Clinical trials: Addictive Behavior
Substance Abuse
Web-delivery of Evidence-based, Psychosocial Treatment for Substance Use Disorders
The main objective of this study is to evaluate the effectiveness of including an interactive, web-based version of the Community Reinforcement Approach (CRA), called the Therapeutic Education System (TES), as part of…
- Trial name
- CTN-0044 (NCT01104805)
- Testing
- Therapeutic Education System (TES), Treatment-as-Usual (TAU)
- Where
- 10 sites in United States
- Volunteers
- 507 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Psychoactive Substances Consumers
Evaluation of Relationship Between Hypersexuality and Psychostimulant Among Men Who Have Sex With Men
Survey of fifty new psychoactive substances consumers in a context of MTM sexual intercourse. Evaluation using an hetero-assessment questionnaire about the link between hypersexual disorder and the use of synthetic cathinone.
- Trial name
- HYPERCHEM (NCT02969694)
- Testing
- G-STAT questionnaire
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Hospices Civils de Lyon
Substance Use Disorder, Cocaine Dependence
Cannabidiol and Cocaine Craving/Dependence
In this study, the investigators seek to evaluate the effects of cannabidiol (CBD) on cocaine craving and relapse. Cocaine addiction is characterized by compulsive substance use and repetitive urges to consume the drug even after…
- Conditions
- Substance Use Disorder, Cocaine Dependence, Withdrawal From Addictive Substance; Detoxification
- Trial name
- CBD (NCT02559167)
- Testing
- Cannabidiol
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Tobacco Use Disorder, Nicotine Dependence
The MATCH (Medication Aids for Tobacco Cessation and Health) Study
Clinically proven medications such as nicotine replacement therapy, bupropion and varenicline are available to help smokers quit but there are not widely used.
- Trial name
- MATCH (NCT02146911)
- Testing
- Bupropion, Varenicline, Weekly Motivational Emails
- Where
- Canada
- Volunteers
- 968 people
- Sponsor
- Centre for Addiction and Mental Health
Parkinson's Disease, Secondary Behavioural Addiction
Behavioural Addictions Occurring During a Dopaminergic Treatment Prescribe Under Parkinson's Disease: Study of the Psychopathological, Neurological, Pharmacokinetic and Genetic Profiles
This study is composed of a main study and an ancillary one. The objective of the main study is to define, on the psychopathological, neurological, pharmacokinetic and genetic plan, the predictive factors for developing a…
- Trial name
- PARKADD (NCT01733199)
- Testing
- questionnaires
- Where
- France
- Volunteers
- 225 people
- Sponsor
- Nantes University Hospital
Tobacco Smoking
The Effects of Sedatives on Tobacco Use Disorder Version 2
Double-blind, placebo-controlled, randomized mechanistic clinical trial to test an intravenous dose of either ketamine, midazolam, dexmedetomidine, or a placebo (saline) on cigarette smoking behavior, craving, and neural effects.
- Trial name
- SED-TUD2 (NCT05505630)
- Testing
- Ketamine, Midazolam, Dexmedetomidine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Nicotine Dependence, Smoking
Exercise Training for Smoking Students
Smoking can damage lung functions as a result of high carbon monoxide and low hemoglobin oxygen carrying capacity in the blood. Smoking between young people continues to increase, which can cause respiratory function problems and…
- Conditions
- Nicotine Dependence, Smoking, Physical Inactivity, Depression
- Trial name
- NCT06291558
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Narcotic Addiction
Auricular Acupuncture to Facilitate Outpatient Opioid Weaning
This study is to compare two groups undergoing opioid weaning as ordered by their referring physicians. One group will undergo the standard opioid weaning process and the other group will have the addition of the NADA Protocol to…
- Trial name
- NCT02882048
- Testing
- NADA Protocol, Medication management
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Vanderbilt University Medical Center
Cigarette Smoking, Tobacco Smoking
Mindfulness Training for Smoking Cessation
The purpose of this study is to assess the effects of mindfulness training (MT) compared to standard Smoking Cessation Therapy (SCT) on smoking cessation and stress provocation in individuals trying to quit smoking.
- Conditions
- Cigarette Smoking, Tobacco Smoking, Nicotine Dependence, Smoking Cessation
- Trial name
- NCT01144689
- Testing
- Mindfulness Training, Smoking Cessation Therapy
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Yale University
Amphetamine Addiction
The Novel Addiction Assessment Study in Synthetic Drugs Addiction
The purpose of this research is to develop an objective assessment based on the virtual reality techniques which is used for evaluate addiction severity.
- Trial name
- NCT02950376
- Testing
- DSM-5 +Virtual reality-based addiction assessment system, Virtual reality-based addiction assessment system
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Chronic Pain, Behavior, Addictive
Health Outcomes From Opioid Therapy for Chronic Pain
Although the use of opioid medications has gained increasing acceptance as a treatment option for chronic pain, there is little empirical research concerning long-term outcomes with this patient population.
- Trial name
- NCT00495404
- Testing
- Physician Treatment Guidelines
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- US Department of Veterans Affairs
Buprenorphine, HIV
Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM)
The purpose of this study is to assess the feasibility, cost and effectiveness of interventions designed to integrate buprenorphine treatment for opioid dependence into HIV primary care in ten HIV care centers in the U.S.
- Conditions
- Buprenorphine, HIV, Drug Abuse, Drug Addiction
- Trial name
- BELIEVE (NCT00798538)
- Testing
- Services will be provided at one site, Services remain dispersed; i.e., not centralized to one-location or provider.
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
Heroin Dependence
Naltrexone and Adrenergic Agents to Reduce Heroin Use in Heroin Addicts
Naltrexone is a medication that is currently used to treat drug and alcohol addiction. Guanfacine is a medication that is currently used to manage the withdrawal symptoms in individuals undergoing opioid detoxification.
- Trial name
- NCT00142948
- Testing
- Naltrexone
- Where
- Russia
- Volunteers
- 301 people
- Sponsor
- Baylor College of Medicine
Addiction
A Study to Assess 18-Methoxycoronaridine (18-MC HCl) in Healthy Volunteers
The primary objective of this study is to assess the safety and tolerability of a single day dosing and a separate multiple day dosing of 18-MC HCl administered orally, each part of the study having a different set of healthy…
- Trial name
- NCT04292197
- Testing
- 18-MC Compound
- Where
- Australia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Definium Therapeutics US, Inc.
Smoking (Tobacco) Addiction
Impact of Exercise Associated With Cognitive-behavioral Therapy in Smokers
Smoking remains one of the leading causes of global morbidity and mortality, responsible for more than 8 million deaths annually, according to data from the World Health Organization.
- Trial name
- NCT07186049
- Testing
- Thesis Sessions, General Health Guidelines, Thesis and Exercises
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Agnaldo José Lopes
Social Media Addiction
Roy Adaptation Model Based Strengthening Program and Social Media Addiction
In this pretest-posttest, randomized controlled study, the effect of the empowerment program developed based on Roy Adaptation on the healthy lifestyle behaviors, self-esteem and social media addiction of nursing students will be…
- Trial name
- NCT04820517
- Testing
- Roy Adaptation Model Based Strengthening Program
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Mersin University
Exercise Addiction, Sleep Disorder
The Effects of Exercise Training in Community-dwelling Elderly With Sleep Disturbances With Follow-up
This study will explore the long-term effects of exercise training on body composition, cardiorespiratory fitness, and energy metabolism in the community-dwelling elderly with sleep disturbances
- Trial name
- NCT03005990
- Testing
- Exercise training group
- Where
- Taiwan
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Methamphetamine-dependence, Transcranial Direct Current Stimulation
Transcranial Direct Current Stimulation (tDCS) Combined With Computerized Cognitive Addiction Therapy(CCAT) and, Electronic Follow-up for Methamphetamine(MA) Dependent Patients
Transcranial direct current stimulation (tDCS) combined with computerized cognitive addiction therapy(CCAT) for methamphetamine(MA) dependent patients in voluntary drug rehabilitation center.
- Conditions
- Methamphetamine-dependence, Transcranial Direct Current Stimulation, Computerized Cognitive AddictionTherapy, Electronic Health Records
- Trial name
- NCT04139148
- Testing
- Ture Transcranial Direct Current Stimulation (tDCS)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Mental Health Center
Addiction
Reducing the Abuse Liability of Prescription Opioids
Opioid (commonly called narcotic) pain medicines are, after marijuana, the most commonly abused substances in the United States.
- Trial name
- NCT04587115
- Testing
- Risperidone, Ziprasidone, Oxycodone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Self Efficacy
Substance Use Risk and Solution-Focused Approach
Although substance abuse is the subject of serious struggles on the basis of individuals and countries, its rate of spread cannot be stopped and it creates an agenda with new people added every day.
- Trial name
- NCT06732206
- Testing
- Short Solution Focused Approach Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ufuk DOĞAN