Clinical trials: Addictive, open to volunteers
Addiction Disorders, Addictive Behaviors
Understanding the Long-term Paths of People With Addictions
The study is an open prospective cohort study. Participants are assessed at the start of their care in an addiction treatment unit using the Addiction Severity Index (ASI) and the Mini International Neuropsychiatric Interview…
- Conditions
- Addiction Disorders, Addictive Behaviors, Addiction
- Trial name
- ADDICT AQUI (NCT07249970)
- Testing
- Addiction Severity Index
- Where
- France
- Volunteers
- 10,000 people
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Obesity
Situation and Evolution of the Misuse of Alcohol and Other Addictive Behaviors in Obese Patients Being Managed at Nîmes University Hospital
Obesity is a multifactorial pathology in which external (lifestyle, environment) and internal (psychological or biological, especially genetic) factors are involved. These are responsible for a positive energy balance.
- Trial name
- ADOB (NCT04613791)
- Testing
- Blood test
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Opioid Use Disorder, Methadone
Evaluating Tetrahydrocannabinol as an Adjunct to Opioid Agonist Therapy
This pilot study will evaluate the feasibility and safety of using 1:1 tetrahydrocannabinol (THC):Cannabidiol (CBD) cannabis oil as an adjunct therapy to methadone-based Opioid Agonist Therapy (OAT) for individuals with opioid…
- Conditions
- Opioid Use Disorder, Methadone, Cannabis, Fentanyl
- Trial name
- THC-MMT (NCT05985850)
- Testing
- Aurora 1:1 Drops (Indica)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- BC Centre on Substance Use
Sleep Disorder
Targeted Intervention on Sleep Disorders During Tobacco or Cannabis Cessation Therapy
During a cessation therapy for tobacco or cannabis, sleep disorders are one of the main risk factors of relapse, and a symptom of substance withdrawing.
- Trial name
- ISAC (NCT07202351)
- Testing
- Screening and management of sleep disorders
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier St Anne
Pregnant Woman Who Uses Tobacco
Assessement of a Test a Financial-incentive Program for Pregnant Women and Their Smoking Partners to Reduce Smoking During Pregnancy.
Nearly one in five pregnant women still smoke in the third trimester of pregnancy. This is the highest rate in Europe. Smoking during pregnancy is an established risk factor for the unborn child: risk of ectopic pregnancy…
- Trial name
- PREVENT (NCT07528664)
- Testing
- Financial incentive contingent on tobacco abstinence., Standar care
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Lille
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Internet Addiction
Interpersonal Relational Role Analysis Group Therapy for Nursing Students at Risk of Internet Addiction
Internet addiction risk among nursing students may be associated with difficulties in emotion regulation, loneliness, and interpersonal relationships.
- Trial name
- Interpersonal (NCT07907133)
- Testing
- KAİRA
- Volunteers
- 60 people
- Sponsor
- Aydin Adnan Menderes University
Addiction
Efficacy of a Smartphone App. Designed to Manage Craving & Individual Predictors of Substance Use/Addictive Behavior
Test the Efficacy of a smartphone application designed to manage craving and individual predictors of substance use / addictive behavior among individuals with addictive disorders
- Trial name
- CRAVINGMANAGER (NCT04732676)
- Testing
- Smartphone application
- Where
- France
- Volunteers
- 274 people
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Alcohol Abuse, Alcohol Abuse/addiction
A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder
This study will evaluate the safety and exploratory efficacy of AFA-281 in patients with Alcohol use disorder on cravings, subjective response to alcohol, pain thresholds, anxiety, depression, and sleep.
- Conditions
- Alcohol Abuse, Alcohol Abuse/addiction, Anxiety, Pain Threshold
- Trial name
- NCT06710431
- Testing
- AFA-281
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Afasci Inc
Alcohol Use Disorder
Peer Support in Alcohol Dependence
Alcohol use disorder (AUD) affects between 4% and 6% of French adults, and requires appropriate medical treatment. However, 20-40% of patients with AUD are lost to follow-up at an early stage.
- Trial name
- PEERSIAD (NCT06381609)
- Testing
- Quality life questionnaire AQoLS, Quality life questionnaire Euroqol EQ-5D-5L, Peer support consultations
- Where
- 5 sites in France
- Volunteers
- 626 people
- Sponsor
- Hospices Civils de Lyon
Tobacco Use Cessation, Addiction
An Evaluation of the Tobacco Prevention Toolkit Healthy Futures: Alternative-to-Suspension Vaping Intervention
The Healthy Futures: Alternative-to-Suspension Curriculum is a free, online curriculum developed to educate students and provide them with resources to quit tobacco/nicotine use.
