Clinical trials: Addiction
Opioid-Related Disorders, Drug Addiction
Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study
This is a sub-study of NIDA CTN Protocol 0080: Medication Treatment for Opioid Use Disorder in Expectant Mothers (MOMs; Unique protocol ID: 2019-0429-1).
- Conditions
- Opioid-Related Disorders, Drug Addiction, Pregnancy Related, Substance Abuse
- Trial name
- MOMs-INO (NCT03911739)
- Testing
- Buprenorphine Injection, Buprenorphine Sublingual Product
- Where
- 10 sites in United States
- Volunteers
- 71 people
- Sponsor
- T. John Winhusen, PhD
Implementation Science
Implementation of Two Transdiagnostic Interventions Based on Emotional Regulation (DBT and UP) for Alcohol Addiction
The aim of this study is to evaluate the dissemination and implementation process of two transdiagnostic psychological interventions (Dialectical Behavioral Therapy for Substance Use Disorders-DBT-SUD and Unified Protocol-UP) to…
- Trial name
- NCT06366100
- Testing
- Dialectical Behavior Therapy for Substance Use Disorder (DBT-SUD), Unified Protocol (UP)
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Smoking, Smoking Behaviors
Smoking Prevention Program in Poland
Smoking Prevention Program is a pilot exploratory study with a standardized curriculum based on the Tobacco Prevention Toolkit from Stanford University and translated into Polish by the members of Students Scientific Association…
- Conditions
- Smoking, Smoking Behaviors, Smoking (Tobacco) Addiction, E-cigarette Use
- Trial name
- NCT05488743
- Testing
- educational intervention
- Where
- Poland
- Volunteers
- 180 people
- Sponsor
- Wroclaw Medical University
Opiod Use Disorder
Safety, Tolerability, and Pharmacokinetics of Naltrexone Implant (DLP-160)
This is an Open-Label Study in Healthy Volunteers to Evaluate the Safety, Tolerability, and Pharmacokinetics of Switching from Oral Naltrexone HCL to DLP-160 (Naltrexone implant) to Intramuscular Vivitrol®
- Trial name
- NCT05304364
- Testing
- Combination Product: Naltrexone
- Where
- Australia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Delpor, Inc.
Cannabis-use Disorders
Behavioral Effects of Pregabalin and Cannabis
Cannabis is the most commonly used illicit drug in the United States, and its use is associated with rates of development of abuse and dependence, treatment admission and relapse that are comparable to other illicit drugs.
- Trial name
- NCT01511640
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Joshua A. Lile, Ph.D.
Addiction, Internet Gaming Disorder
The Effectiveness of tDCS on Internet Game Addiction
In this study, the investigators aimed to investigate the effect of transcranial direct current stimulation (tDCS) on clinical status of Internet game addiction.
- Trial name
- NCT03347643
- Testing
- tDCS with real stimulation
- Where
- South Korea
- Volunteers
- 31 people
- Sponsor
- Seoul National University Hospital
Drug Craving Levels Among Individuals With Substance Addiction, Depression Levels Among Individuals With Substance Addiction
The Effects of Exercise and Music Combination on Drug Cravings, Depression and Self-Efficacy Among Drug Addicts
This study focuses on the rehabilitation of drug addicts by combining exercise and music, to find out whether exercise and exercise combined with music of different rhythms will have an improvement for drug addicts. 1.
- Conditions
- Drug Craving Levels Among Individuals With Substance Addiction, Depression Levels Among Individuals With Substance Addiction, Self-efficacy Among Individuals With Substance Addiction
- Trial name
- NCT07279246
- Testing
- Sports group, Exercise combined with fast-paced music group, Exercise combined with slow-tempo music group
- Where
- Malaysia
- Volunteers
- 92 people
- Sponsor
- WEIPENG DUAN
Obesity
Neuromolecular Risk Factors for Obesity (PROSPECT)
The goal of this project is to characterize the neural and psychological mechanisms that contribute to development of obesity in the early adulthood.
- Trial name
- NCT03106688
- Testing
- fMRI imaging, [11C]carfentanil PET scan, [18F]FMPEP-d2 PET scan
- Where
- Finland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Substance-Related Disorders, Treatment Adherence
Motivational Interviewing at Intake vs Intake as Usual on Client Engagement in Addiction Treatment
This K23 study is an effectiveness-implementation hybrid type I design to determine the effectiveness of Motivational Interviewing at Intake (MII), relative to intake-as-usual on client engagement and mechanisms of engagement…
- Trial name
- NCT05489068
- Testing
- Motivational Interviewing at Intake (MII), Intake as Usual (IAU)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of New Mexico
Marijuana Dependence
Effect of Oxytocin on Stress in Marijuana Users
The purpose of this study is to evaluate how people who frequently use marijuana respond to a stressful task, and if a medication (oxytocin) affects this response.
