Clinical trials: Acute Pain, completed
Rib Fractures, Pain, Acute
A Retrospective Review of Rib Fracture Pain Management at a London Major Trauma Centre
Thoracic epidural analgesia (TEA) is widely considered to be the current gold standard treatment for rib fracture pain and is used in the Imperial invasive treatment pathway for rib fractures.
- Trial name
- NCT04863807
- Testing
- Regional Anaesthesia
- Where
- United Kingdom
- Volunteers
- 389 people
- Sponsor
- Imperial College Healthcare NHS Trust
Chest Pain
Low-Dose Coronary Computed Tomographic Angiography for Early Triage of Acute Chest Pain
This study is to see whether the low-dose coronary computed tomographic angiography (CCTA) protocol is as safe and efficacious as conventional-dose protocol in early triage of acute chest pain.
- Trial name
- NCT01770444
- Testing
- Low-dose Cardiac CT protocol, Conventional cardiac CT protocol
- Where
- 3 sites in South Korea
- Volunteers
- 681 people
- Sponsor
- Seoul National University Hospital
Acute Pain
The Implementation of a Post-operative Communication App to Improve Pain Control and Opioid Use
Digital communication tools are becoming ubiquitous in healthcare, though their impact on patient/provider communication, healthcare utilization, and outcomes remains poorly established.
- Trial name
- NCT06124079
- Testing
- OPY interactive messaging service, Standard care
- Where
- United States
- Volunteers
- 3,442 people
- Sponsor
- University of Minnesota
Catheter Site Pain, Pain, Acute
A Study to Evaluate the Efficacy and Safety of Zingo in Chinese Children
The purpose of the study is to evaluate the efficacy and safety of Zingo in treating pain associated with venipunture and peripheral venous cannulation.
- Conditions
- Catheter Site Pain, Pain, Acute, Anesthesia, Local
- Trial name
- NCT03653260
- Testing
- Lidocaine (Zingo)
- Where
- China
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Lee's Pharmaceutical Limited
Pain
From ACute To Chronic Postoperative Shoulder Pain in Patients for Elective Lobectomy
Shoulder pain is a well known problem after thoracical surgery. The pathogenesis of the pain is uncertain, but mainly a mix of referred pain and mechanical strain to the shoulder. It is believed to last a few days.
- Trial name
- FACTS2 (NCT01552746)
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital
Acute Coronary Syndrome
Usefulness of a 2-hour Delta Troponin-I During the ED Identification and Exclusion of Acute Myocardial Infarction
1. In chest pain patients with suspected acute coronary syndrome, a 2-hr delta Troponin-I as measured by the i-STAT immunoassay reliably identifies and excludes an acute myocardial infarction. 2.
- Trial name
- NCT02002546
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Chattanooga-Hamilton County Hospital Authority
Shoulder Impingement Syndrome, Chronic Pain
Sensorimotor Cortex Excitability in Shoulder Impingement Syndrome
Shoulder pain is a common musculoskeletal system complaint, accounting for 7-34% of patients in the clinic. The most common shoulder problem is subacromial impingement syndrome (SIS).
- Conditions
- Shoulder Impingement Syndrome, Chronic Pain, Transcranial Magnetic Stimulation, Electroencephalography
- Trial name
- NCT05627986
- Testing
- No intervention
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Acute Respiratory Infections
Pain and Stress Assessment in Children
There may be pain and / or stress with vibrocompression. There may be pain and / or stress with the aspiration of secretions.
- Trial name
- NCT01731834
- Testing
- Vibrocompression and aspiration of secretions
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of Uberlandia
Pain, Acute, Anxiety
The Effects of Finger Puppet, Abeslang Puzzle, and Pinwheel on Pain and Anxiety During Blood Sampling Procedures
Blood sampling is an invasive, diagnostic, and therapeutic procedure for children. The inability of preschool children to differentiate between reality and imagination and their belief in the power of their thoughts make it…
- Conditions
- Pain, Acute, Anxiety, Child, Only
- Trial name
- NCT05904483
- Testing
- PFA
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Bartın Unıversity
Acute Coronary Syndrome (ACS), High On-treatment Platelet Reactivity (HTPR)
The Effect of IV Cangrelor and Oral Ticagrelor Study
Major heart attacks are caused by a number of factors, the two major of which are furring up of a coronary artery with atheroma and then sudden clot formation on this area leading to a blockage and interruption of blood flow.
- Conditions
- Acute Coronary Syndrome (ACS), High On-treatment Platelet Reactivity (HTPR), Microvascular Obstruction (MVO), ST-segment Elevation Myocardial Infarction (STEMI)
- Trial name
- NCT02733341
- Testing
- Cangrelor, Ticagrelor
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Postoperative Pain
Virtual Reality in Postoperative Acute Pain Management in Thoracic Surgery
This randomized controlled study is to investigate the effectiveness of VR headsets in reducing postoperative pain intensity among patients after having undergone thoracic surgical procedures.
