Clinical trials: Adenoma Detection Rate
Colorectal Polyp, Colonoscopy
Synergistic Effect of G-Eye Balloon for Behind the Folds Visualization With CADe (Discovery System) on Adenoma Detection Rate.
Colonoscopy is the gold standard for colorectal screening. The diagnostic accuracy of colonoscopy highly depends on the quality of inspection of the colon during the procedure.
- Conditions
- Colorectal Polyp, Colonoscopy, Artificial Intelligence, Adenoma
- Trial name
- DiscoveryIII (NCT05220345)
- Testing
- colonoscopy assisted by both balloon-Behind The Folds visualizing and Computer assisted detection (CADe)
- Where
- Netherlands
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Adenoma
Comparing the ADR With Air Insufflation, Water Immersion and Water Exchange During Two-endoscopist Colonoscopy
Interval (missed) cancers and lower than expected mortality reduction of proximal colon cancers in the United States and elsewhere after screening colonoscopy drew attention to quality indicators.
- Trial name
- NCT02737514
- Testing
- Air insufflation, water immersion, water exchange
- Where
- 2 sites in United States, Taiwan
- Volunteers
- 371 people
- Sponsor
- Dalin Tzu Chi General Hospital
Colonic Polyp
Trainee Participation Increases Colon Adenoma Detection Rate
Previous studies that examined whether the presence of an additional observer, more specifically a GI fellow, during colonoscopy can enhance detection of all polyps and adenomas yielded conflicting results.
- Trial name
- ADR (NCT03908229)
- Testing
- Trainee colonoscopy, Experienced physician colonoscopy
- Where
- 4 sites in Italy
- Volunteers
- 812 people
- Sponsor
- Ospedali Riuniti di Foggia
Colonic Polyps, Adenomatous Polyps
Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate
Detection and removal of polyps during colonoscopy is crucial for the prevention of colorectal cancer. Indigo carmine spraying up to the colonic mucosa could probably increase the adenoma detection rate, but considering the long…
- Conditions
- Colonic Polyps, Adenomatous Polyps, Adenoma Detection Rate, Chromoendoscopy
- Trial name
- NCT06961149
- Testing
- Chromoendoscopy with indigo carmine solution spray, Linked-color imaging endoscopy
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Shandong University
Colorectal Neoplasms, Adenoma Detection Rate
Impact of Proximal Colon Retroflexion in Colorectal Cancer Screening Programme
Colorectal cancer (CRC) is the most common tumor and the second leading cause of death in the Western world. The decrease in incidence and mortality by CRC in the population undergoing screening has been observed.
- Trial name
- NCT03041532
- Testing
- Proximal retroflexion, Frontal view
- Where
- Spain
- Volunteers
- 692 people
- Sponsor
- Hospital del Rio Hortega
Colon Polyp
Combined Chromoendoscopy and Water Method for Screening Colonoscopy
In a RCT in screening colonoscopy subjects, we will determine if chromoendoscopy using a dilute solution of Indigocarmine (IC) delivered by the water method (study method) will improve adenoma detection rate compared with the…
- Trial name
- NCT01383265
- Testing
- Water method and chromoendoscopy, Water method
- Where
- United States
- Volunteers
- 1,177 people
- Sponsor
- VA Northern California Health Care System
Adenomatous Polyps
Comparison of Two Devices During Colonoscopy
Colonoscopy is the gold standard investigation for the diagnosis of bowel pathology and colorectal cancer screening. Adenoma detection rate is a marker of high quality colonoscopy.
- Trial name
- COLONAUX (NCT03197987)
- Testing
- Endocuff, cap
- Where
- Spain
- Volunteers
- 710 people
- Sponsor
- Hospital General Universitario Elche
Colonoscopy Education
Comparing Clinical Performance of Novice Trainee Endoscopists Using Conventional Air Insufflation Versus Warm Water Infusion Colonoscopy
Hypothesis: Novice trainees will achieve significantly higher clinical competence and patient satisfaction scores with the use of warm water infusion method when compared with traditional air insufflation Primary outcome: adenoma…
- Trial name
- NCT01482546
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Quality of Bowel Preparation
Effect of Simethicone on Colon Preparation During Water Exchange Colonoscopy
Background: Colonoscopy reduces colorectal cancer mortality by enabling early detection and removal of adenomas. Its effectiveness, however, depends heavily on bowel preparation quality and mucosal visibility.
- Trial name
- NCT07674160
- Testing
- Simethicone with PEG, PEG
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Colon Adenoma, Colonic Polyp
Linked Color Imaging (LCI) for Colorectal Adenoma Detection
Linked color imaging (LCI) is newly developed image-enhancing endoscopy technology that differentiates the red color spectrum more effectively than white light imaging thanks to its optimal pre-process composition of light…
- Trial name
- NCT03690297
- Testing
- Linked Color Imaging
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Valduce Hospital
Colorectal Neoplasms, Colonic Polyps
Evaluation of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for Detection and Optical Characterization of Colorectal Lesions: A Prospective Randomized Controlled Study
This prospective randomized controlled study aims to evaluate the diagnostic accuracy of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for detection and optical characterization of…
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Adenoma, Serrated Polyps
- Trial name
- INSIGHT (NCT07797361)
- Testing
- White Light Endoscopy, Versatile Intelligent Staining Technology, Spectral Flexible Imaging
- Where
- Brazil
- Volunteers
- 990 people
- Sponsor
- Alexandre Vontobel Padoin
Colorectal Adenoma, Colorectal Polyp
To Compare Artificial Intelligence Software Aided Adenoma Detection in Screening Colonoscopies Versus Standard Colonoscopy Without Artificial Intelligence Software Assistance in Participants Between 45 and 75 Years of Age
The aim of this study is to assess the efficacy of Ultivision Artificial Intelligence (AI) Software in detecting adenomas in screening colonoscopy procedures. The safety of Ultivision AI Software will also be assessed.
