Clinical trials: Addiction
Nicotine Dependence, Nicotine Addiction
A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults
Almost one in ten young adults report current e-cigarette use, putting them at risk of developing nicotine addiction and long-term health effects of exposure to inhaled toxicants.
- Conditions
- Nicotine Dependence, Nicotine Addiction, Nicotine Use Disorder, Nicotine Vaping
- Trial name
- NCT05897242
- Testing
- Smartphone app, Text Message, Survey Administration
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Motivational Interview, Addiction
The Effect of Motivational Interviews on the Digital Game Addiction Levels of Nursing Students
The aim of this study is to reveal the effect of motivational interviewing based on change stages on digital game addiction. This study will be conducted with a total of 72 individuals assigned by a randomization site from all…
- Trial name
- NCT05457777
- Testing
- Motivational interview in digital game addiction
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Fidan Balkaya
Drug Addiction, Smoking Cessation
Examining the Effect of the Nicotine Patch in Male and Female Smokers - 3
Treatment studies have demonstrated that current smoking cessation techniques are less effective for women. The purpose of this study is to determine the role that gender plays in the effectiveness of nicotine replacement…
- Trial name
- NCT00390559
- Testing
- nicotine transdermal system, Nicotine containing cigarette
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Normal Physiology
Development Of Neuroimaging Methods To Assess The Neurobiology Of Addiction
Background: Abusing alcohol, drugs, and other substances can cause serious health problems. These substances also can affect brain function.
- Trial name
- NCT02535702
- Testing
- In vivo MRS, fMRI, EEG/EOG
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Cervicogenic Headache, Sleep Disturbance
Effect of Isometric Neck Exercises on Cervicogenic Headache Symptoms, Cortisol and BDNF Levels Among Smart Phone Users
Cervicogenic headache (CGH) is a secondary headache type caused due to refereed pain arising from the cervical spine in the forehead, sometimes in temporal region.
- Conditions
- Cervicogenic Headache, Sleep Disturbance, Stress
- Trial name
- NCT07354776
- Testing
- Isometric Neck Exercise Program, Usual Care
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Rheumatoid Arthritis (RA), Ankylosing Spondylitis (AS)
An Investigation of the Effect of Smartphone Usage Levels on Cervical Posture, Tongue Pressure, Balance, and Neck Disability in Individuals With Rheumatoid Arthritis and Ankylosing Spondylitis
The purpose of this cross-sectional and comparative study is to investigate the impact of smartphone addiction on the cervical posture, musculoskeletal system, balance, and tongue pressure in individuals diagnosed with Rheumatoid…
- Conditions
- Rheumatoid Arthritis (RA), Ankylosing Spondylitis (AS), Forward Head Posture
- Trial name
- NCT07627542
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Merve Şahin
Tobacco Use Disorder
Impact of Cigar Flavor in Dual Users
The purpose of this study is to understand addiction to filtered cigars (FCs) compared to cigarettes in young adults, ages 21-34, who smoke both cigarettes and cigars.
- Trial name
- NCT04487470
- Testing
- Flavored filtered cigars, Unflavored filtered cigars
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- UConn Health
Heroin Addiction, Relapse
PET/MRI Study on the Neurological Mechanism of rTMS Treatment for Heroin Addiction
Heroin addiction is a serious problem and the relapse rate of existing treatment methods is extremely high. Recently, international journals such as Science reported that repetitive transcranial magnetic stimulation (rTMS) can…
- Trial name
- NCT04086459
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Alcohol Use Disorder (AUD)
The Zonisamide and Reinforcement for Reducing Alcohol Use (ZARRA) Study
A phase II randomized, double-blind, placebo-controlled clinical trial (RCT) to evaluate the ability of zonisamide (ZON) to decrease alcohol use among treatment-seeking adults with an alcohol use disorder (AUD).
