Clinical trials: Acute Primary Angle-closure Glaucoma
Acute Angle-Closure Glaucoma
Efficacy Evaluation and Influencing Factors of Argon Laser Peripheral Iridoplasty in Acute Angle Closure Glaucoma
To investigate the changes of angle structure and intraocular pressure after argon laser peripheral iridoplasty in patients with acute angle closure glaucoma patients whose intraocular pressure could not be controlled by drug…
- Trial name
- NCT04912310
- Testing
- Argon laser peripheral iridoplasty
- Where
- China
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Glaucoma, Angle-closure, Primary, Acute
Phase IIA Double-Masked Randomized Sham-Controlled Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Subjects With Acute Primary Angle-Closure Glaucoma (APACG)
This study will assess any side effects that may occur when QPI-1007 is injected into the eye in subjects with acute primary angle-closure glaucoma, as well as how long it takes for the body to clear the drug.
- Trial name
- NCT01965106
- Testing
- QPI-1007 Injection
- Where
- 8 sites in United States, Singapore and 1 more
- Volunteers
- 46 people
- Sponsor
- Quark Pharmaceuticals
Optic Neuropathy, NAION - Non-Arteritic Ischemic Optic Neuropathy
Clinical Study of FB1001 in Patients
This study is designed for single-center, open-label, dose escalation phase I trial to evaluate the safety and tolerability of a single/multiple intravitreal injection of FB1001 in patients with APACG(Acute Primary Angle-Closure…
- Conditions
- Optic Neuropathy, NAION - Non-Arteritic Ischemic Optic Neuropathy, APAC - Acute Primary Angle Closure, Glaucoma, Angle-Closure
- Trial name
- NCT06506305
- Testing
- FB1001
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Angle Closure Glaucoma
Laser Iridotomy Versus Phacoemulsification in Acute Angle Closure
This is a randomised controlled clinical trial to compare laser peripheral iridotomy (LPI) and primary phacoemulsification with intra-ocular lens implantation (phaco/IOL) in the treatment of acute primary angle-closure glaucoma…
- Trial name
- NCT00350428
- Testing
- Laser Preipheral Iridotomy and phacoemulsification
- Where
- Singapore
- Volunteers
- 70 people
- Sponsor
- Singapore National Eye Centre
Glaucoma
ALPI vs Medical Therapy Effects on Optic Nerve Structure & Function
The aim is to determine which approach, immediate argon laser peripheral iridoplasty or conventional systemic medical treatment efficiently breaks acute angle closure attack without consequent visual morbidities.
- Trial name
- Iridoplasty (NCT00485238)
- Testing
- Argon laser Iridoplasty, Intravenous acetazolamide
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- National University Hospital, Singapore
Chronic Angle Closure Glaucoma, Primary Angle Closure
Sequential Laser Iridotomy Using Argon and Q-Switched 532 nm Frequency Doubled Neodymium Yag Laser: A Pilot Study
Sequential Laser Iridotomy uses argon and Nd:yag laser in the first and second steps, respectively. Using q-switched 532 nm laser in the second step is hypothesized to be as good and effective as the conventional Nd:yag laser…
- Conditions
- Chronic Angle Closure Glaucoma, Primary Angle Closure, Primary Angle Closure Suspect, Fellow Eyes of Acute Angle Closure Glaucoma
- Trial name
- NCT00452998
- Testing
- Q-switched fd Nd:yag in Laser Iridotomy
- Where
- Singapore
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Acute Primary Angle-closure Glaucoma
Corneal Densitometry in Acute Primary Angle Closure Glaucoma
Purpose: Our purpose was to investigate the laser peripheral iridotomy (LPI) induced changes in corneal densitometry in acute primary angle closure glaucoma (PACG) cases during the post-laser 1 month period.
- Trial name
- NCT04254458
- Testing
- Corneal densitometry
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ulucanlar Eye Training and Research Hospital
Glaucoma, Angle-closure
Immediate Anterior Chamber Paracentesis With A 30-Gauge Needle for Acute Primary Angle - Closure
This study was to evaluate the efficacy and safety of immediate anterior chamber paracentesis (ACP) with a 30-gauge needle as an initial treatment for acute primary angle closure (APAC).
- Trial name
- NCT01923454
- Testing
- Paracentesis, Acetazolamide, Peripheral iridotomy
- Where
- Thailand
- Volunteers
- 15 people
- Sponsor
- Siriraj Hospital
Glaucoma, Angle-closure, Primary, Acute
Investigating the Neuroprotective Effect of Cop-1 (Copaxone) in Acute Primary Angle Closure
This is a randomised controlled trial to assess the neuroprotective effect of Cop-1 (Copaxone) in patients with acute primary angle closure (APAC).
- Trial name
- NCT01936129
- Testing
- Copaxone
- Where
- Singapore
- Volunteers
- 196 people
- Sponsor
- Singapore Eye Research Institute
Glaucoma, Acute Primary Angle-closure Glaucoma
Comparison of Anterior Chamber Paracentesis and Conventional Mannitol Infusion in Patients With Primary Acute Angle-closure Glaucoma
The investigators wanted to reported the results of immediate anterior chamber paracentesis (ACP), compared to Mannitol infusion, in patients with acute primary angle-closure glaucoma (PACG).
- Trial name
- NCT01266343
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University WanFang Hospital
Subluxation of Lens
Biometry of Occult Lens Subluxation Misdiagnosed as Primary Acute Angle Closed Glaucoma
In this work, we evaluated the biometry data of lens subluxation inducing acute angle closure which were misdiagnosed as primary angle closure at the first visit, and compared with the data of chronic angle closure glaucoma…
- Trial name
- NCT03752710
- Volunteers
- 183 people
- Sponsor
- Tianjin Medical University Eye Hospital
Acute Ocular Hypertension Glaucoma, Intraocular Hypertension
Effect of Infusion Warming on Mannitol Infusion Pain in Patients With Acute Ocular Hypertension
Acute ocular hypertension is a common ophthalmic emergency that often requires rapid reduction of intraocular pressure. Intravenous mannitol is widely used for this purpose, but infusion-related pain and local venous irritation…
- Conditions
- Acute Ocular Hypertension Glaucoma, Intraocular Hypertension, Primary Angle-Closure Glaucoma
- Trial name
- NCT07495449
- Testing
- Infusion Warming Device, Routine Non-Warmed Mannitol Infusion
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong