Clinical trials: Acute Myocardial Infarction, completed
Acute Myocardial Infarction, Cardiogenic Shock
Extracorporeal Life Support in Cardiogenic Shock
The aim of the study is to examine whether treatment with extracorporeal life support (ECLS) in addition to revascularization with percutaneous coronary intervention (PCI) or alternatively coronary artery bypass grafting (CABG)…
- Trial name
- ECLS-SHOCK (NCT03637205)
- Testing
- ECLS insertion, Revascularisation and optimal medical treatment
- Where
- 46 sites in Germany, Slovenia
- Volunteers
- 420 people
- Sponsor
- Helios Health Institute GmbH
Infarction, Myocardial
Efficacy Of Eptifibatide Compared To Abciximab In Primary Percutaneous Coronary Intervention (PCI) For Acute ST Elevation Myocardial Infarction (STEMI)
Multinational, multicentre, randomised, prospective, open, parallel group study directly comparing two glycoprotein-IIb/IIIa inhibitors, abciximab and eptifibatide, added early to standard treatment before primary PCI of STEMI…
- Trial name
- NCT00426751
- Testing
- Abciximab, Eptifibatide
- Where
- 24 sites in France, Germany
- Volunteers
- 429 people
- Sponsor
- GlaxoSmithKline
Acute Coronary Syndrome
A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome
The purpose of this study is to estimate the risk of bleeding with rivaroxaban, compared with acetylsalicylic acid (ASA), in addition to a single antiplatelet/ platelet adenosine diphosphate P2Y12 receptor antagonist (P2Y12…
- Trial name
- GEMINI ACS 1 (NCT02293395)
- Testing
- Acetylsalicylic acid, Rivaroxaban, Clopidogrel
- Where
- 259 sites in United States, Argentina and 18 more
- Volunteers
- 3,037 people
- Sponsor
- Janssen Research & Development, LLC
ST-elevation Myocardial Infarction
Standard (180mg) Versus Double (360mg) Loading Dose of Ticagrelor in Patients With ST-elevation Myocardial Infarction (STEMI), Undergoing Primary Percutaneous Coronary Intervention (PCI)
This is a multi-center, prospective, randomized, single-blind, investigator initiated, pharmacodynamic study of parallel design, performed at 3 institutions (Patras University Hospital; Evangelismos Athens General Hospital…
- Trial name
- NCT01575795
- Testing
- Ticagrelor
- Where
- Greece
- Volunteers
- 83 people
- Sponsor
- University of Patras
Acute Coronary Syndrome
Long-term Follow-up of Antithrombotic Management Patterns in Acute Coronary Syndrome Patients in Russia
EPICOR-RUS is a multi-centre, observational, prospective, longitudinal cohort study which will include patients, in a real-life setting, who are hospitalized for acute coronary syndrome (ACS) within 24 hours of symptom onset and…
- Trial name
- EPICOR-RUS (NCT01373957)
- Where
- 19 sites in Russia
- Volunteers
- 600 people
- Sponsor
- AstraZeneca
Acute Myocardial Infarction, STEMI
A Study of Acute Myocardial Infarction Using FDY-5301
The purpose of this study is to evaluate the safety, efficacy, and pharmacokinetics (PK) of three dose levels of FDY-5301 compared to placebo in STEMI patients undergoing PCI.
- Trial name
- NCT03470441
- Testing
- FDY-5301
- Where
- 23 sites in United States, Hungary and 2 more
- Volunteers
- 120 people
- Sponsor
- Faraday Pharmaceuticals, Inc.
Myocardial Infarction
CARDIOLITE-413: A Study for Patients Who Had a PCI for an Acute MI
The purpose of this clinical study is to learn if there are any changes in how blood gets to your heart muscle and if your heart size changed after your heart attack.
- Trial name
- NCT00162331
- Testing
- Technetium Tc99m Sestamibi
- Where
- 8 sites in United States, Brazil and 1 more
- Volunteers
- 74 people
- Sponsor
- Lantheus Medical Imaging
Myocardial Infarction, Diabete Type 2
Effects of Dapagliflozin on Inflammatory Factorslevel and Prognosis in Type 2 Diabetes With Acute Myocardial Infarction
Dapagliflozin is one of the SGLT-2 inhibiters. Recent clinical trials have demonstrated that SGLT-2 inhibitors are effective for treating heart failure.
- Conditions
- Myocardial Infarction, Diabete Type 2, Glucose Intolerance
- Trial name
- NCT05050500
- Testing
- Dapagliflozin 10mg/Tab, control group
- Where
- China
- Volunteers
- 143 people
- Sponsor
- Qingdao Central Hospital
Myocardial Infarction, Reperfusion Injury
Pilot Study of Edaravone to Treat Acute Myocardial Infarction
Early reperfusion therapy has improved the clinical outcomes of patients with acute myocardial infarction (AMI), but these benefits are limited in some patients by reperfusion injuries.
