Clinical trials: Acute Intradialytic Hypotension
Acute Kidney Injury, Fluid Overload
Restrictive Versus Liberal Rate of Extracorporeal Volume Removal Evaluation in Acute Kidney Injury
Critically ill patients with acute kidney injury and fluid overload who are frequently treated by fluid removal during dialysis are at an increased risk of complications and death.
- Conditions
- Acute Kidney Injury, Fluid Overload, Hypotension, Dialysis; Complications
- Trial name
- RELIEVE-AKI (NCT05306964)
- Testing
- Restrictive UFnet Rate Strategy, Liberal UFnet Rate Strategy
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- University of Pittsburgh
Acute Kidney Injury
Continuous Central Venous Oxygen Saturation Measurement as a Tool to Predict Hemodynamic Instability Related to Renal Replacement Therapy in Critically Ill Patients
Acute kidney injury (AKI) is common in intensive care unit (ICU) and inducing a high morbidity and mortality. In severe forms of AKI (more than 25% of AKI patients admitted to the ICU), renal replacement therapy (RRT) is often…
- Trial name
- SoVHIRR (NCT05897840)
- Testing
- Fiber-optic probe CeVOX
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Acute Kidney Injury, Shock
Methylene Blue for the Prevention of Hypotension During Hemodialysis
Hypotension is a common complication of intermittent renal replacement therapy. Methylene blue, an inhibitor of nitric oxide synthesis, has been suggested to improve hemodynamics during renal replacement therapy in ambulatory…
- Conditions
- Acute Kidney Injury, Shock, Intradialytic Hypotension, Intradialytic Hypertension in Hemodialysis Patients
- Trial name
- BLUE (NCT05092165)
- Testing
- Methylene Blue, Control
- Where
- Brazil
- Volunteers
- 261 people
- Sponsor
- Federal University of São Paulo
Acute Kidney Injury, Acute Renal Failure
Prevention of Intradialytic Hypotension in Acute Kidney Injury Patients
Intradialytic hypotension (IH) is a major complication during acute hemodialysis. The aim of this study was to evaluate the effects of dialysate temperature (DT) reduction with Na and ultrafiltration (UF) profiling on…
- Trial name
- NCT00971971
- Testing
- Dialysis, Standard SLED
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Sao Jose do Rio Preto Medical School
Hypotension During Dialysis, Fluid Overload
Fluid Mobilization in Hospitalized Patients With Acute Kidney Injury
Hospitalized patients often suffer from an acute shutdown of kidney function secondary to infections, use of antibiotics, or use of intravenous contrast agents.
- Trial name
- NCT04522635
- Testing
- (100 ml of Albumin 25%)
- Volunteers
- 65 people
- Sponsor
- University of California, San Diego
Acute Kidney Injury, Intra-dialytic Hypotension
Low Dialysate Temperature During SLED
Objectives: This study is evaluating the hemodynamic effects of lowering the dialysate temperature in acute kidney injury (AKI) patients submitted to sustained low efficiency dialysis (SLED) in a single large center.
- Trial name
- NCT03397992
- Testing
- Changing dialysate temperature
- Volunteers
- 38 people
- Sponsor
- Washington University School of Medicine
Intradialytic Hypotension, Cardiac Event
BIA Versus Physician Adjustment in Acute Kidney Injury Patients Requiring Renal Replacement Therapy
This study was designed to compare the efficacy of BIA and physician adjustment to prevent intradialytic hypotension in patients with acute kidney injury who received renal replacement therapy.
- Conditions
- Intradialytic Hypotension, Cardiac Event, Renal Insufficiency, Hospital Length of Stay
- Trial name
- NCT03916861
- Testing
- Bioelectrical Impedance Analysis, Physician-guided
- Where
- Thailand
- Volunteers
- 9 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Acute Intradialytic Hypotension
Observational Study to Assess Oxygen Saturation Predictive Power Related to Intradialytic Acute Hypotension
The aim of the present work was to analyze the short-term variability of SO2 during hemodialysis in sessions with and without hypotension to correlate the SO2 variability to hemodynamic instability.
- Trial name
- SOGLIA (NCT01759641)
- Testing
- Hypotension-prone patients
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
End Stage Renal Disease, Hypotension During Dialysis
Effect of Protein Intake During Hemodialysis on Blood Pressure and Arterial Stiffness Indices
Open label, randomized, cross-over clinical study comparing the acute effect of high versus low protein meals during dialysis on intradialytic blood pressure, 24-hour ambulatory blood pressure and arterial stiffness indices on…
- Conditions
- End Stage Renal Disease, Hypotension During Dialysis, Protein Malnutrition, Arterial Sclerosis
- Trial name
- NCT03947710
- Testing
- High-protein meals, Low- protein meals, No meals
- Where
- Greece
- Volunteers
- 45 people
- Sponsor
- Aristotle University Of Thessaloniki
Acute Kidney Injury, Dialysis Hypotension
Outpatient Recovery From Acute Kidney Injury Requiring Dialysis
There are currently no therapies to improve the chances of recovering enough kidney function to come off of dialysis after severe acute kidney injury.
- Trial name
- ORKID (NCT05158153)
- Testing
- ORKID Bundled Intervention, Furosemide
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of California, San Francisco
Acute Kidney Injury, Chronic Kidney Disease Stage 5 on Dialysis
Non-invasive Assessment to Predict Tolerance to Fluid Removal on Intermittent Kidney Replacement Therapy
This prospective cohort study aim to investigate the ability of multiple types of assessments including 1) the modified Venous Excess Ultrasound (VExUS) assessment, 2) non-invasive estimation of absolute blood volume (ABV), and…
- Conditions
- Acute Kidney Injury, Chronic Kidney Disease Stage 5 on Dialysis, Chronic Kidney Failure, Intradialytic Hypotension
- Trial name
- TECHNO-HDF (NCT05270759)
- Testing
- Estimated absolute blood volume, Modified VExUS evaluation
- Where
- Canada
- Volunteers
- 93 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Acute Kidney Injury
Midodrine is Effective in Management of Intradialytic Hypotension Among Critically-ill Patients With Acute Kidney Injury
The aim of this randomized trial was to assess the efficacy of oral midodrine tablets for the management of intradialytic hypotension among critically ill patients with acute kidney injury.
- Trial name
- NCT03431194
- Testing
- midodrine
- Volunteers
- 80 people
- Sponsor
- Benha University