Clinical trials: Acute Post-surgical Pain
Post Operative Pain, Acute, Sedation Score
Patient Control Epidural Versus Conventional Epidural.
As one of the complications of THR is post operative pain, which usually requires epidural catheter insertion. We are comparing the effect of patient control epidural versus conventional epidural for patient's satisfaction.
- Conditions
- Post Operative Pain, Acute, Sedation Score, Degree of Motor Block, Length of Hospital Stay
- Trial name
- NCT06721000
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College
Post Operative Pain, Chronic Pain
Performance and Safety of the ANTALGEEK® Thess Monitoring Medical Device in the Outpatient Management of Acute Pain and Postoperative Recovery
Acute postoperative pain (APOP) is a major public health problem, affecting nearly 10 million patients in France each year. Effective analgesic therapy in the first postoperative week is a key factor in reducing early…
- Trial name
- TRACE (NCT07680998)
- Testing
- Post-operative follow-up using the Thess Telemonitoring device in conjunction with the ANTALGEEK® protocol
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Circadian Rhythm, Postoperative Pain
The Effect of Circadian Rhytm on Postoperative Pain Undergoing Pediatric Surgery
These circadian rhythms are self-sustained, endogenous oscillations generated by circadian clocks that persist with a period of around 24 -h under constant conditions.
- Trial name
- NCT05379192
- Testing
- Group 1, Group 2, Group 3, Group 4
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Faruk Cicekci
Pain, Postoperative
The Interest of the Xylocaine® and Ketamine on the Management of Acute and Chronic Ain After Colectomy by Laparoscopy
Recent clinical studies in abdominal surgery have shown that the use of Xylocaine® parenterally intraoperative at plasma concentrations below the toxic threshold of 5 .mu.g / ml, had an analgesic effect and decreased…
- Trial name
- KETALIDO (NCT02969733)
- Testing
- Xylocaine, Ketamine, isotonic saline serum intravenous administration
- Where
- France
- Volunteers
- 135 people
- Sponsor
- University Hospital, Lille
Arthroplasty, Replacement, Knee, Anesthesia, Conduction
Adductor Canal Vs Adductor Canal Plus SPANK Block for Postoperative Pain in Knee Arthroplasty Surgery
This study will prospectively investigate the efficacy of Adductor canal block with periarticular infiltration Vs Adductor canal block, Periarticluar infiltration and Sensory posterior articular nerve of the knee block in…
- Conditions
- Arthroplasty, Replacement, Knee, Anesthesia, Conduction, Acute Pain
- Trial name
- NCT04290442
- Testing
- adductor canal block, SPANK, Ropivacaine
- Where
- United States
- Sponsor
- Bruce Ben-David
Acute Toothache Patients Above Moderate Pain After Teeth Extraction Surgery
Phase 3 Study of Tramadol Hydrochloride/Acetaminophen SR Tab. & Tramadol Hydrochloride/Acetaminophen Tab. in Acute Toothache Patients After Teeth Extraction Surgery
A randomized, double-blind, active-controlled, parallel, multicenter Phase 3 study of Tramadol hydrochloride/Acetaminophen SR Tab. \& Tramadol hydrochloride/Acetaminophen Tab.
- Trial name
- NCT01920386
- Testing
- Tramadol hydrochloride/Acetaminophen Tab., Tramadol hydrochloride/Acetaminophen SR Tab.
- Volunteers
- 240 people
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Acute Postoperative Pain
Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profile of HYR-PB21 in Healthy Volunteers
This study is the first time into human study (FTIH) for HYR-PB21 for injection. The study will evaluate the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending and single subcutaneous dose of HYR-PB21 for…
- Trial name
- NCT04169256
- Testing
- HYR-PB21, Liposomal bupivacaine, Normal Saline
- Where
- Australia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fruithy Medical Pty Ltd
Primary Inguinal Hernia
The Effect of Preemptive Regional Anesthesia (TAP-block) on Acute and Chronic Pain After Transabdominal Preperitoneal Inguinal Hernia Repair (TAPP)
The study is devoted to the impact of preemptive regional Transversus abdominal plane block on the postoperative acute and chronic pain after elective Transabdominal preperitoneal (TAPP) inguinal hernia repair.
- Trial name
- ERA-TAPP (NCT06406959)
- Testing
- Transversus abdominal plane block (TAP block)
- Where
- Russia
- Volunteers
- 78 people
- Sponsor
- Pirogov Russian National Research Medical University
Pain, Ketamine Adverse Reaction
Cardiovascular Safety After Continuous Ketamine Infusion
Observational study that evaluate the cardiovascular and neuropsychiatric side effects of ketamine analgesic infusions for acute pain
- Conditions
- Pain, Ketamine Adverse Reaction, Postoperative Pain
- Trial name
- NCT03979105
- Testing
- Ketamine
- Where
- 2 sites in Colombia
- Volunteers
- 300 people
- Sponsor
- Universidad de Antioquia
Acute Post Operative Pain, Laparotomy
PIB for Post-operative Analgesia After Laparotomy : Determining the Optimum Dose
Pain control after surgery is a crucial component of postoperative recovery. Thus, in open abdominal surgery, the use of TEA (Thoracic epidural analgesia) has become a gold standard.
