Clinical trials: Addictive Behaviors, open to volunteers
Parenting, Social Media Addiction
Digital Parenting Education: Impact on Mothers' Social Media Use and Children's Tech Attitudes
The aim of the study was to evaluate the knowledge and attitudes of mothers regarding social media addiction and their children's technology use. The research is a randomized controlled trial.
- Conditions
- Parenting, Social Media Addiction, Internet Addiction
- Trial name
- NCT07008651
- Testing
- Digital parenting education
- Where
- Turkey (Türkiye)
- Volunteers
- 152 people
- Sponsor
- Artvin Coruh University
Tobacco-Related Carcinoma, Addiction
Comparative Evaluation of Nicotine Analogs
This phase I trial compares electronic cigarette (EC) user preferences and smoking behaviors of nicotine analogs to nicotine to improve the understanding of nicotine analog addictiveness.
- Trial name
- CENA (NCT07585006)
- Testing
- Biospecimen Collection, Nicotine, 6-Methyl Nicotine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Alcohol Use Disorder, Alcohol Use Disorder (AUD)
Optimizing Smart Technology for Addiction Recovery
The goal of this study is to develop a machine-learning guided recovery messaging system. The main question it aims to answer is can messages be used to: help people to improve their health make changes in people's lives to…
- Trial name
- STAR (NCT07573540)
- Testing
- STAR
- Where
- United States
- Volunteers
- 416 people
- Sponsor
- University of Wisconsin, Madison
Opioid Use Disorder, Opioid Abuse and Addiction
GLP-1R Agonist Treatment for Opioid Use Disorder
The goal of this clinical trial is to learn if semaglutide can reduce illicit opioid use in adults in outpatient treatment for opioid use disorder, and who are receiving either buprenorphine or methadone maintenance treatment.
- Conditions
- Opioid Use Disorder, Opioid Abuse and Addiction, Narcotic-Related Disorders, Substance-Related Disorders
- Trial name
- NCT06548490
- Testing
- Semaglutide Pen Injector
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Milton S. Hershey Medical Center
Food Addiction
Ultra Crave: An Investigation of Ultra-Processed Food
This study experimentally investigates whether a reduction in ultra-processed (UP) food intake (1) causes aversive withdrawal symptoms in humans, (2) increases the motivational salience of UP food cues and, if so, (3) whether…
- Trial name
- NCT06044285
- Testing
- Low UP (meals provided), Low UP (self-guided), Active Control
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- University of Michigan
Addiction
Role of Craving in the Transition Across Level of Addiction Severity: A Longitudinal Study.
Substance/Alcohol Use disorders are defined as a loss of control over the use despite harmul consequences, as well as an intense and persistent urge to use, also called craving.
- Trial name
- CARDEMA (NCT07734363)
- Testing
- Observational assessments (EMA and annual DSM-5 evaluations)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University of Bordeaux
Alcoholic Liver Disease
French National MICMAF Cohort
Excessive alcohol consumption is a major public health problem, particularly in France. It is the leading cause of cirrhosis and hepatocellular carcinoma.
- Trial name
- MICMAF (NCT05895890)
- Testing
- Sequential sampling (stool, saliva, serum) .
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Trauma and Stress-related Disorders, Substance Use Disorder (SUD)
Protocol Study on Addiction, Trauma and Immigration Among Vulnerable Young Adults in Grand Est
The ATICC study (Addiction, Trauma, and Immigration, Prevention and Cross-Cultural Support for Care) investigates the complex relationships between trauma, substance use, migration experiences, and mental health perceptions among…
- Conditions
- Trauma and Stress-related Disorders, Substance Use Disorder (SUD), Substance Use Risk
- Trial name
- ATICC (NCT06922721)
- Testing
- Focus group
- Where
- 7 sites in France
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Lorraine
Alcohol Use Disorder, Cognition Disorders
Influence of Individual Traits on Adaptation Processes in Individuals With Alcohol Use Disorder
Alcohol Use Disorder (AUD) is a chronic condition that affects behavior, decision-making, and the ability to adapt to changing situations.
- Trial name
- TIPA (NCT07468825)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Substance-Related Disorders, Treatment Adherence
Motivational Interviewing at Intake vs Intake as Usual on Client Engagement in Addiction Treatment
This K23 study is an effectiveness-implementation hybrid type I design to determine the effectiveness of Motivational Interviewing at Intake (MII), relative to intake-as-usual on client engagement and mechanisms of engagement…
- Trial name
- NCT05489068
- Testing
- Motivational Interviewing at Intake (MII), Intake as Usual (IAU)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of New Mexico
Drug Addiction, Employment
Long-Term Treatment of Opioid Use Disorder
Poverty and opioid addiction are interrelated and chronic problems which have not been addressed adequately. The Therapeutic Workplace could treat the many adults with opioid use disorder who are unemployed and live in poverty.
- Trial name
- NCT05534815
- Testing
- Employment-based abstinence reinforcement
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Northern Michigan University
Brief Psychosocial Intervention
Psychosocial Support for Nitrous Oxide Misuse
Nitrous oxide (laughing gas, N₂O) is the third most commonly used recreational drug among young people in the UK. Although it may seem harmless, frequent use can damage the nerves and spinal cord.
- Trial name
- NCT07716293
- Testing
- Psychosocial intervention
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Queen Mary University of London
Paraphilic Disorders, Sexual Addiction
Paraphilic Disorders and Other Conditions With Risk for Sexual Violence: a Case-control Study
The goal of this case-control study is to compare clinical characteristics in help-seeking individuals with paraphilic disorders or sexsomnia (sexual behaviors during sleep- a diagnosis in the American Psychiatric Association's…
- Conditions
- Paraphilic Disorders, Sexual Addiction, Parasomnia
- Trial name
- NCT05861752
- Testing
- Treatment as usual
- Where
- Sweden
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Psychiatric Disorder
Evaluation of a Modularized Cognitive Behavioral Group Therapy Programme for Young Adults (CHANGE-Study)
This prospective, non-randomised, pre-post feasibility study evaluates CHANGE, a novel 8-session modularized cognitive behavioral group psychotherapy for young adults (18-25 years) with psychiatric disorders receiving inpatient…
- Trial name
- CHANGE (NCT07772180)
- Testing
- CHANGE - modularized group psychotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Max-Planck-Institute of Psychiatry
Depression, Anxiety
Ecological Momentary Assessment of State-Dependent Decision-Making and Metacognition Across a Psychopathology Continuum
Background: Making decisions during daily life is a complicated behavior. Even simple choices can be affected by a range of emotions, stresses, and moods.
- Conditions
- Depression, Anxiety, Addiction, Emotion
- Trial name
- NCT07801079
- Where
- 2 sites in United States
- Volunteers
- 420 people
- Sponsor
- National Institute of Mental Health (NIMH)
Alcohol Use Disorder, Insomnia
Daridorexant for People With Insomnia and Alcohol Use Disorder Study
The goal of this clinical trial is to see if a sleep medication, daridorexant (DTX), can help decrease drinking in people who have alcohol use disorder (AUD) and insomnia.
- Trial name
- DIAS (NCT07701928)
- Testing
- Daridorexant, Brief Counseling, MEMS and Medication Accounting
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- Sterling McPherson
Cancer
The SUNRISE Project is Dedicated to Enhancing Primary Cancer Prevention Among Adolescents in Europe by Leveraging Innovative Digital Tools and Methodologies. SmartCoach, Developed by Swiss Research Institute for Public Health and Addiction (ISGF), is a Mobile Phone-based Life-skills Training Program
SUNRISE aims to create a comprehensive, engaging, and sustainable digital health promotion program that not only addresses immediate health behaviours but also instills lifelong healthy habits among adolescents.
- Trial name
- SUNRISE_1 (NCT06922201)
- Testing
- SmartCoach
- Where
- 8 sites in Belgium, Cyprus and 6 more
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Biobizkaia Health Research Institute
Nicotine Use Disorder
Effects of Novel E-cigarette Constituents on Adults TCORS 3.0
This study is an examination of the influence of cooling components of WS-3, WS-23, and menthol on the appeal and addiction potential of nicotine-containing e-liquids among adults.
- Trial name
- NCT05932745
- Testing
- E-liquid coolant (No WS-3) for non-menthol (1), E-liquid coolant (No WS-3) for low (0.1%) menthol (1), E-liquid coolant (No WS-3) for high (2.0%) menthol (1)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Yale University
Social Skills, Primary Care
Social Skills in Chronic Pain, Addiction, Intimate Partner Violence and Primary Care
Context: psychosocial competencies (CPS) are higher cognitive functions defined by the ability to interact with others by adopting appropriate and positive behavior.
- Trial name
- Skills-PAVIP (NCT07145528)
- Testing
- Questionary with a case-report-form
- Where
- France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Alcohol Use Disorder, Stress Reaction
Neurobehavioral Profiles of Adaptive Stress Responses in Individuals With Alcohol Use Disorder
The goal of this observational study is to investigate longitudinal stress response profiles and adaptive versus non-adaptive stress responses in alcohol use disorder.
- Conditions
- Alcohol Use Disorder, Stress Reaction, Social Stress, Craving
- Trial name
- A03 (NCT06105853)
- Testing
- Trier Social Stress Test, Barlab Cue-Exposure, Functional magnetic resonance imaging
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Central Institute of Mental Health, Mannheim