Clinical trials: Adaptation
Iodine Deficiency
The Next Step Towards the Elimination of Iodine Deficiency and Preventable Iodine-related Disorders in Europe
In the EUthyroid2 intervention, measures are being developed and implemented in educational settings across the UK, Germany, Slovenia, the Republic of Cyprus, Bangladesh, and Pakistan to effectively raise awareness of the risks…
- Trial name
- EUthyroid2 (NCT06801691)
- Testing
- Experimental: Intervention group
- Where
- 6 sites in Bangladesh, Cyprus and 4 more
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- EUthyroid
Focus of Study: Tailored Implementation
PIECES - Towards Large-Scale Adaptation and Tailored Implementation of Primary Cancer Prevention Programs
The PIECES project aims to evaluate the Primary Cancer Prevention Implementation Toolkit (PCP-IT), an online implementation support toolkit that aids implementation teams in improving the implementation of primary cancer…
- Trial name
- PIECES (NCT06718322)
- Testing
- Primary Cancer Prevention Implementation Toolkit (PCP-IT)
- Where
- 11 sites in Albania, Australia and 7 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hidde van der Ploeg
Breast Cancer, Hereditary Breast Cancer
Testing a Culturally Adapted Telephone Genetic Counseling Intervention
Participating in genetic cancer risk assessments (GCRA) for hereditary breast and ovarian cancer (HBOC) can inform treatment and risk management decisions and improve breast cancer outcomes.
- Trial name
- NCT03959267
- Testing
- Telephone Genetic Counseling
- Where
- 4 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Eating Habit, Healthy Diet
Study to Evaluate the Efficacy of YOUR SUPER Detox Bundle to Improve Perceived Well Being and Promote Adaptation of Healthy Dietary Choices
This is an open-label observational single-group clinical trial to study the efficacy of a commercial superfood blend and its effect on markers of well-being and improvement of long-term healthy eating habits.
- Trial name
- NCT05303207
- Testing
- YOUR SUPER Detox Bundle
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Your Super, INC.
Electroconvulsive Therapy (ECT), Electroconvulsive Therapy Cognitive Assessment (ECCA)
ECCA's Turkish Validity and Reliability Study and Comparison With Other Cognitive Assessment Tests
Electroconvulsive therapy (ECT) is one of the oldest biological treatment methods used in psychiatry, based on inducing widespread seizures in the brain with externally applied controlled electrical currents.
- Conditions
- Electroconvulsive Therapy (ECT), Electroconvulsive Therapy Cognitive Assessment (ECCA), Montreal Cognitive Assessment (MoCA), Turkish Adaptation
- Trial name
- NCT07527234
- Testing
- ElectroConvulsive Therapy Cognitive Assessment (ECCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Pamukkale University
Parkinson Disease
Tele-Rehabilitation in Parkinson's Disease
Parkinson's disease (PD) is a neurodegenerative disease that occurs with the effect of dopaminergic pathways in the substantia nigra and causes a progressive decrease in motor functions.
- Trial name
- NCT04982887
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people
- Sponsor
- Hacettepe University
Infant Development
The Polish Version of the Alberta Infant Motor Scale: Cultural Adaptation and Validation
The aim of the study was to derive a Polish version of the AIMS through its cultural adaptation and validation. This process was based on an analysis of intra- and interrater reliability, as well as concurrent validity, using…
- Trial name
- NCT05264064
- Testing
- The motor assessment to establish validation of the Polish version of the AIMS
- Where
- Poland
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Cerebral Palsy
Activities-based Locomotor Training Program Versus Traditional Physical Therapy in Children With Cerebral Palsy
The purpose of this study is to investigate the impact of an intensive activities-based locomotor training program as compared to traditional physical therapy on activity, participation, and central and peripheral…
- Trial name
- NCT06352814
- Testing
- Activities-based locomotor training (physical therapy)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Baylor University
Chronic Right Supratensorial Stroke Patients
Prismatic Adaptation for Rehabilitation of Postural Imbalance After Stroke
Postural imbalance after stroke leads to limitations of activity and a worse autonomy. The postural imbalance is increased in right supratensorial stroke (RSS) compared to left supratensorial stroke.
- Trial name
- PEQUIE (NCT03154138)
- Testing
- The prismatic adaptation (PA)
- Where
- 3 sites in France
- Volunteers
- 28 people
- Sponsor
- Hospices Civils de Lyon
Ischemic Stroke, Acute Stroke
Continuous Dual Aspiration Technique With Zoom System for Stroke
This study is designed to evaluate the effectiveness, safety and clinical performance of ADAPT 2.0, first-line aspiration neurothrombectomy with Zoom System with Continuous Dual Aspiration Technique (CDAT).
- Trial name
- ADAPT 2 0 (NCT07491952)
- Testing
- Zoom System
- Where
- 25 sites in United States
- Volunteers
- 750 people
- Sponsor
- Imperative Care, Inc.
