Clinical trials: Acute Infectious Diseases
SARS-CoV 2, COVID-19
Assessment of the Psycho-social Impact of COVID-19 Outbreak
It has been shown in previous important outbreaks of infectious diseases that they have a huge impact on individuals and communities.
- Conditions
- SARS-CoV 2, COVID-19, Quality of Life, Mental Health Wellness 1
- Trial name
- COM-COVID (NCT04378452)
- Testing
- COM-COVID anonimous survey
- Where
- 4 sites in Spain
- Volunteers
- 56,656 people, healthy volunteers welcome
- Sponsor
- Fundació Institut Germans Trias i Pujol
Long COVID, Experience, Life
Living With Long COVID: LONGCOVID-EXPERIENCE
Background: One in ten people infected with COVID-19 presents persistent COVID, which consists of the presence of symptoms three months after the acute manifestations of COVID-19 and their persistence for at least two months…
- Trial name
- NCT06118112
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Corporacion Parc Tauli
Prone Positioning, High Flow Nasal Cannula
Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS
Coronavirus disease 2019 (COVID-19) is an emerging infectious disease that was first reported in Wuhan, China, and had subsequently spread worldwide. Twenty-nine percent of COVID-19 patients may develop ARDS.
- Conditions
- Prone Positioning, High Flow Nasal Cannula, Acute Respiratory Distress Syndrome, Corona Virus Infection
- Trial name
- NCT04325906
- Testing
- high flow nasal cannula (HFNC), Prone positioning (PP)
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Rush University Medical Center
SARS-CoV2 Infection, SARS-CoV-2 Acute Respiratory Disease
SABRE: A Single-arm Prospective Study Measuring Safety and Tolerability of SARS-CoV-2 Neutralising Antibodies in High-risk Populations
The SABRE study is a single-arm prospective study measuring safety, tolerability and pharmacokinetics of two SARS-CoV-2 neutralising antibodies (BMS-986414 and BMS-986413) amongst high-risk special populations of vaccine…
- Conditions
- SARS-CoV2 Infection, SARS-CoV-2 Acute Respiratory Disease, Myeloma, Leukemia
- Trial name
- SABRE (NCT05393999)
- Testing
- BMS-986414, BMS-986413
- Where
- United Kingdom
- Sponsor
- Imperial College Healthcare NHS Trust
Long Covid-19, PASC Post Acute Sequelae of COVID 19
A Pilot rTMS Trial for Neuropsychiatric Symptoms of Long-COVID
This is a pilot randomized trial of rTMS for symptoms of fatigue and brain fog, and other neuropsychiatric symptoms of Long-COVID (Post-COVID, post-acute sequelae of COVID-19 infection, PASC).
- Conditions
- Long Covid-19, PASC Post Acute Sequelae of COVID 19, Brain Fog, Fatigue
- Trial name
- NCT06586398
- Testing
- rTMS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, Los Angeles
Long COVID, Post-COVID Conditions
Transcranial Direct Current Stimulation for Long COVID Brain Fog and Fatigue
Long COVID can cause persistent symptoms such as fatigue, cognitive difficulties commonly described as brain fog, reduced exercise tolerance, and impaired quality of life.
- Conditions
- Long COVID, Post-COVID Conditions, Fatigue, Cognitive Dysfunction
- Trial name
- NEUROSTIM-LC (NCT07709234)
- Testing
- Transcranial Direct Current Stimulation
- Volunteers
- 20 people
- Sponsor
- University of Las Palmas de Gran Canaria
Respiratory Syncytial Virus Infections
Identification and Clinical Validation of Biomarkers Associated With Clinical Severity in Adults Infected With RSV
A short description, 5000 characters Intro: Respiratory Syncytial Virus (RSV) is a frequent, ubiquitous agent of respiratory viral infections.
- Trial name
- ARF-RSV (NCT06197152)
- Testing
- Nasopharyngeal swabs and biological collection
- Where
- France
- Volunteers
- 133 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19, Long Haul
Covid-19 Long Haul Preventative and Health Promotion Care Clinical Trial Acceleration Program.
Investigators are conducting a study on alternative treatments for patients who have received an current or previous positive COVID-19 diagnosis with mild-serve symptoms or undiagnosable condition after testing positive for…
- Trial name
- NCT06441955
- Testing
- Ritonavir-Boosted Nirmatrelvir (Paxlovid), Physiological Evaluation, Moderna COVID-19 Vaccine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Well- Konnect Healthcare Services and Research Firm
Acute Respiratory Distress Syndrome, Ventilator Associated Pneumonia
Macrophage Programing in Acute Lung Injury: MiniBAL
The goal of this observational clinical trial is to learn about the role white blood cells (macrophages) play in lung inflammation in people with Acute Respiratory Distress Syndrome (ARDS).
- Trial name
- NCT05767671
- Testing
- Non-Bronchoscopic Mini Bronchoalveolar Lavage
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- William Janssen, MD
Acute Disease, Sepsis
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Research in acute care faces many challenges, including enrollment challenges, legal limitations in data sharing, limited funding, and lack of singular ownership of the domain of acute care.
