Clinical trials: Acute Wounds
Lactation
The Impact of Acute Exercise in the Heat on Breast Milk Production and Composition in Lactating Women
This clinical trial aims to determine whether heat stress alters 24-hour breast milk production and composition following an acute bout of exercise in the heat among lactating women. The main questions are: 1.
- Trial name
- NCT07036640
- Testing
- Heat exposure
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Providence College
Sepsis, Septic Shock
Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units
Background: Central Venous catheter insertion technique and indwelling time are major risk factors for CVC colonisation. Colonisation occurs through microbial migration and biofilm formation along the catheter insertion tract.
- Conditions
- Sepsis, Septic Shock, Post-cardiac Surgery, Post-Cardiorespiratory Arrest Coma
- Trial name
- NCT03270774
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Makerere University
Acute Pain, Sports Injury
Integrative Ayurveda Healing Relieves Minor Sports Injury Pain
Sports-related soft tissue injuries, such as sprains, strains, and contusions, are a common painful condition. Current treatment includes oral nonsteroidal anti-inflammatory drugs (NSAIDs), which have a high incidence of…
- Trial name
- NCT02380989
- Testing
- Ayurveda
- Where
- 3 sites in India
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Adwin Life Care
Stroke, Ischemic, Stroke Hemorrhagic
Exploring Accessible Beauty for Individuals With Upper Extremity Deficits
The purpose of this study is to investigate the accessibility of beauty products for individuals with upper extremity disabilities.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke (CVA) or TIA, Stroke, Acute
- Trial name
- NCT05945784
- Testing
- Use of Rare Beauty makeup products
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Acute Traumatic Stress Disorders, Post-Traumatic Stress Disorders
Evaluation of Stress Disorders
The purpose of this study is to examine the short-term consequences of trauma and to determine the effectiveness of the drug sertraline in preventing and treating post-traumatic stress disorder (PTSD) and acute stress disorder…
- Trial name
- NCT00050804
- Testing
- sertraline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Ankle Injuries, Ankle Sprains
Foam Rolling and Tissue Flossing of the Cuff Muscles
The hypothesis is that self-myofascial release (SMR) intervention on the cuff muscles would affect positively sprint performance and jump height, as well as, decrease Achilles tendon stiffness.
- Trial name
- NCT04367532
- Testing
- Foam rolling, Tissue flossing
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Acute Musculoskeletal Disease, Sprains
Efficacy of Lidocaine Patch in Acute Musculoskeletal Pain in the Emergency Department
This study evaluates the addition of a lidocaine patch to ibuprofen in the treatment of acute musculoskeletal pains. Half of the participants will get only ibuprofen for their pain, while other half will receive lidocaine patch…
- Conditions
- Acute Musculoskeletal Disease, Sprains, Sprains and Strains, Injuries
- Trial name
- NCT03571737
- Testing
- Ibuprofen, Lidocaine Patch 4%
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Paraplegia, Spinal, Myelomeningocele
Brain Function and White Matter Changes in Congenital, Acute and Chronic Spinal Cord Lesions
The purpose of this study is to use functional MRI (fMRI) and magnetic resonance (MR) diffusion tensor imaging (DTI) to investigate brain activation and white matter changes in patients with congenital (birth defect of the spinal…
- Trial name
- NCT01208584
- Testing
- fMRI, DTI
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Sport-related Concussion
Sub-acute Exercise Following Sport-Related Concussion
Determine the safety and efficacy of sub-maximal aerobic exercise during the subacute phase of recovery following sport-related concussion.
- Trial name
- NCT03575455
- Testing
- Exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Florida State University
Acute Radiation Syndrome
Safety and Pharmacokinetic Study of BIO 300 Capsules
This trial is designed to evaluate the safety and pharmacokinetics of BIO 300 capsules when administered orally to healthy male and female volunteers. BIO 300 is expected to be safe for use starting at 500 mg.
- Trial name
- NCT00504335
- Testing
- BIO 300 Capsules
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Humanetics Corporation
Spinal Cord Injuries, Obesity
Effects of Intermittent Hypoxia (IH) on Metabolism and Dysglycemia, in Overweight/Obese Persons SCI
The purpose of this research is to examine changes in blood glucose control and metabolism in individuals with SCI and non injured controls at rest and during exercise after five days of exposure to IH.
- Conditions
- Spinal Cord Injuries, Obesity, Insulin Resistance
- Trial name
- NCT02973438
- Testing
- Intermittent Hypoxia (IH)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Miami
Whiplash Syndrome
Investigating the Effect of an Information Video for Neck Injuries in a Emergency Department Setting
A randomized controlled trial (RCT) to investigate the effect of a information video, consisting of a multiprofessional team, on patients with acute Whiplash Associated Disorder (WAD).
- Trial name
- NCT02570659
- Testing
- Information Video
- Where
- Sweden
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Acute Pain, Fractures
Comparing Ketamine and Morphine in the Treatment of Acute Fracture Pain
Opioid pain medications such as morphine and dilaudid are commonly used in emergency departments to treat pain in patients. Physicians are familiar with the side effects of these medications; the most concerning of which is…
- Trial name
- NCT02430818
- Testing
- ketamine, morphine
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Acute Kidney Injury, Exertional Heat Illness
Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat
The goal of this clinical trial is to learn if one week of creatine monohydrate supplementation alters inflammation, markers of acute kidney injury (AKI) risk, and cognitive performance in active, young, healthy volunteers.
- Trial name
- NCT07472426
- Testing
- Creatine Monohydrate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Tibial Fractures
Pulsed Electromagnetic Field (PEMF) Stimulation for Tibia Fractures
Fractures of the tibial shaft (diaphysis) are some of the most common long bone fractures. They most frequently occur in males less than 40 years of age.
- Trial name
- NCT00127725
- Testing
- Pulsed electromagnetic field stimulation
- Where
- 5 sites in Australia
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Sydney South West Area Health Service
Stroke, Acute Stroke
Stroke and Cerebrovascular Diseases Registry
This is a single institutional registry database for the patients with stroke and cerebrovascular diseases. Stroke is the fifth leading cause of death in the United States.
- Conditions
- Stroke, Acute Stroke, Acute Brain Injury, Ischemic Stroke
- Trial name
- NCT03281590
- Where
- United States
- Volunteers
- 4,594 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Ankle Fracture
The Effect of Vitamin c on Preventing Complex Regional Pain Syndrome (CRPS Type I) Following Ankle Fracture
The use of prophylactic treatment with vitamin c may prevent complex regional pain syndrome (CRPS)
- Trial name
- CRPS (NCT01338129)
- Testing
- vitamin c
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Subarachnoid Hemorrhage, Aneurysmal
Cerebral Nitrosative/Oxidative Stress in Aneurysmal Subarachnoid Haemorrhage
Aneurysmal subarachnoid haemorrhage (SAH) carries a high morbidity and mortality, which is in part due to the development of secondary brain injury.
- Trial name
- NOX2 (NCT05686265)
- Testing
- Oxygen
- Where
- Denmark
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet