Clinical trials: Acute Hydrocephaly
Probable Alzheimer Disease, Parkinson Disease
In Vivo Alzheimer Proteomics
In France, an estimated 860 000 patients are affected by Alzheimer Disease (AD) which represents, as in other developed countries, a major public health issue.
- Conditions
- Probable Alzheimer Disease, Parkinson Disease, Neurological Disease Without Cognitive Degradation, Brain Trauma
- Trial name
- PROMARA (NCT02263235)
- Testing
- administration of stable isotope-labelled leucine-, collection of CSF, blood, urine, saliva
- Where
- France
- Volunteers
- 89 people
- Sponsor
- University Hospital, Montpellier
Acute Brain Injury, Traumatic Brain Injury
Bedside Cranial Ultrasound for Risk-Stratified Imaging in Pediatric Acute Brain Injury
Acute brain injury (ABI) is a leading cause of death and long-term disability in children. Diagnosis depends on fast neuroimaging, and head computed tomography (CT) is the bedside reference standard despite exposing the…
- Conditions
- Acute Brain Injury, Traumatic Brain Injury, Intracranial Hemorrhage, Hydrocephalus
- Trial name
- CUPID-Peds (NCT07772323)
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Virginia Commonwealth University
Cardiac Arrest, Stroke
Prevalence of Acute Critical Neurological Disease in Children: a Global Epidemiological Assessment
PANGEA is an international prospective point prevalence study to describe the epidemiology, interventions, and outcomes in children with acute critical brain disease.
- Conditions
- Cardiac Arrest, Stroke, Traumatic Brain Injury, Brain Mass
- Trial name
- PANGEA (NCT02381977)
- Testing
- No intervention
- Volunteers
- 922 people
- Sponsor
- University of Pittsburgh
Acute Brain Injury, Hydrocephalus
VentricuLostomy AssoCiaTed InfeCtions (LACTIC): Focus on CSF Lactate and Sampling Site
This observational study involving patients with acute brain injury undergoing treatment with an external ventricular drain consists of three subprojects, aiming to: 1.
- Conditions
- Acute Brain Injury, Hydrocephalus, External Ventricular Drain, External Ventricular Drainage Associated Infection
- Trial name
- LACTIC (NCT07380477)
- Testing
- Sampling of blood and cerebrospinal fluid
- Where
- Denmark
- Volunteers
- 148 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Disorder of Consciousness
Hydrocephalus Treatment on Persistent Disorder of Consciousness
After acute brain injury or haemorrhagic stroke, hydrocephalus might participate to consciousness disorder. We plan to explore whether ventriculoperitoneal shunt insertion improves consciousness in patients with vegetative or…
- Trial name
- HYCO (NCT05219331)
- Testing
- Ventriculoperitoneal shunt
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Toulouse
Intracranial Hemorrhages, Acute Ischemic Stroke
AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head Interpretation
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Intracranial Hemorrhages, Acute Ischemic Stroke, Hydrocephalus, Cerebral Infarction
- Trial name
- AI-REACT (NCT06018545)
- Testing
- Ground truthing, Reading
- Where
- 4 sites in United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust