Clinical trials: Acute Pancreatitis
Post-ERCP Acute Pancreatitis
The Prophylactic Effect of Stilamin on Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis
Pancreatitis are one of the most common complications of post-ERCP (Endoscopic Retrograde Cholangiopancreatography), the incidence rate is 5\&-10%, how to prevent PEP and hyperamylasemia is an important issue, somatostatin is…
- Trial name
- NCT01431781
- Testing
- Stilamin+common daily treatment, Common daily practice
- Where
- 15 sites in China
- Volunteers
- 908 people
- Sponsor
- Changhai Hospital
Acute Pancreatitis (AP), Diabetes Mellitus
Hyperglycemia and Acute Pancreatitis
The goal of this observational study is to learn about post-acute pancreatitis diabetes mellitus (PPDM-A). The main questions it aims to answer are: 1. What are the clinical characteristics of PPDM-A? 2.
- Trial name
- NCT06590233
- Volunteers
- 4,500 people
- Sponsor
- Shanghai Changzheng Hospital
Cholecystitis, Acute, Acute Cholangitis
Visualization of the Extrahepatic biliaRy Tree Trial
This study is a prospective randomized controlled trial evaluating the use of a fluorescent dye, indocyanine green (ICG), in the identification of important bile duct anatomy during emergent same-admission cholecystectomy.
- Conditions
- Cholecystitis, Acute, Acute Cholangitis, Gallstone Pancreatitis, Choledocholithiasis
- Trial name
- VERT (NCT04922528)
- Testing
- Laparoscopic Cholecystectomy with Fluorescent Cholangiography, Laparoscopic Cholecystectomy with White Light Imaging
- Where
- Canada
- Volunteers
- 340 people
- Sponsor
- University of British Columbia
Severe Hypertriglyceridemia (sHTG), Hypertriglyceridemia
A Phase III Study to Evaluate the Efficacy and Safety of of DR10624 in Subjects With Severe Hypertriglyceridemia
This is a multicenter, randomized, double-blind, placebo-controlled Phase 3 clinical trial to assess the efficacy and safety of weekly subcutaneous DR10624 injection in adult patients with severe hypertriglyceridemia (sHTG).
- Trial name
- NCT07693777
- Testing
- DR10624 Injection
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Zhejiang Doer Biologics Co., Ltd.
Coronary Artery Disease, Congestive Heart Failure
Prognostic Indicators as Provided by the EPIC ClearView
The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation
- Trial name
- GBMC (NCT01476995)
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Chronic Pancreatitis, Acute Recurrent Pancreatitis
Internet Based Cognitive Behavioral Therapy in Pediatric Chronic Pancreatitis
Abdominal pain is common in children with chronic and acute recurring pancreatitis (CP, ARP), and as they continue into adulthood, the disease progresses with increased pain and greater exposure to opioids.
- Trial name
- NCT03707431
- Testing
- Web-based CBT, Pain Education
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Seattle Children's Hospital
Pancreatitis, Acute
A Long-term Safety Follow-up Study of SCM-AGH in Patients Who Completed SCM-APT2001 Study
This is a long-term safety follow-up study of the Phase I/IIa multicenter study of SCM-AGH in subjects with moderate to severe acute pancreatitis.
- Trial name
- NCT05955235
- Testing
- Not Applicable(Observation Study)
- Where
- 6 sites in South Korea
- Volunteers
- 42 people
- Sponsor
- SCM Lifescience Co., LTD.
Pancreatitis Biliary, Pancreatitis Acute Biliary
Indomethacin for Biliary ERCP Patients
This study is a randomized clinical trial evaluating the efficacy of rectal indomethacin in preventing post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis in patients undergoing biliary ERCP who have a history…
- Conditions
- Pancreatitis Biliary, Pancreatitis Acute Biliary, Pancreatitis, Post-ERCP Pancreatitis
- Trial name
- NCT07661498
- Testing
- indomethacin
- Where
- United States
- Volunteers
- 860 people
- Sponsor
- University of California, San Francisco
Post-ERCP Acute Pancreatitis
Low-acid Contrast Media for Preventing Post ERCP Pancreatitis
Title： Low-acid contrast media for preventing post ERCP pancreatitis: a multicenter, retrospective, cohort study (LAMP-R) . Objective: Main objective: This study aims to determine whether low-acid contrast media can reduce the…
- Trial name
- LAMP-R (NCT07391787)
- Testing
- Ioversol, Iopromide, Iohexol
- Where
- 2 sites in China
- Volunteers
- 3,979 people
- Sponsor
- Shandong University
Acute Pancreatitis
Dachaihu Decoction Compound and Rhubarb Single Medicine in the Treatment of Acute Pancreatitis
A large number of clinical studies have shown that oral administration, external application or enema of Chinese medicine can promote the recovery of gastrointestinal function and the absorption of pancreatic inflammation.
- Trial name
- NCT04990336
- Testing
- Dachaihu decoction compound, Rhubarb single medicine, Regular therapies
- Volunteers
- 306 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Pancreatitis, Acute, Pain, Acute
Comparison of the Effectiveness of Paracetamol With Ibuprofen or Paracetamol With Metamizole in Treating Pain in Acute Pancreatitis in Children
The aim of the study is to assess the effectiveness and tolerance of pain treatment in AP in children using intravenous paracetamol in combination with ibuprofen or paracetamol in combination with metamizole.