- Conditions
- Acute Post Operative Pain, Laparotomy, Epidural Analgesia
- Trial name
- PIBDOSE (NCT05534945)
- Testing
- Programmed intermittent epidural bolus 5 ml, Programmed intermittent epidural bolus 6 ml, Programmed intermittent epidural bolus 7 ml
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Gallbladder Inflammation
Vitamin C Efficacy in Reducing Post Operative Pain
Opioids are the corner stone in the treatment of post operative pain. Because of the several side effects of opiods, non-steroidal anti-inflammatory drugs are usually added postoperatively to decrease the total requirements of…
- Trial name
- NCT01322061
- Testing
- Ascorbic Acid
- Where
- Lebanon
- Volunteers
- 80 people
- Sponsor
- American University of Beirut Medical Center
Acute Postoperative Pain, Lower Limb Surgery
Tapentadol vs Pregabalin for Postoperative Pain in Lower Limb Surgery
This pilot randomised controlled trial compared 72-hour oral premedication with tapentadol (50 mg every 12 hours) versus pregabalin (75 mg every 24 hours) for preventing acute postoperative pain in 46 patients undergoing elective…
- Trial name
- NCT07587645
- Testing
- Tapentadol, Pregabalin
- Where
- Mexico
- Volunteers
- 46 people
- Sponsor
- ISSSTE Hospital Regional "Gral. Ignacio Zaragoza"
Acute Pain, Spinal Stenosis
Quadro-Iliac vs Thoracolumbar Interfascial Plane Block for Analgesia After Single-Level Lumbar Disc Surgery
The investigators aim to compare the postoperative analgesic efficacy of the classical thoracolumbar interfascial plane block and the Quadro-iliac plane block for postoperative analgesia management after lumbar disc surgery.
- Trial name
- NCT07348419
- Testing
- Quadro-iliac plane block, Classical thoracolumbar interfascial plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Samsun University
Postoperative Pain, Acute, Postoperative Pain, Chronic
Postoperative Pain in Patients Undergoing Scheduled Laparoscopic Intestinal Resection Surgery
This observational prospective study aims to evaluate the postoperative analgesic effect of a regional anesthesia thechnique (TAP block) in patients undergoing scheduled laparoscopic intestinal resection for intestinal cancer.
- Trial name
- TAP (NCT05222789)
- Testing
- TAP
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Mobile Applications, Pain, Postoperative
App for Acute Pain Service in Major Surgery
The app will be installed on the patient's smartphone before surgery. Patients will receive reminders to record their pain intensity and opioid-related side effects at the pre-determined time points until at least 2 days after…
- Conditions
- Mobile Applications, Pain, Postoperative, Smartphone, Patient Satisfaction
- Trial name
- NCT06014918
- Testing
- A new smart device application (Smart APS)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Knee Injuries
Acute Pain and Inflammation After Surgery
The purpose of this study is 1. to observe acute pain after surgery and measure the natural course of inflammatory mediators 2. study pain relieving effects and local anti-inflammatory effects of systemically administered…
- Trial name
- Knemikro01 (NCT00774540)
- Testing
- 1 Ketorolac intraarticular
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Pain, Postoperative, Obstructive Sleep Apnea-hypopnea Syndrome
Postoperative Pain Management on Uvulopalatopharyngoplasty Patients
This is a randomized controlled study, aimed to investigate the effects of dinalbuphine sebacate (DS) on patients having uvulopalatopharyngoplasty (UPPP). DS is a prodrug of nalbuphine, a mixed agonist-antagonist opioid.
- Conditions
- Pain, Postoperative, Obstructive Sleep Apnea-hypopnea Syndrome, Pain, Acute
- Trial name
- NCT05825495
- Testing
- Dinalbuphine sebacate, Routine practice
- Volunteers
- 78 people
- Sponsor
- Li-Jen Hsin
Clavicle Fracture, Postoperative Pain
Effectiveness of Superficial Cervical and Clavipectoral Block for Clavicle Surgery
This study aims to compare two local anesthesia techniques (nerve blocks) for patients undergoing collarbone (clavicle) fracture surgery. Typically, this surgery uses the "Interscalene Block" (ISB) technique.
- Conditions
- Clavicle Fracture, Postoperative Pain, Regional Anesthesia Block
- Trial name
- BSS-BKvsBSS-BI (NCT07548775)
- Testing
- Combination of Superficial Cervical Block and Clavipectoral Block (SCB + CPB), Combination of Superficial Cervical Block and Interscalene Block (SCB + ISB)
- Where
- Indonesia
- Volunteers
- 34 people
- Sponsor
- Udayana University
Postoperative Pain
Risk Factors and a Predictive Nomogram for Acute Moderate-to-severe Postoperative Pain After Achilles Tendon Surgery
This is a single-center retrospective cohort study to identify independent risk factors and develop a predictive nomogram for moderate-to-severe pain within 24 hours after Achilles tendon surgery.
- Trial name
- NCT07558512
- Testing
- No Study-Specific Intervention
- Where
- China
- Volunteers
- 489 people
- Sponsor
- Min Li
Post-operative Pain, Acute, Post-operative Pain
Postoperative Analgesia y After Uniportal Video-assisted Thoracoscopic Surgery
Ultrasound-guided erector spinae plane block (ESPB) is an interfascial blockade during thoracic anesthesia, first described by Forero in 2016, and is highlighted by technically feasibility and less complication rate.
- Conditions
- Post-operative Pain, Acute, Post-operative Pain, Thoracic Diseases, Post-Op Complication
- Trial name
- NCT05242328
- Testing
- Ultrasound-guided erector spinae plane block, surgical thoracoscopic intercostal nerve block
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Cheng-Kung University Hospital