Clinical trials: Adductor Canal Block
Healthy Human Volunteers
Continuous Adductor Canal Nerve Blocks: Relative Effects of a Basal Infusion v. Hourly Bolus Doses
Patients usually experience moderate-to-severe pain following the knee replacement that is often treated with a femoral nerve block (injection of numbing medicine placed around the main nerve of the knee joint).
- Trial name
- NCT02219438
- Testing
- Bolus, Basal
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
ACL Injury, Post Operative Pain
iPACK for Post-op Pain Following ACL Reconstruction
This study will consist of patients 12 years and older undergoing ACL reconstruction using a quadriceps or bone-patella tendon bone (BTB) graft.
- Trial name
- NCT05498870
- Testing
- Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + iPACK Block
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Medical University of South Carolina
Arthropathy of Knee
Adductor Canal Block Versus Femoral Nerve Block for Total Knee Arthroplasty
Peripheral nerve blocks catheters of the femoral nerve have long been used for perioperative analgesia in total knee arthroplasty (TKA). These blocks provide effective analgesia and patient satisfaction for surgical pain relief.
- Trial name
- NCT03133481
- Testing
- Adductor Canal Nerve Block, Femoral Nerve Block
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Anterior Cruciate Ligament Rupture
Adductor Canal Block and IPACK Block vs. Isolated Adductor Canal Block for Post-Operative Analgesia Following ACL Reconstruction With Bone Patellar Tendon Bone Autograft:
A randomized, single-blind, single-center study measuring the effects of adductor canal block combined with IPACK infiltration compared to adductor canal block alone on post-operative pain and opioid consumption in patients…
- Trial name
- NCT05286307
- Testing
- IPACK block
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- NYU Langone Health
Pain, Postoperative, Total Knee Arthroplasty (TKA)
Continuous Adductor Canal Blocks Vs. Low Dose Femoral Nerve Blocks For Early Rehabilitation After Total Knee Arthroplasty
Recently, several articles have suggested or reported that Adductor Canal Blocks (ACBs) offer adequate or equal analgesia and may promote better performance in early rehabilitation following Total Knee Arthroplasty (TKA) when…
- Trial name
- FemVsACB (NCT02453321)
- Testing
- Continuous Femoral Nerve Block, Nerve Block, Continuous Adductor Canal, Continuous Sciatic Nerve Block
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Kevin King, DO
Pain Management
Can Single-Injection Adductor Canal Blocks Improve PostOp Pain Relief in Patients Undergoing Total Knee Arthroplasty?
The purpose of the study is to determine the effect of a single injection adductor canal block (ACB) on pain scores within 24 hours post total knee arthroplasty (TKA).
- Trial name
- NCT02276495
- Testing
- ACB Control - 20 ml saline injection for ACB, ACB Study - 20 ml 0.5% Ropivacaine for Adductor Canal Block, Local infiltration - 100 mLs of a solution containing: Ropivacaine + Epinephrine + Ketorolac + Clonidine + 0.9% Normal saline
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of California, Irvine
Total Knee Athroplasty
Does PAI Reduce Pain After TKA Among Knee Arthroplasty Patients Receiving ACB & IPACK?
The goal of this clinical trial is to determine whether Periarticular Injection (PAI) alongside Adductor Canal Block (ACB) and Infiltration between the Popliteal Artery and Capsule of the Knee (IPACK) block can decrease…
- Trial name
- NCT04749615
- Testing
- Periarticular Injection (PAI), Saline Control Periarticular Injection (PAI)
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Hospital for Special Surgery, New York
Anterior Cruciate Ligament Tear, Knee Meniscus Tear
Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength
The purpose of this study is to compare the effects of a femoral nerve block vs. an adductor canal block on pain and quadriceps muscle strength for knee arthroscopy surgery.
- Trial name
- NCT05190120
- Testing
- Femoral Nerve Block, Adductor Canal Nerve Block, preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of California, San Francisco
Rupture of Anterior Cruciate Ligament, Tear of Anterior Cruciate Ligament
Trial Evaluating Postop Pain and Muscle Strength Among Regional Anesthesia Techniques for Ambulatory ACL Reconstruction
Despite the apparent multifaceted benefit in differentiating blockade sites and duration of nerve blockade, the efficacy of continuous adductor canal blockade utilized specifically in ACL reconstruction has not been extensively…
- Trial name
- NCT02584452
- Testing
- Mepivacaine, adductor canal continuous nerve catheter, Normal Saline as bolus followed by bupivacaine
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Vanderbilt University Medical Center
Post-operative Pain, Quadriceps Muscle Strength
Ultrasound Guided Adductor Canal Versus Femoral Nerve Blocks for Anterior Cruciate Ligament Reconstruction in Pediatrics
Both Ultrasound guided Adductor Canal Block ( ACB) and Femoral Nerve Block (FNB) has been used to provide postoperative analgesia for knee surgeries.
