Clinical trials: Acute Ischemic Stroke Patients
Ischemic
Exploratory Study on the Effects of Early Rosuvastatin Treatment in Patients With Acute Ischemic Stroke
This is an exploratory, randomized, open-label, 2-arm, parallel-group study exploring the efficacy of rosuvastatin (20mg/day) in patients with acute ischemic stroke.
- Trial name
- AIS (NCT02643784)
- Testing
- Rosuvastatin, Control
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Acute Stroke
Efficacy of Whole Extract of Licorice in Neurological Improvement of Patients After Acute Ischemic Stroke
Stroke is one of the most important causes of mortality and disability both in developed and developing countries. The only food and drug administration (FDA) approved therapy for acute stroke is recombinant tissue plasminogen…
- Trial name
- NCT02473458
- Testing
- Licorice whole extract
- Where
- Iran
- Volunteers
- 75 people
- Sponsor
- Shiraz University of Medical Sciences
Acute Ischemic Stroke
Sodium Valproate in Patients With Acute Ischemic Stroke
The purpose of this pilot trial is to investigate the feasibility, safety, and efficacy of sodium valproate in patients with acute ischemic stroke, and also explore the mechanism: whether valproate increases peripheral…
- Trial name
- NCT06020898
- Testing
- Sodium valproate, Normal saline
- Where
- China
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital
Cardiovascular Diseases, Acute Coronary Syndrome
The IndONEsia ICCU Registry: a Multicenter Cohort of Intensive Cardiovascular Care Units Patients in Indonesia
Patients in the Intensive Cardiovascular Care Unit (ICCU) often present with cardiovascular disease (CVD) issues accompanied by various non-cardiovascular conditions.
- Conditions
- Cardiovascular Diseases, Acute Coronary Syndrome, Heart Failure, Heart Disease, Coronary
- Trial name
- NCT06265714
- Where
- 9 sites in Indonesia
- Volunteers
- 12,950 people
- Sponsor
- Universitas Indonesia
Acute Ischemic Stroke
Efficacy and Safety of AngongNiuhuang Pill in Patients With Acute Ischemic Stroke (ANGONG TRIAL)
AngongNiuhuang pill has obvious effects on the cardiovascular and cerebrovascular diseases. Pharmacological experiments confirmed that AngongNiuhuang pill can protect blood-brain barrier, inhibit capillary permeability, improve…
- Trial name
- NCT04475328
- Testing
- AngongNiuhuang pill, Standard treatment
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking Union Medical College Hospital
Acute Ischemic Stroke, Tenecteplase
Intravenous Tenecteplase in Very Old Patients With Acute Ischemic Stroke
The benefit of intravenous tenecteplase in very old patients with acute ischemic stroke (AIS) remain uncertain. This real-world study aims to evaluate the effectiveness and safety of intravenous tenecteplase in AIS patients aged…
- Trial name
- NCT07475936
- Testing
- Tenecteplase (TNK) (0.25 mg/kg, to maximum of 25mg), Standard medical care
- Where
- China
- Volunteers
- 392 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
Acute Stroke, Transient Ischemic Attack
The Recurrence Study
The primarily goal of the research is to better understand progression of disease in patients who present with an acute stroke to the Hamad General Hospital (HGH) stroke and Transient Ischemic Attack (TIA) clinic.
- Trial name
- NCT03244215
- Testing
- Corneal Confocal Imaging, Magnetic resonance Imaging, Blood sample
- Where
- Qatar
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Acute Ischemic Stroke
Anesthesia Technique and Outcomes in Mechanical Thrombectomy for Acute Ischemic Stroke
This retrospective cohort study examined clinical outcomes in patients who underwent mechanical thrombectomy for acute ischemic stroke under general anesthesia or sedoanalgesia.
- Trial name
- NCT07422649
- Testing
- General Anesthesia, Sedoanalgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 481 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Stroke, Transient Ischemic Attack
Copeptin for Risk Stratification in Acute Stroke Patients: the CoRisk Study
Prospective observational multicenter study to evaluate copeptin as a prognostic marker in patients with an acute cerebrovascular event.
- Trial name
- CoRisk (NCT00878813)
- Testing
- Sampling of 15ml blood, Blood-Sampling
- Where
- 4 sites in Germany, Switzerland
- Volunteers
- 1,102 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ischemic Stroke
ReStore Thrombectomy Trial for Flow Restoration in Acute Ischemic Stroke Patients
The ReStore™ Thrombectomy device restores blood flow in the neurovascular by removing thrombus in patients experiencing ischemic stroke.
- Trial name
- NCT01437774
- Testing
- thrombectomy (ReStore or Merci)
- Where
- 4 sites in United States
- Volunteers
- 210 people
- Sponsor
- Reverse Medical Corporation
Acute Ischemic Stroke
Study of the KPCXM18 Injection for Treatment of Acute Ischemic Stroke
This study is a multicenter, randomized, double-blind, parallel, placebo-controlled trial design to evaluate the efficacy and safety of the KPCXM18 injection at different doses for the treatment of acute ischemic stroke and its…
- Trial name
- NCT05745311
- Testing
- The KPCXM18 injection
- Volunteers
- 240 people
- Sponsor
- Kunming Pharmaceuticals, Inc.
