Clinical trials: Acute Myocarditis
Myocarditis Acute, Ventricular Arrythmia
Ventricular Arrhythmia After Myocarditis in Sportsman
The study aims to assess the prevalence of ventricular rhythmic disorder after an acute myocarditis in sportsmen. 50 patients with acute myocarditis, confirmed by MRI, will be assessed by ECG Holter and Treadmill stress test…
- Trial name
- ARYMYS (NCT03842592)
- Testing
- Treadmill Stress test
- Where
- 4 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
COVID-19 Infection
Cardiac and Thoracic Imaging in Pediatric Patients With Evidence of Systemic Inflammation COVID19 Linked
To perform comprehensive cardiac and thoracic non invasive imaging assessment by MRI and/or CT scan including cardiac functional evaluation and myocardial tissue characterization of COVID_19 related disease in pediatric patients…
- Trial name
- CARDOVID (NCT04455347)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Imagine Institute
Myocarditis
International Myocarditis Registry
Myocarditis is an inflammatory heart disease primarily of viral origin that can lead to heart failure and death. Despite an unfavorable long-term outcome and mortality rate as high as 50%, classification, diagnosis, and treatment…
- Trial name
- mmr (NCT01307735)
- Where
- Canada
- Volunteers
- 78 people
- Sponsor
- Libin Cardiovascular Institute of Alberta
Myocarditis
Acute Eosinophilic Myocarditis International Registry
Retrospective collection of clinical, histological, imaging data regarding patients with acute histologically-proven eosinophilic myocarditis.
- Trial name
- NCT06447935
- Testing
- No intervention
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Niguarda Hospital
Myocarditis Acute, Ventricular Arrythmia
Evaluation of Long-term Incidence of Ventricular Arrhythmias in Patients With Acute Myocarditis
Myocarditis is an inflammatory disease of the heart muscle which is mostly caused by viruses, bacteria, parasites, toxic substances/drugs or by primary autoimmune mechanisms.
- Trial name
- AIM-ICD (NCT04264455)
- Testing
- Biomonitor, Life Vest, Implantable Cardioverter-Defibrillator (ICD)
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- Wuerzburg University Hospital
Myocarditis Acute, Myocardial Inflammation
CMR Evaluation of Myocardial Inflammation Persistence After Acute Myocarditis: Prognostic Relevance
Patients with acute myocarditis (AM) usually experience spontaneous healing, but a considerable percentage of them evolve towards chronic long-term cardiac impairment.
- Trial name
- MIAMI (NCT03525639)
- Testing
- Cardiac Magnetic Resonance
- Where
- 3 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Antonio Esposito
Cardiac Imaging Techniques, Cardiac Imaging
Role of Spectral CT in the Diagnosis of Myocarditis/MINOCA in Patients Undergoing cardioCT Investigations for Acute Chest Pain
It is a spontaneous, observational cross-sectional and single-center imaging (CT and MRI) study, coupled with clinical-laboratory data.
- Conditions
- Cardiac Imaging Techniques, Cardiac Imaging, Myocardial Disease, Myocarditis Acute
- Trial name
- NCT06804278
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Myocarditis
Acute Myocarditis Registry With Prognostic, Histologic, Immunologic, Biological, Imaging and Clinical Assessment
The AMPHIBIA study is an observational ambispective and prospective cohort that aim to describe the histologic, immunologic, biological, imaging, genetic and clinical characteristics of the patients hospitalized for an acute…
- Trial name
- AMPHIBIA (NCT04844151)
- Where
- France
- Volunteers
- 1,400 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocarditis Acute
French Registry of CMR Late Gadolinium Enhancement in Myocarditis
Acute myocarditis is a major cause of death in young adults and carries substantial morbidity, including a significant risk of progression to dilated cardiomyopathy.
- Trial name
- MYOCARDITI-LGE (NCT07394543)
- Volunteers
- 5,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocarditis Acute
MYTHS - MYocarditis THerapy With Steroids
This is a phase III, multi-center international, single blind randomized controlled trial to test the efficacy of pulsed intravenous (IV) methylprednisolone versus standard therapy on top of maximal support in patients with Acute…
- Trial name
- MYTHS (NCT05150704)
- Testing
- Methylprednisolone, saline solution
- Where
- 49 sites in United States, Austria and 7 more
- Volunteers
- 288 people
- Sponsor
- Niguarda Hospital
Myocarditis
Clinical, Morphological and Functional Aspects in Myocarditis.
Cardiac magnetic resonance (CMR) is accurate to identify acute myocardial damage (edema, hyperemia, and/or fibrosis) due to acute myocarditis (AM).
- Trial name
- NCT04217876
- Testing
- post-processing analysis of cardiac imaging (strain echocardiography)
- Where
- 4 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Messina
Coronary Artery Disease, Arrhythmias, Cardiac
Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics
The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear.
- Conditions
- Coronary Artery Disease, Arrhythmias, Cardiac, Heart Valve Diseases, Aortic Dissection
- Trial name
- PROSPECT (NCT06001073)
- Testing
- Observational; No Interventions were given.
- Where
- China
- Volunteers
- 25,000 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Viral Myocarditis, Cardio-Renal Syndrome
Risk Factors for Predictors of In-hospital Death in Acute Fulminant Myocarditis
The investigators performed a retrospective, single-center observational study, and the participants with acute fulminant myocarditis were included.Then, the investigator analyzed the risk factors of in-hospital death in these…
- Conditions
- Viral Myocarditis, Cardio-Renal Syndrome, Risk Factor, Cardiovascular
- Trial name
- NCT03219996
- Testing
- prognosis
- Volunteers
- 76 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Myocarditis
Role of Matrix Metalloproteinases (MMPs) and Tissue Inhibitors of Metalloproteinases (TIMPs) in Children With Myocarditis
Children can have or develop certain problems with their heart function, specifically with the heart muscle or myocardium. This problem can be caused by many things specifically by infection resulting in myocarditis (inflammation…
- Trial name
- NCT00693134
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Myocarditis Acute, Cancer
Abatacept in Immune Checkpoint Inhibitor Myocarditis
The primary aim is to test whether abatacept, as compared to placebo, is associated with a reduction in major adverse cardiac events (MACE) among participants hospitalized with myocarditis secondary to an immune checkpoint…
- Trial name
- ATRIUM (NCT05335928)
- Testing
- Abatacept plus
- Where
- 31 sites in United States, Canada
- Volunteers
- 390 people
- Sponsor
- Massachusetts General Hospital
COVID-19
Descriptive and Retrospective Analysis of Acute Myocarditis Associated With Pandemic COVID-19 in Children
The study objectives are to descript clinical, biological and echocardiographic features of an acute myocarditis in children in the context of COVID-19 and to identify the underlying mechanism : direct viral damage and/or…
- Trial name
- HEART-COVID (NCT04420468)
- Where
- 4 sites in France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocarditis Acute
MCE Molecular Imaging for Myocarditis
Inflammation of the heart (myocarditis) is a serious condition that can cause heart failure, abnormal heart rhythms, cardiac arrest, and death. Rapid diagnosis of this condition is key to reversing it.
- Trial name
- NCT07538544
- Testing
- Myocardial contrast echocardiography molecular imaging for inflammation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Virginia
Myocarditis Acute
Non-Steroidal Anti-Inflammatory Drugs in Acute Myocarditis
Prospective, randomized, multicenter, open-label clinical trial to evaluate the safety and efficacy of a 3-week ibuprofen tapering regimen compared to conventional analgesic treatment (acetaminophen) in patients with acute…
- Trial name
- INFLAMA (NCT06686862)
- Testing
- ibuprofen
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
Myocarditis, Cardiomyopathy, Dilated
French National Observatory Tracking Viral Myocarditis: Mortality, Cardiovascular Events, Sequels on (Magnetic Resonance Imaging) MRI
Acute myocarditis is a serious illness affecting a young population with a very variable course (of full recovery at the onset of dilated cardiomyopathy (DCM), or even sudden death).
- Conditions
- Myocarditis, Cardiomyopathy, Dilated, Magnetic Resonance Imaging
- Trial name
- MYOCARDITIRM (NCT02717143)
- Where
- France
- Volunteers
- 821 people
- Sponsor
- French Cardiology Society
Myocarditis
Prognostic Role of High Sensitivity Troponin During Follow up in the Evolution of Acute Myocarditis
The goal of this observational study is to observe if ultra-sensitive troponins (us) measurement between 3 and 6 months after the acute event will be sensitive enough to dispense with all other examinations, particularly cardiac…
- Trial name
- PROGNOSTIC (NCT05949450)
- Where
- France
- Volunteers
- 244 people
- Sponsor
- University Hospital, Grenoble