- Conditions
- Acute Disease, Sepsis, Pneumonia, Frailty
- Trial name
- Acutelines (NCT04615065)
- Where
- Netherlands
- Volunteers
- 35,000 people
- Sponsor
- University Medical Center Groningen
Infection Viral, Exercise
Exercise Influence on COVID-19
An observational study is carried out in the university population of the University of Salamanca to know the impact of the COVID-19 pandemic and the influence of physical exercise on the severity of symptoms.
- Conditions
- Infection Viral, Exercise, Coronavirus, Habits
- Trial name
- NCT04624048
- Testing
- COVID-19 survey
- Volunteers
- 30,000 people
- Sponsor
- University of Salamanca
Post Acute COVID-19 Syndrome
Effects of Immulina TM Supplements With PASC Patients
This is a multi-site study that will try to determine the effects of Immulina ™, a natural dietary supplement, on blood chemicals associated with inflammation that are often increased in patients with long COVID (also called…
- Trial name
- NCT05524532
- Testing
- Immulina TM
- Where
- 9 sites in United States, Puerto Rico
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Pain
Study of Non Inferiority Bi-Profenid® 200mg Versus Bi-Profenid® 300mg Among Patients Presenting of the Post-traumatic or Rheumatologic Acute Affections of the Locomotor Apparatus (BIPROPAIN)
Primary objective: To demonstrate the non-inferiority of Bi-Profenid 100 mg x 2 day versus Bi-Profenid 150 mg x 2 day in patients presenting with pain related to closed, benign, acute post-traumatic conditions of the motor system…
- Trial name
- NCT00810121
- Testing
- ketoprofen 100 mg, ketoprofen
- Where
- France
- Volunteers
- 409 people
- Sponsor
- Sanofi
Post-Acute COVID19 Syndrome, Long COVID
Exercise Intervention Using mHealth in Patients With Post-Acute COVID-19 Syndrome: a Randomized Clinical Trial
Post-Acute Syndrome COVID-19 is a disease resulting from infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Conditions
- Post-Acute COVID19 Syndrome, Long COVID, Post COVID-19 Condition
- Trial name
- COVIDReApp (NCT05725538)
- Testing
- COVIDReApp Group, Control Group
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Cadiz
Post COVID-19 Condition
Prospective Multidisciplinary Post-COVID-19 Registry Tyrol
Longitudinal, prospective observational cohort study enrolling patients with persisting symptoms (> 12 weeks) after COVID-19 in a multidisciplinary care model.
- Trial name
- PRECISE (NCT05545332)
- Where
- Austria
- Volunteers
- 600 people
- Sponsor
- Medical University Innsbruck
Coronavirus Infection, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Safety, Immunogenicity, and Efficacy of INO-4800 for COVID-19 in Adults at High Risk of SARS-CoV-2 Exposure
This is a Phase 2/3, randomized, placebo-controlled, multi-center trial to evaluate the safety, immunogenicity and efficacy of INO-4800 administered by intradermal (ID) injection followed by electroporation (EP) using CELLECTRA®…
- Conditions
- Coronavirus Infection, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), COVID-19 Disease
- Trial name
- NCT04642638
- Testing
- INO-4800, CELLECTRA® 2000
- Where
- 27 sites in United States, Colombia and 1 more
- Volunteers
- 1,307 people, healthy volunteers welcome
- Sponsor
- Inovio Pharmaceuticals
Robotic Exoskeleton, Post-acute Covid-19 Syndrome
Robotic Assisted Hand Rehabilitation Outcomes in Adults After COVID-19
Prolonged hospitalization in severe COVID-19 cases can lead to substantial muscle loss and functional deterioration. While rehabilitation is vital, conventional approaches encounter capacity constraints.
- Conditions
- Robotic Exoskeleton, Post-acute Covid-19 Syndrome, Rehabilitation Outcome, Physical And Rehabilitation Medicine
- Trial name
- NCT06137716
- Testing
- Training with a Robotic Hand Exoskeleton
- Where
- Spain
- Volunteers
- 13 people
- Sponsor
- University of Valladolid
Fatigue, Post-Acute COVID-19 Syndrome
Immunoadsorption vs. Sham Treatment in Post COVID-19 Patients With Chronic Fatigue Syndrome
The complex clinical symptoms of post COVID syndrome, especially chronic fatigue, pose a major challenge to patients and to the health care system and are frequently refractory to therapeutic intervention.
- Trial name
- NCT05954325
- Where
- Germany
- Volunteers
- 63 people
- Sponsor
- Hannover Medical School
Acute Respiratory Distress Syndrome, Corona Virus Infection
Knowledge, Attitude and Practice of Dental Students About COVID-19
Coronavirus disease 2019 (abbreviated "COVID- 19") is a pandemic respiratory disease that is caused by a novel coronavirus and was first detected in December 2019 in Wuhan, China.
- Conditions
- Acute Respiratory Distress Syndrome, Corona Virus Infection, Acute Lung Injury, Fever
- Trial name
- NCT04449081
- Testing
- Knowledge, Attitude, Practice, Awareness, Preference
- Where
- Malaysia
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Post COVID Condition
SuperCAP Program to Improve Cognition and Daily Functioning in Post-COVID-19 Condition
The goal of this study is to determine whether the SuperCAP intervention program is superior to control in reducing disability from baseline to the post-intervention assessment in people with Post-COVID-19 Condition.
- Trial name
- NCT07530757
- Testing
- SuperCAP intervention program, Psychoeducational intervention
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
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