Clinical trials: Adenomyosis, active
Adenomyosis
Risk Factors Associated With the Progression of Adenomyosis
Adenomyosis is a gynaecological disorder with a high prevalence in women of childbearing age and is characterised by the presence of endometrial glands and stroma within the myometrium, associated or not with hypertrophy and…
- Trial name
- NCT06718088
- Where
- Italy
- Volunteers
- 258 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Uterine Adenomyosis
Efficacy of Uterine Artery Embolization (UAE) in Management of Symptomatic Uterine Adenomyosis
Aim of the work: Evaluating the efficiency of uterine artery embolization as a minimally invasive method of treatment in management of symptomatic women with uterine adenomyosis
- Trial name
- NCT06652945
- Testing
- Uterine artery embolization
- Volunteers
- 30 people
- Sponsor
- Assiut University
Abnormal Uterine Bleeding Due to Adenomyosis (Disorder)
Radiofrequency Endometrial Ablation or Uterine Artery Embolization for Treatment of Adenomyosis-related Abnormal Uterine Bleeding
The present study aims to compare the efficacy (menstrual blood loss, pain, quality of life) and the safety (complications, recovery) of each conservative intervention (RFA, UAE) versus hysterectomy for the treatment of…
- Trial name
- ADENOTREAT (NCT07195305)
- Testing
- Radiofrequency endometrial ablation, Uterine artery embolization, Hysterectomy
- Where
- 4 sites in France
- Volunteers
- 230 people
- Sponsor
- University Hospital, Bordeaux
Abnormal Uterine Bleeding, Unspecified, Benign Gynecological Disease
The Learning Curve of a Gynecology and Obstetrics Resident Performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) Hysterectomy in a University Hospital
This prospective observational study aims to evaluate the learning curve of obstetrics and gynecology residents performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) hysterectomy in a university hospital…
- Conditions
- Abnormal Uterine Bleeding, Unspecified, Benign Gynecological Disease, Adenomyosis of Uterus, Uterine Leiomyomas
- Trial name
- LC of V-NOTES (NCT07465822)
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Cukurova University
Pelvic Pain Syndrome, Endometriosis
The Good Pain Consultation in Endometriosis.
This PhD project investigates the effect of "the good pain consultation" and early integration of biopsychosocial pain education with current standard management of endometriosis.
- Conditions
- Pelvic Pain Syndrome, Endometriosis, Dysmenorrhea, Adenomyosis
- Trial name
- NCT07205614
- Testing
- pain consultation, biopsychosocial pain education + usual care, Usual Care
- Where
- Norway
- Volunteers
- 110 people
- Sponsor
- Sorlandet Hospital HF
Adenomyosis, Adenomyoma of Uterus
Ultrasound-Guided Radiofrequency Ablation for Focal Adenomyosis
This single-center, single-arm, open-label study evaluates the efficacy and safety of ultrasound-guided radiofrequency ablation (RFA) in women with symptomatic focal adenomyosis who wish to preserve the uterus.
- Trial name
- RFA-ADENO-USG (NCT07906535)
- Testing
- Myoblate Radiofrequency Ablation System (Mygen V-1000 generator)
- Where
- Czechia
- Volunteers
- 41 people
- Sponsor
- University Hospital Pilsen
Adenomyosis of Uterus, Frozen Embryo Transfer (FET)
GnRH Agonist Pretreatment Duration and Letrozole Supplementation in Frozen Embryo Transfer for Adenomyosis Patients
This randomized clinical trial aims to assess the comparative effectiveness of different pre-treatment protocols prior to frozen embryo transfer (FET) among women with adenomyosis, providing evidence-based guidance for clinical…
- Trial name
- GOLD-FET (NCT07065539)
- Testing
- GnRH-a-1M, GnRH-a-2M, GnRH-a+LE-1M
- Where
- China
- Volunteers
- 432 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Adenomyosis, Fibroid Uterus
Fertility Limiting Diseases of Pelvic Organs and Their Influence on Receptivity of Endometrial Cavity: Prospective Clinical Trial
In this project, we will characterize the effects of fertility limiting diseases of pelvic organs on the receptivity of the endometrium.
- Conditions
- Adenomyosis, Fibroid Uterus, Endometriosis
- Trial name
- REAdME (NCT06991595)
- Testing
- cytoreductive resection of adenomyosis, myomectomy, resection of endometriosis, hysteroscopy
- Where
- Czechia
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Myoma;Uterus, Adenomyosis of Uterus
RCT - Efficacy of Intravenous Vitamin C Versus Placebo on Estimated Blood Loss in Total Abdominal Hysterectomy
Intervention Group: Received two 1 gm doses of Vitamin C intravenously (IV). first Dose: At midnight on the day of surgery. Second Dose: Immediately after the surgical incision.
- Trial name
- Vit C in TAH (NCT07335432)
- Testing
- Vitamin C (Ascorbic Acid)
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Adenomyosis of Uterus
Evaluation of the Efficacy and Safety of Microwave Ablation of Uterine Adenomyosis Under Improved Ultrasound Guidance
This study aims to compare the safety and efficacy of segmental power adjustment combined with uterine cavity hydro-isolation in microwave ablation of adenomyosis
- Trial name
- NCT06751264
- Testing
- Peritoneal combined with intrauterine water isolation, Peritoneal water isolation
- Where
- China
- Volunteers
- 137 people
- Sponsor
- Peking University Aerospace Center Hospital
Adenomyosis of Uterus, Uterine Diseases
Multicenter Observational Cohort Study on the Epidemiology of Therapeutic Strategies in Patients Affected by Adenomyosis
The primary objective of this multicenter observational cohort study is to evaluate the current medical approach to the management of adenomyosis in women, with particular focus on treatment selection and treatment persistence.
