Clinical trials: Adenomas Serrated
Colonic Polyp, Colorectal Polyp
COLO-DETECT: Can an Artificial Intelligence Device Increase Detection of Polyps During Colonoscopy?
COLO-DETECT is a clinical trial to evaluate whether an Artificial Intelligence device ("GI Genius", manufactured by Medtronic) can identify more polyps (pre-cancerous growths of the bowel lining) during colonoscopy (large bowel…
- Conditions
- Colonic Polyp, Colorectal Polyp, Colorectal Adenoma, Colorectal Adenomatous Polyp
- Trial name
- NCT04723758
- Testing
- GI Genius-assisted diagnostic colonoscopy, Diagnostic Colonoscopy
- Where
- 10 sites in United Kingdom
- Volunteers
- 2,032 people
- Sponsor
- South Tyneside and Sunderland NHS Foundation Trust
Colonic Polyps, Colon Neoplasms
Precision of Optical Diagnosis in Polyps Between 5-15 mm and Its Implications on Surveillance. A Prospective, Multicenter Study.
This study evaluates the ability of endoscopists to perform a complete optical diagnosis of colorectal polyps between 5 and 15 mm, and the impact of the only endoscopic diagnosis on the follow-up program for those patients.
- Conditions
- Colonic Polyps, Colon Neoplasms, Colon Cancer, Serrated Adenoma
- Trial name
- POPS (NCT04232176)
- Where
- Spain
- Volunteers
- 545 people
- Sponsor
- University Hospital Virgen de las Nieves
Adenoma, Colonoscopy
Effect of Two Colonoscopy AI Systems for Colon Polyp Detection
Computer-aided detection (CADe) systems have been actively researched for polyp detection in colonoscopy. The investigators aim to identify the effect of two CADe systems according to the system performance on false positive rate
- Conditions
- Adenoma, Colonoscopy, Sessile Serrated Adenoma
- Trial name
- NCT05089071
- Testing
- Assist by artificial intelligence system for colon polyp detection
- Where
- South Korea
- Volunteers
- 3,046 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Colorectal Neoplasms, Adenoma Colon
Surveillance Intervals After Piecemeal Resection of Non-pedunculated Colorectal Lesions ≥20mm
Intensive endoscopic surveillance following piecemeal resection of non-pedunculated colorectal lesions (NPCL) ≥20 mm is the current standard of care, given the high recurrence rate of these lesions (15-30%).
- Conditions
- Colorectal Neoplasms, Adenoma Colon, Colonic Polyps, Serrated Adenoma
- Trial name
- NCT06791616
- Testing
- Colonoscopy
- Volunteers
- 746 people
- Sponsor
- Asociación Española de Gastroenterología
Colon Adenoma, Colorectal Carcinoma
NBI Versus White Light Endoscopy for Optical Characterization of Neoplastic Polyps in the Colorectum
Adenomas, serrated adenomas and hyperplastic polyps are polypoid lesion in the colorectum. At the present moment, all polyps should be resected endoscopically, although only adenomas and serrated adenomas, but not hyperplastic…
- Conditions
- Colon Adenoma, Colorectal Carcinoma, Hyperplastic Polyp, Serrated Adenoma
- Trial name
- ADOPTION II (NCT03679429)
- Testing
- NBI Function
- Where
- 3 sites in Germany
- Volunteers
- 370 people
- Sponsor
- Technical University of Munich
Colorectal Polyps
AI in Predicting Polyp Pathology and Endoscopic Classification
Background: Colonoscopy with optical diagnosis based on the appearance of polyps can guide the selection of endoscopic treatment methods, reduce unnecessary polypectomy procedures and the need for tissue pathological diagnosis…
- Trial name
- NCT06773832
- Testing
- Real-time Artificial Intelligence Model for Diagnosing Colorectal Polyp Pathology and Endoscopic Classification
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Colon Polyps
Prospective Study of Colon Serrated Polyps
With this study, the investigators plan to review the clinical, epidemiology, pathology, and endoscopic features of colon serrated lesions as well as outcome of endoscopic resection of these lesions.
