Clinical trials: Adaptive Radiotherapy
Cancer
Magnetic Resonance-Guided Adaptive Radiotherapy (MRgART) Using an Integrated Magnetic Resonance Linear Accelerator (MRL)
This study is being done to help further understand how MR-guided adaptive RT in conjunction with the Integrated Magnetic Resonance Linear Accelerator (MRL) can improve patient outcomes.
- Trial name
- MRL1 (NCT04135794)
- Where
- Canada
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Lung Cancer, Lung Tumor
Study of LUNG Stereotactic Adaptive Ablative Radiotherapy
The proposed study expands on the principles of SBRT (Stereotactic Body Radiation Therapy) and SABR (Stereotactic Ablative Radiotherapy) for centrally located NSCLC (Non-Small Cell Lung Cancer) to further optimize outcomes in…
- Trial name
- LUNG STAAR (NCT04917224)
- Testing
- Stereotactic Adaptive Ablative Radiotherapy at 50 Gy (Gray), Stereotactic Adaptive Ablative Radiotherapy at 60 Gy (Gray)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baptist Health South Florida
Carcinoma, Glioblastoma
MRinRT: Swansea University and SWWCC Collaboration Study.
The aim of this study is to learn whether using MRI (magnetic resonance imaging) scans to plan radiotherapy is better than using CT (computed tomography) scans alone.
- Conditions
- Carcinoma, Glioblastoma, Radiotherapy, MRI
- Trial name
- MRinRT (NCT07365124)
- Testing
- MRI
- Where
- United Kingdom
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Swansea Bay University Health Board
Prostate Cancer
MR-based Hypofractionated Adaptive IGRT of Prostate Cancer (M-base HyPro 2.0)
Single-centre single-armed, non-randomized interventional phase II-study of hypofractionated image-guided radiotherapy "IGRT" with weekly magnetic resonance imagings "MRI" for personalized adaptation of the treatment plan…
- Trial name
- Mbase_HyPro (NCT03880851)
- Testing
- Plan adaptation of Radiation Treatment in case of anatomical changes
- Where
- Germany
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Radiation Protection
Enhancement and Restoring of Low Dose Abdominal CT Images
Through the rapid growth of multislice Computer Tomography (CT) imaging, radiation protection has become a major issue in the radiological community.
- Trial name
- NCT01059032
- Testing
- Using a 3 dimentional post processing filter
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Lars Borgen
Cervical Neoplasm, Adaptive Radiotherapy
Moderately Hypofractionated Adaptive Radiotherapy for Cervical Cancer
External radiation given in 25 fractions or so together with weekly chemotherapy and followed by 5 or 6 fractions of brachytherapy is the standard of care for patients with locally advanced cervical cancer.
- Conditions
- Cervical Neoplasm, Adaptive Radiotherapy, Radiotherapy; Adverse Effect
- Trial name
- NCT05994300
- Testing
- Moderately hypofractionated adaptive radiotherapy (ART)+ High-dose rate (HDR) Brachytherapy
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Bladder Cancer
Evaluation of Ultrasound Probe for Use in Bladder Radiotherapy
Muscle-invasive bladder cancer affects over 3,000 new patients in the UK each year and radiotherapy comprises a key part of the treatment pathway for many of them.
- Trial name
- NCT01698359
- Where
- United Kingdom
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Head and Neck Cancer
MR-Linac for Head and Neck SBRT
This study will evaluate the feasibility and safety of using MR-guided adaptive Head and Neck stereotactic radiotherapy (SBRT) at each fraction on the 1.5T MR-Linac.
- Trial name
- NCT04809792
- Testing
- SBRT on the MR-Linac
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Recurrent Prostate Cancer After Surgery
This Study is Evaluating a New Radiation Treatment Technique for Patients Who Have Had Prostate Cancer, Undergone Surgery for Cancer, and Then Have Evidence That Their Prostate Cancer Has Returned.
There is significant, proven use of radiation for recurrent prostate cancer after surgical resection. This treatment typically is delivered over seven and a half weeks of daily treatments, presenting a burden to patients and the…
- Trial name
- DASBRT-RPC (NCT05946824)
- Testing
- Daily-adaptive Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Skin Cancer
EUREKA: Evaluating Ultraviolet Radiation Exposure in Kids for Adaptive Intervention
This project will pilot a Just In Time Adaptive Intervention (JITAI) approach to providing feedback on child UVR exposure to children and their parents, with the ultimate goal of improving child use of sun protection strategies…
- Trial name
- EUREKA (NCT07204704)
- Testing
- EUREKA Intervention
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Utah