Clinical trials: Acute Myocardial Infarction, completed
Acute Respiratory Distress Syndrome, Cardiogenic Shock
Study of Immunity Dysfunction Induced by Extracorporeal Assistance (ECMO / ECLS)
Study of immunosuppression biomarkers in patients with ARDS or cardiogenic shock with ECMO / ECLS, compared to patients with ARDS or cardiogenic shock without ECMO / ECLS
- Trial name
- IMPEC (NCT03262155)
- Testing
- Blood test
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Rennes University Hospital
Myocardial Infarction, Acute Coronary Syndrome
Acute Coronary Syndrome in Patients With COVID-19
The aim of this study was to find a clinical or laboratory parameter, that would help in distinguishing between COVID-19 patients with myocardial infarction (MI), who have an infarct-related artery (IRA) and therefore, require…
- Conditions
- Myocardial Infarction, Acute Coronary Syndrome, COVID-19, Myocardium; Injury
- Trial name
- ACS-COVID (NCT05732597)
- Testing
- Coronary angiography
- Where
- Bulgaria
- Volunteers
- 26 people
- Sponsor
- Bulgarian Cardiac Institute
Acute Coronary Syndrome, Non-ST-Elevation Myocardial Infarction
Risk Stratification of Non ST Elevation ACS With Computed Tomographic Angiography (REACT)
The purpose of this project is to examine the effectiveness of computed tomographic angiography (CTA) in patients with non-ST elevation acute coronary syndrome (NSTE-ACS).
- Conditions
- Acute Coronary Syndrome, Non-ST-Elevation Myocardial Infarction, Unstable Angina
- Trial name
- NCT00449826
- Testing
- Computed Tomographic Angiography
- Where
- Canada
- Volunteers
- 107 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Cardiogenic Shock, Acute; Myocardial Infarction, Complications
Carolinas Cardiogenic Shock Initiative
To determine if deferred or delayed implantation of Impella device based on shock severity index is non-inferior with respect to 1 month and 1 year mortality compared to standard clinical protocols that do not differentiate based…
- Trial name
- CCSI (NCT04985708)
- Testing
- data collection of clinically available procedures
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Wake Forest University Health Sciences
Acute Myocardial Infarction, Diabetes Mellitus
Coronary Flow Reserve and Glucometabolic State
Diabetes mellitus is a major risk factor for the development of ischemic heart disease, and patients with diabetes mellitus have a worse outcome following an acute myocardial infarction than non-diabetic patients.
- Conditions
- Acute Myocardial Infarction, Diabetes Mellitus, Prediabetes
- Trial name
- NCT00845468
- Where
- Denmark
- Volunteers
- 190 people
- Sponsor
- Medicinsk Forsknings Afdeling
Angina Pectoris, Angina, Stable
Intracoronary Thrombus Detection by Magnetic Resonance Imaging
This study involves the use of Magnetic Resonance Imaging (MRI) to determine whether blood clots can be identified within the blood vessels supplying blood to the heart in patients with angina and who have recently suffered a…
- Conditions
- Angina Pectoris, Angina, Stable, Angina, Unstable, Myocardial Infarction
- Trial name
- NCT02776657
- Testing
- Magnetic Resonance Imaging, Optical Coherence Tomography, Invasive Coronary Angiography
- Volunteers
- 40 people
- Sponsor
- University of Edinburgh
Acute Myocardial Infarction, Coronary Syndrome
Antiplatelet Therapy Following Stent Implantation
Coronary artery stents, particularly drug-eluting stents (DES), are used in the majority of patients who undergo percutaneous coronary intervention (PCI) to improve symptoms in patients with obstructive coronary artery disease.
- Conditions
- Acute Myocardial Infarction, Coronary Syndrome, Angina, Unstable
- Trial name
- Anti-Clot (NCT02051361)
- Where
- Greece
- Volunteers
- 900 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Coronary Stenosis, Periodontal Diseases
Periodontal Disease, Inflammation and Acute Coronary Syndromes
Recent studies have shown that the systemic inflammation caused by periodontal disease (PD) can determine important changes in the coronary arteries, favoring atherosclerosis progression and development of acute coronary…
- Conditions
- Coronary Stenosis, Periodontal Diseases, Acute Coronary Syndrome, Non-ST Elevation Myocardial Infarction
- Trial name
- ATHERODENT (NCT03395041)
- Testing
- cardiac imaging tests
- Where
- Romania
- Volunteers
- 149 people
- Sponsor
- Cardio Med Medical Center
Cardiovascular Diseases, Acute Myocardial Infarction
Biomarkers Predicting Acute Myocardial Infraction in Patients Without Standard Modifiable Risk Factors
Coronary heart disease (CHD) is the leading cause of mortality worldwide. Every year, millions of people suffer its most adverse manifestation, an acute myocardial infraction (AMI).