- Trial name
- NCT02332785
- Testing
- Data Collection
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- M.D. Anderson Cancer Center
Sessile Serrated Adenoma/Polyps
Usefulness of NBI for Complete Endoscopic Resection of SSA/P
This study is a prospective randomized study to evaluate the role of NBI for improving complete resection rate of sessile serrated adenoma/polyp (SSA/P).
- Trial name
- NCT03761667
- Testing
- Endoscopy using Narrow band imaging
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Serrated Polyps, Sessile Serrated Adenoma
Study of Narrow Band Imaging in the Characterization of Serrated Lesions
This study is designed to evaluate the utility of Narrow Band Imaging (NBI) compared with High Definition White Light colonoscopy (WLE) in subjects with serrated lesions who do not fulfill the diagnostic criteria of Serrated…
- Conditions
- Serrated Polyps, Sessile Serrated Adenoma, Colorectal Neoplasms
- Trial name
- CROMOSER (NCT02406547)
- Testing
- NBI, WLE
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- Parc de Salut Mar
Sessile Serrated Adenoma
Prediction of Dysplasia Within Sessile Serrated Polyps Using Endoscopic Imaging; a Prospective Observational Study
Study of endoscopic imaging in the detection of dysplasia within serrated colonic lesions >= 8mm in size
- Trial name
- SERRESH (NCT03100552)
- Testing
- Endoscopic imaging
- Where
- Australia
- Volunteers
- 86 people
- Sponsor
- Western Sydney Local Health District
Colorectal Cancer, Serrated Adenomas
Acetic Acid Colonoscopy Enhancement Study
The purpose of this study is to compare the additional diagnostic yield obtained by using the acetic acid as vital substance to improve the detection of serrated lesions at colonoscopy.
- Conditions
- Colorectal Cancer, Serrated Adenomas, Colon Nos Polypectomy Tubular Adenoma
- Trial name
- NCT02231385
- Testing
- Acetic Acid
- Where
- 2 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Istituto Clinico Humanitas
Colorectal Serrated Adenomas, Colorectal Tubular Adenomas
Minimizing the Risk of Metachronous Adenomas of the Colorectum With Green Tea Extract -MIRACLE-
This is a randomized, placebo controlled, multicentric trial to investigate the effect of diet supplementation with green tea extract containing 300mg epigallocatechin gallate (EGCG), the major polyphenol of green tea, on the…
- Conditions
- Colorectal Serrated Adenomas, Colorectal Tubular Adenomas, Colorectal Villous Adenomas, Colorectal Tubulovillous Adenomas
- Trial name
- MIRACLE (NCT01360320)
- Testing
- Green tea extract of Camellia Sinensis
- Where
- 21 sites in Germany
- Volunteers
- 1,001 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Adenoma Colon, Serrated Adenoma
Does Inspection of Colonic Mucosa During Insertion Improve Adenoma Detection?
This is a prospective randomised controlled trial to assess an intervention of inspection during both phases of colonoscopic examination ( insertion and withdrawal) improve adenoma detection rate when compared to inspection only…
- Trial name
- INWARD (NCT03254030)
- Testing
- Colonic inspection
- Where
- United Kingdom
- Volunteers
- 490 people
- Sponsor
- London North West Healthcare NHS Trust
Polyposis
Endocuff for Surveillance of Serrated Polyposis Syndrome
Serrated Polyposis Syndrome (SPS) is a high-risk condition for colorectal cancer (CRC). SPS patients have a cumulative CRC risk of 1.9% in 5 years despite a strict endoscopic surveillance in specialized centers.
- Trial name
- NCT02592603
- Testing
- Endocuff-assisted Colonoscopy
- Where
- Spain
- Volunteers
- 125 people
- Sponsor
- Hospital Clinic of Barcelona