Clinical trials: Acute Myocardial Infarction, completed
Coronary Disease, Cardiovascular Disease
Gender Differences in the Development, Treatment and Prognosis of Coronary Disease: A CALIBER Study
The initial manifestation of symptomatic coronary disease can range from angina (or symptoms of angina), unheralded acute coronary syndrome (ACS), or unheralded coronary death.
- Trial name
- NCT01164371
- Volunteers
- 1,758,584 people
- Sponsor
- University College, London
Acute Myocardial Infarction
FATA: Randomized Study on Facilitated Angioplasty With Tirofiban or Abciximab
The elective("standard of care") treatment of ST - elevation acute myocardial infarction (STEMI) currently consists of primary angioplasty with stent implantation during administration of Abciximab, a inhibitor of GP IIb/IIIa…
- Trial name
- FATA (NCT00383136)
- Testing
- tirofiban high-bolus dose regimen, Abciximab
- Where
- 6 sites in Italy
- Volunteers
- 692 people
- Sponsor
- University of Bologna
Atrial Fibrillation, Myocardial Infarction, Acute
Prognostic Role of LA Strain in Acute Myocardial Infarction
This is a single-center retrospective observational study in which we consecutively selected patients diagnosed with acute myocardial infarction from September 2019 to March 2024 at the Affiliated Hospital of Xuzhou Medical…
- Conditions
- Atrial Fibrillation, Myocardial Infarction, Acute, Stroke Ischemic, Mortality
- Trial name
- CMR-MI (NCT06408636)
- Testing
- Cardiac MRI
- Where
- China
- Volunteers
- 780 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
ST-elevation Myocardial Infarction
Standard (180mg) Versus Double (360mg) Loading Dose of Ticagrelor in Patients With ST-elevation Myocardial Infarction (STEMI), Undergoing Primary Percutaneous Coronary Intervention (PCI)
This is a multi-center, prospective, randomized, single-blind, investigator initiated, pharmacodynamic study of parallel design, performed at 3 institutions (Patras University Hospital; Evangelismos Athens General Hospital…
- Trial name
- NCT01575795
- Testing
- Ticagrelor
- Where
- Greece
- Volunteers
- 83 people
- Sponsor
- University of Patras
Acute Myocardial Infarction With ST Elevation
Analysis of the Efficacy of Cardiac Ischemic Postconditioning With New Clinical End-points Using Novel Biomarkers
The aim of the present study was to investigate the efficacy of ischemic postconditioning in acute myocardial infarction patients. The safety of patients enrolled in the study was ensured during the entire study.
- Trial name
- NCT04824716
- Testing
- Postconditioning, Percutaneous coronary intervention
- Where
- 3 sites in Hungary
- Volunteers
- 100 people
- Sponsor
- Peter Ferdinandy
STEMI
Randomized Trial of a Quality Improvement Intervention to Decrease D2B Time in Primary PCI for AMI
The primary objective of this study is to assess whether an aggressive quality improvement intervention strategy will decrease time from hospital presentation to first balloon inflation in non-transfer patients with acute ST…
- Trial name
- RAPID-PCI (NCT01625104)
- Testing
- Non Intervention, Agressive Intervention Process Improvement Strategies
- Where
- United States
- Volunteers
- 882 people
- Sponsor
- University of Michigan
Acute Myocardial Infarction
PROTECT : Pacing to Protect Heart for Damage From Blocked Heart Vessel and From Re-opening Blocked Vessel(s)
To determine whether the application of ventricular pacing can protect the human heart from damage resulting from a myocardial infarction
- Trial name
- NCT00409604
- Testing
- Temporary RV VVI pacing
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Guidant Corporation
Acute Myocardial Infarction
Study to Gather Information About the Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following an Acute Heart Attack
The purpose of this study is to try to find the best dose of the new drug BAY 2433334 to give to participants and to look at how well BAY 2433334 works on top of a dual antiplatelet therapy (acetylsalicylic acid +/- clopidogrel)…
- Trial name
- PACIFIC-AMI (NCT04304534)
- Testing
- BAY2433334
- Where
- 160 sites in United States, Austria and 12 more
- Volunteers
- 1,601 people
- Sponsor
- Bayer
Renal Replacement Therapy, Renal Dialysis
A Clinical Trial of IntensiVE Dialysis
This study will assess clinical outcomes of extended weekly hours of haemodialysis (>= 24 hours per week) compared with standard hours of haemodialysis (<=18 hours/week) in people with ESKD.
- Conditions
- Renal Replacement Therapy, Renal Dialysis, End Stage Kidney Disease, End Stage Renal Disease
- Trial name
- ACTIVE (NCT00649298)
- Testing
- haemodialysis
- Where
- 40 sites in Australia, Canada and 2 more
- Volunteers
- 200 people
- Sponsor
- The George Institute
Acute Coronary Syndrome, Myocardial Infarction
Hepatocyte Growth Factor (HGF) Concentration in Myocardial Infarction
This is the continuation of previous study (registration number: NCT00844987) which revealed that hepatocyte growth factor (HGF) is a very early, good marker of myocardial injury and prognostic factor for post myocardial…
- Trial name
- NCT01233336
- Where
- Poland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
ACS - Acute Coronary Syndrome, NSTEMI - Non-ST Segment Elevation MI
MCG Discovery Study in Emergency Departments
This prospective discovery study is designed to demonstrate the feasibility of using an unshielded, mobile MCG device in an Emergency Department (ED) setting.
