Clinical trials: Acute Myocardial Infarction, completed
Coronary Artery Stent Thrombosis
Platelet Reactivity in Stent Thrombosis Patients
Recent studies have demonstrated a marked interindividual variability of clopidogrel's capacity to inhibit platelet aggregation with a substantial proportion (11-34%) of the patients considered non-responders to clopidogrel…
- Trial name
- MAPCAT (NCT01012544)
- Testing
- Clopidogrel
- Where
- Netherlands
- Volunteers
- 187 people
- Sponsor
- St. Antonius Hospital
Myocardial Infarction
Routine Angioplasty and Stenting After Fibrinolysis for Acute Myocardial Infarction
Background: In Canada, most patients with acute myocardial infarction (AMI) present to hospitals without cardiac catheterization facilities. Thrombolytic therapy remains the standard-of-care in these centres.
- Trial name
- NCT00164190
- Testing
- Routine Early Percutaneous Coronary Intervention after Thrombolysis
- Where
- Canada
- Volunteers
- 1,200 people
- Sponsor
- Canadian Heart Research Centre
Cardiac Arrest, Renal Failure
The Vital Signs to Identify, Target, and Assess Level (VITAL) Care Study III
To evaluate the effect of automated recording on frequency of recorded scores, number of automated notifications and serious events.
- Conditions
- Cardiac Arrest, Renal Failure, Respiration Failure, Myocardial Infarction
- Trial name
- NCT02973243
- Testing
- Automatic RR Measurement
- Where
- United Kingdom
- Volunteers
- 446 people
- Sponsor
- Philips Healthcare
Acute Myocardial Infarction
Morphine In Acute Myocardial Infarction
The purpose of this study is to determine whether intracoronary injection of morphine chlorhydrate is effective to limit ischemia-reperfusion lesion during percutaneous coronary angioplasty in patients with acute myocardial…
- Trial name
- MIAMI (NCT01186445)
- Testing
- morphine chlorhydrate, saline solution
- Where
- 2 sites in France
- Volunteers
- 94 people
- Sponsor
- French Cardiology Society
Acute Coronary Syndrome, Myocardial Infarction, Acute
Heart Matters: The Effectiveness of Heart Health Education in Regions at Highest-risk.
The aim of the study is to evaluate whether providing a targeted heart health education campaign to regions at high risk of heart attacks will improve ACS patient's symptom recognition and response.
- Trial name
- NCT04995900
- Testing
- Community education
- Where
- Australia
- Volunteers
- 2,240 people
- Sponsor
- Monash University
Non-ST Segment Elevation Myocardial Infarction, ST Segment Elevation Myocardial Infarction
Comparison of Clopidogrel and Ticagrelor on Microvascular Dysfunction in ST-Segment Elevation Myocardial Infarction
Ticagrelor is a non-thienophyridine, direct P2Y12 blocker that is more potent than clopidogrel and is associated with less interindividual variability.
- Trial name
- NCT02026219
- Testing
- Clopidogrel, Ticagrelor
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Inha University Hospital
Myocardial Infarction
Bone Marrow Stem Cell Mobilisation Therapy for Acute Myocardial Infarction (AMI)(REVIVAL-2)
The purpose of this study is to determine whether stem cell mobilization by granulocyte colony-stimulating factor (G-CSF) therapy in patients with acute myocardial infarction after successful mechanical reperfusion reduces…
- Trial name
- NCT00126100
- Testing
- G-CSF Granulocyte-Colony Stimulating Factor
- Where
- 2 sites in Germany
- Volunteers
- 114 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Аcute Coronary Syndrome
Registry of Acute Coronary Syndrome in the Regional Cardiovascular Center
The study is a prospective registry of patients consequently admitted to the regional cardiovascular center with a diagnosis of acute coronary syndrome, in order to study the behavior of patients from the first minutes of the…
- Trial name
- STOCS (NCT06845384)
- Where
- Russia
- Volunteers
- 555 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Acute Myocardial Infarction
Interleukin-1 (IL-1) Blockade in Acute Myocardial Infarction (VCU-ART3)
VCU-ART3 is a double-blind randomized clinical trial of anakinra high dose vs anakinra standard dose vs placebo in patients with ST-segment elevation myocardial infarction (STEMI) measuring the effects on the acute rise and fall…
- Trial name
- VCU-ART3 (NCT01950299)
- Testing
- Anakinra 100 mg
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- Virginia Commonwealth University
Acute Coronary Syndrome, Myocardial Infarction
Safety and Efficacy of LMWH Versus Rivaroxaban in Chinese Patients Hospitalized With Acute Coronary Syndrome
H-REPLACE trial is a prospective, randomized, open-label, active-controlled, multicenter study in participants with ACS (STEMI or NSTEMI, unstable angina).