Solid Tumor, Solid Tumor, Adult
Psychotherapy Intervention for Latinos With Advanced Cancer
The purpose of this study is to adapt a counseling intervention called Meaning Centered Psychotherapy to make it culturally relevant for Latinos. Cancer affects patients and their loved ones.
- Conditions
- Solid Tumor, Solid Tumor, Adult, Solid Tumor, Unspecified, Adult
- Trial name
- NCT04015609
- Testing
- Meaning Centered Psychotherapy for Latinos, Functional Assessment of Cancer Therapy - Spiritual Well-Being Scale, Meaning Centered Psychotherapy for Latinos for Waitlist Control Patients
- Where
- 4 sites in United States, Puerto Rico
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Active Aging Individuals Aged 65 and Over, Aging
Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables
The goal of this experimental multicentric intervention study is to validate, in Italian, the dynamic Neurocognitive Adaptation (dNA) Scale, which has already been validated in English, among a healthy elderly population (aged 65…
- Conditions
- Active Aging Individuals Aged 65 and Over, Aging, Mild Cognitive Impairment (MCI), Dementia
- Trial name
- NCT07533084
- Where
- 8 sites in Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Hematopoietic Stem Cell Transplant
Effects of Compassion Training to Patients Undergoing HSCT on Biological and Psychosocial Parameters
The hematopoietic stem cell transplant (HSCT) experience is emotionally and physically stressful for cancer patients who undergo this procedure.
- Trial name
- NCT03737084
- Testing
- CBCT Intervention
- Where
- 2 sites in Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Physical Activity
Small-sided Ball Game Training and Protein Intake in Older Adults
The effect of small-sided team sport training and protein intake on muscle mass, physical function, and adaptations important for health in untrained older adults was examined.
- Trial name
- NCT03120143
- Testing
- Small-sided ball game training with high protein intake, Small-sided ball game training with low protein intake
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Adaptation of Different Types of Clear Aligners
Randomized In-Vivo Comparison of 3D-Printed and Thermoformed Clear Aligners: A Multi-Subject, Time-Dependent Analysis of Adaptation and Trueness
This prospective clinical study aims to evaluate and compare the in vivo adaptation and trueness of clear aligners fabricated using thermoforming and direct three-dimensional (3D) printing technologies.
- Trial name
- NCT07639515
- Testing
- Device: Invisalign Passive Clear Aligner, Spark Passive aligners, Zendura passive aligner
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
PCOS (Polycystic Ovary Syndrome)
Symptoms of Polycystic Ovarian Syndrome Ameliorated by Keto-Adaptation Pilot
The SPARK- Pilot study (Symptoms of PCOS Ameliorated by Responses to Keto-adaptation) is a 12-week clinical trial at The Ohio State University designed to explore how different ways of achieving ketosis may improve reproductive…
- Trial name
- (SPARK-Pilot) (NCT07227363)
- Testing
- Ketogenic diet, Exogenous Ketone Supplement
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ohio State University
Electrical Stimulation
Angles of Knee and Hip Joints for Optimization of Neuromuscular Electrical Stimulation of the Quadriceps Femoris Muscle
Introduction: The muscle contractile effectiveness is influenced by the neural activation of the motor units, as well as its architecture and the elasticity of the myotendinous junction.
- Trial name
- NCT03822221
- Testing
- MVIC and NMES with hip at 85º and knee at 20º, MVIC and NMES with hip at 85º and knee at 60º, MVIC and NMES with hip at 0º and knee at 20º
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Participation, Patient, Child, Only
Turkish Version of the "Children's Assessment of Participation With Hands Scale
To the best of our knowledge, there is no Turkish validity and reliability scale that can reveal children's hand involvement. In the study in which the CAP-H was developed, it was stated that this scale could be used in…
- Trial name
- NCT04904848
- Testing
- Survey evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 182 people
- Sponsor
- Pamukkale University
Cardiovascular Diseases
Comparing Multicomponent and Isometric Multicomponent Training: Impact on Fitness, Health, and Life Quality in Heart Patients
The goal of this clinical trial is to evaluate if a multicomponent training program (MCT), including aerobic and resistance exercises, or an isometric multicomponent training program (IMCT) can improve physiological, physical…
- Trial name
- NCT06819098
- Testing
- Multicomponent Training Protocol, Isometric Multicomponent Training
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Bari Aldo Moro
Diabetes Mellitus, Type 2
Translation, Cultural Adaptation and Validation of the Creole Versions of the EQ-5D and the SF-36 Questionnaires in Patients With Type II Diabetes in Reunion Island, Martinique and Guadeloupe
The evaluation of quality of life in health is particularly important for measuring the impact of the chronic diseases. The scales of measure constitute the main measurement tool in clinical trials because of their psychometrics…
- Trial name
- CreoQol (NCT02898493)
- Where
- France
- Volunteers
- 750 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion