Clinical trials: Adherence, Medication, open to volunteers
Aging, Mild Cognitive Impairment
bpMedManage: Digital Technology to Support Adherence to Hypertension Medications
The purpose of the bpMedManage study is to rigorously test the efficacy of a smartphone technology to help improve high blood pressure medication adherence among older adults with mild cognitive impairment (MCI) in a 16-week…
- Conditions
- Aging, Mild Cognitive Impairment, Hypertension
- Trial name
- NCT06307574
- Testing
- bpMedManage
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Arizona
Medication Adherence
Investigation of a Patient Support Intervention for Statin Medication Adherence
Statins have been demonstrated to significantly reduce the risk of cardiovascular disease, but adherence to these medications is suboptimal.
- Trial name
- NCT06972979
- Testing
- Text Message Gamification and Remote Support
- Where
- United States
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Ascension Health
Atopic Dermatitis
Opzelura Experience Study
Atopic dermatitis is a common multifactorial skin disease. Topicals are the mainstay of treatment, but adherence to topicals is often abysmal, possibly worsened by the complexity of recommended treatment algorithms.
- Trial name
- NCT07661979
- Testing
- ruxolitinib, ruxolitinib and an Eczema Action Plan
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Acute Lymphobkastic Leukemia, Medication Adherence
The AYA Oncology Self-care Movement
This trial will test the impact of a social media intervention for improving oral chemotherapy adherence among adolescents and young adults (AYAs) with acute lymphoblastic leukemia.
- Trial name
- #AYAOSM (NCT07724652)
- Testing
- Educational Website, #AYAOSM
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Cancer
Improving Adherence to Chronic Disease Medication Regimens Among Patients With Recently Diagnosed Cancer
This pilot study evaluates a pharmacist-led medication adherence intervention and Medisafe mobile application among patients with newly diagnosed cancer and multimorbidity.
- Trial name
- NCT07811258
- Testing
- Medisafe Medication Management Program, Pharmacist-Led Medication Review
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Duke University
Type 2 Diabetes
A Two-armed Real-world Study of Ozempic (OW Semaglutide) to Evaluate Its Adherence and Persistence Compared With Other Anti-diabetic Drugs Among Adult T2DM Patients in China
The study is testing the incidence of MACE and incidence of renal events between Ozempic® users and users with other anti-diabetic medications in T2D patients.
- Trial name
- SPOTLIGHT (NCT07456774)
- Where
- China
- Volunteers
- 100,000 people
- Sponsor
- Novo Nordisk A/S
Breast Cancer, Adjuvant Treatment
Evaluating the Use of a Medication 'Switch' vs Guideline-directed Interventions for Relieving Side Effects of Aromatase Inhibitors Among Breast Cancer Patients
Researchers have learned that about 50% of women do not finish the standard 5-year breast cancer treatment with an aromatase inhibitor.
- Conditions
- Breast Cancer, Adjuvant Treatment, Early Stage Breast Cancer
- Trial name
- SWIVEL (NCT07071038)
- Testing
- Switch, Guideline Directed Intervention (GDI)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Cancer
Improving PRO for Patients With Cancer Using ECAs and Data Visualization
Over the past decade, the investigators have developed and tested a toll with the potential to enhance PROs at the individual level- embodied conversational agents (ECA), which are computer characters that simulate face-to-face…
- Trial name
- ECA-PRO Aim 3 (NCT05948618)
- Testing
- Embodied Conversational Agent, REDCap Survey
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Tufts Medical Center
Breast Surgery
Efficacy of Written Versus Video Patient Education Materials for Postmastectomy Breast Reconstruction
This is a prospective, randomized controlled trial evaluating the comparative efficacy of written, video, and combined written and video patient education materials relative to no supplemental education for University of…
- Trial name
- NCT07602374
- Testing
- Questionnaires, Video Health Education Materials, Written Health Education Materials
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
GERD (Gastroesophageal Reflux Disease)
A Comparison of Cosmos Rx Medication Adherence Platform vs. Pharmacy Fill Adherence Measures
Medication non-adherence is associated with greater morbidity and mortality in chronic disease, and has been estimated to increase healthcare costs by over $170 billion annually in the United States.1 Medication adherence is…
- Trial name
- NCT07712614
- Testing
- Fortiskap
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Cosmos Rx, Inc
Hypertension
Sexual Dysfunction in Hypertensive Women
Several studies describe the existence of an association between sexual dysfunction and high blood pressure (hypertension), most often characterized by a decrease in the number of orgasms and the existence of dyspareunia.
