Clinical trials: Acute Pain, completed
Angina, Unstable
Pilot Study on Shear-induced Platelet Aggregation in Acute Coronary Syndromes
The purpose of this study is to determine whether shear-induced platelet aggregation is able to discriminate first acute coronary syndrome (ACS) from recurrent ACS
- Trial name
- REACS (NCT00299143)
- Where
- France
- Volunteers
- 97 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Myocardial Ischemia
Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST Elevation Acute Coronary Syndromes
MERLIN-TIMI 36 is a multi-national, double-blind, randomized, placebo-controlled, parallel-group clinical trial designed to evaluate the efficacy and safety of ranolazine during acute and long-term treatment in approximately…
- Trial name
- NCT00099788
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 6,560 people
- Sponsor
- Gilead Sciences
Acute Lumbar Sciatica Secondary to Disc Herniation
High Versus Low Level of Lumbar Traction in Acute Lumbar Sciatica Due to Disc Herniation
The aim of this study is to compare two levels (high and low forces) of short term lumbar traction on pain and functional tests of the lower limbs in a specific population of patients presenting with acute lumbar sciatica…
- Trial name
- NCT02091791
- Testing
- Traction sessions
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Strasbourg, France
Low Back Pain
Ibuprofen With or Without Acetaminophen for Low Back Pain
This is a randomized clinical trial comparing two interventions for acute low back pain: 1. Ibuprofen + acetaminophen 2. Ibuprofen + placebo Participants will include patients who present to an emergency room for management of…
- Trial name
- NCT03554018
- Testing
- Acetaminophen, Ibuprofen 600 mg, Educational intervention
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Montefiore Medical Center
Bipolar Disorder, Mania
The Efficacy and Safety of AChE Inhibitor Donepezil As Adjunctive Treatment to Mood Stabilizers in Acute Mania
There is a high rate of partial response to standard thymoleptic medication. In this study the investigators want to evaluate the safety and efficacy of donepezil as adjunctive treatment to mood stabilizers in bipolar disorder…
- Trial name
- NCT01191918
- Testing
- Donepezil and Lithium
- Volunteers
- 40 people
- Sponsor
- Shanghai Mental Health Center
Acute Postoperative Pain
Erector Spina Plane (ESP) Block in Pediatric Patients
In this study, we aimed to evaluate the erector spina plane (ESP) block method that we used in our clinic with ultrasonography in pediatric cases between 1 month and 2 years of age who underwent laparotomy.
- Trial name
- NCT04875390
- Testing
- Erector spina plane block, local infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara City Hospital Bilkent
Long COVID
Exercise for Health in Patients With Post-acute Sequelae of COVID-19
Background: Many patients with COVID-19 present the so-called post-acute sequelae of COVID-19 such as fatigue, post-stress discomfort, dyspnea, headache, pain mental impairment, incapacity to perform daily physical tasks ant…
- Trial name
- EJerSA-COVID (NCT05848518)
- Testing
- Rehabilitation program
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Campus docent Sant Joan de Déu-Universitat de Barcelona
Acute Coronary Syndromes, Stable Angina Pectoris
Angio-Seal® vs. Exo-Seal® for Closure of Arterial Puncture Sites
Background: Vascular closure devices (VCD) were developed to reduce access site bleedings, to improve patients´ comfort, and to accelerate ambulation after percutaneous coronary interventions (PCI).
- Trial name
- NCT01669382
- Testing
- percutaneous coronary intervention
- Where
- 3 sites in Germany
- Volunteers
- 304 people
- Sponsor
- University Hospital Erlangen
Child Behavior, Pain, Acute
The Effect of Therapeutic Play on Pain, Fear, Anxiety and Physiological Parameters and Parents' Satisfaction
In this study, the effect of the therapeutic game applied before treatment on pain, fear, anxiety and physiological parameters and the satisfaction of the parents was investigated.
- Conditions
- Child Behavior, Pain, Acute, Anxiety and Fear
- Trial name
- NCT06415188
- Testing
- Video game with headset
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Selcuk University
Acute Pain
Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy Surgery
The purpose of this study is to determine the effectiveness and safety of single intravenous doses of the kappa opioid agonist CR845 in relieving pain in patients following laparoscopic-assisted hysterectomy surgery.
- Trial name
- NCT00877799
- Testing
- CR845
- Where
- 12 sites in United States
- Volunteers
- 114 people
- Sponsor
- Cara Therapeutics, Inc.