- Trial name
- NCT03053401
- Testing
- Adductor Canal Block, Femoral Nerve Block, Ultrasound
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Akron Children's Hospital
Postoperative Pain Following Knee Arthroplasty
Femoral Versus Adductor Canal Continuous Peripheral Nerve Blocks for Knee Arthroplasty
Patients typically experience moderate-to-severe pain following knee arthroplasty that is usually treated with a combination of oral and intravenous analgesics and enhanced by continuous peripheral nerve blocks.
- Trial name
- NCT01759277
- Testing
- Control: Femoral perineural local anesthetic infusion, Experimental: Adductor Canal perineural local anesthetic infusion
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, San Diego
Knee Arthropathy
Adductor Canal Block With Periarticular Injection and IPACK (ACB/PAI/IPACK) Versus Periarticular Injection (PAI)
A comparison of two pain control methods - the combination of Adductor Canal Block (ACB)/Periarticular Injection (PAI)/Infiltration of the interspace between the popliteal artery and the capsule of the posterior knee (IPACK)…
- Trial name
- IPACK (NCT03094663)
- Testing
- Bupivacaine with epinephrine, Methylprednisolone, Cefazolin
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Hospital for Special Surgery, New York
Osteo Arthritis Knee
Efficacy of Ipack Block and Surgeon's Joint Infiltration in Total Knee Arthroplasty
Total knee arthroplasty(TKA) is an effective modality for the treatment of advanced osteoarthritis of the knee joint with excellent outcomes.
- Trial name
- NCT03653416
- Testing
- Ipack, Bupivacaine, Peri Articular Infiltration
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Postoperative Analgesia, Medial Unicompartmental Knee Arthroplasty
Adductor Canal Block for Medial Compartment Knee Arthroplasty
This study will evaluate the affects of a single injection ultrasound-guided adductor canal block for patients undergoing robotic-assisted (MAKOplasty) medial UKA (unicompartmental knee arthroplasty).
- Trial name
- NCT01818531
- Testing
- Adductor canal block, Lumbar plexus block
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Wake Forest University Health Sciences
Osteo Arthritis Knee
Analgesic Value of Adductor Canal vs Femoral Block After Total Knee Arthroplasty
An observational study of the effect of femoral nerve block in addition to an adductor canal block for pain following total knee arthroplasty.
- Trial name
- NCT03395990
- Testing
- Active comparator: chloroprocaine
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Duke University
Total Knee Arthroplasty
Saphenous Nerve Block Versus Femoral Nerve Block for Total Knee Arthroplasty
Currently, the regional anesthetic standard of care for total knee replacement surgery is combined spinal/epidural, with or without a femoral nerve block, or FNB.
- Trial name
- NCT01333943
- Testing
- Study Group: Experimental, Control Group
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Hospital for Special Surgery, New York
Arthroplasty, Replacement, Knee, Nerve Block
Epidural Catheter With or Without Adductor Canal Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty
The purpose of this study is to further investigate the efficacy of adductor canal nerve blocks for pain management after total knee replacement.
- Trial name
- NCT02121392
- Testing
- Adductor Canal Nerve Block Catheter, Bupivacaine
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Pain
Liposomal Bupivacaine Versus Standard Bupivacaine in the Adductor Canal for Total Knee Arthroplasty
Study will evaluate the effect of liposomal bupivacaine versus standard bupivacaine on physical therapy measures and pain scores as well as opiate consumption.
- Trial name
- NCT03182933
- Testing
- Peripheral Nerve Blockade, 10 meter walk test on post-operative day 1, In person and over the phone questionnaire
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Wisconsin, Madison
Anterior Cruciate Ligament Tear
IPACK Versus Popliteal Sciatic Nerve Block in ACL Reconstruction
This is a prospective study comparing femoral nerve block plus sciatic nerve block to femoral nerve block plus infiltration of the posterior knee capsule (IPACK) in patients undergoing arthroscopic anterior cruciate ligament…
- Trial name
- NCT03983941
- Testing
- Ropivacaine injection
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Sujana Dontukurthy
Lower Extremity Surgery, Bunion
Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPAREL Admixed With Bupivacaine HCl vs. Bupivacaine HCl Administered as Combined Sciatic and Saphenous Nerve Blocks for Postsurgical Analgesia in Subjects Undergoing Lower Extremity Surgeries
This is a Phase 3, multicenter, randomized, double blinded, active controlled study in approximately 120 subjects undergoing lower extremity surgeries.
- Conditions
- Lower Extremity Surgery, Bunion, Metatarsophalangeal Fushion, Midfoot Fusion
- Trial name
- STRIDE (NCT04518462)
- Testing
- Exparel, Bupivacaine Hydrochloride
- Where
- 5 sites in United States
- Volunteers
- 121 people
- Sponsor
- Pacira Pharmaceuticals, Inc