Clinical trials: Acute Pain, completed
Acute Coronary Syndrome, Chest Pain
Efficacy Evaluation of Observation Unit Cardiac Magnetic Resonance Imaging (MRI) in Patients With Intermediate Risk Acute Chest Pain
The purpose of this study is to investigate the best way to evaluate patients with chest pain in the emergency department. It compares types of cardiac tests performed while receiving treatment in an observation unit.
- Trial name
- NCT00869245
- Testing
- OU - Cardiac MRI, OU - Conventional Care Testing
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Wake Forest University Health Sciences
Pain, Postoperative
Thoracic Paravertebral Blockade in Video Assisted Thoracoscopic Surgery (VATS)
Video-assisted thoracoscopic surgeries (VATS) include severe postoperative acute pain which is also a predictor of chronic pain.
- Trial name
- VATS (NCT02302586)
- Testing
- Thoracic paravertebral block (TPVB), Patient Controlled Analgesia (IV PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Pain, Back, Pain, Acute
Relieving Pain and Improving Sleep: Evaluating Topical Pain Relief and Sleep Patches
This minimal risk, randomized, double-blind, placebo controlled Institutional Review Board (IRB)-approved study with functional measurements, will evaluate pain relief and sleep improvement after use of a drug- free, non-invasive…
- Conditions
- Pain, Back, Pain, Acute, Sleep Disorder, Sleep Disorders, Circadian Rhythm
- Trial name
- RESTORE (NCT06505005)
- Testing
- Drug- free, non-invasive patch (FREEDOM or REM Patch) with haptic vibrotactile trigger technology (VTT) Other Names:
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- SuperPatch Limited LLC
Hydromorphone Use, Acute Postoperative Pain
Methadone and Hydromorphone For Spinal Surgery
Patients undergoing major spinal surgery continue to experience moderate-to-severe pain during the first 2-3 days following the operative procedure.
- Conditions
- Hydromorphone Use, Acute Postoperative Pain, Patient Satisfaction, Chronic Persistent Surgical Pain
- Trial name
- NCT02107339
- Testing
- Methadone, Hydromorphone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Thoracic Surgery, Uniportal Video Assisted Thoracic Surgery (U-VATS)
Erector Spinae Plane Block in Uniportal VATS
The main aim of this study is to compare the effectiveness of three alternative techniques (continuous Erectus Spinae Plane Block : c-ESPB; continuous Serratus Anterior Plane Block : c-SAPB; and Intercostal Nerve Block: ICNB) in…
- Conditions
- Thoracic Surgery, Uniportal Video Assisted Thoracic Surgery (U-VATS), Lung Resections, Post-Operative Pain, Chronic
- Trial name
- ESPB-UVATS (NCT04892901)
- Testing
- c-ESPB, c-SAPB, ICNB
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Unilateral Cataract Extraction, Congenital Cataract
A Randomized Study in Children Ages Birth Through Three Years Undergoing Unilateral Cataract Extraction With or Without Lens Replacement
The purpose of this study is to evaluate the effect of OMS302 compared to phenylephrine when administered in irrigation solution during cataract extraction on intraoperative pupil diameter, acute postoperative pain, and safety in…
- Trial name
- ILR7 (NCT02132312)
- Testing
- OMS302, Phenylephrine HCl
- Where
- 11 sites in United States
- Volunteers
- 78 people
- Sponsor
- Omeros Corporation
Hip Fractures, Pain, Acute
Pericapsular Nerve Group Block for Hip Fractures
This will be a feasibility study to see if it feasible to perform the Pericapsular Nerve Group Block for hip fractures in the Emergency Department.
- Trial name
- NCT04882384
- Testing
- Pericapsular Nerve Group Block
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jacobi Medical Center
Analgesia, Acute Pain
Comparison of the Effects of TFPB and Anterior QLB on Postoperative Analgesia in Cesarean Section Surgery
This study evaluates the postoperative analgesic effects of transversalis fascia plane block and anterior quadratus lumborum block in patients having cesarean section under general anesthesia.
- Conditions
- Analgesia, Acute Pain, Chronic Pain
- Trial name
- NCT05408403
- Testing
- Regional anesthesia TFPB, Regional anesthesia QLB
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Ondokuz Mayıs University
Bunionectomy, Pain
A Trial to Evaluate CG5503 Efficacy and Safety in Acute Pain After Bunionectomy
The main objective of this trial is to demonstrate the efficacy and safety of multiple-dose application of oral application of CG5503 IR 75mg compared to placebo and to assess safety and tolerability of CG5503 IR 75mg in subjects…
- Conditions
- Bunionectomy, Pain, Postoperative Pain, Acute Pain
- Trial name
- NCT00609466
- Testing
- CG5503 IR, Morphine
- Where
- 6 sites in United States
- Volunteers
- 291 people
- Sponsor
- Grünenthal GmbH
Wounds and Injuries, Rib Fractures
Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients
This study will evaluate the effectiveness of ketamine infusions in the management of acute pain resulting from broken ribs suffered following a blunt trauma.