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Myocardial Ischemia, Unstable Angina
- Trial name
- H-REPLACE (NCT03363035)
- Testing
- Rivaroxaban 2.5 mg, Rivaroxaban 5 mg, Enoxaparin
- Where
- 24 sites in China
- Volunteers
- 2,055 people
- Sponsor
- Second Xiangya Hospital of Central South University
Acute Myocardial Infarction
The Norwegian Vitamin Trial (NORVIT)
The purpose of this study is to examine whether the lowering of blood homocysteine levels by treatment with B vitamins can prevent cardiovascular disease
- Trial name
- NCT00266487
- Testing
- Folic acid, Vitamin B12, Vitamin B6
- Where
- Norway
- Volunteers
- 3,750 people
- Sponsor
- University of Tromso
Acute Myocardial Infarction
Place of Copeptin-troponin Assay in the Elimination Diagnosis of Non-ST+ ACS
The aim of this study is to demonstrate that a combined troponin and copeptin assay can exclude non-ST+ ACS in patients with chest pain less than 6 hours old.
- Trial name
- CopSCA (NCT05902117)
- Testing
- Troponin and Copeptin assay
- Where
- 2 sites in France
- Volunteers
- 270 people
- Sponsor
- Hôpital NOVO
Acute Coronary Syndrome, Myocardial Infarction
Point of Care (POC) Biomarkers of Ischemia
Acute coronary syndrome is defined as myocardial infarction or ischemia as evidenced by significant coronary artery disease on cardiac catheterization/revascularization or reversible defect seen on stress test.
- Trial name
- NCT02039882
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Acute Anterior Wall Myocardial Infarction
Autologous Stem Cell Transplantation in Acute Myocardial Infarction
Objectives Intracoronary transplantation of different cell populations have been used in acute myocardial infarction (AMI) with promising results.
- Trial name
- NCT00199823
- Testing
- Intracoronary aotologous stem cell transplantation
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Myocardial Infarction, Death
Prognostic Impact of Organ Damage in STEMI Patients
Besides contrast-induced acute kidney injury (CI-AKI), adscititious vital organ damage such as hypoxic liver injury (HLI) may affect the survival in patients with ST-elevation myocardial infarction (STEMI).
- Conditions
- Myocardial Infarction, Death, Acute Kidney Injury, Hepatic Insufficiency
- Trial name
- NCT02800421
- Volunteers
- 668 people
- Sponsor
- Inha University Hospital
Cardiopulmonary Arrest, Epinephrine Causing Adverse Effects in Therapeutic Use
Impact of Intracoronary Versus Intravenous Epinephrine Administration During Cardiac Arrest .
In hospital cardiac arrest (IHCA) is a major challenge imposed on almost all health care systems worldwide. Despite significant progress in cardiopulmonary resuscitation in the past few years, outcomes remain relatively poor with…
- Trial name
- (iCPR) (NCT05253937)
- Testing
- Epinephrin
- Where
- Lithuania
- Volunteers
- 160 people
- Sponsor
- Lithuanian University of Health Sciences
Acute Heart Failure
FranceLEVO - Zimino Registry (FZR)
The French National Authority for Health (Haute Autorité de santé) requested a registry study to obtain post-market surveillance data to describe baseline clinical profiles, management and outcome of patients treated with…
- Trial name
- FZR (NCT04252404)
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Arcothova
Hyperglycemia, Cardiovascular Diseases
REsearching Coronary REduction by Appropriately Targeting Euglycemia (RECREATE Pilot Study)
Insulin will safely reduce glucose levels in patients with acute ST-elevation myocardial infarction and admission hyperglycemia.
- Conditions
- Hyperglycemia, Cardiovascular Diseases, Myocardial Infarction
- Trial name
- RECREATE Pilot (NCT00640991)
- Testing
- glulisine insulin, glargine insulin
- Where
- 13 sites in Argentina, Canada and 1 more
- Volunteers
- 500 people
- Sponsor
- Population Health Research Institute
Acute Myocardial Infarction
Drug Eluting Stent (DES) in Primary Angioplasty
Stent implantation is the best treatment in patients with acute myocardial infarction (STEMI) referred for primary angioplasty (pPCI).
- Trial name
- PASEO (NCT00759850)
- Testing
- Drug Eluting Stent (DES)
- Where
- Italy
- Volunteers
- 270 people
- Sponsor
- San Giuseppe Moscati Hospital
Acute Myocardial Infarction
Bone Marrow Cells in Myocardial Infarction
This study is aimed to assess the effect of bone marrow cells on arrhythmia risk variables in patients with a acute myocardial infarction.
- Trial name
- NCT00363324
- Testing
- intracoronary injection of bone marrow cells
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- University of Oulu