Clinical trials: Acute Ischemic Stroke Patients
Acute Ischemic Stroke AIS
Palmitoylethanolamide and Luteolin in Patients with Acute Ischemic Stroke
Acute ischemic stroke is caused by reduced blood supply to the brain associated with neuroinflammation. This mechanism contributes to acute neuronal death and persists even after reopening of the closed vessel, with consequent…
- Trial name
- NCT06777680
- Testing
- co-ultramicronized Palmitoylethanolamide + Luteolin (770 mg), Thrombectomy
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Ospedali Riuniti Trieste
Brain Ischemia With Non-valvular Atrial Fibrillation, Transient Ischemic Attack With Non-valvular Atrial Fibrillation
Prospective Record Of the Use of Dabigatran in Patients With Acute Stroke or TIA
The multi-center, prospective PRODAST study is investigating patients with non-valvular atrial fibrillation (AF) who experienced an ischemic stroke or a transient ischemic attack (TIA) recently (≤ 1 week) both with and without…
- Trial name
- PRODAST (NCT02507856)
- Where
- 90 sites in Germany
- Volunteers
- 10,044 people
- Sponsor
- University Hospital, Essen
Acute Stroke
tDCS in Acute Stroke Patients
Very early after the onset of the focal perfusion deficit, excitotoxic mechanisms can lethally damage neurons and glia. Excitotoxicity triggers a number of events that can further contribute to tissue death.
- Trial name
- tDCS (NCT02806856)
- Testing
- tDCS neuroConn
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier St Anne
Stroke, Acute, Ischemic Stroke
Remote Ischemic Conditioning in Patients With Acute Stroke (RESIST)
Our primary aim is to investigate whether remote ischemic conditioning (RIC) as an adjunctive treatment can improve long-term recovery in acute stroke patients as an adjunct to standard treatment.
- Conditions
- Stroke, Acute, Ischemic Stroke, Hemorrhagic Stroke, Intracerebral Hemorrhage
- Trial name
- RESIST (NCT03481777)
- Testing
- Remote Ischemic Conditioning
- Where
- 4 sites in Denmark
- Volunteers
- 1,500 people
- Sponsor
- Grethe Andersen
Ischemic Stroke, Acute
Predictors of Post-Thrombectomy Cognitive Impairment in Acute Ischemic Stroke Patients
This prospective cohort study investigates predictors of post-stroke cognitive impairment (PSCI) in patients undergoing endovascular thrombectomy (EVT) for acute ischemic stroke due to large vessel occlusion.
- Trial name
- NCT07235423
- Volunteers
- 120 people
- Sponsor
- Assiut University
Acute Ischemic Stroke, Atrial Fibrillation
Multimodal Prognostic Assessment of Acute Ischemic Stroke Patients With Atrial Fibrillation: a Prospective, Multicenter, Observational Study (IAT-CLOSURE)
The main purpose of this study is to investigate the safety and outcomes of different treatment strategies, including best medical therapy (OAC [oral anticoagulation], antiplatelet [APT]) and left atrial appendage closure [LAAC]…
- Trial name
- NCT06548269
- Testing
- Cardiologic work-up
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Jinan Central Hospital
Ischemic Stroke, Sleep Apnea Syndrome
Screening and Treatment of SAHS in Patients With Acute Ischemic Stroke
Ischemic stroke is a kind of common disease with great harm. In acute stage of stroke there is sharply increasing morbidity of sleep apnea hypopnea syndrome.
- Trial name
- SAHS (NCT02029183)
- Testing
- Bi level positive pressure ventilation, bi-level positive airway pressure
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University
Acute Stroke Intervention, Acute Stroke
Using AI Systems to Optimize the Clinical Outcome of Stroke Patients
This project addresses the imminent challenge of providing adequate motor rehabilitation to a growing number of stroke survivors amidst the ageing population, decreasing age of stroke, and shortage of physical/occupational…
- Conditions
- Acute Stroke Intervention, Acute Stroke, Acute Ischemic Stroke
- Trial name
- NCT06828679
- Testing
- Acupuncture, control group, Robotic Training
- Where
- Hong Kong
- Volunteers
- 400 people
- Sponsor
- Chinese University of Hong Kong
Acute Ischemic Stroke
Radial Versus Femoral Access For Thrombectomy in Patients With Acute Basilar Artery Occlusion
Stroke is one of the most important diseases endangering the health and quality of life of Chinese people. Acute ischemic stroke (AIS) is commonly caused by cerebrovascular stenosis or occlusion.
- Trial name
- NCT05903560
- Testing
- endovascular recanalization via radial approach, endovascular recanalization via femoral approach
- Where
- China
- Volunteers
- 386 people
- Sponsor
- Jinling Hospital, China
Acute Ischemic Stroke, Stroke
Early Feasibility Study of RapidPulseTM Aspiration System for Patients With Acute Ischemic Stroke
The goal of this clinical trial is to assess the initial safety and performance of the RapidPulseTM Aspiration System in patients experiencing acute ischemic stroke within 24 hours since the onset of stroke symptoms, or last…
- Conditions
- Acute Ischemic Stroke, Stroke, Large Vessel Occlusion, Mechanical Thrombectomy
- Trial name
- PULSE-C (NCT05899036)
- Testing
- RapidPulseTM Aspiration System
- Where
- 2 sites in Paraguay, Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- RapidPulse, Inc
Ischemic Stroke, Consciousness Disorder
Transcranial Magnetic Stimulation in Disorder of Consciousness in Acute Severe Cerebrovascular Disease Patients
This study is aimed at evaluating the potential of transcranial magnetic stimulation in patients with acute severe ischemic stroke with DoC while assessing patients with a hybrid neural network evaluation model.