Ischemic Stroke
Administration of CBG000592 (Riboflavin/Vitamin B2) in Patients With Acute Ischemic Stroke
Administration of CBG000592 (riboflavin/vitamin B2) in patients with acute ischemic stroke to know if it causes a reduction of glutamate-mediated excitotoxicity.
- Trial name
- NCT02446977
- Testing
- Vitamin B2 Streuli®, Solution for injection
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Castillo, José, M.D.
Stroke
Efficacy and Safety Study of GM602 in Patients With Acute Middle Cerebral Artery Ischemic Stroke Within 18 Hours
The purpose of this research study is to determine whether the investigational drug GM602, is effective and safe in the treatment of ischemic stroke (strokes caused by a blood clot blocking the flow of blood through one, or more…
- Trial name
- GMAIS (NCT01221246)
- Testing
- GM602
- Where
- 8 sites in United States
- Volunteers
- 34 people
- Sponsor
- Genervon Biopharmaceuticals, LLC
Ischemic Stroke, Paroxysmal Atrial Fibrillation
Paroxysmal Atrial Fibrillation in Patients With Acute Ischemic Stroke
The purpose of this study is to estimate the clinical relevance of monitoring patients with acute ischemic stroke with 48 hours' inpatient cardiac telemetry in relation to evaluate the presence of brief runs of premature atrial…
- Conditions
- Ischemic Stroke, Paroxysmal Atrial Fibrillation, Premature Atrial Complexes
- Trial name
- NCT02610803
- Where
- Denmark
- Volunteers
- 863 people
- Sponsor
- Odense University Hospital
Ischemic Stroke, Neurological Injury
Omega 3 and Ischemic Stroke; Fish Oil as an Option
In this trial, The investigators are going to investigate the improvement of neurological functions and infarced area of the brain in ischemic stroke patients after ingestion of omega 3 products that have high concentrations of…
- Conditions
- Ischemic Stroke, Neurological Injury, Stroke, Acute, Inflammatory Response
- Trial name
- OmegaStroke (NCT04386525)
- Testing
- Omega-3 fish oil
- Volunteers
- 60 people
- Sponsor
- King Fahad Medical City
Diabetes Mellitus, Type 2, Acute Coronary Syndrome
Cardiovascular Outcomes Study of Alogliptin in Patients With Type 2 Diabetes and Acute Coronary Syndrome
The purpose of this study is to evaluate the cardiovascular outcomes of alogliptin, once daily (QD), compared with placebo, in addition to standard of care, in patients with type 2 diabetes mellitus and acute coronary syndrome.
- Trial name
- EXAMINE (NCT00968708)
- Testing
- Alogliptin
- Where
- 908 sites in United States, Argentina and 48 more
- Volunteers
- 5,380 people
- Sponsor
- Takeda
Stroke
Study on the Efficacy of Alprostadil Injection in Patients With Acute Ischemic Stroke
Ischemic stroke has a variety of treatments and currently drug therapy is one of the main treatments.A number of clinical studies have proved that alprostadil (PGE1) has pharmacological effects of significant dilation of blood…
- Trial name
- NCT03252626
- Testing
- Alprostadil, Normal saline
- Volunteers
- 950 people
- Sponsor
- The First Hospital of Jilin University
Stroke, Stroke, Acute
Data Collection of Patients Admitted to the Stroke Unit
The purpose of this prospective observational study is to create a database in which data will be collected from every patient admitted to the Stroke unit and who has explicitly given his or her informed consent for this data…
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic, Stroke Hemorrhagic
- Trial name
- PRODA-STROKE (NCT04956185)
- Where
- Belgium
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Ghent
Stroke, Acute Ischemic Stroke
Repinotan in Patients With Acute Ischemic Stroke
The purpose of this trial is to evaluate Repinotan HCl in patients with acute ischemic stroke. At study entry patients will be randomized to Repinotan HCl or placebo in a 1:1 ratio. The total treatment period wil be 72 hours.
- Trial name
- NCT00044915
- Testing
- Repinotan HCl (BAYX3702)
- Where
- 119 sites in United States, Australia and 13 more
- Volunteers
- 782 people
- Sponsor
- Bayer
Stroke, Ischemic
A Study of the Use of the Q Aspiration Catheter to Remove Clot in Stroke Patients
The purpose of this study is to collect real-world safety and performance data on the MIVI Neuroscience, Inc. Q Aspiration Catheter for use in the removal of fresh, soft emboli and thrombi in the neurovascular system during acute…
- Trial name
- TAPAS (NCT04089917)
- Testing
- Q Aspiration Catheter
- Where
- 4 sites in Spain
- Volunteers
- 45 people
- Sponsor
- MIVI Neuroscience, Inc.