Clinical trials: Adenomyosis of Uterus
Adenomyosis
Factors Associated With Adenomyosis and a Clinical Scoring System for the Diagnosis
Adenomyosis is a relatively common benign disorder in which endometrial gland and stroma are located within the myometrium resulting angiogenesis of the spiral vessel, hypertrophy of the surrounding smooth muscles and enlargement…
- Trial name
- NCT04830085
- Testing
- Hysterectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 221 people
- Sponsor
- Mersin University
Endometriosis, Adenomyosis
Next-Generation Endometriosis Diagnostics Through Comprehensive Multi-Dimensional Analysis
This study is a multicentric, observational, case-control, non-profit with additional procedures. It aims to deepen the understanding of the chronic gynecological conditions of endometriosis and adenomyosis, which significantly…
- Trial name
- AdEnd (NCT06572852)
- Testing
- No intervention
- Where
- 2 sites in Italy
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Uterine Myoma, Uterine Adenomyosis
Single Incision Laparoscopic Surgery (SILS) Versus Conventional Laparoscopic Hysterectomy
Multi-center prospective randomized trial of single port laparoscopic surgery (SILS) versus conventional 3-4 ports laparoscopic hysterectomy.
- Trial name
- NCT01483417
- Testing
- Single incision Laparoscopic hysterectomy, Conventional laparoscopic hysterectomy
- Where
- 8 sites in South Korea
- Volunteers
- 240 people
- Sponsor
- Samsung Medical Center
Adenomyosis
A Prospective Study of Diagnostic Accuracy of Ultrasound
Prospectively-Patients undergoing a hysterectomy for abnormal uterine bleeding (AUB) or pelvic pain will be enrolled in the study, will get pelvic ultrasound at the ultrasound clinic.
- Trial name
- NCT03120078
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Adenomyosis
Adenomyosis and ART
The goal of this clinical trial is to: Prospectively investigate the association of Adenomyosis with fertility outcomes in relation to COH protocols for ART (long or ultra- long protocol) with a preventive high-dose…
- Trial name
- ADENOFERT (NCT05937490)
- Testing
- Enantone, Dienogest 2 MG (milligram), long GnRH agonist or flexible GnRH antagonist protocol.
- Where
- Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Endometriosis, Fibroids
Impact of Educational Videos on Pre-operative Anxiety
The goal of this clinical trial is to learn if educational videos can reduce pre-operative anxiety in patients undergoing minimally invasive gynecologic surgery.
- Conditions
- Endometriosis, Fibroids, Adenomyosis, Pelvic Pain
- Trial name
- NCT07740759
- Testing
- educational video
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- UConn Health
Adenomyosis, Abnormal Uterine Bleeding
Adenomyosis: Genomic Mechanisms and Biological Response
Examination of genomic and biologic responses to LNG-IUS in patients with adenomyosis.
- Trial name
- NCT03428854
- Testing
- LNG-IUS
- Sponsor
- University of Texas Southwestern Medical Center
Adenomyosis
Intrauterine Device Versus Uterine Artery Embolization for Adenomyosis
The primary purpose of this study is to compare the therapeutic efficacy of intrauterine device and uterine artery embolization for uterine adenomyosis.
- Trial name
- NCT06043583
- Testing
- Intrauterine device, Uterine artery embolization
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Yonsei University
Endometriosis
Proliferation of Endometrial Stromal Cells in Adenomyosis
Adenomyosis refers to the presence of endometrial glands and stroma that is haphazardly deep within the myometrium. However, the etiology and pathologic mechanism responsible for adenomyosis are not yet very well known.
- Trial name
- NCT00173212
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Adenomyosis, Quality of Life
Quality of Life After Hysterectomy (AdenoQOL)
Adenomyosis is a disease where ectopic endometrial-like glands affect the muscular wall of the uterus. About 70% of women affected by adenomyosis suffer from dysmenorrhea and menorrhagia.
