Clinical trials: Acute Musculoskeletal Pain
Asthma, Atrial Fibrillation
The Living With a Long-Term Condition Study
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs).
- Conditions
- Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders
- Trial name
- LTC (NCT06072287)
- Testing
- Living with LTC Questionnaire
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
RADICULAR PAIN
Efficacy of Intravenous Dexamethasone for Acute Disc Herniation-Induced Sciatica
Acute low back pain is one of the most common reasons for all physician visits(1). Phospholipase A2 (PLA2), a potent inflammatory mediator, has demonstrated to be released by discs following injury(4).
- Trial name
- NCT00516009
- Testing
- DEXAMETHASONE
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Ziv Hospital
Coxarthrosis, Pain, Postoperative
Lumbar ESPB in Hip Replacement Surgery
In this study, continuous erector spinae plane block (ESPB) will be compared to continuous epidural analgesia in patients undergoing elective hip replacement surgery.
- Conditions
- Coxarthrosis, Pain, Postoperative, Pain, Acute, Pain, Chronic
- Trial name
- ESPB_HIP (NCT06282666)
- Testing
- Spinal anesthesia, lumbar erector spinae plane block, Epidural analgesia
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Lublin
Pain
HKT-500 in Adult Patients With Shoulder Pain
The objective of this study is to determine the efficacy of HKT-500 in subjects with acute shoulder pain
- Trial name
- Pain (NCT00680472)
- Testing
- HKT-500 Ketoprofen Topical Patch
- Where
- 35 sites in United States
- Volunteers
- 368 people
- Sponsor
- Hisamitsu Pharmaceutical Co., Inc.
LIPIN1 Deficiency
Acute Rhabdomyolysis and Muscle Pain Associated With Mutations in the LPIN1 Gene - A Retrospective Study Describing the Safety and Efficacy of Hydroxychloroquine Sulfate Given on a Compassionate Basis to Patients Suffering From Lipin-1 Deficiency
Lipin-1 deficiencies are responsible for severe rhabdomyolysis and muscle pain in childhood. A specific treatment does not exist.
- Trial name
- LIPIN-1-METAB (NCT04007562)
- Testing
- Hydroxychloroquine Sulfate
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Musculoskeletal Pain - Acute and Subacute Conditions, Exercise (EX)
Exercise, Pain Beliefs, and Activity Patterns in Musculoskeletal Pain
This observational study aims to investigate the relationship between exercise benefits and barriers, pain beliefs, and activity patterns in individuals experiencing musculoskeletal pain.
- Conditions
- Musculoskeletal Pain - Acute and Subacute Conditions, Exercise (EX), Beliefs, Activity Level
- Trial name
- EPAP (NCT07528807)
- Testing
- This is an observational study. No interventions or treatments are administered.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Postoperative Pain
Prediction of Acute Postoperative Pain and Analgesic Consumption
Pain is an expected part of surgical recovery but effective pain management remains challenging. The high variability in postoperative pain experience and analgesic treatment response between patients is part of the challenge.
- Trial name
- MIRPEX-3 (NCT02230865)
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Kasper Grosen
Juvenile; Scoliosis, Scoliosis Idiopathic
Studying Melatonin and Recovery in Teens
The goal of this feasibility clinical trial is to learn if melatonin can help teens having major musculoskeletal surgery by promoting healthy sleep.
- Conditions
- Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital
- Trial name
- SurgerySMART (NCT06093477)
- Testing
- Fast-Dissolve Melatonin Pill
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Osteopenia, Osteoporosis
FREE Study - Fracture Reduction Evaluation
The primary objective of this study is to compare the effectiveness of standard medical therapy alone to kyphoplasty using the KyphX system for the treatment of acute vertebral body compression fractures.
- Conditions
- Osteopenia, Osteoporosis, Multiple Myeloma, Bone Neoplasms
- Trial name
- NCT00211211
- Testing
- Balloon Kyphoplasty
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Medtronic Spine LLC
Musculoskeletal Pain
Comparison of Efficacy of Intravenous Paracetamol and Dexketoprofen for Acute Traumatic Musculoskeletal Pain
Currently, paracetamol and nonsteroidal antiinflammatory drugs are widely used by emergency physicians in Turkey for the treatment of patients with acute traumatic musculoskeletal pain.
- Trial name
- NCT03428503
- Testing
- Paracetamol, Dexketoprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Pamukkale University
Post-operative Pain, Acute, Opioid Use, Unspecified
Patient Centered Post-Op Pain Management Software Tool Interventional Study Verses Standard of Care
The goal of this clinical trial is to learn if the Pain Coach App will result in less opioids being prescribed to and used by patients undergoing Shoulder/Hip/Knee Arthroplasty surgery while maintaining the same or better pain…
- Conditions
- Post-operative Pain, Acute, Opioid Use, Unspecified, Arthroplasty Complications, Knee Osteoarthritis
- Trial name
- NCT06469177
- Testing
- Pain Coach App
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Subacromial Impingement Syndrome, Glenohumeral Internal Rotation Deficit
The Acute Effects of Different Stretching Methods in Individuals With Subacromial Impingement Syndrome
The purpose of this study is to investigate and compare the acute effects of isolytic and static stretching training in individuals having subacromial impingement syndrome with glenohumeral internal rotation deficit.
