Clinical trials: Acute-graft-versus-host Disease
Low Back Pain
Effectiveness of Kinesio Tapping for the Treatment of Patients With Acute Low Back Pain: A Randomized Control Trial
The objective of the study was to determine the effectiveness of Kinesio Taping (KT) for the treatment of patients with acute low back pain.
- Trial name
- NCT05015842
- Testing
- Conventional Physical Therapy, Kinesio Tapping
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- NCS University System
Exercise, Cognition
The Effect of Acute Concurrent Exercise on Inhibitory Control: An Event-related Potential Study
The present study aimed to determine the effects of acute concurrent exercise on inhibitory control via behavioral and event-related potential approaches and to examine its potential mediational role on lactate among younger…
- Trial name
- NCT06370286
- Testing
- concurrent exercise (CE), aerobic exercise (AE)
- Where
- Taiwan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Healthy Adult
L-arginine Supplementation and Resistance Exercise
The purpose of this study was to examine the acute endothelial, cardiovascular, and performance responses to L-arginine by assessing flow-mediated dilation (FMD) and heart rate variability (HRV) both before and after resistance…
- Trial name
- NCT03827005
- Testing
- L-arginine
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- North Dakota State University
Neuropathic Pain, Spinal Cord Injuries
Pregabalin for the Treatment and Prevention of Spinal Cord Injury Neuropathic Pain
This study is a phase IV clinical trial with the objective of evaluating whether pain relief associated with pregabalin for at-level non-evoked and evoked neuropathic pain is more efficient during the early rather than late…
- Trial name
- NCT01479556
- Testing
- Pregabalin
- Where
- Spain
- Volunteers
- 82 people
- Sponsor
- Julian Taylor Green
Chronic Obstructive Pulmonary Disease, High-flow Nasal Cannula
High-flow Nasal Cannula Nebulization of Beta 2 Adrenergic Agonist During Acute Exacerbation of Chronic Obstructive Pulmonary Disease
High-flow nasal cannula is an oxygenation technique increasingly used for patients admitted for acute respiratory failure. Literature essentially concerns "de novo" acute hypoxemic failure and the interest of high-flow during…
- Trial name
- OPTINEB (NCT03449056)
- Testing
- salbutamol
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Poitiers University Hospital
Acute Lymphoblastic Leukemia
A Real-world Study of Asciminib Effectiveness in Philadelphia Positive Acute Lymphoblastic Leukemia Patients
The aim of this study was to collect existing information from the medical charts of patients enrolled in the ongoing asciminib Managed Access Program (MAP) to better understand the effectiveness and safety of asciminib when used…
- Trial name
- ASCERTAIN (NCT07644351)
- Where
- 18 sites in United States, Australia and 10 more
- Volunteers
- 37 people
- Sponsor
- Novartis Pharmaceuticals
Social Anxiety Disorder
Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder (PALISADE-3)
This U.S. Phase 3 clinical trial is designed to evaluate the efficacy, safety, and tolerability of the acute intranasal (i.n.) administration of Fasedienol Nasal Spray (fasedienol) (3.2 µg) to relieve symptoms of acute anxiety in…
- Trial name
- PALISADE-3 (NCT06358651)
- Testing
- Fasedienol Nasal Spray
- Where
- 24 sites in United States
- Volunteers
- 238 people
- Sponsor
- VistaGen Therapeutics, Inc.
COVID-19, SARS-CoV-2 Infection
Clinical Characteristics and Outcomes of Pediatric COVID-19
Rationale: The clinical manifestations of SARS-CoV-2 infection in children are poorly characterized. Preliminary findings indicate that they may be atypical.
- Conditions
- COVID-19, SARS-CoV-2 Infection, Pediatric ALL, Pneumonia, Viral
- Trial name
- PERN-COVID-19 (NCT04330261)
- Testing
- Exposure (not intervention) - SARS-CoV-2 infection
- Where
- Canada
- Volunteers
- 10,610 people
- Sponsor
- University of Calgary
Acute Stroke
EEG Motor Movement and Imagery Dataset for Stroke
The investigators collect and analyze the alpha and beta wave of EEG activity at the motor cortices of the participants, When the motor task is being performed.
- Trial name
- NCT05499442
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xuanwu Hospital, Beijing
Diarrhea
Zinc Dosing Trial - Does Dose Reduction Reduce Side Effects But Retain Efficacy in Diarrhoea Management
Diarrhoea continues to be a major cause of child deaths. Current treatment of acute watery diarrhoea includes oral rehydration solution (ORS), zinc and continued feeding.