- Conditions
- Cardiovascular Diseases, Acute Myocardial Infarction, Acute Coronary Syndrome, Metabolic Disturbance
- Trial name
- BeyondSMuRFs (NCT05535582)
- Testing
- Investigation of clinical, laboratory and imaging profile
- Where
- Greece
- Volunteers
- 1,000 people
- Sponsor
- Aristotle University Of Thessaloniki
Myocardial Infarction, Acute Coronary Syndrome
Diagnostic Accuracy of Electrocardiogram for Acute Coronary Occlusion Resulting in Myocardial Infarction
The decision of emergency reperfusion of a suspected acute coronary artery occlusion by means of percutaneous coronary intervention or intravenous thrombolytics depends on the presence of a certain amount of ST-segment elevation…
- Conditions
- Myocardial Infarction, Acute Coronary Syndrome, Coronary Artery Disease
- Trial name
- DIFOCCULT (NCT04022668)
- Testing
- Coronary angiogram
- Where
- Turkey (Türkiye)
- Volunteers
- 3,000 people
- Sponsor
- Yeditepe University
Myocardial Infarction
Impact Of Eplerenone On Cardiovascular Outcomes In Patients Post Myocardial Infarction
Administration of eplerenone within 24 hours of onset of symptoms of myocardial infarction, in patients without heart failure, reduces cardiovascular mortality / morbidity.
- Trial name
- REMINDER (NCT01176968)
- Testing
- Eplerenone
- Where
- 75 sites in Canada, Czechia and 9 more
- Volunteers
- 1,012 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Acute Myocardial Infarction (AMI)
Angiography Derived Index of Microcirculatory Resistance in Patients With Acute Myocardial Infarction
Coronary microcirculatory dysfunction has been known to be prevalent even after successful revascularization of acute myocardial infarction (AMI) patients, and has been shown to be associated with poor prognosis.
- Trial name
- NCT05696379
- Testing
- Angiography derived index of micro-circulatory resistance (Angio-IMR)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Coronary Syndrome, Myocardial Infarction
Magnetocardiography Using a Novel Analysis System (Cardioflux) in the Evaluation of Emergency Department Observation Unit Chest Pain Patients
Genetesis is a cardiac diagnostics company which presents a novel magnetocardiogram (MCG) analysis system called CardioFlux. This investigation presents a new, noninvasive diagnostic option to use MCG for rapid diagnosis of acute…
- Trial name
- NCT03255772
- Testing
- Magnetocardiography
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Genetesis Inc.
ST-Elevation Myocardial Infarction
Colchicine's Efficacy in MI Patients: Comparing PCI and Non-Reperfusion Approaches
This study investigates the effect of Colchicine in preventing heart structure changes following ST-segment elevation myocardial infarction.
- Trial name
- NCT06426537
- Testing
- Colchicine 0.5 MG Oral Tablet
- Where
- Indonesia
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Brawijaya
Melatonin, Myocardial Infarction
Plasma Melatonin AND Mortality After Acute Myocardial Infarction
Pre-clinical and clinical studies have demonstrated that melatonin has cardio-protection effects. Melatonin has anti-inflammatory, antioxidant, antihypertensive, antithrombotic and antilipaemic properties, which plays important…
- Trial name
- NCT03230630
- Testing
- plasma melatonin levels
- Volunteers
- 732 people
- Sponsor
- Chinese PLA General Hospital
Acute Myocardial Infarction
Stem Cells in Myocardial Infarction
The purpose of this trial is to investigate the effect of treatment with granulocyte-colony stimulating factor (G-CSF) bone marrow stimulation on circulating stem cells' ability to develop new blood vessels in the myocardium…
- Trial name
- NCT00135928
- Testing
- Granulocyte Colony Stimulating Factor G-CSF (Neupogen®)
- Where
- Denmark
- Volunteers
- 78 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Myocardial Infarction, STEMI
Delayed Educational Reminders in Acute Myocardial Infarction (MI)
ST segment elevation myocardial infarction (STEMI) is a common presentation of heart attack constituting approximately 30% of all cases.
- Trial name
- DERLA-STEMI (NCT01325116)
- Testing
- Educational Reminder
- Where
- Canada
- Volunteers
- 852 people
- Sponsor
- Hamilton Health Sciences Corporation
Acute Myocardial Infarction
China PEACE II: Quality Improvement for Acute Myocardial Infarction
This study aims to develop quality improvement strategies and relevant tools focusing on reperfusion therapy in patients with STEMI, and to evaluate their effectiveness via a hospital-level cluster randomized clinical trial…
- Trial name
- PEACE-QI-AMI (NCT02322944)
- Testing
- Quality improvement strategies and tools, Process optimization
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- China National Center for Cardiovascular Diseases
Myocardial Infarction, Acute Coronary Syndrome
Study to Evaluate the Care Process and the Quality of STEMI Care
Cardiovascular diseases, and more precisely patients with ST - elevated myocardial infarction are globally responsible for a large number of hospitalizations and deaths.
- Trial name
- CP4ACS (NCT02961777)
- Testing
- implementation of care pathway
- Volunteers
- 640 people
- Sponsor
- European Pathway Association
Coronary Stenosis, Acute Coronary Syndrome
Coronary Plaque Geometry and Acute Coronary Syndromes
The aim of GEOMETRY study is to investigate the correlation between coronary plaque geometric modifications and lesion vulnerability in patients with suspected coronary artery disease referred for cardiac computed tomography…
- Conditions
- Coronary Stenosis, Acute Coronary Syndrome, Acute Myocardial Infarction, Atherosclerosis
- Trial name
- NCT03702764
- Testing
- CCTA
- Where
- Romania
- Volunteers
- 1,000 people
- Sponsor
- Cardio Med Medical Center