- Trial name
- DYSFHO (NCT05156385)
- Testing
- Blood sample for the determination of antihypertensives or their metabolites., Questionnaire on sexual activity, Scale on hospital anxiety and depression
- Where
- France
- Volunteers
- 348 people
- Sponsor
- University Hospital, Toulouse
Cardiovascular Diseases, Cardiac Rehabilitation
SMART to Optimize an Intervention to Maintain Health Improvements After Cardiac Rehabilitation
The study is sponsored by the National Heart, Lung, and Blood Institute, which is part of the National Institutes of Health. The study expects to enroll 400 subjects.
- Trial name
- EMPOWER ME (NCT06886789)
- Testing
- Text Messaging, Fully Automated Online Program, Low-Intensity Cardiac Rehabilitation Maintenance Program
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- The Miriam Hospital
Dementia Family Caregiver, Dementia
Medication Collaboration Feasibility Study
This study examines the feasibility and acceptability of a brief medication collaboration intervention among older adults (age 60+) with early-stage dementia or mild cognitive impairment who take multiple medications and their…
- Conditions
- Dementia Family Caregiver, Dementia, Medication Adherence
- Trial name
- NCT07742189
- Testing
- Medication Collaboration Intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Multiple Myeloma or Amyloidosis
Prospective Evaluation of Subcutaneous Administration of Daratumumab by the FreedomEDGE® Infusion System
This study is evaluating a new method for administering daratumumab, a treatment commonly used in the management of multiple myeloma and amyloidosis.
- Trial name
- ESCAPE (NCT07721350)
- Testing
- Subcutaneous Daratumumab Administration Using FreedomEDGE®
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Elderly (People Aged 65 or More)
The Effect of İnhaler Training and Reminders on Medication on Adherence in Elderly Individuals
This study will evaluate the effect of metered-dose inhaler training and reminders on treatment adherence in elderly individuals.
- Trial name
- NCT07381166
- Testing
- Metered Dose Inhaler Training, Metered Dose Inhaler Reminder Card, Metered Dose Inhaler Application Video
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Çanakkale Onsekiz Mart University
Hypertension, HIV-1-infection
Addressing Barriers to Anti-hypertensive Medication Adherence Among PLWH Who Have Achieved Viral Suppression
Among those with hypertension, persons living with HIV (PWH) have a 50% higher risk of incident myocardial infarction compared to the general population, and they often fail to meet evidence-based treatment goals for…
- Trial name
- NCT05459077
- Testing
- Hypertension control through education and monitoring
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Heart Failure, Heart Failure NYHA Class I
Promoting Well-being and Health in Heart Failure
The focus of this study is to test the efficacy of a 12-week, phone-delivered Positive Psychology-Motivational Interviewing (PP-MI) intervention, with additional twice weekly PP and health behavior text messages for a total of 24…
- Conditions
- Heart Failure, Heart Failure NYHA Class I, Heart Failure NYHA Class II, Heart Failure NYHA Class III
- Trial name
- NCT04829617
- Testing
- PP-MI Intervention, MI-alone Intervention
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Massachusetts General Hospital
Medication Adherence, Medication Safety
Evaluation of Medication Management Service
Medication management services (MMS) is a pharmacist-led service of optimizing the medication use and health outcomes, by promoting medication safety and enhancing the ability in self-management of health and diseases of patients…
- Conditions
- Medication Adherence, Medication Safety, Diabetes Mellitus, Type 2, Hypertension
- Trial name
- NCT06273761
- Testing
- Medication Management Service (MMS)
- Where
- 8 sites in Hong Kong
- Volunteers
- 640 people
- Sponsor
- The University of Hong Kong
Medication Adherence, Breast Cancer
Adjuvant Endocrine Therapy Adherence Intervention Pilot in Rwanda
This study aims to evaluate a multi-modal intervention designed to improve adherence to adjuvant endocrine therapy (AET) among patients with ER-positive breast cancer in Rwanda.
- Trial name
- NCT07562399
- Testing
- Educational video, Symptom monitoring card, Text reminders
- Where
- 4 sites in United States, Rwanda
- Volunteers
- 224 people
- Sponsor
- Dana-Farber Cancer Institute
Hypertension,Essential, Adherence, Medication
Mobile Health Program for Rural Hypertension
Hypertension (HTN) is the leading modifiable cause of cardiovascular disease. Rural individuals experience challenges of the rural health divide: geographic distance from providers, social isolation, limited social resources, and…
- Conditions
- Hypertension,Essential, Adherence, Medication, Quality of Life
- Trial name
- NCT05546931
- Testing
- Coaching application, WebMD, Home-based blood pressure monitoring
- Where
- United States
- Volunteers
- 334 people
- Sponsor
- University of Pittsburgh