Clinical trials: Adaptation
Broken Down Molars, IPS-emmax Crowns
Evaluation of a New Design of Crowns in the Posterior Teeth
Background: no randomized controlled trial has tried to compare treatment outcomes between the IPS.emmax endocrowns and the IPS.emmax conventional crowns .
- Trial name
- NCT02110550
- Testing
- IPS.emmax endocrown
- Where
- 2 sites in Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Posttraumatic Stress Disorder, Substance Use Disorders
Adaptation of Written Exposure Therapy in Substance Treatment
The purpose of this pilot non-randomized, uncontrolled clinical trial is to test the feasibility and efficacy of written exposure therapy (WET) for posttraumatic stress disorder (PTSD) as adapted for use within the context of…
- Trial name
- WEST (NCT07108608)
- Testing
- Written Exposure Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Potomac Health Foundations
Secondary Hypothyroidism, Hypopituitarism
Phase 4 Study in Secondary Hypothyroidism: Body Weight Adapted Thyroxin Treatment and Triiodothyronine Supplementation
The purpose of this study is to determine whether a body weight adjusted dose of thyroxin is superior to treatment guided by laboratory results of thyroxin hormones in patients with central hypothyroidism.
- Conditions
- Secondary Hypothyroidism, Hypopituitarism, Hyperlipidemias
- Trial name
- NCT00360074
- Testing
- Thyroxin, Triiodothyronine
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- University Hospital Freiburg
Peripheral Arterial Disease
Adapted Physical Activity in Patients With Lower Limb Peripheral Arterial Disease
The prevalence of peripheral arterial disease is 12.2% in France. Intermittent claudication is the most common symtom of this disease. During physical exercise, such as walking, blood oxygen (O2) requirements increase.
- Trial name
- ACTIV'AO (NCT04800276)
- Testing
- muscle strengthening targeted on ischemic areas, global muscle strenghtening
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier le Mans
Endometrial Cancer, Cardiovascular Diseases
Strive Cardio for Endometrial Cancer Survivors
STRIVE Cardio is a 12-week exercise intervention study with the goal to improve functional fitness and cardiovascular health for women who have completed treatment for non-metastatic endometrial cancer within the last five years…
- Trial name
- NCT06534008
- Testing
- 12-week home-based exercise intervention
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Jess S. Gorzelitz
Muscle Performance, Resistance Training
Effects of Weekly Set Volume on Muscle Adaptation
The progressive loss of strength and muscle mass is a natural aging process, with direct implications for functional capacity. Resistance training (RT) is considered the main intervention to counteract this decline.
- Trial name
- NCT07379385
- Testing
- Low volume (LV), Moderate Volume (MV), High Volume (HV)
- Where
- Brazil
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Universidade Norte do Paraná
Spatial Neglect
Engaging Mobile Prism Adaptation Treatment at Home
Spatial neglect is a common disorder after stroke which leads to problems with noticing or responding to information from the left side of the body or space.
- Trial name
- EMPATH (NCT05595668)
- Testing
- Prism Adaptation - 15-degree prism goggles, Prism Adaptation - 5-degree prism goggles
- Where
- 4 sites in Canada
- Volunteers
- 80 people
- Sponsor
- Nova Scotia Health Authority
Obesity
ADAPT Study: Assessing Diet, Appetite and Physiology Throughout Weight Loss Study)
Behavioral weight loss programs for obesity can result in weight loss and health benefits. However, behavioral weight loss often stops despite efforts to continue losing weight, this can be called an involuntarily weight loss…
- Trial name
- NCT06174389
- Testing
- Behavioral Weight Loss Program
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Washington
Caregiver Burden of People With Dementia
AIM 3 Focused Adaptation of a Mobile Caregiver Intervention for Dementia Caregivers
The goal of this clinical trial is to evaluate usability, feasibility and preliminary efficacy of a mobile telehealth supported behavioral intervention for caregivers of persons with dementia who identify as Hispanic.
- Trial name
- FAMILIA (NCT07792889)
- Testing
- Brain CareNotes Latino, Dementia Care app
- Volunteers
- 60 people
- Sponsor
- Indiana University
Geriatric Care
Prevention of Pain Induced During Bed Bath in Ehpad
Residents of long-term care facilities are subjected to procedures and treatments that may be painful. The prevalence is 90% among older adults living in institutions.
