Clinical trials: Acute Normovolemic Hemodilution
Acute Normovolemic Hemodilution, Bone Tumor
The Effect of Acute Normovolemic Hemodilution in Bone Tumor Surgery
The prevention of intraoperative allogenetic blood transfusion has the potential to reduce complications, hospital stays, and long-term prognosis in patients undergoing bone cancer surgery.
- Conditions
- Acute Normovolemic Hemodilution, Bone Tumor, Goal-Directed Fluid Therapy, Transfusion
- Trial name
- NCT06459141
- Testing
- acute normovolemic hemodilution
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Normovolemic Hemodilution, Off-Pump Coronary Artery Bypass Surgery
Acute Normovolemic Hemodilution in Off-pump CABG
To study the effects of Acute normovolemic hemodilution on central and peripheral perfusion in patients Undergoing off-pump coronary artery bypass grafting surgery
- Trial name
- NCT04042883
- Testing
- Acute normovolemic hemodilution
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Postoperative Hemorrhage, Postoperative Anemia
Autologous Whole Blood Management for Transfusion Reduction in Adult Cardiac Surgery Patients
The goal of this pilot trial is to test a protocol for a planned Canada-wide clinical trial looking at whether or not the use of a patients own blood works as good as the current standard of care using donated blood products to…
- Conditions
- Postoperative Hemorrhage, Postoperative Anemia, Postoperative Blood Loss
- Trial name
- NCT05889494
- Testing
- Autologous Whole Blood Management, Standard Care involving allogenic and/or derivative transfusion.
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Acute Normovolemic Hemodilution
Acute Normovolemic Hemodilution in Bone Cancer Surgery
Malignant bone tumors often lead to skeletal complications, known as skeletal related events (SRE). These complications mainly include pathological fractures, severe pain, and spinal cord compression.
- Trial name
- NCT07669155
- Testing
- Acute Normovolemic Hemodilution
- Where
- 8 sites in China
- Volunteers
- 420 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ovarian Neoplasm Epithelial
The Effects of Hemodilution Methods in Patients Undergoing Primary Debulking Gynaecological Surgery
Primary cytoreductive surgery for ovarian cancer is an ideal setting to evaluate endothelial function under ANH and AHH, as the procedure is associated with moderately high blood loss.
- Trial name
- NCT06103214
- Testing
- acute normovolemic hemodilution (ANH), acute hypervolemic hemodilution (AHH)
- Volunteers
- 144 people
- Sponsor
- Zhejiang Cancer Hospital
Epithelial Ovarian Cancer, Fallopian Tube Cancer
Acute Normovolemic Hemodilution in Patients Undergoing Cytoreductive Surgery for Advanced Ovarian Cancer
The purpose of this study is to help us learn how to lower the risk of a blood transfusion during surgery to remove ovarian cancer.
- Conditions
- Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma
- Trial name
- NCT01442051
- Testing
- Acute Normovolemic Hemodilution
- Where
- 4 sites in United States
- Volunteers
- 52 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Acute Normovolemic Hemodilution
Clinical Study on the Effectiveness and Safety of Succinylated Gelatin Electrolyte Sodium Acetate Injection
The succinylated gelatin electrolyte sodium acetate injection (specification: 500 mL: 20 g) developed and produced by Nanjing Chia-tai Tianqing Pharmaceutical.
- Trial name
- NCT06977750
- Testing
- succinylated gelatin electrolyte sodium acetate injection 1, succinylated gelatin electrolyte sodium acetate injection
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Nanjing Chia-tai Tianqing Pharmaceutical
Cardiac Surgery, Acute Normovolemic Hemodilution
Application of Large Volume Acute Normovolemic Hemodilution in Cardiac Surgery
The application of acute Normovolemic Hemodilution in cardiac surgery can effectively reduce perioperative blood transfusion, reduce postoperative complications and mortality, and is a low-cost, operable and effective blood…
- Trial name
- NCT04369443
- Testing
- Large volume Acute Normovolemic Hemodilution
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Baseline, Hemodilution
Performance of Non-Invasive Monitors During ANH
The aim of this study is to assess the responsiveness of the standard minimally invasive hemodynamic monitors used in the operating room to known changes in the intravascular volume status that occur during blood removal and…
- Trial name
- NCT02179827
- Where
- United States
- Sponsor
- University of California, Davis
Cardiac Disease
Comparison of ACT Between Hemochron Jr and ACT Plus
This study aimed to compare 2 activated clotting time analysers (Hemochron Jr vs. ACT Plus).
- Trial name
- NCT02484157
- Testing
- Hemochron, ACT Plus
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- Hallym University Medical Center
Coagulation Disorder, Bleeding
Coagulation Test Changes Associated With Acute Normovolemic Hemodilution in Cardiac Surgery
The researchers are trying to reduce the need for blood transfusions in subjects having surgery that will involve the use of cardiopulmonary bypass.
