium enteric-coated, Oral medicine of tonifying spleen and descending turbid, Steeping and washing medicine of descending turbid and clearing heat
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Beijing University of Chinese Medicine
Gouty Arthritis
A Study to Evaluate Efficacy and Safety of Qingzhu Granules in the Treatment of Acute Gouty Arthritis
This study will evaluate the efficacy and safety of Qingzhu Granules in the treatment of Acute Gouty Arthritis ( Damp heat pattern)
- Trial name
- NCT06068478
- Testing
- Qingzhu Granules
- Where
- 29 sites in China
- Volunteers
- 472 people
- Sponsor
- Tasly Pharmaceutical Group Co., Ltd
Gout Flare
The Effects of Limb Elevation During Gout Flare Episodes
The goal of this open-label randomized controlled trial is to explore the benefit of limb elevation in inpatient gout flare episodes, compared with standard treatment The main questions are; Is limb elevation able to reduce pain…
- Trial name
- NCT06207045
- Testing
- limb elevation
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Thammasat University
Infection, Heart Failure
Hospital-Level Care at Home for Acutely Ill Adults
The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be…
- Conditions
- Infection, Heart Failure, COPD, Asthma
- Trial name
- NCT03203759
- Testing
- Home hospitalization, Traditional inpatient hospitalization
- Where
- 2 sites in United States
- Volunteers
- 91 people
- Sponsor
- Brigham and Women's Hospital
Acute Gout Flare, Gout Attack
Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare
The purpose of this trial is to investigate the efficacy and safety of dapansutrile (OLT1177®) tablets in subjects with an acute gout flare.
- Conditions
- Acute Gout Flare, Gout Attack, Gout Flare, Gouty Arthritis
- Trial name
- NCT05658575
- Testing
- Dapansutrile
- Where
- 40 sites in United States, France and 3 more
- Volunteers
- 300 people
- Sponsor
- Olatec Therapeutics, Inc.
Pharmacokinetics
Pharmacokinetic Study of an Acute Gout Regimen
This study aims to characterize the pharmacokinetic profile of colchicine after a regimen of 1.8 mg over two hours. A secondary goal is to evaluate the safety and tolerability of this regimen in healthy volunteers.
- Trial name
- NCT01017042
- Testing
- colchicine tablets
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Mutual Pharmaceutical Company, Inc.
Acute Gout Arthritis, Acupuncture
Immediate Analgesic Effects of Cheek Acupuncture for Acute Gouty Arthritis
The goal of this clinical trial is to evaluate the immediate analgesic effect and patients' evaluation of the treatment of cheek acupuncture in patients with acute gouty arthritis.
- Conditions
- Acute Gout Arthritis, Acupuncture, Acute Pain
- Trial name
- CAAGA (NCT06001112)
- Testing
- cheek acupuncture, Etoricoxib
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Gout; Hyperuricemia, Gout Flare
Developing A Gout Action Plan in Primary Care Setting in Singapore
The goal of this clinical trial is to develop a gout action plan in primary care setting in Singapore among adult patients with gout, and to learn if the gout action plan can improve gout control.
- Conditions
- Gout; Hyperuricemia, Gout Flare, Gout Chronic
- Trial name
- NCT07061587
- Testing
- Gout action plan
- Where
- Singapore
- Volunteers
- 72 people
- Sponsor
- SingHealth Polyclinics
Gout Arthritis, Gout Flare
Purified Cortrophin® Gel Efficacy and Safety Study of 2 Dose Levels in Patients With Acute Gout Flares
This is a randomized, multicenter, double-blind, single administration study to investigate the efficacy and safety of 2 dosing regimens of Purified Cortrophin® Gel in the treatment of an acute gouty arthritis flare.
- Conditions
- Gout Arthritis, Gout Flare, Gout
- Trial name
- NCT07346079
- Testing
- Purified Cortophin Gel, 40 U, Purified Cortophin Gel 80 U
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Massachusetts General Hospital
Gout
Bucillamine for the Treatment of Acute Gout Flare in Subjects With Moderate to Severe Gout
A Phase IIA, open-label, multicenter, active-controlled, parallel-group clinical trial designed to evaluate the safety and efficacy of two doses of Bucillamine compared with low-dose Colchicine in the treatment of patients with…
- Trial name
- NCT02330796
- Testing
- Bucillamine, Colchicine
- Where
- 3 sites in United States
- Volunteers
- 66 people
- Sponsor
- Revive Therapeutics, Ltd.
Gout Flare
Relation Between Blood Concentration of Colchicine and Response to Colchicine Treatment in Gout Flare
Gout, secondary to sodium urate crystal deposition, is responsible of recurrent inflammatory painful flares. Efficacy of colchicine which is the first line drug for the treatment and prophylaxis of gout flare varies and only half…
- Trial name
- COMpARE (NCT03933007)
- Testing
- Colchicine,, midazolam,, fexofenadine
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gout, Chronic Kidney Diseases
Anakinra vs. Steroids for the Treatment of Gout Attacks in Patients With Renal Disease (ASGARD): A Feasibility Study
The aim of this study is to determine the feasibility of running a phase III double-blind, double-dummy randomised controlled trial comparing Depo-Medrone 120mg intramuscular injection vs.
- Trial name
- ASGARD (NCT02578394)
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mid and South Essex NHS Foundation Trust
Gout
Allopurinol in Acute Gout
The objectives of the present study are to determine if starting treatement of hyperuricemia with allopurinol during an acute gout crises has an impact on the duration or the severity of the crises
- Trial name
- NCT01775098
- Testing
- allopurinol
- Sponsor
- Université de Sherbrooke
Acute Gout
Clinical Study of Genakumab for Injection in Patients With Acute Gout
To evaluate the safety and tolerability of single subcutaneous injection of Genakumab for Injection in patients with acute gout
- Trial name
- NCT05328531
- Testing
- Genakumab for Injection
- Where
- China
- Volunteers
- 121 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Acute Gout
Efficacy and Safety of HuZhen Capsule for Treatment of Patients With Acute Gout
This study is a multi-center, double-blind, randomized, parallel controlled trial. Patients with acute gout will be enrolled and randomly allocated into 2 groups: HuZhen capsule treatment group and Placebo control group.
- Trial name
- NCT02674776
- Testing
- HuZhen Capsule
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Quan Jiang
Gout Arthritis, Gout Attack
Efficacy Anda Safety of Etoricoxib With Betamethasone for the Treatment of Acute Gout Arthritis
Phase III longitudinal, multicenter, randomized, double-blind clinical trial. The aim of this study is to evaluate the efficacy and safety of the Fixed-Dose Combination of Etoricoxib/Betamethasone Versus Etoricoxib in Patients…
- Trial name
- NCT06863701
- Testing
- Etoricoxib + Betamethasone fixed dose, Etoricoxib fixed dose
- Where
- Mexico
- Volunteers
- 72 people
- Sponsor
- Laboratorios Silanes S.A. de C.V.