- Trial name
- NCT01335789
- Testing
- Oxytocin, Saline
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Medical University of South Carolina
Technology Addiction, Public Health Nursing
The Effect Of Technology Addiction Prevention Program On University Students At Risk For Technology Addiction
Due to the increasing use of technological devices among adolescents, technology addiction is a serious public health problem that requires intervention.
- Conditions
- Technology Addiction, Public Health Nursing, School Health
- Trial name
- NCT06918691
- Testing
- technology addiction prevention program
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Alcohol Dependence
High-dose Accelerated Theta Burst Stimulation for the Treatment of Alcohol Addiction
This is a two-arm randomized placebo-controlled trial in which 72 patients with alcohol addiction are treated with high-dose accelerated intermittent theta burst stimulation (TBS).
- Trial name
- TBA (NCT05738174)
- Testing
- high-dose accelerated intermittent theta burst stimulation
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Berthold Langguth, MD, Ph.D.
Tobacco Smoking, Nicotine Dependence
Effects of Intensive Behavioral Training Program on Impulsivity and Inhibitory Control in Smokers
Dependence on tobacco derived nicotine is a major public health problem. Substance users who complete training in mindfulness subjectively report increased patience and improved motor control over their impulses.
- Conditions
- Tobacco Smoking, Nicotine Dependence, Impulsivity, Addiction
- Trial name
- IBTP (NCT01314378)
- Testing
- Mindfulness Training, Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Addiction
Lamotrigine for Ketamine Dependence Trial
The purpose of this study is to investigate the efficacy of lamotrigine in the treatment of ketamine dependence in a double-blind, placebo controlled design.
- Trial name
- NCT02556060
- Testing
- Lamotrigine
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei City Hospital
Sarcopenia, Occlusion
Effectiveness of Focal Vibration and Blood Flow Restriction Within a Multicomponent Exercise Programme.
Sarcopenia can occur or increase due to sedentary lifestyles, physical inactivity or chronic endocrine and inflammatory disorders, this pathology is much more frequent in older people due to the added risk factors and the fact…
- Conditions
- Sarcopenia, Occlusion, Vibration; Exposure, Old Age; Atrophy
- Trial name
- NCT04940702
- Testing
- Focal Vibration, Blood Flow Restriction, Traditional Training
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universitat Internacional de Catalunya
Opioid Use Disorder
Following Outcomes Remotely Within Addiction Recovery Domains
The aim of this study is to describe outcome of people with opioid use disorder over the long-term by collecting monthly and yearly data on their recovery.
- Trial name
- FORWARD (NCT06001437)
- Where
- United States
- Volunteers
- 369 people
- Sponsor
- Mclean Hospital
Tobacco Use Disorder
Increasing Smoking Cessation Success Through Sleep-amplified Memory Consolidation
The goal of this subproject is to examine the hypothesized improvement of treatment with chess-based training and sleep enhancement, both together and on their own, in smokers.
- Trial name
- NCT05726045
- Testing
- Standard smoking cessation program (SCP), Cognitive remediation treatment (CRT), High-intensity interval training (HIIT evening)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Nicotine Addiction, Drug Addiction
Clinical Trial of Smoking Cessation Mobile Phone Program
The Sponsor is doing a research study to assess the effects of a smartphone program designed to help users smoke less and eventually quit. When participants join, their involvement in the core study will last 8 weeks.
- Conditions
- Nicotine Addiction, Drug Addiction, Drug Dependence, Substance Use Disorder
- Trial name
- NCT02656745
- Testing
- Mobile Smoking Cessation Solution
- Where
- United States
- Volunteers
- 416 people
- Sponsor
- Click Therapeutics, Inc.
Addiction, Alcohol, Urinary Tract Disease
Does Homebrewing Beer Affect Urinary Tract Symptoms and Bladder Cancer
In this study, investigators aim to reveal the harmful effects of increasing consumption of homemade beer in recent years on the urinary tract.
- Trial name
- NCT05134675
- Testing
- Homemade beer
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Sports Physical Therapy
Smartphone Addiction and Physical Activity
This study aimed to determine the effect of smartphone addiction on physical activity level in healthy individuals. A total of 300 (134 female) healthy university students were included in this study.
- Trial name
- NCT04299074
- Testing
- addiction
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Pamukkale University