- Trial name
- NCT00265239
- Testing
- edaravone
- Where
- Japan
- Volunteers
- 104 people
- Sponsor
- Kumamoto University
ST-Elevation Myocardial Infarction
Colchicine's Efficacy in MI Patients: Comparing PCI and Non-Reperfusion Approaches
This study investigates the effect of Colchicine in preventing heart structure changes following ST-segment elevation myocardial infarction.
- Trial name
- NCT06426537
- Testing
- Colchicine 0.5 MG Oral Tablet
- Where
- Indonesia
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Brawijaya
Myocardial Infarction
Impact Of Eplerenone On Cardiovascular Outcomes In Patients Post Myocardial Infarction
Administration of eplerenone within 24 hours of onset of symptoms of myocardial infarction, in patients without heart failure, reduces cardiovascular mortality / morbidity.
- Trial name
- REMINDER (NCT01176968)
- Testing
- Eplerenone
- Where
- 75 sites in Canada, Czechia and 9 more
- Volunteers
- 1,012 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Acute Myocardial Infarction
The Relationship of Change of Dendritic Cells Fractalkine and P-selectin Patients With Acute Myocardial Infarction
This study evaluates the relationship of change of dendritic cells fractalkine and P-selectin in patients with acute myocardial infarction.
- Trial name
- NCT02896543
- Testing
- measurement
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Acute Myocardial Infarction
Transcutaneous Electrical Nerve Stimulation Improves Vascular Conductance After Coronary Artery Bypass Graft Surgery
The investigators will test the hypothesis that transcutaneous electrical nerve stimulation (TENS) may attenuate peripheral vasoconstriction and to improve blood flow redistribution during handgrip exercise in acute myocardial…
- Trial name
- TEBCABG (NCT01777659)
- Testing
- Transcutaneous electrical nerve stimulation
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Myocardial Infarction, STEMI
A Smartphone APPlication for the Transmission of ECGs in the Management of Patients Presenting With Suspected Heart Attacks in the Hamilton, Niagara, Haldimand, and Brant Area
The delivery of timely and appropriate care is crucial for patients with heart attacks. Blocked arteries need immediate intervention to restore blood flow.
- Trial name
- NCT05290389
- Testing
- SMART AMI APPLICATION
- Where
- 17 sites in Canada
- Volunteers
- 260 people
- Sponsor
- McMaster University
Acute Myocardial Infarction
Impact of Guidelines on Cardiovascular and Economic Outcomes With Focus on Lipid Lowering Drugs
Methods: All patients <75 years registered in the Swedish Secondary Prevention after Heart Intensive care Admission registry (SEPHIA), will be followed-up within one year post-myocardia infarction (MI).
- Trial name
- GuLLD (NCT02929550)
- Testing
- Well-controlled
- Volunteers
- 5,304 people
- Sponsor
- Karolinska Institutet
Acute Myocardial Infarction
Examining Heart Attacks in Young Women
Heart disease and heart attacks pose a serious health risk to young women, and women tend to experience less successful recoveries after a heart attack than men do.
- Trial name
- VIRGO (NCT00597922)
- Where
- 92 sites in United States
- Volunteers
- 2,985 people
- Sponsor
- Yale University
Myocardial Infarction, Heart Failure
Levosimendan in Acute Heart Failure Following Acute Myocardial Infarction.
The purpose of this study is to determine the safety and efficacy of a 24 hour infusion with levosimendan in patients with acute myocardial infarction and heart failure after acute percutaneous coronary intervention (PCI)…
- Conditions
- Myocardial Infarction, Heart Failure, Cardiogenic Shock
- Trial name
- NCT00324766
- Testing
- levosimendan
- Where
- Norway
- Volunteers
- 61 people
- Sponsor
- Oslo University Hospital
Chest Pain, Myocardial Infarction
ECG Methods for the Prompt Identification of Coronary Events
There is a clear need to develop improved tools to stratify risk in patients who seek emergency care for chest pain, one of the most common and potentially deadliest conditions encountered in acute care settings.
- Conditions
- Chest Pain, Myocardial Infarction, Myocardial Ischemia, Acute Coronary Syndrome
- Trial name
- EMPIRE (NCT04237688)
- Where
- United States
- Volunteers
- 6,000 people
- Sponsor
- University of Pittsburgh
Acute Myocardial Infarction, Adverse Event
Long-Term Follow-Up in Patients With Acute Myocardial Infarction Cohort
AMI Survivors who participated in the project "Construction and key technology research of the whole myocardial protection system for acute myocardial infarction" (project number 2016YFC1301100) and completed the 1-year visit…
- Trial name
- NCT05862103
- Testing
- Treatment Strategies
- Where
- 18 sites in China
- Volunteers
- 14,517 people
- Sponsor
- Yu Bo
Acute Myocardial Infarction
The Effectiveness of a TTM-based Multidisciplinary Collaboration on Cardiac Rehabilitation Outcomes in Patients With AMI
Cardiac rehabilitation (CR) has been shown to reduce morbidity and mortality in patients with acute myocardial infarction (AMI), however, the proportion of patients participating in and benefiting from cardiac rehabilitation (CR)…
- Trial name
- NCT07045220
- Testing
- TTMCR
- Where
- China
- Volunteers
- 86 people
- Sponsor
- RenJi Hospital