- Conditions
- Adenomyosis of Uterus, Uterine Diseases, Gynecologic Diseases, Menorrhagia, Dysmenorrhea
- Trial name
- Adenomyosis (NCT07478614)
- Testing
- This is a non-interventional study. Treatment allocation will not be influenced by the study protocol.
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- SCHETTINI SERGIO
Adenomyosis, Quality of Life
Quality of Life After Hysterectomy (AdenoQOL)
Adenomyosis is a disease where ectopic endometrial-like glands affect the muscular wall of the uterus. About 70% of women affected by adenomyosis suffer from dysmenorrhea and menorrhagia.
- Trial name
- NCT04791033
- Testing
- Hysterectomy
- Where
- Norway
- Volunteers
- 218 people
- Sponsor
- Oslo University Hospital
Endometriosis
ENDOmetriosis Robotic Assisted Surgery
The purpose of this study is to compare the robot-assisted approach with the laparoscopic approach in terms of reducing the rates of intraoperative and postoperative complications in patients undergoing total hysterectomy for DIE…
- Trial name
- ENDO-RAS (NCT06445179)
- Testing
- Total Laparoscopic Hysterectomy, Ureterolysis
- Where
- 2 sites in France
- Volunteers
- 224 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Fibroid Uterus, Metrorrhagia
A Randomized Study Comparing Subtotal vs Total Hysterectomy Long Term Outcomes
The goal of this randomized clinical trial is to assess the outcomes of total laparoscopic hysterectomy vs subtotal laparoscopic hysterectomy + mini-laparotomy for uterine extraction for benign gynecological conditions in terms…
- Conditions
- Fibroid Uterus, Metrorrhagia, Adenomyosis, Benign Gynecologic Neoplasm
- Trial name
- STORY (NCT06802198)
- Testing
- total hysterectomy, subtotal hysterectomy
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus
Stellate Ganglion Block and Dexmedetomidine for Postoperative Sleep in Women Undergoing Laparoscopic Gynecologic Surgery
Study Objectives This study aims to investigate the effects of preoperative stellate ganglion block and intraoperative intravenous dexmedetomidine on postoperative sleep disturbance in patients undergoing laparoscopic gynecologic…
- Conditions
- Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus, Endometriosis, Endometrial Cancer
- Trial name
- NCT07860203
- Testing
- DEX 0.2 μg/kg/h., SGB
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Catherin Zhang
Adenomyosis
Ttt of Adenomyosis
to evaluate use of Dienogest versus uterine arteries embolization in treatment of Adenomyosis-associated symptoms as dysmenorrhea, heavy menstrual bleeding and bulk-related symptoms
- Trial name
- NCT06719934
- Testing
- Dienogest 2 mg orally, UAE
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Adenomyosis
Adenomyosis Clinical, Imaging and Histopathology
The goal of this clinical trial is to identify and compare the results of imaging studies and evaluating adenomyosis features and post hysterectomy results and their clinical relievants as well as to describe classification for…
- Trial name
- AM C/I/H (NCT07237932)
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Kafrelsheikh University
Adenomyosis of Uterus
Artificial Intelligence-Based Machine Learning to Diagnose and Classify Adenomyosis from Ultrasound Scans: a Multicentre Model Development Study
The aim of this study is to use the vast dataset of annotated ultrasound images of normal uterus and of adenomyosis of varying severity to train a neural network using deep learning framework (Pytorch) and automated machine…
- Trial name
- NCT06765512
- Testing
- use of deep learning and automated machine learning to diagnose and classify adenomyosis
- Where
- United Kingdom
- Volunteers
- 10,000 people
- Sponsor
- CARE Fertility UK
Endometriosis, Adenomyosis of Uterus
Artificial Intelligence Into Ultrasound Diagnostics in Reproductive Medicine
The goal of this observational study is to develop and validate artificial intelligence (AI)-based algorithms that support ultrasound diagnosis of endometriosis, adenomyosis, myometrial masses, uterine malformations, and impaired…
- Conditions
- Endometriosis, Adenomyosis of Uterus, Leiomyoma (Uterine Fibroids), Uterine Neoplasms
- Trial name
- AUDRIE (NCT07810920)
- Where
- Hungary
- Volunteers
- 1,600 people
- Sponsor
- Semmelweis University
Uterine Fibroids (UF), Menstrual Disorders
Hugo™ Robotic-Assisted Surgery (RAS) System in Gynecological Subjects (Embrace Gynecology)
The purpose of this research is to evaluate the safety and performance of the investigational Medtronic Hugo™ Robotic Assisted Surgery (RAS) system when used during hysterectomy procedures, including patients being treated for…
- Conditions
- Uterine Fibroids (UF), Menstrual Disorders, Adenomyosis of Uterus, Endometriosis
- Trial name
- Embrace Gyn (NCT07120945)
- Testing
- Robotic Assisted-Surgery (RAS) Hysterectomy
- Where
- 5 sites in United States
- Volunteers
- 70 people
- Sponsor
- Medtronic - MITG