Clinical trials: Acute Musculoskeletal Pain
Postoperative Pain, Acute, Shoulder Pain
Evaluating Intercostobrachial Nerve Block's Effect on Pain Control After Shoulder Replacement
Interscalene blocks are frequently performed to decrease postoperative pain after shoulder surgeries and are considered the gold standard for pain control after this type of surgery.
- Trial name
- NCT06042608
- Testing
- intercostobrachial nerve block
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Acute Pain, Surgery
Auriculotherapy for Surgical Pain
The current opioid epidemic has led to a renewed interest in exploring non-pharmacological techniques to treat post-operative pain.
- Conditions
- Acute Pain, Surgery, Shoulder Pain
- Trial name
- NCT03860259
- Testing
- Auriculotherapy cryopuncture device without nitrogen gas, Auriculotherapy cryopuncture device with nitrogen gas
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jacques E. Chelly
Physical Endurance, Muscle Fatigue
Assessment of the Acute Effect of Cycling Practice in Lumbar and Thigh Muscles
Introduction: Cycling represents a very important level of practice, being among the most practiced sports in Spain. As in any other sport discipline, its practice is associated with the appearance of overloads and sports…
- Conditions
- Physical Endurance, Muscle Fatigue, Musculoskeletal Pain, Muscle Tightness
- Trial name
- NCT03442933
- Testing
- 3 hours Road Cycling Time Trial, 3 hours Mountain Biking Time Trial
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Insomnia, Healthy Adult
The Impact of Acute Pain on Sleep Parameters in the Insomnia Population and Healthy Controls
This study investigates how acute exercise-induced muscular pain affects sleep quality and sleep architecture in people with insomnia compared to healthy sleepers.
- Conditions
- Insomnia, Healthy Adult, Sleep, Musculoskeletal Pain
- Trial name
- NCT07826650
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Temporomandibular Joint and Muscle Disorder
An Implementation and Biobehavioral Study of Temporomandibular Joint and Muscle Disorder (TMJMD)
With the great economic costs and traditionally poor outcomes among chronic temporomandibular joint and muscle disorder (TMJMD) patients, it has become important to treat patients in the acute state, in order to prevent these…
- Trial name
- NCT00952900
- Testing
- Biobehavioral, Active Coping/Attention Intervention
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Pain, Opiate
Intensive Cryotherapy in the Emergency Department for Acute Musculoskeletal Injuries
Acute musculoskeletal (MSK) injuries, including strains, sprains or contusions, are a common reason patients seek emergency care. Pain control is an essential component of treatment.
- Conditions
- Pain, Opiate, Emergency
- Trial name
- NCT02720315
- Testing
- Intensive cryotherapy
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Stanford University
Musculoskeletal Pain, Analgesia
Intramuscular Ketorolac at Two Single-Dose Regimens
The purpose of this study was to evaluate a single 15 mg intramuscular (IM) dose of ketorolac for analgesic non-inferiority versus a single 60 mg IM dose for the treatment of acute MSK pain in a military emergency department (ED)…
- Conditions
- Musculoskeletal Pain, Analgesia, Adverse Event
- Trial name
- NCT04763876
- Testing
- Ketorolac Injection 15 mg, Ketorolac Injection 60 mg
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- William Beaumont Army Medical Center
Emergency Service, Hospital, Child/Adolescent Problem
A RCT of a Combination of Analgesics for Pain Management in Children With a Suspected Fracture
MSK-I is the most common cause for ED visits for children with pain, with a child's risk of sustaining a fracture ranging from 27-42% by the age of 16 years.
- Conditions
- Emergency Service, Hospital, Child/Adolescent Problem, Acute Pain, Fentanyl
- Trial name
- CAST (NCT02985177)
- Testing
- INF2.0 + IBU, INF1.0 + IBU
- Where
- 3 sites in Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Chronic Musculoskeletal Disease, Chronic Pain, Widespread
Effects of Acute Exercise on Pain and Human Movement
The aim of this research project is to evaluate the effect of an acute exercise intervention on pain intensity and movement control.
- Trial name
- eMOVE (NCT03882333)
- Testing
- Acute exercise
- Where
- Sweden
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Dalarna University
Gout, Acute Gout Flare
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral ABP-745 Administration in Healthy Volunteers
A randomized, double-blind, placebo-controlled, dose-escalation study will be conducted in healthy volunteers. This study will evaluate the safety, tolerability, and pharmacokinetics (PK) of ABP-745 following single (Part 1) and…
- Conditions
- Gout, Acute Gout Flare, Gout Flares
- Trial name
- ABP-745 (NCT06258213)
- Testing
- ABP-745
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Atom Therapeutics Co., Ltd
Musculoskeletal Chest Pain, Non-cardiac Chest Pain
Treatment Study Comparing Manual Treatment or Advice in Acute, Musculoskeletal Chest Pain
Acute chest pain is a common cause of hospital admission. Active approaches are directed towards diagnosis and treatment of potentially life threatening conditions, especially acute coronary syndrome and coronary artery disease.