- Conditions
- Colorectal Adenoma, Colorectal Polyp, Colorectal Adenocarcinoma, Colorectal SSA
- Trial name
- AIDA (NCT04196088)
- Testing
- Ultivision Artificial Intelligence Software, No Artificial Intelligence Software enhancement
- Where
- 9 sites in United States
- Volunteers
- 978 people, healthy volunteers welcome
- Sponsor
- Docbot, Inc.
Quality Indicators, Health Care, Colonoscopy Diagnostic Techniques and Procedures
The Implementation of Computer-aided Detection in Training Improves the Quality of Future Colonoscopies
Computer-aided detection (CADe) based on artificial intelligence (AI) may improve colonoscopy quality. An increasing number of young endoscopists are trained in an AI environment.
- Conditions
- Quality Indicators, Health Care, Colonoscopy Diagnostic Techniques and Procedures, Artificial Intelligence (AI)
- Trial name
- NCT06623331
- Testing
- AI-enhanced endoscopy training, Conventional endoscopy training
- Where
- Poland
- Volunteers
- 6,000 people
- Sponsor
- Jagiellonian University
Adenoma, Colorectal Cancer
Comparison of Adenoma Detection Rate With ENDOCUFF VISION® vs. G-EYE®
The study is intended to compare the detection rate obtained by performing G-EYE® high definition colonoscopy vs. the detection rate obtained by performing ECV high definition colonoscopy.
- Trial name
- NCT04708951
- Testing
- ENDOCUFF VISION® device, G-EYE® colonoscope
- Where
- 3 sites in United States, Germany
- Volunteers
- 970 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Colon Adenomas, Colon Polyps
Impact of Computer-aided Detection System on the Right Colon Adenoma Miss Rate
This is a prospective, multicenter randomized controlled trial designed to determine whether the use of computer-aided detection system could reduce the miss rates of adenomas, SSLs, and polyps in the proximal colon during tandem…
- Conditions
- Colon Adenomas, Colon Polyps, Sessile Serrated Lesion
- Trial name
- NCT07308743
- Testing
- Computer-aided detection-assisted colonoscopy, Conventional white-light colonoscopy
- Where
- China
- Volunteers
- 686 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Colonic Adenomas
Does the Hyoscine N-Butylbromide Administered During Colonoscopy Increase the Adenoma Detection Rate?
The primary aim of the study was to test if the administration of Hyoscine Butyl Bromide, at time of caecal intubation, increases the adenoma detection rate.
- Trial name
- NCT01609855
- Testing
- Hyoscine Butyl Bromide 20mg/2 ml i.v., Saline 2 ml i.v.
- Where
- 2 sites in Italy
- Volunteers
- 400 people
- Sponsor
- Valduce Hospital
Pain, Colorectal Adenomas
A Comparison of Air Insufflation, Water Immersion and Water Exchange Colonoscopy in Diagnostic Patients
Water-aided method for colonoscopy can be broadly subdivided into two major categories. Water Immersion (WI), characterized by suction removal of the infused water predominantly during the withdrawal phase of colonoscopy, and…
- Conditions
- Pain, Colorectal Adenomas, Colorectal Cancer
- Trial name
- NCT01781650
- Testing
- Air Insufflation method., Water Immersion method., Water Exchange method.
- Where
- 3 sites in United States, Italy
- Volunteers
- 288 people
- Sponsor
- Presidio Ospedaliero Santa Barbara
Adenoma Detection Rate
Artificial Intelligence Aid Systems in Colorectal Adenoma Detection
The main purpose of the study to evaluate the usefulness of the Endo-AID artificial intelligence system in the detection of colorectal adenomas in consecutive patients for outpatient colonoscopy.
- Trial name
- INTELAID (NCT04945044)
- Testing
- Computed adenoma detection system (CADe), Control group (regular colonoscopy)
- Where
- Spain
- Volunteers
- 370 people
- Sponsor
- Hospital Universitario de Canarias
Colonic Neoplasms, Adenomas Serrated
Detection in Tandem Endocuff Cap Trial
A randomised back to back study comparing cap and Endocuff to detect adenomas during colonoscopy
- Conditions
- Colonic Neoplasms, Adenomas Serrated, Colo-rectal Cancer, Colon Adenoma
- Trial name
- DETECT (NCT03254498)
- Testing
- Endocuff, cap assisted colonoscopy (CAC)
- Where
- United Kingdom
- Volunteers
- 154 people
- Sponsor
- London North West Healthcare NHS Trust
Colorectal Polyps, Colorectal Adenomas
Endocuff-assisted Versus Cap-assisted Versus Standard Colonoscopy
Comparison of Endocuff-assisted, Cap-assisted and Standard colonoscopy for assessment of the adenoma detection rate (ADR)
- Trial name
- EC-Cap-SC (NCT02331836)
- Testing
- Arc Endocuff (AEC 110, 120, 130, 140), Cap, Standard colonoscope
- Where
- 6 sites in Germany, Poland
- Volunteers
- 561 people
- Sponsor
- Helios Albert-Schweitzer-Klinik Northeim