Clinical trials: Acute Pain, completed
Pain
Blood Sample Donations to Study the Role of Genes in Pain
This study attempts to identify genes that may increase or decrease the likelihood of sciatic pain (shooting pain down the leg) persisting 1 year after treatment of a herniated spinal disc.
- Trial name
- NCT00341367
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Pain
Comparison of Two Dosage Strengths of Transdermal Fentanyl Versus Transdermal Buprenorphine and Placebo in Acute Pain Models in Healthy Volunteers.
The primary objective of this pilot trial is to identify pain model(s) which allow(s) to compare and differentiate the analgesic effects between transdermal fentanyl 25µg/h, transdermal fentanyl 12µg/h and placebo in a dose…
- Trial name
- NCT00886002
- Testing
- Fentanyl; Buprenorphine; Naloxone
- Volunteers
- 20 people
- Sponsor
- Janssen-Cilag A.G., Switzerland
Hydromorphone Use, Acute Postoperative Pain
Methadone and Hydromorphone For Spinal Surgery
Patients undergoing major spinal surgery continue to experience moderate-to-severe pain during the first 2-3 days following the operative procedure.
- Conditions
- Hydromorphone Use, Acute Postoperative Pain, Patient Satisfaction, Chronic Persistent Surgical Pain
- Trial name
- NCT02107339
- Testing
- Methadone, Hydromorphone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Pain, Postoperative Pain
REduced Pain After Bariatric Surgery - Gastric Bypass
This study aims to analyze the effect of laparoscopic guided transversus abdominis plane (LG-TAP) block compared to placebo for postoperative analgesia following laparoscopic gastric bypass.
- Conditions
- Pain, Postoperative Pain, Acute Pain, Analgesia
- Trial name
- REPABS-BPG (NCT06614257)
- Testing
- LG-TAP block with local anesthetic, Port site infiltration, LG-TAP block with saline solution
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Acute Pain
Efficacy and Safety of Oxymorphone Immediate Release in Post-surgical Acute Pain
The purpose of this study is to evaluate the analgesic efficacy and safety of two doses of oxymorphone immediate release (IR) compared to placebo and oxycodone in post-surgical pain.
- Trial name
- NCT00226395
- Testing
- Oxymorphone immediate release
- Where
- 21 sites in United States
- Volunteers
- 320 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Myocardial Ischemia
Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST Elevation Acute Coronary Syndromes
MERLIN-TIMI 36 is a multi-national, double-blind, randomized, placebo-controlled, parallel-group clinical trial designed to evaluate the efficacy and safety of ranolazine during acute and long-term treatment in approximately…
- Trial name
- NCT00099788
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 6,560 people
- Sponsor
- Gilead Sciences
Pain Acute, Acupuncture
Acupuncture for Pain Management During Uterine Aspiration
The proposed study will be a randomized, double blinded, placebo-controlled trial to evaluate the efficacy of auricular acupuncture as adjunct for pain management during abortion.
- Trial name
- NCT03391986
- Testing
- SEIRIN® Pyonex™ Acupuncture Needles, 12 mm Plasters
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Columbia University
Surgery, Acute Pain
IPACK and Adductor Canal Catheter Patient Outcomes for TKAs?
This study evaluates the addition of the IPACK block to the adductor canal block and catheter in the pain management of total knee arthroplasty.
- Trial name
- NCT03774966
- Testing
- Adductor Canal Block + Catheter & IPACK block, Adductor canal block + catheter
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Bunionectomy, Orthopedic Surgery
Study of Lornoxicam or Ketorolac or Placebo for Post-Operative Pain After Bunionectomy
To determine whether a single dose of intravenous lornoxicam is superior to intravenous placebo for management of post-operative pain in patients who have surgical removal of a bunion on the lower extremity.
- Trial name
- NCT00293631
- Testing
- Lornoxicam 8 mg, Lornoxicam 16 mg, Ketorolac 30 mg
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- POZEN
Acute Pain
Efficacy, Tolerability, Safety, and Pharmacokinetic Study of DFN-15
Efficacy, Tolerability, Safety and Pharmacokinetic Study of DFN-15 in Post-Surgical Dental Pain.
- Trial name
- NCT03554772
- Testing
- DFN-15 (Celecoxib Oral Solution) 62.5 mg, DFN-15 (Celecoxib Oral Solution) 125 mg, DFN-15 (Celecoxib Oral Solution) 250 mg
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Knee Pain Swelling
Role of Two Rehabilitative Treatments and Diet in the Modulation of Inflammation in Patients With Knee Prosthesis.