- Conditions
- Ischemic Stroke, Consciousness Disorder, Transcranial Magnetic Stimulation
- Trial name
- I-HELP (NCT05670873)
- Testing
- Transcranial magnetic stimulation
- Volunteers
- 50 people
- Sponsor
- Liping Liu
Stroke, Ischemic, Tomography, X-Ray Computed
DECT for Differentiating Intracerebral Hemorrhage From Contrast Extravasation
The goal of this clinical trial is to investigate the use of DECT (Dual-Energy Computed Tomography) in patients with acute ischemic stroke who receive an intervention (thrombolysis or thrombectomy).
- Trial name
- DECT-ICH (NCT05675774)
- Testing
- Dual Energy CT
- Where
- Canada
- Volunteers
- 189 people
- Sponsor
- University of Manitoba
Ischemic Stroke
Thrombectomy in Patients Ineligible for iv tPA
the purpose of this study is to to compare the safety and effectiveness of stent-retrievers as a device class group with best medical care alone in the treatment of acute ischemic stroke (AIS) in patients who are not eligible for…
- Trial name
- THRILL (NCT02135926)
- Testing
- Thrombectomy, Best medical care
- Where
- 19 sites in Austria, Germany
- Volunteers
- 4 people
- Sponsor
- University Hospital Heidelberg
Acute Ischemic Stroke
Head Down Tilt 15° to Increase Collateral Flow in Acute Ischemic Stroke
The DOWN-SUITE study is multicenter, randomised, controlled, open-label clinical trial with blinded outcome assessment comparing collateral status in patients with acute ischemic stroke treated with an in-hospital application of…
- Trial name
- DOWN-SUITE (NCT06297863)
- Testing
- HEAD DOWN TILT -10° to -15°
- Where
- 6 sites in Italy
- Volunteers
- 118 people
- Sponsor
- University of Milano Bicocca
Acute Ischemic Stroke
Protective Effects of Edaravone Dexborneol
The patients of acute ischemic stroke were divided into two groups, edaravone dexborneol treatment group and edaravone treatment group.
- Trial name
- NCT05024526
- Testing
- edaravone dexborneol or edaravone
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Lili Cao
Acute Ischaemic Stroke
Efficacy and Security of an Endovascular Treatment as First Choice Procedure Compared With a Standard Intravenous Thrombolytic Therapy Treatment for Patients With Acute Ischemic Stroke Within 4.5 Hours After Onset
This study will compare two ways of treatment for acute ischemic stroke: an endovascular treatment (EVT), defined as intraarterial thrombolysis and/or mechanical thrombectomy as a first choice treatment versus intravenous…
- Trial name
- FUN-TPA (NCT02164357)
- Testing
- EVT (endovascular treatment ), IVT (intravenous thrombolytic therapy)
- Where
- 5 sites in Spain
- Volunteers
- 124 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Stress Hyperglycemia
Stress Hyperglycemia and Acute Ischemic Stroke
Whereas diabetes mellitus is clearly a risk factor for the occurrence of stroke and for its poor prognosis, hyperglycemia per se is also linked to increased morbidity and mortality in stroke patients.Therefore, the objective of…
- Trial name
- NCT04408768
- Testing
- standard protocol for stroke patients
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Stroke, Brain Ischemia
Early Administration of Aspirin in Patients With Acute Ischemic Stroke Treated With Systemic Thrombolysis
The aim of this study is to determine whether early administration of aspirin in acute ischemic stroke patients treated with systemic thrombolysis is safe and can improve outcomes due to decreasing the number of early…
- Trial name
- NCT02921360
- Testing
- acetylsalicylic acid
- Volunteers
- 120 people
- Sponsor
- City Clinical Hospital No. 67, Moscow, Russia
Myocardial Infarction
Studying the Effectiveness of Early Invasive Treatment in Elderly Patients With High-risk Non-ST-segment Elevation Acute Coronary Syndrome.
The goal of this is observational study is to compare about MACE events and predisposing factors related to MACE events in elderly patients with high-risk non-ST acute coronary syndromes receiving early versus late invasive…
- Trial name
- NCT06486233
- Where
- Vietnam
- Volunteers
- 385 people
- Sponsor
- Gia Dinh People Hospital
Ischemic Stroke, Ischemic Stroke, Acute
Tegoprazan for Prevention of Gastrointestinal Complication in Ischemic Stroke Patients on Antiplatelet Therapy (TegoStroke)
Patients with ischemic stroke commonly receive antiplatelet therapy, frequently starting as dual antiplatelet therapy, which is associated with an increased risk of gastrointestinal complications.
- Conditions
- Ischemic Stroke, Ischemic Stroke, Acute, Transient Ischemic Attack (TIA), Cerebrovascular Disease
- Trial name
- TegoStroke (NCT07687706)
- Testing
- Tegoprazan 50 mg
- Where
- 24 sites in South Korea
- Volunteers
- 1,524 people
- Sponsor
- Hanyang University Guri Hospital