Clinical trials: Adenocarcinoma of the Prostate
Prostate Cancer (Adenocarcinoma)
Understanding the Benefits of Dietary Fibre Supplementation in Patients With Prostate Cancer
The digestive tract (large intestine) contains microorganisms that digest complex carbohydrates in food to produce chemical substances which are beneficial to human health.
- Trial name
- EVENTIDE (NCT06661044)
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Prostate Adenocarcinoma With Focal Neuroendocrine Differentiation, Prostate Cancer
RET-Targeted Molecular Imaging Probes in Prostate Cancer
The goal of this observational diagnostic imaging study is to evaluate the value of RET-targeted PET/CT molecular imaging in diagnosing neuroendocrine prostate cancer (NEPC) and in assessing disease activity, treatment response…
- Trial name
- NCT07886138
- Testing
- RET-targeted PET/CT molecular imaging, PSMA-targeted PET/CT imaging
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Prostate Adenocarcinoma
Feasibility of Patient-Centered Home Care (PCHC) to Reduce Disparities in High-Risk Black Men (BM) With Prostate Cancer (CaP)
This study evaluates the possibility of patient-centered home care as a new model of cancer care to reduce disparities and improve health related quality of life and patient-reported outcomes in Black patients with prostate…
- Trial name
- NCT06470750
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Prostate Adenocarcinoma, Prostate Carcinoma
DNA Methylation in Adenocarcinoma of the Prostate: Analysis of Validated Biomarkers in Urine
This study explores the potential use of DNA markers in the detection of prostate cancer and patient perceptions of this screening approach and other current or future prostate cancer screening and diagnostic tests.
- Trial name
- NCT06347809
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Prostate Disease, Malignancy
Self-Administered Nitrous Oxide (SANO) During Transrectal Prostate Biopsy to Reduce Patient Anxiety and Pain
Transrectal prostate biopsy is a commonly performed ambulatory procedure for diagnosing prostate cancer. Prostate biopsy are associated with pain or anxiety.
- Conditions
- Prostate Disease, Malignancy, Benign Prostatic Hyperplasia, Prostate Cancer
- Trial name
- NCT05803096
- Testing
- Self-Administered Nitrous Oxide, Oxygen
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Benign Prostate Hypertrophy(BPH), Prostate Cancer (Adenocarcinoma)
Investigation of the Diagnostic Role of miRNAs in PCa and BPH
Prostate cancer(PCa) is the second most common cause of cancer-related death in men after lung cancer. Diagnostic methods such as measurement of serum Prostate-specific antigen (PSA) levels used in the clinic still cannot…
- Trial name
- NCT06726070
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8
rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance
This clinical trial evaluates whether positron emission tomography-magnetic resonance imaging (PET-MRI) using the radioactive drug radiohybrid prostate-specific membrane antigen (rhPSMA)-7.3 may help in detecting higher grade or…
- Conditions
- Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8, Stage IIA Prostate Cancer AJCC v8, Stage IIB Prostate Cancer AJCC v8
- Trial name
- NCT05852041
- Testing
- Biopsy of Prostate, Decipher Prostate Cancer Test, Flotufolastat F-18 Gallium
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Prostate Adenocarcinoma, Metastatic Prostate Adenocarcinoma
Bipolar Androgen Therapy (BAT) and Radium-223 (RAD) in Metastatic Castration-resistant Prostate Cancer (mCRPC)
This is a single-arm, multicenter open label, international, phase II study of Bipolar Androgen Therapy (BAT) plus Radium-223 (RAD) in men with metastatic castration-resistant prostate cancer (mCRPC).
- Conditions
- Prostate Adenocarcinoma, Metastatic Prostate Adenocarcinoma, Castration-resistant
- Trial name
- BAT-RAD (NCT04704505)
- Testing
- radium-223, Bipolar Androgen Therapy (BAT)
- Where
- 2 sites in United States, Brazil
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Prostate Cancer
Observation of Outcomes and Side Effects of Cesium-131 in Combination With External Beam Radiation for the Treatment of Intermediate to High Risk Prostate Cancer
The purpose of this study is to observe PSA response and incidence of side effects in patients diagnosed with intermediate to high risk prostate cancer and treated with Cesium-131 in combination of external beam therapy.
- Trial name
- NCT00621413
- Where
- 9 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- IsoRay Medical, Inc.
Prostate Cancer, Prostate Neoplasm
Early and Accurate Detection of Prostate Cancer in General Practice
Prostate cancer (PC) is the most common malignancy (4500 new cases/year) and the second leading cause of cancer-associated mortality (1200 deaths/year) among men in Denmark.