- Trial name
- NCT05134857
- Testing
- Zonisamide
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Washington State University
Substance Use Disorders
Smartphone Addiction Recovery Coach for Young Adults (SARC-YA) Experiment
At discharge from outpatient treatment, researchers will recruit 300 young adults and randomly assign them to recovery support as usual control condition or the Smartphone Addiction Recovery Coach for Young Adults (SARC-YA)…
- Trial name
- SARC-YA (NCT03301012)
- Testing
- Recovery support as usual, Smartphone assisted relapse prevention
- Where
- 2 sites in United States
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Chestnut Health Systems
Acute Exercise and Addictive Behavior
Effect of Exercise on Chocolate Addiction
The study will use stress inducing tasks to determine if there are significant improvements in mood, chocolate cravings, and attentional bias to chocolate in overweight/obese chocolate abusers following rest and a bout of high…
- Trial name
- NCT03356509
- Testing
- Exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Miami
Mental Health, Addictions
Better Access to and Integration of Mental Health and Addiction Services Through Navigation: A Mixed-Methods Adaptive Pragmatic Clinical Trial
The Family Navigation Project (FNP), a youth and family mental health and addictions (MHA) navigation service that currently operates in the Greater Toronto Area (GTA), is expanding to northern Ontario by setting up a new site in…
- Conditions
- Mental Health, Addictions, Patient Navigation, Health Services
- Trial name
- BEAM (NCT07707492)
- Testing
- Family Navigation Project
- Where
- 2 sites in Canada
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Adolescence, Digital Addiction
The Effect of Addiction Management Training on Digital Addiction and Psychological Resilience in Secondary School Students: A Randomised Controlled Trial
This study aims to examine the effect of an addiction management programme, applied to sixth-grade middle school students at high risk of digital addiction on digital addiction and psychological resilience.
- Trial name
- NCT06468839
- Testing
- addiction management training
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara University
Technology Addiction, Adolescent Health
The Effect of Technology Addiction on Physical Activity and Attention Levels in Adolescents
This study aimed to investigate the relationship between technology addiction and physical activity and attention levels in adolescents.
- Conditions
- Technology Addiction, Adolescent Health, Attendance Level
- Trial name
- NCT07532720
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
Cocaine Dependence
Investigation of Cocaine Addiction Using mGluR5 PET and fMRI
The proposed research program will investigate the changes in brain chemistry and circuitry that 're-wire' the brain during chronic cocaine use, promote relapse, and complicate treatment efforts.
- Trial name
- NCT03471182
- Testing
- Psychiatric and Cognitive Testing, Cocaine Self-adminstration, Positron Emission Tomography
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Yale University
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Addiction Chemical, Use, Substance
Substance Use Disorder in Chemsex Practice
The main aim of this descriptive cross-sectional study is to assess the prevalence of chemsex substance use disorder among chemsexers via an online self-questionnaire.
- Trial name
- TU CHEMSEX (NCT06476873)
- Testing
- Online self-questionnaire.
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Community Reinforcement And Family Training, Family Health
Phase II: Scalable Digital Delivery of CRAFT Training for Professionals to Maximize Treatment Rates of OUD in Families
The goal of this project is to demonstrate digital training efficacy at scale and commercial readiness. This pilot project will advance piloted digital training programs for CRAFT and maximize scalability.
- Conditions
- Community Reinforcement And Family Training, Family Health, Substance-Related Disorders
- Trial name
- NCT06685003
- Testing
- Digital Tutorial overview, Digital Tutorial plus training Materials, Digital Tutorial plus training Materials plus feedback and Coaching
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- We The Village, Inc.
Alcohol Abuse, Arteriosclerosis
Clinical Study of Ligustrazine in Treating Alcohol Addiction
Alcohol consumption is one of the most important risk factors for chronic non-communicable diseases in the population, and it is also the main cause of death from cancer, cardiovascular disease and lung disease, causing serious…
- Trial name
- NCT05942352
- Testing
- Ligustrazine by intravenously administration, Ligustrazine by mouth
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shenzhen Kangning Hospital
Alcohol Dependence, in Remission, Addiction, Alcohol
Does Treatment With GLP-1 Reduce Alcohol Intake in Patients With Alcohol Dependence?
The study is a double-blinded, randomized, placebo-controlled, 26-weeks clinical trial. The objective of the trial is to investigate the effects of the GLP-1 receptor agonist Bydureon® (exenatide) vs.
- Trial name
- EXALT (NCT03232112)
- Testing
- Exenatide 2 MG Injection, BD PosiFlush (saline)
- Where
- Denmark
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Anders Fink-Jensen, MD, DMSci