- Trial name
- NCT03647644
- Testing
- Coagulation Laboratory Testing
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
Mitral Regurgitation, Mitral Stenosis
Mild ANH on Pre-bypass Coagulation Function During Cardiac Surgery
The impact of acute normovolemic hemodilution (ANH) using hydroxyethyl starch before initiating cardiopulmonary bypass (CPB) on whole blood viscoelastic profile after CPB has not been well established.
- Conditions
- Mitral Regurgitation, Mitral Stenosis, Tricuspid Regurgitation
- Trial name
- NCT06664320
- Testing
- Acute normovolemic hemodilution (ANH), hydroxyethyl starch (HES 130/0.6)
- Where
- 2 sites in South Korea
- Volunteers
- 70 people
- Sponsor
- Konkuk University Medical Center
Cardiac Defect
Safety and Efficacy of Acute Normovolemic Hemodilution in Pediatric Cardiac Surgery Patients
The investigators primary objective is to determine if acute normovolemic hemodilution (ANH) for pediatric cardiac surgical patients decreases the volume of blood products transfused during surgery and the immediate…
- Trial name
- NCT02751645
- Testing
- Acute Normovolemic hemodilution
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Oregon Health and Science University
Acute Hypovolemia
Esophageal Echo Assessment of LV Function During Acute Normovolemic Hemodilution Using Crystalloid or Hypertonic Saline
The purpose of this study is to examine how the heart functions when a calculated amount of blood is removed and how two fluids, Lactated Ringer's (considered the standard replacement fluid) and Hypertonic Saline, re-expand the…
- Trial name
- NCT00683007
- Testing
- Volume resuscitation (Crystalloid), Volume resuscitation (Hypertonic Saline Solution)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of California, Davis
Cardiac Surgical Procedures
The Impact of Storage Techniques on Platelets Number and Function After Acute Normovolemic Hemodilution (ANH)
Acute normovolemic hemodilution (ANH) is part of our current protocol to decrease post-operative bleeding and homologous blood transfusions post cardiopulmonary bypass.
- Trial name
- NCT02060838
- Testing
- Acute normovolemic hemodilution (ANH)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Aymen N Naguib
Liver Cancer
Controlled Trial Comparing Nomogram-based Versus Standard Allocation of Acute Normovolemic Hemodilution (ANH) During Hepatic Resection
The purpose of this study is to learn the best method of assigning patients to receive "acute normovolemic hemodilution" during liver surgery.
- Trial name
- NCT00902343
- Testing
- nomogram-based selection for acute normovolemic hemodilution, standard selection for ANH based on a planned resection of 3 or more segments
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Ovarian Cancer, Fallopian Tube Carcinoma
Study of Acute Normovolemic Hemodilution (ANH) in People With Ovarian Cancer Who Are Having Cytoreductive Surgery
Participants will be scheduled for primary cytoreductive surgery as part of their standard care. Before surgery, participants will be assigned by chance to a study group.
- Conditions
- Ovarian Cancer, Fallopian Tube Carcinoma, Ovarian Carcinoma, Peritoneal Carcinoma
- Trial name
- NCT06290193
- Testing
- Acute Normovolemic Hemodilution/ANH
- Where
- 7 sites in United States
- Volunteers
- 86 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Surgery
Effect of Acute Normovolemic Haemodilution on Allogenic Transfusion Needs In Laparotomy
This study is aimed to determine if acute normovolemic hemodilution (ANH), an established blood conservation technique, reduces the requirement for allogeneic blood transfusion in operations with prediction of surgical bleeding…
- Trial name
- ANH (NCT02290964)
- Testing
- ANH
- Where
- Indonesia
- Volunteers
- 34 people
- Sponsor
- Universitas Padjadjaran
Surgery--Complications, Blood Transfusion Complication
Acute Normovolemic Hemodilution (ANH) in Patients Undergoing Cardiac Surgery
The purpose of this small randomized pilot study is to evaluate adherence to strict transfusion protocols in both the control and ANH group examining compliant and noncompliant transfusion rates and reasons for violation of the…
- Trial name
- NCT04127825
- Testing
- Acute Normovolemic Hemodilution (ANH)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Minnesota
Ischemic Heart Disease, Coronary Artery Disease
Impact of Acute Normovolemic Hemodilution on Blood Viscosity
Acute normovolemic hemodilution (ANH) has long been employed for reducing allogenic blood transfusion for cardiac surgery, and hydroxyethyl starch has been used as an intravenous replacement fluid during ANH procedure.
- Trial name
- NCT03366753
- Testing
- acute normovolemic hemodilution, In-vitro hemodilution
- Where
- South Korea
- Volunteers
- 21 people
- Sponsor
- Konkuk University Medical Center