- Trial name
- NCT02432456
- Testing
- Ketamine, Intercostal Nerve Block, Acetaminophen
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Medical College of Wisconsin
Acute Pancreatitis
Electroacupuncture for Acute Pancreatitis
This study aims to prove the efficacy of electroacupuncture (EA) for pain relief in patients with acute pancreatitis compared with conventional treatment.
- Trial name
- NCT03173222
- Testing
- Electroacupuncture
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- DongGuk University
Acute Pain
ESKetamine Low-dose vs Ketamine Low-dose for Severe Acute Pain in Emergency Units, Comparison of PsychodyslEptic Effects
Almost 30% of painful patients in emergency departments (ED) describe their pain as severe (i.e. a Verbal Numerical Rating Score VNRS ≥ 6 on a scale ranging from 0 to 10).
- Trial name
- ESKAPE (NCT06853041)
- Testing
- Esketamine, Ketamine
- Where
- France
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Headache, Acute, Focal Neurologic Disease
Digital Ocular Fundus Photography in the Emergency Department: A New Application for Telemedicine?
The purpose of this study is to determine if non-dilated retinal photography in the emergency room improves the diagnosis of papilledema (optic nerve swelling) in patients with neurologic disease compared to direct ophthalmoscopy.
- Conditions
- Headache, Acute, Focal Neurologic Disease, Severely Elevated Blood Pressure, Acute Visual Loss
- Trial name
- NCT00873613
- Testing
- Use of Non-dilated retinal photography
- Where
- United States
- Volunteers
- 705 people
- Sponsor
- Emory University
Anxiety, Postoperative Pain
Developing a Virtual Reality (VR)-Based Prototype for Perioperative Care - a Proof of Concept Study
Preoperative anxiety and acute post-operative pain are common and have been associated with the development of chronic post-surgical pain and longer hospitalisation.
- Conditions
- Anxiety, Postoperative Pain, Pain, Acute
- Trial name
- NCT05564013
- Testing
- Virtual reality
- Where
- 2 sites in Singapore
- Volunteers
- 160 people
- Sponsor
- Changi General Hospital
Acute Pain
Sub-dissociative Dose Ketamine Dosing Study
Goal is to determine if in adults presenting to the Emergency Department (ED) with moderate to severe acute pain, Ketamine administered at 0.15 mg/kg will provide similar pain relief to Ketamine administered at 0.3 mg/kg, with…
- Trial name
- NCT03714620
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Loyola University
Acute Pain, Postoperative Pain Control
An Efficacy and Safety Study of LTG-001 Following Abdominoplasty
The goal of this clinical trial is to learn if LTG-001 works to treat post-operative / acute pain after an abdominoplasty procedure. It will also learn more information on the safety of LTG-001.
- Trial name
- NCT07102459
- Testing
- Experimental: LTG-001 High Dose, Experimental: LTG-001 Low Dose, Active Comparator: HB/APAP
- Where
- 5 sites in United States
- Volunteers
- 343 people
- Sponsor
- Latigo Biotherapeutics
Acute Postoperative Pain, Bunionectomy
Evaluate the Efficacy and Safety of ACP-044 for the Treatment of Acute Postoperative Pain Following Bunionectomy
To evaluate the efficacy of ACP-044 compared with placebo in the treatment of acute postoperative pain
- Trial name
- NCT04855240
- Testing
- ACP-044 Dose A, ACP-044 Dose B
- Where
- 4 sites in United States
- Volunteers
- 239 people
- Sponsor
- ACADIA Pharmaceuticals Inc.
Procedural Pain
Skin Blood Flow Changes Using Laser Doppler Imager for Assessment of Pain and Analgesia in Newborn Infants
The purpose of this study is to assess whether an instrument, the Laser Doppler Imager, is able to measure the effect of pain related changes in skin blood flow in newborn infants.
- Trial name
- NCT00694174
- Testing
- sucrose 24% oral solution, sterile water
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Children's Hospital of Michigan
Acute Myeloid Leukemia, Stem Cell Leukemia
Nalbuphine Versus Morphine for Mucositis Pain in Pediatric Cancer Patients
Evaluation of safety and efficacy of Nalbuphine versus Morphine patient controlled analgesia (PCA) for mucositis pain in pediatric cancer patients
- Trial name
- PCA (NCT03825887)
- Testing
- Nalbuphine, Morphine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Children's Cancer Hospital Egypt 57357
Post-COVID-19 Syndrome, Back Pain
Kinesiotaping Versus Physiotherapy for Post-Covid-19 Back Pain
Objective: This study aims to compare and evaluate the effectiveness of kinesiotaping and traditional physiotherapy methods, which are frequently used in the treatment of musculoskeletal diseases, on mid-back pain (MBP) developed…
- Conditions
- Post-COVID-19 Syndrome, Back Pain, Musculoskeletal Pain
- Trial name
- NCT07744451
- Testing
- Kinesiotaping, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Medipol University
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