- Trial name
- NCT06483412
- Testing
- Healthy Futures: Alternative-to-Suspension Curriculum
- Where
- United States
- Volunteers
- 2,540 people, healthy volunteers welcome
- Sponsor
- Stanford University
Mental Health Issue
The Relationship Between Internet-use Behavior and Mental Health in Youth
Introduction: WHO defines youth as 15-24 years age group. At this stage, the brain is still under development, with high impulsiveness, being fond of stimulation and yearning for peer life.
- Trial name
- NCT06284551
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Healthy
Analysis of Internet Addiction, Musculoskeletal Pain and Body Awareness in High School Students
The study will investigate internet addiction, musculoskeletal pain and body awareness in high school students.
- Trial name
- NCT05636137
- Testing
- Survey application
- Where
- Turkey (Türkiye)
- Volunteers
- 213 people
- Sponsor
- Muğla Sıtkı Koçman University
Opioid Dependence, Opioid Use Disorder (OUD)
VK4-116 Phase I Study With Food-Effect
This first-in-human, randomized, double-blind, placebo-controlled, single ascending dose (SAD), phase I study is designed to assess the safety, tolerability and pharmacokinetics of VK4-116 in healthy volunteers in fasted and fed…
- Trial name
- NCT06808932
- Testing
- VK4-116
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Addiction
Support Towards Addiction Recovery for Individuals With Criminal Legal System Involvement: The STAR Project
The goal of this clinical trial is to determine whether a new, paired coaching intervention improves outcomes for individuals with criminal legal system involvement recovering from substance use disorder, as well as the loved…
- Trial name
- NCT07596251
- Testing
- STAR Intervention
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Martha Tillson
Addiction, Alcohol, Addiction, Substance
Efficiency of Prevention Program Dedicated to Addictive Behaviors (PREVENTURE) of Vulnerable Teenagers
At the age of 17, in Brittany, 94.9% of adolescents have experimented alcohol consumption 78.1% within a month and 25.5% report repeated episodes of Intensive Punctual Alcohol.
- Trial name
- PREVADO (NCT04599270)
- Testing
- PREVENTURE Program, Routine care
- Where
- 5 sites in France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Brest
Substance Use Disorder (SUD)
Fighting Addictions, Improving Lives: COmprehensive Drug Rehabilitation With Music
FALCO is a parallel pragmatic randomized control trial addressing long-term effects of music therapy (MT) on substance use disorder (SUD). 600 participants will be recruited from multiple European countries (see Locations).
- Trial name
- FALCO (NCT07028983)
- Testing
- Active Music Group (AMG), Music Listening Group (MLG), Treatment as Usual (TAU)
- Where
- 11 sites in Austria, Israel and 6 more
- Volunteers
- 600 people
- Sponsor
- NORCE Norwegian Research Centre AS
Opioid-Related Disorders, Drug Addiction
Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder
Background: People with addictions often find it hard to choose the long-term benefits of abstinence over the short-term effects of using drugs.
- Trial name
- NCT03745339
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Hepatitis C, Transmission, Intravenous Drug Abuser
Acceptability of Simultaneous Screening for Viral Hepatitis B, C and HIV Among Drug Users in Non-conventional Structures
The principle is to propose dedicated monthly screening days bringing together the health personnel involved (hepatologist, addictologist, nurse in charge of the program, addictology nurse and social worker) and to propose…
- Conditions
- Hepatitis C, Transmission, Intravenous Drug Abuser, Addiction, Alcohol, Addiction Opiate
- Trial name
- SCANVIR (NCT05361603)
- Where
- France
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Paraphilic Disorders, Sexual Addiction
Paraphilic Disorders and Other Conditions With Risk for Sexual Violence: a Case-control Study
The goal of this case-control study is to compare clinical characteristics in help-seeking individuals with paraphilic disorders or sexsomnia (sexual behaviors during sleep- a diagnosis in the American Psychiatric Association's…
- Conditions
- Paraphilic Disorders, Sexual Addiction, Parasomnia
- Trial name
- NCT05861752
- Testing
- Treatment as usual
- Where
- Sweden
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Region Stockholm