Traumatic Brain Injury, Headaches Posttraumatic
Adjunct VR Pain Management in Acute Brain Injury
Severe and refractory pain after acute injury is a known-risk factor for chronic opioid use disorder. In this study, the investigators will use Virtual Reality (VR) immersion as a non-pharmacological adjunct to treat pain…
- Conditions
- Traumatic Brain Injury, Headaches Posttraumatic, Trauma, Pain, Acute
- Trial name
- NCT04356963
- Testing
- Virtual Reality Session (VR Blu), Tablet-based Session (Tablet Blu), Use of Virtual Reality Head Mounted Display without Content (VR Blank)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Maryland, Baltimore
Acute Pain, Post Operative Pain
Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following Bunionectomy
MR-107A-02 is being studied to investigate its efficacy and safety for treatment of acute pain after bunionectomy.
- Conditions
- Acute Pain, Post Operative Pain, Pain
- Trial name
- NCT06215820
- Testing
- MR-107A-02, Tramadol, Bunionectomy
- Where
- 15 sites in United States
- Volunteers
- 410 people
- Sponsor
- Viatris Specialty LLC
Neck Pain, Acute Pain
The Effectiveness of Patient-tailored Treatment in Patients With (Sub)Acute Neck Pain
The purpose of the present study is to examine if a patient-tailored treatment program has a better effect on pain and disability than a non-patient tailored treatment or wait and see approach in patients with (sub)acute…
- Conditions
- Neck Pain, Acute Pain, Rehabilitation, Physical Therapy Modalities
- Trial name
- NCT04182035
- Testing
- patient-tailored therapy, Non-patient tailored therapy: generalized exercise program, Education
- Where
- Belgium
- Volunteers
- 61 people
- Sponsor
- University Ghent
Benign Gynecological Disease
Predicting Acute Postoperative Pain by the Preoperative Lower Back Pain
To investigate if the level of preoperative lower back pain has the effect on the acute postoperative pain after gynecological laparoscopy
- Trial name
- NCT04793191
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- The Catholic University of Korea
Pain, Postoperative, Chronic Postoperative Pain
Analgesia in Laparoscopic Cholecystectomy
The investigators hypothesis is that perioperative infusion of 0.75 ropivacaine in patients undergoing laparoscopic cholecystectomy may modify the intensity of postoperative pain or the analgesic consumption during the first 24…
- Trial name
- NCT01388946
- Testing
- Ropivacaine 0.75, Normal saline
- Where
- 2 sites in Greece
- Volunteers
- 110 people
- Sponsor
- University of Athens
Herpes Zoster, Postherpetic Neuralgia
Acupuncture in Herpes Zoster Neuralgia (ACUZoster)
Symptoms that herald herpes zoster include pruritus, dysesthesia and pain along the distribution of the involved dermatome. The most distressing symptom is typically pain and the most feared complication is postherpetic neuralgia…
- Conditions
- Herpes Zoster, Postherpetic Neuralgia, Pain
- Trial name
- ACUZoster (NCT00885586)
- Testing
- gabapentine, Acupuncture
- Where
- Germany
- Volunteers
- 68 people
- Sponsor
- Dominik Irnich
Low Back Pain, Mechanical
The Biomechanical Effects of Manual Therapy - A Feasibility Study
The aim of this study is to determine the feasibility of conducting a full-scale trial to explore if there is a change in intervertebral movement following a course of manual therapy in patients with acute non-specific low back…
- Trial name
- NCT04155970
- Testing
- Manual therapy, Evidence-informed home management booklet
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Bournemouth University
Cartilage Diseases
Sampling Biomarkers in Meniscus Injury to the Knee
The diagnosis of clinically-significant meniscal tears of the knee remains challenging, and it is unknown why only some injuries become painful.
- Trial name
- NCT00836966
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Scuderi, Gaetano J., M.D.
Pain, Postoperative, Pain Sensitivity, Postoperative
Effect of Mobilization on Acute Postoperative Pain and Nociceptive Function
Aim of the present study is twofold. First we want to evaluate the effect of mobilization on acute postoperative pain Second to test weather chances in pain sensitivity are occurring following surgery and mobilization after total…
- Trial name
- NCT01018277
- Testing
- Mobilization (walking)
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Hvidovre University Hospital
Pain, Acute, Anxiety
Virtual Reality for Pain and Anxiety Distraction Strategy on Office Hysteroscopy
Hysteroscopy is a minimally invasive endoscopic technique that allows direct visualization of the uterine cavity and constitutes the gold standard for the diagnosis and treatment of most intrauterine pathology, such as heavy…
- Trial name
- VRPAD (NCT04721587)
- Testing
- Virtual Reality
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
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