Clinical trials: Acute Myocardial Infarction, completed
ST-elevation Myocardial Infarction, Multivessel Coronary Disease
MULTivessel Immediate Versus STAged RevaScularization in Acute Myocardial Infarction -The MULTISTARS AMI Trial
The primary objective of the trial is to compare, in patients presenting with ST segment elevation myocardial infarction (STEMI) and multi-vessel disease (MVD), the safety and efficacy of immediate complete revascularization of…
- Trial name
- MULTISTARS AMI (NCT03135275)
- Testing
- Staged complete PCI, Immediate complete PCI, Synergy™ stent
- Where
- Switzerland
- Volunteers
- 840 people
- Sponsor
- University of Zurich
Acute Myocardial Infarction
The Effects of Facilitated Percutaeous Coronary Intervention in Acute Myocardial Infarction
The purpose of this study to investigate whether the administration of high-dose tirofiban before primary PCI could reduce myocardial infarct size, using analysis of contrast-enhanced magnetic resonance imaging.
- Trial name
- NCT00611169
- Testing
- tirofiban
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Acute Coronary Syndrome
The Stabilization Of pLaques usIng Darapladib-Thrombolysis In Myocardial Infarction 52 Trial
This study will test whether darapladib can safely lower the chances of having a cardiovascular event (such as a heart attack or urgent coronary revascularization (e.g.
- Trial name
- SOLID-TIMI 52 (NCT01000727)
- Testing
- Darapladib 160 mg, Standard Therapy
- Where
- 914 sites in United States, Argentina and 34 more
- Volunteers
- 13,026 people
- Sponsor
- GlaxoSmithKline
Acute ST Segment Elevation Myocardial Infarction
Safety and Efficacy of TCD-10023 (Ultimaster) Drug-eluting Stent in STEMI Patients - MASTER Study
The aim of the study is to demonstrate the safety and efficacy of the TCD-10023 (Ultimaster) sirolimus eluting stent in patients with acute ST-elevation myocardial infarction (STEMI), by proving superiority with respect to…
- Trial name
- MASTER (NCT02828683)
- Testing
- PCI in patients with ST-elevation myocardial infarction
- Where
- 13 sites in Brazil, Italy and 3 more
- Volunteers
- 500 people
- Sponsor
- Terumo Europe N.V.
Myocardial Infarction
MCC-135 as Adjunct Therapy to Primary Percutaneous Coronary Intervention in ST-Segment Elevation Acute Myocardial Infarction Patients
This study is a multicenter, randomized, double-blind, placebo-controlled clinical trial. The primary objectives of this study are to examine the safety, tolerability, and efficacy of intravenous MCC-135 in limiting final infarct…
- Trial name
- NCT00078013
- Testing
- MCC-135
- Where
- United States
- Volunteers
- 414 people
- Sponsor
- Tanabe Pharma Corporation
Myocardial Infarction
Trial to Compare the Efficacy and Safety of a Single Bolus of TNK-tPA (Tenecteplase, Metalyse®) With Accelerated Infusion of Rt-PA (Alteplase, Actilyse®) in Asian Patients With Acute Myocardial Infarction
The objective of this trial was to compare the efficacy and safety of a single bolus of TNK-tPA (tenecteplase, Metalyse®) compared with rt-PA (alteplase, Actilyse®) in Asian patients.
- Trial name
- NCT00148460
- Testing
- TNK-tPA, rt-PA
- Where
- 18 sites in China, Hong Kong and 1 more
- Volunteers
- 270 people
- Sponsor
- Boehringer Ingelheim
Chest Pain
Investigating the Role of Active Versus Chronic Coronary Artery Calcification on Acute Myocardial Infarct
The investigator aims to determine the feasibility of understanding the process of active versus chronic calcification using Na-F PET scan and contrast CT scan of the heart.
- Trial name
- Active-AMI (NCT03712020)
- Volunteers
- 15 people
- Sponsor
- National Heart Centre Singapore
Acute Coronary Syndrome, Myocardial Infarction
Magnetocardiography Using a Novel Analysis System (Cardioflux) in the Evaluation of Emergency Department Observation Unit Chest Pain Patients
Genetesis is a cardiac diagnostics company which presents a novel magnetocardiogram (MCG) analysis system called CardioFlux. This investigation presents a new, noninvasive diagnostic option to use MCG for rapid diagnosis of acute…
- Trial name
- NCT03255772
- Testing
- Magnetocardiography
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Genetesis Inc.
Angina Pectoris, Unstable Angina
Pilot Study of Hemoglobin Based Oxygen Therapeutics in Elective Coronary Revascularization
The purpose of this study is to assess the safety and feasibility of a novel oxygen carrying solution, HBOC-201, in the setting of PCI for Acute Coronary Syndromes from randomization til hospital discharge.
- Conditions
- Angina Pectoris, Unstable Angina, Myocardial Infarction
- Trial name
- NCT00317512
- Testing
- Percutaneous Coronary Revascularization, Hemoglobin-Based Oxygen Carrier-201 (HBOC-201), Voluven
- Where
- 6 sites in Belgium, Germany and 1 more
- Volunteers
- 45 people
- Sponsor
- Biopure Corporation
NSTEMI - Non-ST Segment Elevation MI
TIII Over TI in Subjects With Myocardial Infarction
Study was performed to identify ECG criteria for unmasking of subjects with NSTEMI at elevated risk.
