Clinical trials: Acute Hip Fractures
Hip Fractures, Blood Loss
Early Administration Of Tranexamic Acid And Acute Blood Loss In Patients With Hip Fractures
The study is a prospective, randomized, double blinded, placebo controlled trial that aims to investigate the hypothesis that early administration of tranexamic acid (TXA) following diagnosis of hip fracture will lower pre and…
- Trial name
- NCT05518279
- Testing
- Tranexamic Acid Pill
- Sponsor
- Henry Ford Health System
Post-Operative Delirium, Hip Fracture
Post-operative Haloperidol Versus Placebo for Prevention of Post-operative Delirium After Acute Hip Surgery
In this study the investigators want to determine if treatment with haloperidol direct post-operatively after acute hip surgery in high risk patients protects against developing a post-operative delirium.
- Trial name
- NCT00250237
- Testing
- Haloperidol
- Where
- Netherlands
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Bronovo Hospital
Hip Fractures
Acute Hip Fracture Study in Patients 65 Years or Greater
This is a randomized, double-blind, parallel group, placebo-controlled, multicenter study to investigate the safety, tolerability, and efficacy of VK5211 after 12 weeks of treatment.
- Trial name
- NCT02578095
- Testing
- VK5211
- Where
- 21 sites in United States, Hungary and 2 more
- Volunteers
- 108 people
- Sponsor
- Viking Therapeutics, Inc.
Hip Fractures, Pain, Acute
Pericapsular Nerve Group Block for Hip Fractures
This will be a feasibility study to see if it feasible to perform the Pericapsular Nerve Group Block for hip fractures in the Emergency Department.
- Trial name
- NCT04882384
- Testing
- Pericapsular Nerve Group Block
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jacobi Medical Center
Acute Hip Fractures
Tranexamic Acid Use in Acute Hip Fractures
BACKGROUND: Tranexamic acid (TXA) has been used widely for the reduction of post operative blood loss for various orthopaedic procedures including but not limited to total hip arthroplasty and total knee arthroplasty.
- Trial name
- NCT02947529
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Carilion Clinic
Postoperative Pain, Hip Fracture
Transcutaneous Nerve Stimulation for Post-operative Acute and Chronic Pain
Aim of the study to assess the efficacy of two modes of transcutaneous electrical nerve stimulation (TENS) on relief of postoperative acute pain after hip fracture surgery.
- Trial name
- NCT02642796
- Testing
- transcutaneous electric nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Mustafa Kemal University
Hip Fractures, Hypotension on Induction
Can Continuous Non-invasive Monitoring Improve Stability of Intraoperative Blood Pressure - A Feasibility Study.
Background During anaesthesia for repair of a broken hip, many patients experience low blood pressure. There have been many studies showing that patients who experience low blood pressure during anaesthesia are at increased risk…
- Conditions
- Hip Fractures, Hypotension on Induction, Intraoperative Hypotension, Acute Kidney Injury
- Trial name
- iSTABILISE (NCT04051073)
- Testing
- Continuous non-invasive blood pressure monitoring
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Alzheimers Disease, Inflammation
Alzheimers Disease and Neuromarkers in Patients With Acute Hip Fractures
The investigators explore the presence of AD factors beta-amyloid and tau in CSF and plasma to verify AD diagnosis in patients with acute hip fracture. Clinical dementia test is performed prior to operation.
- Conditions
- Alzheimers Disease, Inflammation, Hip Fracture
- Trial name
- ADhipfract (NCT02409082)
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Sahlgrenska University Hospital
Osteoarthritis, Rheumatoid Arthritis
Clinical Study Evaluating an Acetabular Cup System After Total Hip Replacement
This study is a clinical evaluation of survivorship of an acetabular cup system after total hip replacement using patient examinations and questionnaires.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Arthritis, Avascular Necrosis
- Trial name
- NCT00306930
- Testing
- Acetabular cup
- Where
- United States
- Volunteers
- 1,593 people
- Sponsor
- DePuy Orthopaedics
Hip Fractures, Acute Post Operative Pain
PENG vs SIFI Block for Positioning Pain During Spinal Anesthesia
This study aims to compare the effectiveness of preoperative ultrasound-guided suprainguinal fascia iliaca compartment block (SFICB) and pericapsular nerve group block (PENG) in preventing positioning pain during spinal…
- Conditions
- Hip Fractures, Acute Post Operative Pain, Nerve Block, Spinal Anesthesia
- Trial name
- NCT05549011
- Testing
- PENG Block, SIFI compartment block, Numeric Rating Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Hip Fractures
Patients With Acute Hip Fractures Will Receive Either the PENG Block or no Block Respectively.