- Conditions
- Pancreatitis, Acute, Pain, Acute, Pancreatic Disease, Pancreatic Diseases
- Trial name
- NCT07024199
- Testing
- The initial pain assessment, Drug administration according to protocol (paracetamol + ibuprofen OR paracetamol + metamizol), The effectiveness of the treatment
- Where
- Poland
- Volunteers
- 78 people
- Sponsor
- Medical University of Warsaw
Pancreatitis, Pancreatitis, Acute Necrotizing
Dual-scopic Pancreatic Necrosectomy (DPN)
The LPN procedure is performed under general anesthesia. The transperitoneal access to peripancreatic space is via the gastro-colic ligament and greater omentum, effusion and pus is removed by laparoscopic forceps and suction.
- Conditions
- Pancreatitis, Pancreatitis, Acute Necrotizing, Pancreatic Diseases
- Trial name
- NCT04443595
- Testing
- Dual-scopic pancreatic necrosectomy（DPN）
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First People's Hospital of Hangzhou
Acute Pancreatitis (AP), Vagus Nerve Stimulations
Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Acute Pancreatitis
Acute pancreatitis (AP), characterized by the sudden onset of pancreatic inflammation, is a frequent gastrointestinal emergency. Early suppression of the inflammatory response is critical to mitigate disease progression.
- Trial name
- NCT06998784
- Testing
- taVNS
- Where
- 5 sites in China
- Volunteers
- 60 people
- Sponsor
- Air Force Military Medical University, China
Bedside Placement of Nasal Jejunal Tube
A Trial of Bedside Placement of Nasal Jejunal Tube Confirmed by Ultrasound Compared to Placement by Endoscope in Patients With SAP
The investigators assessed the utility of ultrasonography in confirming the position of nasal jejunal tube after bedside placement when compared with endoscopic placement in patients with severe acute pancreatitis.
- Trial name
- SAP (NCT02456155)
- Testing
- placing nasal jejunal tube with ultrasound, placing nasal jejunal tube endoscopically
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Li Gang
Recurrent Acute Pancreatitis, Prevention
The Effect of Aspirin on Recurrent Acute Pancreatitis
Recurrent acute pancreatitis (RAP) was defined as two or more occurrences of acute pancreatitis, which was associated with higher percentages of morbidities and mortalities, lower patients' life quality and increased health-care…
- Conditions
- Recurrent Acute Pancreatitis, Prevention, Aspirin
- Trial name
- NCT06185621
- Testing
- 100mg aspirin
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Air Force Military Medical University, China
Acute Pancreatitis, Intra-abdominal Hypertension
Neostigmine Treatment of Acute Pancreatitis Combined With Intra-abdominal Hypertension
Acute pancreatitis(A) often complicated with Intra-abdominal Hypertension. After the onset of acute pancreatitis, capillary leakage causing ascites,upper gastrointestinal tract obstruction and paralytic ileus leading to an…
- Trial name
- NCT02543658
- Testing
- Neostigmine Methylsulfate 1 MG/ML, Conservative treatment
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Acute Biliary Pancreatitis
Early EUS in Acute Biliary Pancreatitis
Acute biliary pancreatitis (ABP) is a potentially life-threatening condition caused by common bile duct (CBD) stones or sludge, which requires prompt diagnosis and treatment by endoscopic removal of the material.
- Trial name
- NCT02430285
- Testing
- Endoscopic Ultrasound, Olympus 180 series echoendoscope
- Where
- Italy
- Volunteers
- 181 people
- Sponsor
- Istituto Clinico Humanitas
Pancreatitis
Abstats: Computer-aided, Non-invasive, Acoustic Gastrointestinal Surveillance (AGIS) in Acute Pancreatitis
The purpose of this study is to conduct a pilot test of an abdominal acoustic sensor on patients with acute pancreatitis to determine the correlation of acoustic signals with symptoms reported by the patient.
- Trial name
- NCT02412826
- Testing
- Abstats sensor
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Acute Pancreatitis, Recurrent Acute Pancreatitis
Preventing the Recurrence of Acute Pancreatitis by Alcohol and Smoking Cessation
Recurrence of acute pancreatitis (AP) is often facilitated by regular alcohol consumption and smoking. An applied lifestyle intervention focusing on the cessation of alcohol consumption and smoking might prevent the recurrence of…
- Trial name
- REAPPEAR (NCT04647097)
- Testing
- Standard intervention only, Standard intervention plus repeated intervention
- Where
- Hungary
- Volunteers
- 364 people
- Sponsor
- University of Pecs
Pancreatitis, Acute, Hyperglycaemia
Glucose Levels in Acute Pancreatitis and the Impact of Insulin Depletion and Bacterial Endotoxaemia
There are currently no early predictive biomarkers for severity of acute pancreatitis (AP) that would allow stratification of patients for potential early interventional therapies.
- Trial name
- GLIDE (NCT06972238)
- Volunteers
- 30 people
- Sponsor
- Manchester University NHS Foundation Trust