- Trial name
- NCT03246867
- Testing
- Isolytic stretching group, Static stretching group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Dokuz Eylul University
Temporomandibular Disorders (TMD), Acute Apical Periodontitis of Pulpal Origin
The Role of Root Canal Treatment in Alleviating Endodontic Pain-Induced Asymmetry and Restoring Muscle Balance
The study hypothesizes that masticatory laterality caused by acute apical periodontitis pain result in muscle asymmetry. Furthermore, it posits that successful root canal treatment, by restoring normal bilateral chewing function…
- Trial name
- NCT06853028
- Testing
- ultrasound measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Cukurova University
Spine Health, Spine Injuries and Disorders
Occupational Exposure to Whole Body Vibration Among U.S. Military Veterans: Acute and Chronic Contributions to Musculoskeletal Disorders and Spine-Area Pain
Significance to VA: There is a lack of prospective longitudinal studies investigating the relationship between risk factors to Veterans and development and progression of musculoskeletal (MSK) spine injury and pain.
- Conditions
- Spine Health, Spine Injuries and Disorders, Spine Degeneration, Whole Body Vibration
- Trial name
- NCT07367139
- Testing
- Water
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Milwaukee VA Medical Center
Osteoarthritis
Does Optimal Control of Pre-operative Chronic and Acute Pain Predict Improved Function After Orthopedic Surgery?
Despite the development of new pain medications, the prevalence of persistent postoperative pain (for more than three to six months) remains alarmingly high.
- Trial name
- NCT00581685
- Testing
- Pregabalin, Celecoxib
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Iontophoresis, Ultrasound Therapy; Complications
Effect of Iontophoresis vs. Ultrasound and Iontophoresis in Plantar Fasciitis". Plantar Fasciitis"
Plantar fasciitis is inflammation of plantar fascia.The main symptom of plantar fasciitis manifests itself as localized pain in the inner area of the foot and increases in intensity after long periods of standing or resting.
- Conditions
- Iontophoresis, Ultrasound Therapy; Complications, Fasciitis, Plantar, Pain, Acute
- Trial name
- NCT04917406
- Testing
- Application of lidocaine together with dexamethasone, Application of ultrasound as physical therapy
- Where
- Spain
- Volunteers
- 76 people
- Sponsor
- University of Seville
Pain, Acute, Pain, Joint
Preoperative Psychosocial Support for Postoperative Recovery and Health: Mechanistic Substudy
This was a single site, three-arm, parallel group randomized clinical trial that compared the effect of three preoperative psychosocial interventions on knee and hip replacement patients' preoperative pain intensity and…
- Conditions
- Pain, Acute, Pain, Joint, Pain
- Trial name
- NCT04520958
- Testing
- Mindfulness of Breath, Mindfulness of Pain, Cognitive-Behaviorally Based Pain Psychoeducation
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Utah
Postacute Sequelae of Sars-CoV-2, Post-Acute COVID-19 Syndrome
Transcutaneous Electrical Nerve Stimulation (TENS) in Patients With Postacute Sequelae of Sars-CoV-2
The purpose of the pilot study is to examine acceptability and proof of concept effectiveness of a wireless TENS technology to address PASC associated FM.
- Conditions
- Postacute Sequelae of Sars-CoV-2, Post-Acute COVID-19 Syndrome, Widespread Chronic Pain, Fatigue Syndrome, Chronic
- Trial name
- NCT05200858
- Testing
- TENS - high-dose, TENS - low-dose
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
Postoperative Pain, Acute, Shoulder Pain
Evaluating Intercostobrachial Nerve Block's Effect on Pain Control After Shoulder Replacement
Interscalene blocks are frequently performed to decrease postoperative pain after shoulder surgeries and are considered the gold standard for pain control after this type of surgery.
- Trial name
- NCT06042608
- Testing
- intercostobrachial nerve block
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Musculoskeletal Chest Pain, Non-cardiac Chest Pain
Treatment Study Comparing Manual Treatment or Advice in Acute, Musculoskeletal Chest Pain
Acute chest pain is a common cause of hospital admission. Active approaches are directed towards diagnosis and treatment of potentially life threatening conditions, especially acute coronary syndrome and coronary artery disease.
- Conditions
- Musculoskeletal Chest Pain, Non-cardiac Chest Pain, Undiagnosed Chest Pain
- Trial name
- CARPA (NCT00462241)
- Testing
- chiropractic treatment, Self-management
- Where
- Denmark
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Clinical Locomotion Science