- Trial name
- NCT04791033
- Testing
- Hysterectomy
- Where
- Norway
- Volunteers
- 218 people
- Sponsor
- Oslo University Hospital
Uterine Adenomyosis, Recurrent Implantation Failure
Aromatase Plus GnRH Analogue Versus GnRH Analog Alone in Adenomyosis
With this study the investigators want to test which is the best medical treatment for symptomatic adenomyosis affecting women undergoing IVF and with previous implantation failure, between Aromatase inhibitor plus GnRH analog…
- Conditions
- Uterine Adenomyosis, Recurrent Implantation Failure, Menstrual Pain
- Trial name
- NCT03421639
- Testing
- GnRH analog (11.25mg Leuprolide acetate), Aromatase inhibitor and GnRH analog, Aromatase and GnRH analog (11.25mg Leuprolide acetate)
- Where
- 3 sites in Albania, Bulgaria and 1 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Adenomyosis, in Vitro Fertilization
Cohort Profile：The Shandong Adenomyosis Cohort of Population Undergoing Reproductive Technology (SAart)
Previous studies have shown that compared with infertile women without adenomyosis, the clinical pregnancy rate, live birth rate and continuous pregnancy rate of women with adenomyosis significantly reduce, and the abortion rate…
- Trial name
- NCT06604091
- Testing
- Treatment protocol
- Where
- China
- Volunteers
- 2,241 people
- Sponsor
- The Second Hospital of Shandong University
Adenomyosis
Adenomyosis Patients With Infertility and Immunological Factors
Infertile patients with adenomyosis who met the inclusion and exclusion criteria, after signing the informed consent form, the researchers recorded the clinical information of the patients and initiated the in vitro…
- Trial name
- NCT06123975
- Testing
- Venous blood collection
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Adenomyosis of Uterus
Artificial Intelligence-Based Machine Learning to Diagnose and Classify Adenomyosis from Ultrasound Scans: a Multicentre Model Development Study
The aim of this study is to use the vast dataset of annotated ultrasound images of normal uterus and of adenomyosis of varying severity to train a neural network using deep learning framework (Pytorch) and automated machine…
- Trial name
- NCT06765512
- Testing
- use of deep learning and automated machine learning to diagnose and classify adenomyosis
- Where
- United Kingdom
- Volunteers
- 10,000 people
- Sponsor
- CARE Fertility UK
Adenomyosis
Validation and Optimisation of Ultrasound Diagnosis of Adenomyosis
Defining ultrasound criteria for normal uterine biometry and assessing the prevalence of repeat abortions in patients with abnormalities of the uterine cavity
- Trial name
- NCT06795711
- Where
- Italy
- Volunteers
- 465 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Adenomyosis
Levonorgestrel-releasing Intrauterine System Versus a Low-dose Combined Oral Contraceptive for Management of Adenomyosis Uteri
This study aims to compare the efficacy of LNG - IUD (Levonorgestrel releasing intrauterine device) Versus Low dose COCs (combined oral contraceptive pills) on management of heavy menstrual bleeding and Dysmenorrhea caused by…
- Trial name
- LNG-IUDvsCOCs (NCT03037944)
- Testing
- Yasmin, Metraplant-E
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Ain Shams Maternity Hospital
Intrauterine Device Expulsion, Adenomyosis, Endometriosis
Clinical Observation of Hysteroscopy-Assisted Placement of Handmade Frameless GyneFix-LNG-IUS (Retrospective Cohort)
This is a retrospective self-controlled observational study. We evaluated the safety and efficacy of a handmade frameless levonorgestrel-releasing intrauterine system (GyneFix-LNG-IUS) in patients at high risk of IUD expulsion.
- Conditions
- Intrauterine Device Expulsion, Adenomyosis, Endometriosis, Menorrhagia, Dysmenorrhea, Abnormal Uterine Bleeding
- Trial name
- Gyne-LNG-IUS (NCT07518693)
- Testing
- Handmade Frameless GyneFix-LNG-IUS
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Yu Wang
Adenomyosis
Central Sensitization in Women With Adenomyosis: Prevalence, Risk Factors, and Therapeutic Failure
This is an observational, prospective, multicenter, non-profit study. The study aims to investigate the association between the Central Sensitization Inventory (CSI) score and the presence of Central Sensitization Syndrome (CSS)…
- Trial name
- ADENOCS (NCT07455721)
- Where
- 14 sites in Italy
- Volunteers
- 1,200 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Pelvis Pain Chronic, Endometriosis of Uterus
Functional Brain Imaging and Psychological Testing in Women With Chronic Pelvic Pain
Functional magnetic resonance imaging in women with chronic pelvic pain using arterial spin labelling, functional connectivity, diffusion tensor imaging and magnetic resonance spectroscopy.
- Trial name
- NCT02160483
- Testing
- Functional magnetic resonance imaging
- Where
- Singapore
- Sponsor
- KK Women's and Children's Hospital
Adenomyosis
Role of Uterine Artery Embolization in Adenomyosis
Management of symptomatizing women diagnosed with uterine adenomyosis, by uterine artery angioembolization as a minimally invasive replacement for hysterectomy.
- Trial name
- NCT05597644
- Testing
- Trans-arterial uterine artery embolization
- Volunteers
- 30 people
- Sponsor
- Assiut University