- Conditions
- Musculoskeletal Chest Pain, Non-cardiac Chest Pain, Undiagnosed Chest Pain
- Trial name
- CARPA (NCT00462241)
- Testing
- chiropractic treatment, Self-management
- Where
- Denmark
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Clinical Locomotion Science
Musculoskeletal Pain
Emergency Department Acupuncture for Acute Musculoskeletal Pain Management
The purpose of this project is to determine the feasibility, acceptability and effectiveness of acupuncture in the Emergency Department (ED) for treating acute musculoskeletal pain.
- Trial name
- NCT04290741
- Testing
- Auricular (Battlefield) Acupuncture, Peripheral Acupuncture
- Where
- United States
- Volunteers
- 599 people, healthy volunteers welcome
- Sponsor
- Duke University
Muscle Soreness, Muscle Weakness
Lumbosacral Muscle Sensitivity & Pressure Pain Threshold After Kettlebell Swings
The primary purpose of the study is to assess the muscle contractility and sensitivity of lumbar erector spinae, biceps femoris, and gluteus maximus short-term response to Tabata kettlebell swing protocol.
- Conditions
- Muscle Soreness, Muscle Weakness, Muscle Tenderness
- Trial name
- NCT05607212
- Testing
- Kettlebell Swing, Isometric Hold, Control
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Acute Pain, Anesthesia
Effectiveness of Retrolaminar Block in Lumbar Spine Fusion With Multimodal Analgesia
This randomized, blinded, controlled clinical trial aims to evaluate the effectiveness of ultrasound-guided retrolaminar block in reducing postoperative opioid consumption in patients undergoing lumbar spine fusion surgery under…
- Conditions
- Acute Pain, Anesthesia, Lumbar Spine Disease
- Trial name
- RBLUF (NCT07291388)
- Testing
- retrolaminar block
- Where
- Chile
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Pain, Acute, Muscle Tone Abnormalities
Cognitive and Motor Benefits of Standing
Upright-working has been proven to benefit health by combating the negative effects of physical inactivity. However, long-term commitment to static standing regimens may be limited due to symptoms of musculoskeletal fatigue that…
- Conditions
- Pain, Acute, Muscle Tone Abnormalities, Work-Related Condition, Sensory Deficit
- Trial name
- KOGIS (NCT03944564)
- Testing
- Sitting, Static standing, Dynamic standing
- Where
- Slovenia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Science and Research Centre Koper
Neck Pain, Low Back Pain
Study to Demonstrate That Muscle Pattern Recognition (MPR) is an Effective Evaluation Tool for Musculoskeletal Neck or Back Pain
The investigators hypothesize that non able-bodied participants with reported acute, sub-acute, or chronic symptoms of neck or back pain of a musculoskeletal origin will have magnetic resonance imaging (MRI), X-ray and blood…
- Trial name
- NCT00134225
- Testing
- Muscle Pattern Recognition (MPR)
- Where
- 4 sites in United States, Canada
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- iTech Medical, Inc.
Fibromyalgia, Pain, Chronic
Psychobiological Mechanisms Underlying Chronic Pain
Pain is a powerful motivator of behavior and it is more than the perception of nociceptive input. It is a complex experience that comprises different components: sensory discriminative, emotional-motivational and cognitive…
- Conditions
- Fibromyalgia, Pain, Chronic, Chronic Pain, Widespread
- Trial name
- NCT04674670
- Testing
- Bromocriptine Mesylate Capsules, Amisulpride 400 MG
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- susanne becker
Insomnia, Healthy Adult
The Effect of Different rTMS Interventions on Acute Experimental Muscular Pain in Individuals Comorbid With Insomnia
Insomnia exacerbates pain sensitivity and impairs physiological recovery from acute musculoskeletal pain. Repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising non-invasive neuromodulation intervention to…
- Conditions
- Insomnia, Healthy Adult, Exercise Induced Muscle Damage, Pain Sensitivity
- Trial name
- NCT07827677
- Testing
- Repetitive transcranial magnetic stimulation (rTMS) on L M1, Repetitive transcranial magnetic stimulation (rTMS) on R DLPFC
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University