Clinical trials: Acute Respiratory Distress Syndrom
Dyspnea, Respiratory Distress Syndrome
LUng and Cardiac Ultrasound for REspiratory Distress in ElDerly
Prospective trial to evaluate the impact on the initial therapeutic inadequacy of a management strategy for acute dyspnea in the elderly based on the use of lung and cardiac ultrasonography.
- Trial name
- LUCREED (NCT06807983)
- Testing
- diagnostic strategy based on lung and cardiac ultrasonography
- Where
- France
- Volunteers
- 504 people
- Sponsor
- University Hospital, Toulouse
Acute Respiratory Distress Syndrome, Right Ventricular Dysfunction
Detection of Right Ventricular Dysfunction by 2D Strain During Acute Respiratory Distress Syndrom (ARDS)
Acute respiratory distress syndrome (ARDS) and mechanical ventilation can lead to right ventricular dysfunction and ultimately right ventricular failure by increasing pulmonary vascular resistances and pressure load.
- Conditions
- Acute Respiratory Distress Syndrome, Right Ventricular Dysfunction, Right Heart Failure, Acute Cor Pulmonale
- Trial name
- STRAIN (NCT01757522)
- Where
- France
- Volunteers
- 47 people
- Sponsor
- University Hospital, Grenoble
Acute Respiratory Distress Syndrome
Measurement of Airway Opening Pressure (AOP) in Patients With Acute Respiratory Distress Syndrom and With or Without Covid 19.
Mechanical ventilation in ARDS requires protective ventilation and PEEP. Airway closer has to be overcome to reduce lung heterogeneity, AOP is measured globally with a ventilator PV curve without PEEP.
- Trial name
- POVA-TIE (NCT04386720)
- Where
- France
- Volunteers
- 26 people
- Sponsor
- University Hospital, Bordeaux
Acute Respiratory Distress Syndrom
Selective Lung Recruitment in Moderate to Severe ARDS : a Pilot Study
Acute respiratory distress syndrome (ARDS) is an acute condition affecting the lung after clinical aggression ( infectious process, pancreatitis, acute inflammatory event).
- Trial name
- SRIMSA (NCT06609629)
- Testing
- Selective lung recruitment
- Volunteers
- 10 people
- Sponsor
- University Hospital, Caen
ARDS, Prone Positioning
Changes in Cerebral Oxygenation During the Prone Position in Patients With Acute Respiratory Distress Syndrome
Hypoxemia may be refractory to protective ventilation during the acute respiratory distress syndrome (ARDS), justifying the use of other therapies that improved oxygenation and decreased mortality, including prone position (PP).
- Trial name
- OXYDV (NCT02415738)
- Testing
- Prone positioning
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Bretagne Atlantique
Acute Respiratory Distress Syndrome
EIT Assessment of Overdistension in ARDS Patients in Prone Position
Mechanical ventilation in ARDS requires protective ventilation with low VT and PEEP. PEEP titration can improve lung recruitment in the dependent lung but with a risk of overdistension in the non-dependant lung.
- Trial name
- DISTIE-DV (NCT06536543)
- Testing
- Acute Respiratory Distress Syndrom (ARDS) treated with Prone Position (PP) equipped with Electrical Impedance Tomography (EIT)
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bordeaux
Acute Respiratory Distress Syndrome (ARDS)
Pulmonary Overdistension Assessment With Electrical Impedance Tomography in Patients With Acute Respiratory Distress Syndrom in Prone Position.
Mechanical ventilation in COPD requires a good interaction Patient-Ventilator without asynchronies in order to reduce mortality. Dynamic hyperinflation with PEEPi is responsible for major asynchronies in COPD.
- Trial name
- Tomo-BPCO (NCT07090460)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier de la côte Basque
Acute Respiratory Distress Syndrom (SARS-Cov 2)
Evaluation of the Prognostic Value of T7 and T12 Slices on Mortality in Resuscitation Patients With ARDS Caused by SARS-COV2 Infection
Sarcopenia is a risk factor for adverse outcome in critically ill patients. Sarcopenia might be estimated from muscle surface measure on tomodensitometry.
- Trial name
- MUSCOV (NCT05594550)
- Testing
- Data collection, analysis of thoracic scans
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire Dijon