- Trial name
- ZTDT (NCT03078842)
- Testing
- Zinc tablets, 20 mg per day, Zinc tablets, 10 mg per day, Zinc tablets, 5 mg per day
- Where
- 2 sites in India, Tanzania
- Volunteers
- 4,500 people
- Sponsor
- Ayesha De Costa
Low Back Pain, Mechanical
The Biomechanical Effects of Manual Therapy - A Feasibility Study
The aim of this study is to determine the feasibility of conducting a full-scale trial to explore if there is a change in intervertebral movement following a course of manual therapy in patients with acute non-specific low back…
- Trial name
- NCT04155970
- Testing
- Manual therapy, Evidence-informed home management booklet
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Bournemouth University
Leukemia
CMA-676 in Treating Older Patients With Acute Myeloid Leukemia in First Relapse
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of CMA-676 in treating older patients who have acute…
- Trial name
- NCT00003673
- Testing
- chemotherapy, gemtuzumab ozogamicin
- Where
- 10 sites in United States
- Volunteers
- 55 people
- Sponsor
- Pfizer
Acute Spinal Cord Injury (SCI), Acute Spinal Cord Injury of Traumatic Origin (tSCI)
Safety of Transcutaneous Electrical Stimulation Potentiating Recovery in Acute Spinal Cord Injury Syndromes
The goal of this study is to test whether electrical stimulation from the skin surface starting 3 days after spinal cord injury (SCI) is safe and may help patients recover their movement.
- Trial name
- STEP-RAISE (NCT07090473)
- Testing
- transcutaneous spinal cord stimulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Myelodysplastic Syndromes
Collection of Blood, Bone Marrow, Skin, Saliva, and Stool Samples From Healthy Volunteers Used for Comparative Analysis of Myeloid Malignancies
Background: Myelodysplastic syndromes (MDS) are disorders of blood stem cells that can develop into blood cancers. Treatment options are limited. To find better treatments, researchers need to better understand how MDS develops.
- Trial name
- NCT05588154
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Acute Lung Injury
Acute Lung Injury After Allogeneic Transplantation - Diagnosis and Early Treatment
Acute lung injury (ALI) is an early complication after allogeneic transplantation causing significant mortality and morbidity. Little is known on early markers and treatment of this complication.
- Trial name
- NCT00852605
- Testing
- Intermittent Non-Invasive Ventilation
- Volunteers
- 86 people
- Sponsor
- Technische Universität Dresden
Cancer Survivors, Rehabilitation
Multidisciplinary Rehabilitation of Children and Adolescents After Acute Cancer Treatment
Recent numbers display a 85% survival-rate in children after a very harmful disease such as cancer. However, the survivors still experience mild to severe side effects of the primary disease or treatment.
- Conditions
- Cancer Survivors, Rehabilitation, Exercise Therapy
- Trial name
- NCT05154305
- Testing
- multidisciplinary intervention
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Hospital, Ghent
Asthma, COPD
Exhaled Breath Metabolomic Biomarkers in the Acutely Breathless Patient
An acute study carried out across three acute admissions units within Leicestershire. The study is aimed at discovery and validation of volatile organic compounds (VOCs) in exhaled breath.
- Conditions
- Asthma, COPD, Heart Failure, Community-acquired Pneumonia
- Trial name
- EMBER (NCT03672994)
- Where
- United Kingdom
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Muscle Contractile Properties, Resistance Exercise
Foot Progression Angle and Leg Press: Vastus Medialis Contractile Responses
This study examined the interaction between rotational foot positioning during leg press and individuals' habitual foot progression angle (FPA) phenotype on the acute contractile response of the vastus medialis muscle
- Conditions
- Muscle Contractile Properties, Resistance Exercise, Foot Progression Angle
- Trial name
- NCT07546851
- Testing
- Congruent Foot Position Leg Press, Incongruent Foot Position Leg Press
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Giresun University
Hypopituitarism
Acute Neuroendocrine Response to Intravenous Infusion of Diclofenac Sodium
The effects of acute administration of non-steroidal anti-inflammatory drugs (NSAIDs) on the neuroendocrine regulation of hydro-electrolytic metabolism are not precisely known to date.
- Trial name
- NCT05188131
- Testing
- Intravenous Infusion of Diclofenac Sodium
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- A.O.U. Città della Salute e della Scienza
Acute Kidney Injury, Renal Injury
Pediatric Acute Kidney Injury (AKI) Retrospective, Real-Time and Repository Research
This proposal will incorporate statistical models developed by the investigators to predict risk for acute kidney injury into our electronic medical record system, enabling an alert to notify providers of the risk status.
- Conditions
- Acute Kidney Injury, Renal Injury, Kidney Disease
- Trial name
- PAR4 (NCT02660931)
- Testing
- AKI Risk Notification
- Where
- United States
- Volunteers
- 12,108 people
- Sponsor
- Vanderbilt University Medical Center
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