The investigators studied the influence of two aproved rehabilitative treatments, connective tissue techniques and lymphatic drainage, on acute inflammation markers.
- Trial name
- NCT04580069
- Testing
- Lymphatic drainage
- Where
- 2 sites in Italy
- Volunteers
- 34 people
- Sponsor
- Presidio Ospedaliero di Asiago
Pain
Safety and Tolerability of Zipsor® in Pediatric Subjects (Ages 12-17 Years) With Mild to Moderate Acute
As part of the PREA(Pediatric Research Equity Act) commitment, the objective of the study is to confirm safety and tolerability of 25 mg of Zipsor® in clinical pediatric subjects.
- Trial name
- NCT01982539
- Testing
- Zipsor®
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Depomed
Acute Pain
Effect of Early Pain Management at Triage on Opioid Consumption
introduction: Pain remains one of the most common reasons of emergency department admission. Opioids are overprescribed in emergency departments to treat severe pain.
- Trial name
- NCT03243006
- Testing
- Paracetamol, Tramadol/Paracetamol combination
- Volunteers
- 1,500 people
- Sponsor
- University of Monastir
Pain, Acute
Music for Pain in the Waiting Room
This is a single-site, three-arm, parallel-group randomized clinical trial (RCT). The clinical effects of two, 4-minute, audio-recorded, music interventions (one with lyrics and the other without) for orthopedic patients will be…
- Trial name
- NCT06511843
- Testing
- Pain Coping Information, Lyrical Music, Instrumental Music
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Florida State University
Physiological Parameter, Acute Pain
The Effect of Turkish Music and Comedy Film on Pain, Vital Signs and Cortisol Level in Orthopedic Patients
The aim of this thesis is; It was planned to determine the effect of Turkish music and comedy films on pain, vital signs and cortisol levels of patients who had orthopedic surgery. The research is a randomized controlled study.
- Trial name
- NCT04755114
- Testing
- Turkish Music, comedy movie
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Inonu University
Post-operative Pain
Effect of Local Infiltration Analgesia in Total Hip Arthroplasty
The purpose of the study is to compare the effects of per-operative local infiltration analgesia with ropivacaine 0,2 % (150 ML) versus placebo on acute postoperative pain intensity after total hip arthroplasty.
- Trial name
- NCT00968955
- Testing
- Ropivacaine
- Where
- 2 sites in Denmark
- Volunteers
- 120 people
- Sponsor
- Hvidovre University Hospital
Back Pain
Effectiveness of Iliopsoas Positional Release Versus Conventional Exercises in the Management of Sub-acute Back Pain.
Recommended treatment for chronic non-specific LBP is exercise therapy, behavioral therapy including pain management, or a combination of these; There is not enough evidence to establish recommendations for which one is the most…
- Trial name
- NCT06267404
- Testing
- Iliopsoas Positional release therapy, Conventional exercises
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- University of Karachi
Acute Pain
Is There an Ideal Dose of Intravenous Fentanyl in the Prehospital Setting
In a previous study the investigators evaluated the apparent efficacy and safety of intravenous fentanyl administered by ambulance personnel and found that 58.4% (CI 56.4-60.4) out of 2348 prehospital patients treated with…
- Trial name
- NCT02914678
- Testing
- Fentanyl
- Volunteers
- 7,093 people
- Sponsor
- University of Aarhus
Myocardial Infarction, Angina, Unstable
Advantageous Predictors of Acute Coronary Syndromes Evaluation (APACE) Study
The triage of patients with suspected acute coronary syndrome in the emergency room is a time-consuming diagnostic challenge. Therefore high sensitive early markers for myocardial damage are needed for more rapidly rule out of…
- Trial name
- APACE (NCT00470587)
- Where
- 13 sites in Czechia, Italy and 3 more
- Volunteers
- 10,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Acute Otitis Media
Four Arm Safety & Efficacy With Antipyrine and Benzocaine Otic Solution in Children With Acute Otitis Media
The primary objective is to compare the effect of treatment with a combination of ear solutions on the reduction of pain symptoms at 1 hour after dosing in children with acute otitis media.
- Trial name
- NCT02037893
- Testing
- Antipyrine and Benzocaine otic solution, Antipyrine Otic Solution, Benzocaine Otic Solution
- Where
- 10 sites in United States
- Volunteers
- 112 people
- Sponsor
- Currax Pharmaceuticals
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