- Trial name
- T-infarction (NCT03057093)
- Testing
- Non interventional study
- Volunteers
- 903 people
- Sponsor
- University of Cologne
Acute Myocardial Infarction
Validation of a High-risk Versus Low-risk Referral Model in Suspected Acute Coronary Syndrome
In Emergency Departments patients admitted with chest pain may suffer from non-significant to lifethreatening conditions. The aim of the present study is to develop and validate a referral model in chest pain patients which…
- Trial name
- NCT01747421
- Where
- Denmark
- Volunteers
- 495 people
- Sponsor
- University of Southern Denmark
Left Ventricular Dysfunction
Use of Adult Autologous Stem Cells in Treating People 2 to 3 Weeks After Having a Heart Attack (The Late TIME Study)
More than 1 million Americans suffer heart attacks each year. Although current treatments are able to stabilize the condition of the heart, none is able to restore heart function as it was prior to the heart attack.
- Trial name
- NCT00684060
- Testing
- Adult stem cells
- Where
- 5 sites in United States
- Volunteers
- 87 people
- Sponsor
- The University of Texas Health Science Center, Houston
Acute Coronary Syndrome
An Intervention to Reduce Prehospital Delay to Treatment in Acute Coronary Syndrome
This study was conducted to test whether a focused education and counseling intervention delivered by a nurse will decrease time of delay in seeking treatment for the signs and symptoms of acute coronary syndrome (i.e., heart…
- Trial name
- PROMOTION (NCT00734760)
- Testing
- education
- Volunteers
- 3,522 people
- Sponsor
- University of California, San Francisco
Myocardial Infarction
Optical Coherence Tomography in Patients With Acute Myocardial Infarction and Nonobstructive Coronary Artery Disease
The purpose of this study is to evaluate the prevalence and morphological features of coronary plaques by means of OCT in patients with acute myocardial infarction but without any significant coronary stenosis at coronary…
- Trial name
- SOFT-MI (NCT02783963)
- Testing
- OCT and CMR imaging
- Where
- Poland
- Volunteers
- 38 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Acute Myocardial Infarction
Sweat Analysis as Prognosticator After Heart Attack
This study characterizes non-invasive body inflammation response in sweat and blood of patients suffering from acute myocardial infarction and explores the potential of non-invasive sweat analysis a an innovative approach for…
- Trial name
- SWEATHEART (NCT05843006)
- Testing
- Examination and analysis of sweat and blood samples at baseline and at follow up, Examination and analysis of sweat and blood samples at baseline
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Region Örebro County
Myocardial Infarction
Cardiovascular Clinical Project to Evaluate the Regenerative Capacity of CardioCell in Patients With Acute Myocardial Infarction (AMI)
The main objective of the CIRCULATE project is to compare the clinical outcomes of CardioCell administration in treatment of ischemic damages of cardiovascular system with control group, who will be treated by the administration…
- Trial name
- NCT03404063
- Testing
- Cardiac Drug
- Where
- 2 sites in Poland
- Volunteers
- 105 people
- Sponsor
- John Paul II Hospital, Krakow
Acute Myocardial Infarction
Effects of Nitric Oxide for Inhalation in Myocardial Infarction Size
The purpose of this study is to determine the effects of Nitric Oxide for Inhalation on Myocardial Infarction Size.
- Trial name
- NOMI (NCT01398384)
- Testing
- Nitric Oxide, MI size at 48-72 hours
- Where
- 4 sites in Belgium, Hungary and 1 more
- Volunteers
- 250 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Acute Myocardial Infarction, STEMI
Delayed Educational Reminders in Acute Myocardial Infarction (MI)
ST segment elevation myocardial infarction (STEMI) is a common presentation of heart attack constituting approximately 30% of all cases.
- Trial name
- DERLA-STEMI (NCT01325116)
- Testing
- Educational Reminder
- Where
- Canada
- Volunteers
- 852 people
- Sponsor
- Hamilton Health Sciences Corporation
Acute Myocardial Infarction, Pacing Therapy
Post-Myocardial Infarction Remodeling Prevention Therapy
The purpose of this study is to demonstrate the feasibility of pacing as a therapy to prevent adverse remodeling of the myocardium following an acute myocardial infarction (MI) in patients at highest risk for adverse myocardial…
- Conditions
- Acute Myocardial Infarction, Pacing Therapy, Cardiac Remodeling, Heart Failure
- Trial name
- PRomPT (NCT01213251)
- Testing
- Single Site Pacing, Dual Site Pacing
- Where
- 26 sites in United States, Denmark and 5 more
- Volunteers
- 129 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Myocardial Infarction
Surveillance of Patients With Suspected Acute Myocardial Infarction That Receive Early Inhospital Thrombolysis With Metalyse
Obtaining data on efficacy (e.g. complete ST-segment resolution) depending on the time of treatment initiation and safety of prehospital and early hospital thrombolysis with Metalyse® in a real life setting outside clinical…
- Trial name
- NCT02194153
- Testing
- Metalyse weight-adjusted
- Volunteers
- 351 people
- Sponsor
- Boehringer Ingelheim