- Conditions
- Prostate Cancer, Prostate Neoplasm, Prostate Adenocarcinoma
- Trial name
- NCT03431753
- Testing
- PSA, STHLM3 and mpMRI for PC detection
- Where
- Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Breast Cancer, Colorectal Cancer
Family Quality of Life Among Families With a Member Who is a Cancer Patient
RATIONALE: Developing a questionnaire that can be used to assess the quality of life among people who have a family member with cancer may help the study of cancer in the future.
- Conditions
- Breast Cancer, Colorectal Cancer, Head and Neck Cancer, Lung Cancer
- Trial name
- NCT00544336
- Testing
- questionnaire administration, survey administration, quality-of-life assessment
- Where
- 3 sites in United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Prostate Cancer
Comparative Study of Radiotherapy Treatments to Treat High Risk Prostate Cancer Patients
In North America, the number of new cases of prostate cancer increases every year. Many efforts have been made to develop more efficient and safer curative treatments for high risk prostate cancer patients.
- Trial name
- NCT02303327
- Testing
- EBRT + HDR brachytherapy boost, Hypofractionated Dose Escalation Radiotherapy, Androgen deprivation therapy
- Where
- 12 sites in Canada
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Prostate Cancer, Carcinoma of the Rectum
Minocycline Attenuate Postoperative Cognitive Dysfunction and Delirium
Postoperative cognitive dysfunction (POCD) and postoperative delirium occurs mainly in aged patients. POCD and POD may increase the mortality and morbidity.
- Conditions
- Prostate Cancer, Carcinoma of the Rectum, Colon Cancer, Renal Carcinoma
- Trial name
- MAPOCD (NCT02928692)
- Testing
- Minocycline
- Where
- 5 sites in China
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Prostate Cancer, Prostate Adenocarcinoma
Defining Recurrent Disease With Axumin™
This project seeks to use advanced imaging (specifically, positron emission tomography/computed tomography [PET/CT]) to detect, locate, and characterize recurrent disease in the setting of patients with prostate cancer.
- Trial name
- NCT03996993
- Testing
- Casodex, Axumin, Salvage Radiation, Axumin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cancer Center of Irvine
Bladder Cancer, Glioma
Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer
The objective of this study is to assess two novel positron emission tomography (PET) radiotracers, [64Cu]CM500 and [68Ga]CM500, for Positron Emission Tomography-Magnetic Resonance Imaging (PET-MR) and Positron Emission…
- Conditions
- Bladder Cancer, Glioma, Glioblastoma (GBM), Breast Cancer
- Trial name
- NCT07781852
- Testing
- [64Cu]CM500, [68Ga]CM500, PET/MR
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lumina Pharmaceuticals Inc
Ischemic Heart Disease, Prostate Adenocarcinoma
Ischemic Heart Disease in Male With Prostate Adenocarcinoma
The purpose of the study: to increase the efficiency of diagnosis, treatment and prediction of the course of coronary heart disease in patients with adenocarcinoma of the prostate gland, depending on the hormonal status by…
- Trial name
- NCT03474835
- Testing
- ISCHEMIC HEART DISEASE diagnostic
- Where
- Ukraine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dnipropetrovsk State Medical Academy
Prostate Adenocarcinoma
Phase II Trial of SBRT + or - IMRT in Treatment of Patients With Clinically Confined Prostate Adenocarcinoma
Patients with locally confined prostate adenocarcinoma (clinical stage T1c - T2bN0M0, Gleason score 7, PSA 20 ng/ml) are assigned to one of two treatment arms.
- Trial name
- NCT02339948
- Testing
- SBRT
- Where
- 4 sites in United States
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- GenesisCare USA
Prostate Adenocarcinoma, Obesity, Morbid
Bariatric Arterial Embolization for Men Starting Hormones for Prostate Cancer
The standard of care for obese men starting Androgen deprivation therapy (ADT) is physician based dietary and exercise counseling. Interventions to lessen the harmful effects of ADT are needed yet have been limited.
- Trial name
- BASH-PC (NCT04331717)
- Testing
- Bead Block 300-500 um, Weight Management, Lupron
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Prostate Cancer Adenocarcinoma, Erectile Dysfunction Following Radical Prostatectomy
Use of Indocyanine Green in Robotic Prostate Surgeries
Imaging of the vascular nerve bundle using Indocyanine Green
- Trial name
- NCT05960149
- Testing
- using Indocyanine Green, Nerve-sparing robot-assisted laparoscopic radical prostatectomy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara University
Prostate Cancer, Sexual Dysfunction
Tadalafil in Preventing Erectile Dysfunction in Patients With Prostate Cancer Treated With Radiation Therapy
RATIONALE: Tadalafil may help prevent erectile dysfunction (ED) in patients with prostate cancer that has been treated with radiation therapy.
- Trial name
- NCT00931528
- Testing
- Tadalafil
- Where
- 192 sites in United States, Canada
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Radiation Therapy Oncology Group