- Trial name
- VRThx (NCT06097520)
- Testing
- VR Intervention
- Where
- Switzerland
- Volunteers
- 39 people
- Sponsor
- University Hospital, Basel, Switzerland
Postoperative Pain, Kidney Transplant; Complications
Thread Embedding Acupuncture vs Sham on Acute Pain and Quality of Life After Laparoscopic Nephrectomy of Living Donor
This randomized, double-blind controlled study aims to evaluate the effectiveness of thread implantation acupuncture at EX-B2 L1 in reducing postoperative pain and improving quality of life in patients undergoing laparoscopic…
- Trial name
- NCT07243301
- Testing
- Thread implantation acupuncture
- Where
- Indonesia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Pain, Head, Pain, Acute
Single-Dose Bioavailability Study of Two Formulations of Ibuprofen and Pseudoephedrine Hydrochloride Tablets
Evaluation of the comparative bioavailability between two oral formulations containing ibuprofen 200 mg and pseudoephedrine 30 mg after a single dose in healthy subjects under fasting conditions.
- Conditions
- Pain, Head, Pain, Acute, Pain, Back, Fever
- Trial name
- NCT03429738
- Testing
- Ibuprofen/Pseudoephedrine HCl 200/30 mg Film-Coated Tablets, RhinAdvil Rhume 200 mg/30 mg Film-Coated Tablets
- Where
- Canada
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Postoperative Pain
Risk Factors and a Predictive Nomogram for Acute Moderate-to-severe Postoperative Pain After Achilles Tendon Surgery
This is a single-center retrospective cohort study to identify independent risk factors and develop a predictive nomogram for moderate-to-severe pain within 24 hours after Achilles tendon surgery.
- Trial name
- NCT07558512
- Testing
- No Study-Specific Intervention
- Where
- China
- Volunteers
- 489 people
- Sponsor
- Min Li
Pain, Acute, Opioid Misuse
The Effect of a Charcoal Deactivation Pouch on Opioid Disposal After Cesarean Delivery
Background: There is scarce literature investigating how patients dispose of unused opioid supplies after their cesarean postoperative pain has faded.
- Conditions
- Pain, Acute, Opioid Misuse, Obstetric Pain, Cesarean Section Complications
- Trial name
- NCT05498025
- Testing
- Deterra activated charcoal pouch
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Single Traumatic Limb Injury With Severe Pain (Score > 5/10 on Numerical Pain Scale)
Intranasal Sufentanil Pain-management at Entrance of Emergency Department : Influence on Pain-relief Delay
Non-invasive and simple, intranasal (IN) route of administration seems promising for pain management in the Emergency Department (ED), especially when used precociously by triage nurse to rapidly deliver the first opioid dose to…
- Trial name
- InSPEED (NCT01954368)
- Testing
- Sufentanil
- Where
- France
- Volunteers
- 144 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Acute Myocardial Infarction
Place of Copeptin-troponin Assay in the Elimination Diagnosis of Non-ST+ ACS
The aim of this study is to demonstrate that a combined troponin and copeptin assay can exclude non-ST+ ACS in patients with chest pain less than 6 hours old.
- Trial name
- CopSCA (NCT05902117)
- Testing
- Troponin and Copeptin assay
- Where
- 2 sites in France
- Volunteers
- 270 people
- Sponsor
- Hôpital NOVO
Acute Pain
Acupuncture Versus Intravenous Morphine in the Management of Acute Pain in the Emergency Department
Inadequate pain management is a common problem encountered in ED settings. Pain relief medications use is often limited by their side effects.
- Trial name
- AcuMAP (NCT02460913)
- Testing
- Acupuncture, Morphine titration
- Volunteers
- 300 people
- Sponsor
- University of Monastir
Hallux Valgus
A Study to Evaluate the Effectiveness and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain From Bunionectomy Compared With Placebo
The purpose of this study is to evaluate the analgesic efficacy and safety of tapentadol immediate-release (IR [CG5503]) for use in the relief of moderate to severe acute pain, compared with placebo, in adult Taiwanese patients…
- Trial name
- NCT01813890
- Testing
- Tapentadol IR 50 mg, Tapentadol IR 75 mg
- Where
- 3 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- Janssen-Cilag International NV
Acute Post-thoracotomy Pain
Peri-neural Dexmedetomidine as an Adjuvant to Bupivacaine Induced Paravertebral Block in Patients Undergonig Thoracotomy
This study evaluates the effect of adding dexmedetomidine as an adjuvant to bupivacaine in patients undergoing thoracotomy when administered peri-neurally in thoracic paravertebral space.
- Trial name
- NCT02397603
- Testing
- dexmedetomidine bupivacaine, Bupivacaine saline
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
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