- Trial name
- NCT06095557
- Testing
- Sponsor MCG device
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- SB Technology, Inc.
Acute Coronary Syndrome, Myocardial Infarction, Acute
Heart Matters: The Effectiveness of Heart Health Education in Regions at Highest-risk.
The aim of the study is to evaluate whether providing a targeted heart health education campaign to regions at high risk of heart attacks will improve ACS patient's symptom recognition and response.
- Trial name
- NCT04995900
- Testing
- Community education
- Where
- Australia
- Volunteers
- 2,240 people
- Sponsor
- Monash University
STEMI
Randomized Placebo-controlled Trial of Inhaled iNO in Acute ST-segment Elevation MI Treated by Primary Angioplasty
Reperfusion of ischemic myocardium, termed ischemia/reperfusion during the treatment of MI may result in paradoxical myocardial injury compromising myocardial salvage and left ventricular functional recovery.
- Trial name
- ENAMOR (NCT00854711)
- Testing
- inhaled nitric oxide
- Where
- Israel
- Volunteers
- 7 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
ST-Elevation Myocardial Infarction
Endothelin Receptor Blockade in Acute ST-elevation Myocardial Infarction
Background and Objective: Acute coronary syndrome is characterized by compromised blood flow at the epicardial and microvascular levels.
- Trial name
- NCT00502528
- Testing
- BQ-123
- Where
- Austria
- Volunteers
- 57 people
- Sponsor
- Medical University of Vienna
Coronary Disease, Myocardial Infarction
Fluvastatin in the Therapy of Acute Coronary Syndrome
This study is to evaluate the safety and efficacy of fluvastatin versus placebo, dosed shortly after or immediately when the coronary event occurs.
- Trial name
- NCT00171275
- Testing
- Fluvastatin
- Where
- Czechia
- Volunteers
- 1,000 people
- Sponsor
- Novartis
Coronary Stenosis, Acute Coronary Syndrome
Systemic, Pancoronary and Local Coronary Vulnerability
The aim of the VIP study is to investigate the impact of vulnerability markers (inflammatory serum biomarkers for systemic vulnerability, coronary shear stress and vulnerability mapping for pancoronary vulnerability, and…
- Conditions
- Coronary Stenosis, Acute Coronary Syndrome, Acute Myocardial Infarction, Atheromatous Plaques
- Trial name
- VIP (NCT03606330)
- Testing
- Cardiac imaging tests, Venous blood sample collection
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- Cardio Med Medical Center
Acute Myocardial Infarction (AMI)
Dexrazoxane to Protect Against Hemorrhagic STEMI
This Phase Ila trial evaluates whether the intravenous administration of Dexrazoxane can reduce permanent heart muscle damage in patients undergoing standard stent procedures (PCI) for a severe heart attack (STEMI).
- Trial name
- SHIELD-MI (NCT07502521)
- Testing
- Dexrazoxane, Normal Saline
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Rohan Dharmakumar
ST-elevation Myocardial Infarction
Comparison of Biomatrix Versus Gazelle in ST-Elevation Myocardial Infarction (STEMI)
Stent study: Treatment of patients with acute myocardial infarction with drug eluting stents (DES) is effective but there remain concerns regarding the long-term safety and adverse effects on the adjacent arterial wall.
- Trial name
- COMFORTABLE (NCT00962416)
- Testing
- Biolimus eluted from an erodable stent coating (Biomatrix), bare-metal stent (Gazelle)
- Where
- 5 sites in Switzerland
- Volunteers
- 1,161 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Risk Stratification
Predicting Ventricular Tachyarrhythmias Following Acute ST Elevation Myocardial Infarction
Predict-VT is an investigator-initiated, prospective, observational clinical trial. Four hundred patients with ST elevation acute myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI) will be…
- Trial name
- PREDICT-VT (NCT03263949)
- Testing
- Diagnostic
- Where
- Serbia
- Volunteers
- 400 people
- Sponsor
- Clinical Centre of Serbia
Acute Anterior Myocardial Infarction
Rapid Intravascular Cooling in Myocardial Infarction as Adjunctive to Percutaneous Coronary Intervention
Rapid MI-ICE-Pilot is designed to demonstrate the safety and efficacy of the Celsius Control™ System (CCS) endovascular catheter to reduce the infarct size resulting from acute anterior myocardial infarction when used in…
- Trial name
- NCT00417638
- Testing
- Endovascular cooling by the Celsius Control System, Standard of care
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- ZOLL Circulation, Inc., USA