Clinical trials: Addictive, open to volunteers
Sexual Addiction
Prevalence of Sexual Addiction in an Inmate Population at the Muret Detention Center in Haute-Garonne (PAS-CD)
Sexual addiction, also known as hypersexuality or compulsive sexuality, is a human sexual behavior that results in a continuous and persistent search for sexual pleasure.
- Trial name
- PAS-CD (NCT05483426)
- Testing
- semi-structured Interviews
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Federation Regionale de Recherche en Psychiatrie et Sante Mentale Occitanie
Tobacco-Related Carcinoma, Addiction
Comparative Evaluation of Nicotine Analogs
This phase I trial compares electronic cigarette (EC) user preferences and smoking behaviors of nicotine analogs to nicotine to improve the understanding of nicotine analog addictiveness.
- Trial name
- CENA (NCT07585006)
- Testing
- Biospecimen Collection, Nicotine, 6-Methyl Nicotine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Addiction
Efficacy of a Smartphone App. Designed to Manage Craving & Individual Predictors of Substance Use/Addictive Behavior
Test the Efficacy of a smartphone application designed to manage craving and individual predictors of substance use / addictive behavior among individuals with addictive disorders
- Trial name
- CRAVINGMANAGER (NCT04732676)
- Testing
- Smartphone application
- Where
- France
- Volunteers
- 274 people
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Obesity
Situation and Evolution of the Misuse of Alcohol and Other Addictive Behaviors in Obese Patients Being Managed at Nîmes University Hospital
Obesity is a multifactorial pathology in which external (lifestyle, environment) and internal (psychological or biological, especially genetic) factors are involved. These are responsible for a positive energy balance.
- Trial name
- ADOB (NCT04613791)
- Testing
- Blood test
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Smoking ( Cigarette)
Impact of Sweeteners on the Addictive Threshold of Nicotine
To determine if sucralose, an artificial sweetener, modulates nicotine threshold doses for discrimination, subjective-rewarding effects, and reinforcement in smokers with varying levels of dependence.
- Trial name
- NCT07771725
- Testing
- Nicotine 0.05 mg/pulse and 0.1 mg/pulse, sucralose
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Yale University
Addiction Disorders, Addictive Behaviors
Understanding the Long-term Paths of People With Addictions
The study is an open prospective cohort study. Participants are assessed at the start of their care in an addiction treatment unit using the Addiction Severity Index (ASI) and the Mini International Neuropsychiatric Interview…
- Conditions
- Addiction Disorders, Addictive Behaviors, Addiction
- Trial name
- ADDICT AQUI (NCT07249970)
- Testing
- Addiction Severity Index
- Where
- France
- Volunteers
- 10,000 people
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Smartphone Addiction
Smartphone Use and Hand Function in Young Adults
This observational cross-sectional study aims to investigate the relationship between daily smartphone usage duration and hand function parameters in young adults.
- Trial name
- NCT07540546
- Testing
- Assessment Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Opioid Use Disorder, Opioid Abuse and Addiction
GLP-1R Agonist Treatment for Opioid Use Disorder
The goal of this clinical trial is to learn if semaglutide can reduce illicit opioid use in adults in outpatient treatment for opioid use disorder, and who are receiving either buprenorphine or methadone maintenance treatment.
- Conditions
- Opioid Use Disorder, Opioid Abuse and Addiction, Narcotic-Related Disorders, Substance-Related Disorders
- Trial name
- NCT06548490
- Testing
- Semaglutide Pen Injector
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Milton S. Hershey Medical Center
Smoking Addiction
Addictive Threshold of Nicotine
To determine the nicotine threshold dose(s) for discrimination, subjective-rewarding effects, -and reinforcement in smokers with different levels of dependence.
- Trial name
- NCT06096714
- Testing
- Nicotine, Saline
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Yale University
Addictions
téléwork and Consumer Behavior: Longitudinal Study
Alcohol and nutritional factors are among the leading causes of preventable cancer. Knowing that so many health problems could be avoided thanks to behavioral changes, the identification of the factors at the origin of these…
- Trial name
- SUBSTANCES_1 (NCT07788352)
- Testing
- data collection
- Where
- France
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Université de Reims Champagne-Ardenne
Tension-Type Headache, Sleep Disturbance
Tension-type Headache and Its Association
To estimate the prevalence of tension-type headache among adults attending the outpatient clinics at Assiut University Hospitals, and to assess its association with smartphone use, sleep quality, and quality of life.
