Clinical trials: Acute Pain, completed
Dental Pain
Evaluation of the Efficacy and Safety of Diclofenac HPBCD 25, 50 mg/ml in the Treatment of Post-surgical Pain Following Dental Surgery
The present study is proposed to evaluate the efficacy and safety of single doses of Diclofenac HPBCD subcutaneous (s.c.) (25 mg/1 ml and 50 mg/1 ml) in the treatment of acute moderate-to-severe pain after dental impaction…
- Trial name
- NCT00942448
- Testing
- Diclofenac HPBCD
- Where
- 6 sites in Poland, United Kingdom
- Volunteers
- 306 people
- Sponsor
- IBSA Institut Biochimique SA
Acute Coronary Syndrome
A Prospective Pilot Study to Evaluate a New Marker of Ischemia in Chest Pain Triage
A Single-center prospective pilot study enrolling chest pain patients. CD 26 measurement will be performed and compared to troponin µs for early triage of these patients.
- Trial name
- NCT02608255
- Testing
- blood samples
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Acute Postoperative Pain, Chronic Postoperative Pain
Femoral and Epidural Block After Total Knee Arthroplasty
Total knee prosthetic replacement causes severe postoperative pain. Various analgesic techniques have been used in pain control.
- Trial name
- NCT02115945
- Testing
- DN4 test, The SF 12 test, HAD scale
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Pharyngitis
Safety and Efficacy of a Sore Throat Lozenge DORITHRICIN in Patients With Acute Pharyngitis
The aim of this multi-center, randomized, double-blind, placebo-controlled trial is to compare the efficacy and safety of Dorithricin® lozenge - a triple combination of 0.5 mg tyrothricin, 1.0 mg benzalkonium chloride, and 1.5 mg…
- Trial name
- DoriPha (NCT03323528)
- Testing
- Benzalkonium Chloride-Benzocaine Topical
- Where
- Germany
- Volunteers
- 321 people
- Sponsor
- Medice Arzneimittel Pütter GmbH & Co KG
Acute Chest Pain, Acute Coronary Syndrome
The Evaluation and Management of Patients With Acute ChesT Pain in China
EMPACT is the first attempt to comprehensively evaluate the current emergency care of acute chest pain from a regional representative sample in China.Findings will allow new opportunities to facilitate the clinical quality…
- Trial name
- EMPACT (NCT02536677)
- Where
- China
- Volunteers
- 8,374 people
- Sponsor
- Yuguo Chen
Breast Surgery
ER-One: A Double-blind Trial of Erector Spinae Block (ESP) Versus Paravertebral Block (PVB) Before Breast Cancer Surgery
The block (ESP or PVB) will be performed preoperatively in the recovery room under standard monitoring. After setting a peripheral venous access, patient will be installed on lateral decubitus position on the opposite side of the…
- Trial name
- ER-One (NCT04827030)
- Testing
- Ropivacaïne Hydrochloride by Erector Spinae block, Ropivacaïne Hydrochloride by Paravertebral block
- Where
- 5 sites in France
- Volunteers
- 292 people
- Sponsor
- Institut Curie
Pain
Safety and Tolerability of Zipsor® in Pediatric Subjects (Ages 12-17 Years) With Mild to Moderate Acute
As part of the PREA(Pediatric Research Equity Act) commitment, the objective of the study is to confirm safety and tolerability of 25 mg of Zipsor® in clinical pediatric subjects.
- Trial name
- NCT01982539
- Testing
- Zipsor®
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Depomed
Myocardial Infarction, Angina, Unstable
Advantageous Predictors of Acute Coronary Syndromes Evaluation (APACE) Study
The triage of patients with suspected acute coronary syndrome in the emergency room is a time-consuming diagnostic challenge. Therefore high sensitive early markers for myocardial damage are needed for more rapidly rule out of…
- Trial name
- APACE (NCT00470587)
- Where
- 13 sites in Czechia, Italy and 3 more
- Volunteers
- 10,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Kidney Transplantation, Anxiety
The Effects of Pre-operative Anxiety on Anesthetic Recovery and Post-operative Pain in Donor Nephrectomy
Kidney transplant is the most effective choice of treatment for patients with end-stage kidney failure in terms of quality of life and longevity. Today, 20-25% of kidney transplantations are implemented with living donors.
- Conditions
- Kidney Transplantation, Anxiety, Pain, Acute, Anesthesia Recovery Period
- Trial name
- NCT03131258
- Testing
- Donor Nephrectomy
- Volunteers
- 48 people
- Sponsor
- Ege University
Pain, Pain, Postoperative
Prediction and Characterization of Acute and Chronic Postoperative Pain
Despite enormous progress insufficient postoperative pain management remains a frequent problem in the early postoperative phase after surgery.
- Conditions
- Pain, Pain, Postoperative, Funnel Chest
- Trial name
- NCT01308385
- Testing
- Conditioned pain modulation
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- University of Aarhus
Acute Nociceptive Pain, Hyperalgesia
Pain Response to Cannabidiol in Opioid-induced Hyperalgesia, Acute Nociceptive Pain and Allodynia By Using a Model Mimicking Acute Pain in Healthy Adults
Prospective, randomized, placebo-controlled, double-blinded, crossover study to investigate the effect of cannabidiol (CBD) on remifentanil-induced hyperalgesia in healthy volunteers in a well-established acute pain model.
- Conditions
- Acute Nociceptive Pain, Hyperalgesia, Allodynia, Opioid-induced Hyperalgesia
- Trial name
- CANAB II (NCT04059978)
- Testing
- CBD, Remifentanil
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Muscle Soreness
Effect Kinesio Taping on Acute-onset Muscle Soreness and Calf Muscle Extensibility Among Endurance Athletes
In recent years, athletes have frequently utilized Kinesio tape (KT) to enhance their performance. Despite widespread use, data regarding its efficacy and mechanism of action is lacking among healthy endurance athletes.
- Trial name
- NCT05564585
- Testing
- Kinesio Taping
- Where
- Saudi Arabia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- AMIR IQBAL
Otitis Externa, Otorhinolaryngologic Diseases
Safety and Efficacy Study of Foam Otic Cipro Compared to a Standard Solution ( Ciloxan - Alcon Labs ) to Treat Acute Otitis Externa
The purpose of this study is to assess the Safety and Efficacy of Foam Otic Cipro, a novel medication developed to treat Acute Diffuse Otitis Externa of bacterial origin.
- Conditions
- Otitis Externa, Otorhinolaryngologic Diseases, Ear Diseases, Otitis
- Trial name
- NCT00872209
- Testing
- 0.3% Ciprofloxacin Ear Drops, 0.3% Ciprofloxacin Foam Otic Cipro
- Where
- 4 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Otic Pharma
Chronic Back Pain
The Acute Effect Of Different Kinesiological Tape
This study aims to compare the acute effects of different kinesiology tapes on pain, functional performance and trunk endurance in young adults with chronic low back pain.
- Trial name
- NCT05167214
- Testing
- The Acute Effect Of Different Kinesiological Tape Application On Pain, Functional Performance And Trunk Endurance In Young Adults With Chronic Back Pain
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Baskent University
Soft Tissue Injuries, Contusions
Efficacy and Safety of Esflurbiprofen Hydrogel Patch in the Treatment of Local Acute Pain
Objective of this study is: to determine efficacy and safety of a Esflurbiprofen Hydrogel Patch compared to placebo in patients with acute strains, sprains or bruises of the extremities following blunt trauma, e.g.
- Conditions
- Soft Tissue Injuries, Contusions, Strains, Sprains
- Trial name
- NCT04908748
- Testing
- Esflurbiprofen Hydrogel Patch
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Teikoku Seiyaku Co., Ltd.
Musculoskeletal Pain, Acute Pain
BFA Treatment of Pain
The aim of this pilot study is to conduct an unblinded pilot randomized clinical study on the effectiveness and tolerability of auricular semi-permanent (ASP) vs intradermal (long), and pyonex needles in Battlefield Acupuncture…
- Trial name
- NCT04464954
- Testing
- Auricular semi-permanent (ASP gold) needles, Intradermal (long) needles using J-type No. 2 (.18)x 15mm, Pyonex needles (Seirin Yellow 0.2 x 0.6mm)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Paul Crawford
Acute Appendicitis
Laparoscopic-Assisted TAP Block VErsus Trocar-site Infiltration After Laparoscopic Appendectomy
This randomized controlled trial compared laparoscopic-assisted transversus abdominis plane (TAP) block with trocar-site local anesthetic infiltration for postoperative pain management in adult patients undergoing laparoscopic…
- Trial name
- NCT07849751
- Testing
- laparoscopic-assisted transversus abdominis plane block, trocar-site local anesthetic infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Plantar Fascitis, Pain
Comparison of the Acute Effects of Focused and Radial ESWT on Pain and Balance Performance in Individuals With Plantar Fasciitis: A Randomized Clinical Trial
This study aimed to compare the acute effects of focused and radial ESWT on pain and balance performance in individuals with plantar fasciitis.
- Trial name
- ESWT (NCT06685172)
- Testing
- f-ESWT, r-ESWT
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gulhane Training and Research Hospital
Postoperative Pain, Acute
Comparison of Erector Spinae Plane Block and Rectus Sheath Block
In study, The investigators aimed to compare the intraoperative and postoperative analgesic efficacy of erector spinae plane block and rectus sheath block, which investigators routinely perform in surgeries with abdominal lover…
- Trial name
- NCT05225766
- Testing
- bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uludag University
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Israel Satellite Registry
BIOTRONIK - SaFety and Performance Registry for a diabetic patient population with the .bimus Eluting Orsiro Stent System Within daily clinical practice - III
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Diabetes Mellitus Type 1 or 2
- Trial name
- NCT01895712
- Where
- 6 sites in Israel
- Volunteers
- 120 people
- Sponsor
- BIOTRONIK Israel
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