- Trial name
- TODOMOB (NCT07691385)
- Testing
- Standard personal hygiene, Adapted toilet
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Hôpital NOVO
Stress Urinary Incontinence
Abdominal-Kegel Exercise and the Effect of Telemedicine in Stress Urinary Incontinence
Urinary incontinence is a very common health problem that reduces the quality of life mostly in women. Behavioral therapy (lifestyle changes, abdominal-Kegel exercises) is recommended as the first choice in the treatment of the…
- Trial name
- NCT06189443
- Testing
- Group administered to individual telemedicine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Chronic Obstructive Pulmonary Disease (COPD)
Oral β-Alanine Supplementation in Patients With COPD
Preliminary evidence suggest that patients with chronic obstructive pulmonary disease (COPD) suffer from lower-limb muscle dysfunction.
- Trial name
- BACOPD (NCT02770417)
- Testing
- beta-alanine, control
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Lumbar Spine Adaptation
Adaptation of Lumbar Spine to a Mattress: a MRI Evaluation.
People spend almost a third of their life sleeping and understanding how the spine can adapt to a mattress is essential for promoting people's health.
- Trial name
- Mattress&Spine (NCT04638374)
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Overweight (BMI > 25), Males and Females
IMPACT: Immune and Musculoskeletal Physiological Adaptations to Combined Exercise Training & Nutrition
The purpose of this study is to determine whether 12 weeks of exercise training combined with dairy consumption influences inflammation and immune responses in adults with overweight, compared to exercise training alone.
- Trial name
- NCT07513987
- Testing
- Milk, Greek Yogurt, Exercise training
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- York University
Sport, Supplements
The Effect of β-hydroxy-β-methylbutyrate Supplementation on Physical Capacity and Body Composition in Trained Athletes
The purpose of this study was to verify the effect of 12-week with β-hydroxy-β-methylbutyrate (HMB) and a placebo (PLA) supplementation on body composition, anaerobic and aerobic capacity, as well as concentrations of the…
- Conditions
- Sport, Supplements, Supplementation
- Trial name
- NCT03028649
- Where
- Poland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Bereavement
Cultural Adaptation of a Self-help App for Grieving Syrian Refugees in Switzerland
The goal of this pilot RCT is to investigate the acceptability and feasibility of an unguided culturally adapted self-help app for grieving Syrian refugees in Switzerland.
- Trial name
- NCT06246708
- Testing
- Self-help app with information for grieving Syrian Refugees, Wait-list
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Mixed Reality, Asymptomatic
Validity and Reliability of a Mixed Reality-Based 6-Minute Walk Test
The 6-Minute Walk Test (6MWT) is a widely used field test for assessing functional exercise capacity, walking endurance, and submaximal performance related to activities of daily living.
- Trial name
- NCT07601009
- Testing
- Mixed Reality-Based 6-Minute Walk Test Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Obesity, Overweight (BMI > 25)
Impact of Protein Supplementation and Resistance Training on Body Composition, Functional Parameters, Metabolic Adaptation, and Nitrogen Balance in Adults Aged 45 Years and Older With Overweight or Obesity Receiving Incretin-based Medications
This study aim to evaluate the effects of protein supplements and resistance training on body composition, functional parameters, metabolic adaptation, and nitrogen balance in adults (aged ≥45 years) with overweight/obesity…
- Conditions
- Obesity, Overweight (BMI > 25), Weight Loss
- Trial name
- PRIME (NCT06950684)
- Testing
- Whey Protein Supplement, Resistance Training Program
- Volunteers
- 180 people
- Sponsor
- Assuta Medical Center
Overweight (BMI > 25), Obesity
Redox Status and Exercise Training-induced Adaptations
Excess fat accumulation is a key feature of overweight and obesity that is mainly driven by nutrient overload and insufficient physical activity.
- Trial name
- NCT07196852
- Testing
- N Acetyl L Cysteine
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Exercise Training
Exercise-Induced Metabolic Compensation; a Physiological Adaptive Response to Exercise Training
The primary aim of this proposal is to identify changes in the volume of highly metabolic organs (liver, kidneys, and brain) that occur as a physiological adaptation to exercise training and lower the resting energy expenditure.
- Trial name
- NCT04460040
- Testing
- Exercise training
- Where
- Israel
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University