- Conditions
- Tension-Type Headache, Sleep Disturbance, Smartphone Addiction, Quality of Life
- Trial name
- NCT07779655
- Volunteers
- 199 people
- Sponsor
- Assiut University
Depression in Adolescence, Suicidal Ideation
Social Media Concerns Related to Emotional Experiences in Naturalistic Settings (SCREENS)
The objective of this study is to advance understanding of the relationships between social media use (SMU) and internalizing symptoms among a diverse sample of depressed and/or suicidal youth.
- Conditions
- Depression in Adolescence, Suicidal Ideation, Social Media Addiction, Mental Health Issue
- Trial name
- SCREENS (NCT07278752)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Texas Southwestern Medical Center
Smoking, Smoking Cessation
A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home
The purpose of this study is to evaluate how using an indoor air quality monitor can promote a smoke-free home for cancer patients who are enrolled in MSK's Tobacco Treatment Program.
- Conditions
- Smoking, Smoking Cessation, Smoking Reduction, Smoking Habit
- Trial name
- NCT06693700
- Testing
- Indoor Air Quality Monitor AirGradient ONE
- Where
- 8 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Internet Gaming Disorder
Virtual Reality Exercise for Young Adults at Risk of Digital Gaming Addiction
Digital game addiction is associated with reduced physical activity, increased sedentary behavior, and adverse physical and psychosocial health outcomes in young adults.
- Trial name
- VR-GAME (NCT07718763)
- Testing
- Traditional Aerobic Exercise, Virtual Reality-Based Aerobic Exercise
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Alcohol Use Disorder (AUD)
Renewed Recovery: a Pilot Test of a Web-Based Mindfulness-Based Relapse Prevention Continuing Care Intervention for Alcohol Use Disorder
This study aims to design, implement, and evaluate a pilot test of a web-based Mindfulness-Based Relapse Prevention (MBRP) continuing care intervention to support individuals with alcohol use disorder (AUD) exiting standard…
- Trial name
- NCT06987526
- Testing
- Mindfulness-Based Relapse Prevention
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Georgia
Tiletamine Use Disorder, Substance Use Disorder (SUD)
The Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation in Individuals With Tiletamine Use Disorder
Participants diagnosed with tiletamine use disorder will be assigned to active or sham taVNS for 5 days. Clinical outcomes ( e.g., behavioral paradigms measures and clinical scales ) and physiological markers (e.g., EEG and ECG)…
- Conditions
- Tiletamine Use Disorder, Substance Use Disorder (SUD), Drug Craving
- Trial name
- taVNS-Tiletami (NCT07689981)
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Mental Health Center
Alcohol Use Disorder
Deep Brain Stimulation to Understand and Treat Addiction
This study is testing whether deep brain stimulation (DBS) can safely help people with severe alcohol use disorder who have not improved with standard treatments.
- Trial name
- Brain-PACER (NCT07341230)
- Testing
- Dual-Target Deep Brain Stimulation, Nucleus Accumbens Deep Brain Stimulation, Ventral Internal Capsule Deep Brain Stimulation
- Where
- 2 sites in United Kingdom
- Volunteers
- 9 people
- Sponsor
- University of Cambridge
Tobacco Use Disorder
Increasing Smoking Cessation Success Through Sleep-amplified Memory Consolidation
The goal of this subproject is to examine the hypothesized improvement of treatment with chess-based training and sleep enhancement, both together and on their own, in smokers.
- Trial name
- NCT05726045
- Testing
- Standard smoking cessation program (SCP), Cognitive remediation treatment (CRT), High-intensity interval training (HIIT evening)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Prevention, Digital Health
Digital Detox Study
The Digital Detox study is designed as a randomized controlled trial (two unblinded parallel groups) to examine the effects of reducing smartphone screentime on mental health.
- Conditions
- Prevention, Digital Health, Smartphone Addiction
- Trial name
- RESET (NCT06910371)
- Testing
- smartphone screen time reduction
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Danube University Krems
Eating Disorders in Adolescence, Food Addiction
Evaluation of a Digital School-Based Intervention for the Primary Prevention of Eating Disorders in Pre-Adolescents (PRETA Program)
Background: Eating Disorders (ED) are mental health conditions, characterized by pathological behaviors toward food intake or a persistent obsession with weight control.
- Trial name
- PRETA (NCT06792981)
- Testing
- Universal primary prevention program based on ICTs
- Where
- Spain
- Volunteers
- 1,068 people
- Sponsor
- Servicio Canario de Salud