Hip fracture pain is often severe and traditionally managed by systemic opioids which have increased risk of side effects in frail elderly patients.
- Trial name
- PENGBlock (NCT04996979)
- Testing
- Ropivacaine 0.5% Injectable Solution
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- Singapore General Hospital
Hip Fracture
Fascia Iliaca Compartment Blockade as Analgesia for Hip Fractures in the Acute Phase
To evaluate the analgesic potential of an neural blockade (Fascia iliaca compartment) with local anaesthetics in patients with hip fracture immediately after arrival in the emergency department.
- Trial name
- NCT00162630
- Testing
- Fascia Iliaca Compartment Blockade
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Hvidovre University Hospital
Hip Fracture
Back to the Future: Bridging the Hospital to Home Continuum After Hip Fracture
The purpose of this study is to determine whether is is feasible and acceptable to deliver a telephone based coaching intervention compared with education alone in community dwelling older adults (age 60 and older) after a fall…
- Trial name
- B2F (NCT01930409)
- Testing
- Telephone Support and Coaching, Education Only
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Pain, Acute, Postoperative Pain
Use of Dexamethasone Via Two Different Methods in PENG Block
Hip fractures are morbid conditions, especially in elderly patients, and their treatment is usually surgical. Pericapsular nerve group block targets the hip capsule.
- Conditions
- Pain, Acute, Postoperative Pain, Hip Fractures
- Trial name
- NCT06242028
- Testing
- Group P, Group S
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ondokuz Mayıs University
Fracture of Hip, Ileus
Peripheral Perfusion Index, Haemoglobin and Blood Transfusion in Acute Surgical Patients
The peripheral perfusion index (PPI) is a non-invasive, feasible measure of peripheral perfusion and, assumed, the overall circulation, which all patients are monitored by.
- Conditions
- Fracture of Hip, Ileus, Perforated Viscus, Anastomotic Leak
- Trial name
- NCT03795467
- Where
- Denmark
- Volunteers
- 1,500 people
- Sponsor
- Hvidovre University Hospital
Hip Fractures, Intraoperative Hypotension
Peri-operative Vasopressor Support in Patients Operated for an Acute Hip Fracture (AHF)
The incidence of hypotension perioperatively during operation of an acute hip fracture is unknown. As a surrogate factor the usage of vasopressor support is more adequate as the registration of vasopressor drugs are many times…
- Trial name
- NCT03497949
- Where
- Sweden
- Volunteers
- 997 people
- Sponsor
- Sahlgrenska University Hospital
Hip Fractures, Acute Pain
PENG Block for Traumatic Hip Fracture in the Emergency Department
The study is a multicenter single-blinded randomized comparative trial. Adult patients older than 20 years of age presenting with acute hip fracture in emergency department between January 1st, 2021 and December 31st, 2021 will…
- Conditions
- Hip Fractures, Acute Pain, Emergency Department
- Trial name
- NCT04997785
- Testing
- Ultrasound-guided Pericapsular Nerve Group (PENG) Block
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Dalin Tzu Chi General Hospital
Hip Fracture
Strength Training After Hip Fracture Surgery
The purpose of this study is to examine the effect of progressive strength training of the fractured limb in patients with hip fracture, during admittance in an acute orthopedic ward.
- Trial name
- NCT00848913
- Testing
- Rehabilitation with strength training, Rehabilitation without strength training
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Hvidovre University Hospital
Hip Fractures
Care Pathway for Sub-acute Hip Rehabilitation
The effectiveness of integrated care pathways for hip fractures in sub-acute rehabilitation settings is not known. The study objective was to assess if a hip fracture integrated care pathway at a sub-acute rehabilitation facility…
- Trial name
- NCT03906864
- Testing
- Care Pathway
- Where
- Singapore
- Volunteers
- 162 people
- Sponsor
- St Luke's Hospital, Singapore
Hypoalbuminemia, Acute Kidney Failure
The Relationship Between Hypoalbuminemia and Development of Acute Kidney Failure (AKI) According to KDIGO Criteria
This study was designed to determine the association between preoperative and postoperative hypoalbuminemia and AKI in older age hip fracture surgeons, to determine which period of hypoalbuminemia contributes more to AKI…
- Trial name
- NCT03675906
- Testing
- hypoalbuminemia
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Erzincan University